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Standards Ontologies Notations
cytochrome P450 family 1 subfamily A member 1

Summary
Gene Symbol
  • CYP1A1
Organism
Macaca mulatta (Rhesus monkey)
External Links
NCBI Gene
678694
KEGG Gene ID
mcc:678694
PubChem
678694
Annotation
Keyword
  • Cytoplasm
  • Glycoprotein
  • Heme
  • Lyase
  • Microsome
  • Mitochondrion inner membrane
  • Monooxygenase
  • Reference proteome
  • Steroid biosynthesis
Proteins
Displaying 1 entry
UniProt Protein Name
Q6GUR1
  • CYPIA1
  • Cytochrome P450 form 6
  • Cytochrome P450-C
  • Cytochrome P450-P1
  • Hydroperoxy icosatetraenoate dehydratase
Annotation information from UniProt.
Gene Ontology (GO)
Displaying all 2 entries
GO Term Evidence Code PMID
hormone biosynthetic process
progesterone metabolic process
GO Hierarchy
Displaying all 5 entries
GO Term Evidence Code PMID
steroid 17-alpha-monooxygenase activity
iron ion binding
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
17-alpha-hydroxyprogesterone aldolase activity
heme binding
GO Hierarchy
Gene Ontology information from NCBI Gene and UniProt.
KEGG BRITE Database
Orthology
K07408
Name
cytochrome P450 family 1 subfamily A1 [EC:1.14.14.1]
References
Rhea

RHEA:55556

a hydroperoxyeicosatetraenoate
an oxoeicosatetraenoate + H2O
Enzyme
PMID

RHEA:37943

(12R)-hydroperoxy-(5Z,8Z,10E,14Z)-eicosatetraenoate
H2O + 12-oxo-(5Z,8Z,10E,14Z)-eicosatetraenoate
Enzyme
PMID

RHEA:37927

(8S)-hydroperoxy-(5Z,9E,11Z,14Z)-eicosatetraenoate
H2O + 8-oxo-(5Z,9E,11Z,14Z)-eicosatetraenoate
Enzyme
PMID

RHEA:48636

(15S)-hydroperoxy-(5Z,8Z,11Z,13E)-eicosatetraenoate
H2O + 15-oxo-(5Z,8Z,11Z,13E)-eicosatetraenoate
Enzyme
PMID

RHEA:37935

(8R)-hydroperoxy-(5Z,9E,11Z,14Z)-eicosatetraenoate
H2O + 8-oxo-(5Z,9E,11Z,14Z)-eicosatetraenoate
Enzyme
PMID

RHEA:37947

(12S)-hydroperoxy-(5Z,8Z,10E,14Z)-eicosatetraenoate
H2O + 12-oxo-(5Z,8Z,10E,14Z)-eicosatetraenoate
Enzyme
PMID

RHEA:17149

an organic molecule + O2
H2O + H+ + an alcohol
Enzyme
PMID
Ortholog
Displaying entries 11 - 20 of 88 in total
Species Gene ID Alliance of Genome Resources Orthologous MAtrix
109308858 CROPO15695
109308859 CROPO15690
113442289 PSETE14701
113442331 PSETE14702
664714 MELGA02987
103823194 SERCA20151
100080942 ORNAN22942
100927711 SARHA17565
100393083 CALJA01850
105600061 CERAT43868
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: August 19, 2024