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Guidelines

MIRAGE

sulfatase modifying factor 2

Summary

Gene Symbol

Sumf2

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

67902

PubChem

67902

Alliance of Genome Resources

MGI:1915152

Annotation

Keyword

Calcium
Disulfide bond
Endoplasmic reticulum
Glycoprotein
Metal-binding
Reference proteome
Signal

Proteins

Displaying 1 entry
UniProt	Protein Name
Q8BPG6	Sulfatase-modifying factor 2

Annotation information from UniProt.

Gene Ontology (GO)

Displaying 1 entry
GO Term	Evidence Code	PMID
negative regulation of post-translational protein modification	ISO	15962010

GO Hierarchy

biological process

biological regulation [inference]

regulation of biological process [inference]

regulation of metabolic process [inference]

negative regulation of metabolic process [inference]

negative regulation of macromolecule metabolic process [inference]

negative regulation of protein metabolic process [inference]

negative regulation of protein modification process [inference]

negative regulation of post-translational protein modification

negative regulation of nitrogen compound metabolic process [inference]

negative regulation of protein metabolic process [inference]

negative regulation of protein modification process [inference]

negative regulation of post-translational protein modification

regulation of nitrogen compound metabolic process [inference]

negative regulation of nitrogen compound metabolic process [inference]

negative regulation of protein metabolic process [inference]

negative regulation of protein modification process [inference]

negative regulation of post-translational protein modification

regulation of protein metabolic process [inference]

regulation of protein modification process [inference]

negative regulation of protein modification process [inference]

negative regulation of post-translational protein modification

regulation of post-translational protein modification [inference]

negative regulation of post-translational protein modification

negative regulation of protein metabolic process [inference]

negative regulation of protein modification process [inference]

negative regulation of post-translational protein modification

regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule metabolic process [inference]

negative regulation of protein metabolic process [inference]

negative regulation of protein modification process [inference]

negative regulation of post-translational protein modification

regulation of protein metabolic process [inference]

regulation of protein modification process [inference]

negative regulation of protein modification process [inference]

negative regulation of post-translational protein modification

regulation of post-translational protein modification [inference]

negative regulation of post-translational protein modification

negative regulation of protein metabolic process [inference]

negative regulation of protein modification process [inference]

negative regulation of post-translational protein modification

regulation of primary metabolic process [inference]

regulation of protein metabolic process [inference]

regulation of protein modification process [inference]

negative regulation of protein modification process [inference]

negative regulation of post-translational protein modification

regulation of post-translational protein modification [inference]

negative regulation of post-translational protein modification

negative regulation of protein metabolic process [inference]

negative regulation of protein modification process [inference]

negative regulation of post-translational protein modification

negative regulation of biological process [inference]

negative regulation of metabolic process [inference]

negative regulation of macromolecule metabolic process [inference]

negative regulation of protein metabolic process [inference]

negative regulation of protein modification process [inference]

negative regulation of post-translational protein modification

negative regulation of nitrogen compound metabolic process [inference]

negative regulation of protein metabolic process [inference]

negative regulation of protein modification process [inference]

negative regulation of post-translational protein modification

Displaying **all 3** entries
GO Term	Evidence Code	PMID
endoplasmic reticulum	ISO
endoplasmic reticulum	IBA
endoplasmic reticulum lumen	IDA	15962010

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane-enclosed lumen [inference]

organelle lumen [inference]

intracellular organelle lumen [inference]

endoplasmic reticulum lumen

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

Displaying **all 5** entries
GO Term	Evidence Code	PMID
enzyme inhibitor activity	ISO	15962010
protein binding	IPI	15962010
identical protein binding	ISO
identical protein binding	IPI	15962010
metal ion binding	IEA

GO Hierarchy

molecular function

binding [inference]

protein binding

identical protein binding

ion binding [inference]

cation binding [inference]

metal ion binding

molecular function regulator activity [inference]

enzyme regulator activity [inference]

enzyme inhibitor activity

molecular function inhibitor activity [inference]

enzyme inhibitor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

sulfatase modifying factor

Functional Category

E: Amino acid transport and metabolism
H: Coenzyme transport and metabolism
J: Translation, ribosomal structure and biogenesis

Displaying **all 3** entries
InterPro
C-type lectin fold
Sulfatase-modifying factor enzyme superfamily
Sulfatase-modifying factor enzyme

Ortholog

Displaying entries **1 - 10** of 61 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Homo sapiens	25870	Xenbase:XB-GENE-5815462	HUMAN89080
Xenopus tropicalis	67902	Xenbase:XB-GENE-5815462
Rattus norvegicus	360800		RATNO05953
Danio rerio	449807		DANRE20607
Canis lupus familiaris	479701		CANLF16101
Bos taurus	509497		BOVIN20676
Pan troglodytes	742768		PANTR40317
Monodelphis domestica	100011901		MONDO14383
Ornithorhynchus anatinus	100088273		ORNAN09233
Pongo abelii	100172116		PONAB00212

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GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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GlyCosmos Portal v4.4.0

Last updated: December 8, 2025