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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
serine (or cysteine) peptidase inhibitor, clade I, member 2
Summary
- Gene Symbol
-
- Serpini2
- Organism
- Mus musculus (house mouse)
Annotation
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| negative regulation of endopeptidase activity | ||
| negative regulation of peptidase activity |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| collagen-containing extracellular matrix | ||
| extracellular space |
| GO Term | Evidence Code | PMID |
|---|---|---|
| serine-type endopeptidase inhibitor activity |
GO Hierarchy
OrthoDB (Group)
- Group level
- Rodentia
- Group Name
- serpin I2
- Functional Category
-
- C: Energy production and conversion
- O: Posttranslational modification, protein turnover, chaperones
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| serine-type endopeptidase inhibitor activity |
| InterPro |
|---|
| Serpin domain |
| Serpin family |
| Serpin superfamily, domain 1 |
| Serpin superfamily, domain 2 |
| Serpin superfamily |
| Serpin, conserved site |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050831 | familial encephalopathy with neuroserpin inclusion bodies | |
| DOID:0060479 | Shwachman-Diamond syndrome | |
| DOID:13372 | alpha 1-antitrypsin deficiency |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 5276 | HGNC:8945 | HUMAN73279 | ||
| 36163 | FB:FBgn0033574 | |||
| 43642 | FB:FBgn0039795 | |||
| 45908 | FB:FBgn0002930 | |||
| 49805 | FB:FBgn0265137 | |||
| 171149 | 10116_1:00110f | RGD:619897 | RATNO23834 | |
| 178585 | WB:WBGene00005642 | |||
| 178586 | WB:WBGene00005643 | |||
| 178672 | WB:WBGene00005644 | |||
| 179125 | WB:WBGene00005647 |
