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solute carrier family 25 (mitochondrial carrier oxoglutarate carrier), member 11

Summary

Gene Symbol

Slc25a11

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

67863

PubChem

67863

Alliance of Genome Resources

MGI:1915113

Annotation

Keyword

Acetylation
Antiport
Direct protein sequencing
Lipid transport
Mitochondrion inner membrane
Phosphoprotein
Reference proteome
Repeat
Transmembrane helix
Transport

Proteins

Displaying **all 2** entries
UniProt	Protein Name
Q5SX53	Solute carrier family 25 member 11
Q9CR62	Solute carrier family 25 member 11

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 11 in total

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GO Term	Evidence Code	PMID
malate-aspartate shuttle	IMP	31217581
malate transmembrane transport	IBA IEA
succinate transmembrane transport	IBA
gluconeogenesis	IMP ISO	35507647 4687397
thiosulfate transport	IBA

GO Hierarchy

biological process

metabolic process [inference]

biosynthetic process [inference]

small molecule biosynthetic process [inference]

monosaccharide biosynthetic process [inference]

hexose biosynthetic process [inference]

gluconeogenesis

organic substance biosynthetic process [inference]

carbohydrate biosynthetic process [inference]

monosaccharide biosynthetic process [inference]

hexose biosynthetic process [inference]

gluconeogenesis

primary metabolic process [inference]

carbohydrate metabolic process [inference]

monosaccharide metabolic process [inference]

hexose metabolic process [inference]

glucose metabolic process [inference]

gluconeogenesis

hexose biosynthetic process [inference]

gluconeogenesis

monosaccharide biosynthetic process [inference]

hexose biosynthetic process [inference]

gluconeogenesis

carbohydrate biosynthetic process [inference]

monosaccharide biosynthetic process [inference]

hexose biosynthetic process [inference]

gluconeogenesis

small molecule metabolic process [inference]

monosaccharide metabolic process [inference]

hexose metabolic process [inference]

glucose metabolic process [inference]

gluconeogenesis

hexose biosynthetic process [inference]

gluconeogenesis

monosaccharide biosynthetic process [inference]

hexose biosynthetic process [inference]

gluconeogenesis

small molecule biosynthetic process [inference]

monosaccharide biosynthetic process [inference]

hexose biosynthetic process [inference]

gluconeogenesis

organic substance metabolic process [inference]

carbohydrate metabolic process [inference]

monosaccharide metabolic process [inference]

hexose metabolic process [inference]

glucose metabolic process [inference]

gluconeogenesis

hexose biosynthetic process [inference]

gluconeogenesis

monosaccharide biosynthetic process [inference]

hexose biosynthetic process [inference]

gluconeogenesis

carbohydrate biosynthetic process [inference]

monosaccharide biosynthetic process [inference]

hexose biosynthetic process [inference]

gluconeogenesis

organic substance biosynthetic process [inference]

carbohydrate biosynthetic process [inference]

monosaccharide biosynthetic process [inference]

hexose biosynthetic process [inference]

gluconeogenesis

cellular process [inference]

transmembrane transport [inference]

inorganic ion transmembrane transport [inference]

inorganic anion transmembrane transport [inference]

organic acid transmembrane transport [inference]

carboxylic acid transmembrane transport [inference]

mitochondrial transmembrane transport [inference]

malate-aspartate shuttle

localization [inference]

establishment of localization [inference]

transport [inference]

mitochondrial transport [inference]

mitochondrial transmembrane transport [inference]

malate-aspartate shuttle

inorganic anion transport [inference]

phosphate ion transport [inference]

phosphate ion transmembrane transport

sulfate transport

sulfate transmembrane transport

thiosulfate transport

inorganic anion transmembrane transport [inference]

transmembrane transport [inference]

inorganic ion transmembrane transport [inference]

inorganic anion transmembrane transport [inference]

organic acid transmembrane transport [inference]

carboxylic acid transmembrane transport [inference]

mitochondrial transmembrane transport [inference]

malate-aspartate shuttle

organic substance transport [inference]

lipid transport

organic anion transport [inference]

carboxylic acid transport [inference]

dicarboxylic acid transport [inference]

C4-dicarboxylate transport [inference]

oxaloacetate transport

malate transport [inference]

malate transmembrane transport

succinate transport [inference]

succinate transmembrane transport

alpha-ketoglutarate transport

carboxylic acid transmembrane transport [inference]

organic acid transport [inference]

carboxylic acid transport [inference]

dicarboxylic acid transport [inference]

C4-dicarboxylate transport [inference]

oxaloacetate transport

malate transport [inference]

malate transmembrane transport

succinate transport [inference]

succinate transmembrane transport

alpha-ketoglutarate transport

carboxylic acid transmembrane transport [inference]

organic acid transmembrane transport [inference]

carboxylic acid transmembrane transport [inference]

nitrogen compound transport [inference]

sulfate transport

sulfate transmembrane transport

thiosulfate transport

sulfur compound transport [inference]

sulfate transport

sulfate transmembrane transport

thiosulfate transport

Displaying **all 2** entries
GO Term	Evidence Code	PMID
mitochondrial inner membrane	HDA IMP ISO	12865426 35507647 4687397
mitochondrion	HDA	14651853 18614015

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

organelle membrane [inference]

organelle inner membrane [inference]

mitochondrial inner membrane

mitochondrial membrane [inference]

mitochondrial inner membrane

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

mitochondrion

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

mitochondrion

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	PMID
oxaloacetate transmembrane transporter activity	IBA
malate transmembrane transporter activity	IBA
sulfate transmembrane transporter activity	IBA
thiosulfate transmembrane transporter activity	IBA
oxoglutarate:malate antiporter activity	IMP ISO	35507647 4687397

GO Hierarchy

molecular function

transporter activity [inference]

transmembrane transporter activity [inference]

organic acid transmembrane transporter activity [inference]

carboxylic acid transmembrane transporter activity [inference]

dicarboxylic acid transmembrane transporter activity [inference]

oxaloacetate transmembrane transporter activity

alpha-ketoglutarate transmembrane transporter activity

oxoglutarate:malate antiporter activity

malate transmembrane transporter activity

oxoglutarate:malate antiporter activity

succinate transmembrane transporter activity

C4-dicarboxylate transmembrane transporter activity [inference]

oxaloacetate transmembrane transporter activity

malate transmembrane transporter activity

oxoglutarate:malate antiporter activity

succinate transmembrane transporter activity

organic anion transmembrane transporter activity [inference]

carboxylic acid transmembrane transporter activity [inference]

dicarboxylic acid transmembrane transporter activity [inference]

oxaloacetate transmembrane transporter activity

alpha-ketoglutarate transmembrane transporter activity

oxoglutarate:malate antiporter activity

malate transmembrane transporter activity

oxoglutarate:malate antiporter activity

succinate transmembrane transporter activity

C4-dicarboxylate transmembrane transporter activity [inference]

oxaloacetate transmembrane transporter activity

malate transmembrane transporter activity

oxoglutarate:malate antiporter activity

succinate transmembrane transporter activity

inorganic molecular entity transmembrane transporter activity [inference]

inorganic anion transmembrane transporter activity [inference]

sulfate transmembrane transporter activity

active transmembrane transporter activity [inference]

secondary active transmembrane transporter activity [inference]

antiporter activity

oxoglutarate:malate antiporter activity

sulfur compound transmembrane transporter activity [inference]

salt transmembrane transporter activity [inference]

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Rodentia

Group Name

mitochondrial 2-oxoglutarate/malate carrier protein

Functional Category

G: Carbohydrate transport and metabolism
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 2** entries
InterPro
Mitochondrial carrier domain superfamily
Mitochondrial substrate/solute carrier

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:0050773	paraganglioma	Alliance of Genome Resources

Ortholog

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Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Homo sapiens	8402		HGNC:10981	HUMAN31007
Drosophila melanogaster	38571		FB:FBgn0035567
Drosophila melanogaster	38572		FB:FBgn0035568
Drosophila melanogaster	43483		FB:FBgn0039674
Rattus norvegicus	64201	10116_1:00352a	RGD:708476	RATNO00161
Caenorhabditis elegans	173414		WB:WBGene00015186
Bos taurus	282523			BOVIN12664
Sus scrofa	397390			PIGXX03229
Danio rerio	415189		ZFIN:ZDB-GENE-040625-79	DANRE35826
Pan troglodytes	468167			PANTR13318