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leucine rich repeat transmembrane neuronal 1

Summary

Gene Symbol

Lrrtm1

Organism

Rattus norvegicus (Norway rat)

External Links

NCBI Gene

679668

PubChem

679668

Alliance of Genome Resources

RGD:1585921

Annotation

Keyword

Cell membrane
Glycoprotein
Leucine-rich repeat
Postsynaptic cell membrane
Reference proteome
Repeat
Signal
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
D4A6D8

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 14 in total

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GO Term	Evidence Code	PMID
negative regulation of receptor internalization	ISO
locomotory behavior	ISO
receptor internalization	ISO
protein localization to synapse	ISO
exploration behavior	ISO

GO Hierarchy

biological process

cellular process [inference]

vesicle-mediated transport [inference]

endocytosis [inference]

receptor-mediated endocytosis [inference]

receptor internalization

cellular localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to cell junction [inference]

protein localization to synapse

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cell junction organization [inference]

synapse organization

multicellular organismal process [inference]

behavior [inference]

localization [inference]

macromolecule localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to cell junction [inference]

protein localization to synapse

establishment of localization [inference]

transport [inference]

vesicle-mediated transport [inference]

endocytosis [inference]

receptor-mediated endocytosis [inference]

receptor internalization

import into cell [inference]

endocytosis [inference]

receptor-mediated endocytosis [inference]

receptor internalization

establishment of localization in cell

cellular localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to cell junction [inference]

protein localization to synapse

biological regulation [inference]

regulation of biological process [inference]

regulation of signaling [inference]

positive regulation of signaling [inference]

positive regulation of synaptic transmission [inference]

long-term synaptic potentiation

regulation of trans-synaptic signaling [inference]

modulation of chemical synaptic transmission [inference]

regulation of synaptic plasticity [inference]

long-term synaptic potentiation

positive regulation of synaptic transmission [inference]

long-term synaptic potentiation

regulation of localization [inference]

regulation of transport [inference]

negative regulation of transport [inference]

negative regulation of endocytosis [inference]

negative regulation of receptor-mediated endocytosis [inference]

negative regulation of receptor internalization

regulation of vesicle-mediated transport [inference]

regulation of endocytosis [inference]

negative regulation of endocytosis [inference]

negative regulation of receptor-mediated endocytosis [inference]

negative regulation of receptor internalization

regulation of receptor-mediated endocytosis [inference]

regulation of receptor internalization [inference]

negative regulation of receptor internalization

negative regulation of receptor-mediated endocytosis [inference]

negative regulation of receptor internalization

positive regulation of biological process [inference]

positive regulation of signaling [inference]

positive regulation of synaptic transmission [inference]

long-term synaptic potentiation

positive regulation of cellular process [inference]

positive regulation of cell communication [inference]

positive regulation of synaptic transmission [inference]

long-term synaptic potentiation

positive regulation of cellular component biogenesis [inference]

positive regulation of cell junction assembly [inference]

positive regulation of synapse assembly

positive regulation of cellular component organization [inference]

positive regulation of cell junction assembly [inference]

positive regulation of synapse assembly

positive regulation of developmental process [inference]

positive regulation of nervous system development [inference]

positive regulation of synapse assembly

positive regulation of multicellular organismal process [inference]

positive regulation of nervous system development [inference]

positive regulation of synapse assembly

negative regulation of biological process [inference]

negative regulation of cellular process [inference]

negative regulation of cellular component organization [inference]

negative regulation of endocytosis [inference]

negative regulation of receptor-mediated endocytosis [inference]

negative regulation of receptor internalization

negative regulation of transport [inference]

negative regulation of endocytosis [inference]

negative regulation of receptor-mediated endocytosis [inference]

negative regulation of receptor internalization

regulation of developmental process [inference]

positive regulation of developmental process [inference]

positive regulation of nervous system development [inference]

positive regulation of synapse assembly

regulation of multicellular organismal development [inference]

regulation of nervous system development [inference]

positive regulation of nervous system development [inference]

positive regulation of synapse assembly

regulation of cellular process [inference]

regulation of cell communication [inference]

positive regulation of cell communication [inference]

positive regulation of synaptic transmission [inference]

long-term synaptic potentiation

regulation of trans-synaptic signaling [inference]

modulation of chemical synaptic transmission [inference]

regulation of synaptic plasticity [inference]

long-term synaptic potentiation

positive regulation of synaptic transmission [inference]

long-term synaptic potentiation

regulation of cellular component biogenesis [inference]

positive regulation of cellular component biogenesis [inference]

positive regulation of cell junction assembly [inference]

positive regulation of synapse assembly

regulation of cell junction assembly [inference]

regulation of synapse assembly [inference]

positive regulation of synapse assembly

regulation of excitatory synapse assembly [inference]

regulation of postsynaptic density assembly

regulation of presynapse assembly

positive regulation of cell junction assembly [inference]

positive regulation of synapse assembly

regulation of organelle assembly [inference]

regulation of postsynaptic specialization assembly [inference]

regulation of postsynaptic density assembly

positive regulation of cellular process [inference]

positive regulation of cell communication [inference]

positive regulation of synaptic transmission [inference]

long-term synaptic potentiation

positive regulation of cellular component biogenesis [inference]

positive regulation of cell junction assembly [inference]

positive regulation of synapse assembly

positive regulation of cellular component organization [inference]

positive regulation of cell junction assembly [inference]

positive regulation of synapse assembly

negative regulation of cellular process [inference]

negative regulation of cellular component organization [inference]

negative regulation of endocytosis [inference]

negative regulation of receptor-mediated endocytosis [inference]

negative regulation of receptor internalization

regulation of cellular component organization [inference]

regulation of endocytosis [inference]

negative regulation of endocytosis [inference]

negative regulation of receptor-mediated endocytosis [inference]

negative regulation of receptor internalization

regulation of receptor-mediated endocytosis [inference]

regulation of receptor internalization [inference]

negative regulation of receptor internalization

negative regulation of receptor-mediated endocytosis [inference]

negative regulation of receptor internalization

regulation of organelle organization [inference]

regulation of organelle assembly [inference]

regulation of postsynaptic specialization assembly [inference]

regulation of postsynaptic density assembly

regulation of postsynaptic density organization [inference]

regulation of postsynaptic density assembly

regulation of synapse organization [inference]

regulation of synapse assembly [inference]

positive regulation of synapse assembly

regulation of excitatory synapse assembly [inference]

regulation of postsynaptic density assembly

regulation of presynapse assembly

regulation of presynapse organization [inference]

regulation of presynapse assembly

regulation of postsynapse organization [inference]

regulation of postsynaptic density organization [inference]

regulation of postsynaptic density assembly

negative regulation of cellular component organization [inference]

negative regulation of endocytosis [inference]

negative regulation of receptor-mediated endocytosis [inference]

negative regulation of receptor internalization

positive regulation of cellular component organization [inference]

positive regulation of cell junction assembly [inference]

positive regulation of synapse assembly

regulation of cell junction assembly [inference]

regulation of synapse assembly [inference]

positive regulation of synapse assembly

regulation of excitatory synapse assembly [inference]

regulation of postsynaptic density assembly

regulation of presynapse assembly

positive regulation of cell junction assembly [inference]

positive regulation of synapse assembly

regulation of vesicle-mediated transport [inference]

regulation of endocytosis [inference]

negative regulation of endocytosis [inference]

negative regulation of receptor-mediated endocytosis [inference]

negative regulation of receptor internalization

regulation of receptor-mediated endocytosis [inference]

regulation of receptor internalization [inference]

negative regulation of receptor internalization

negative regulation of receptor-mediated endocytosis [inference]

negative regulation of receptor internalization

regulation of multicellular organismal process [inference]

positive regulation of multicellular organismal process [inference]

positive regulation of nervous system development [inference]

positive regulation of synapse assembly

regulation of multicellular organismal development [inference]

regulation of nervous system development [inference]

positive regulation of nervous system development [inference]

positive regulation of synapse assembly

regulation of biological quality [inference]

regulation of synaptic plasticity [inference]

long-term synaptic potentiation

Displaying entries **1 - 5** of 13 in total

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GO Term	Evidence Code	PMID
extracellular space	IBA
endoplasmic reticulum	ISO
cell surface	ISO
axon	ISO
growth cone	ISO

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

plasma membrane region [inference]

synaptic membrane [inference]

cell junction [inference]

synapse [inference]

external encapsulating structure [inference]

extracellular matrix

site of polarized growth [inference]

growth cone

cell projection [inference]

plasma membrane bounded cell projection [inference]

neuron projection [inference]

axon

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Leucine-rich repeat-containing protein

Functional Category

K: Transcription
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 3** entries
InterPro
Leucine-rich repeat domain superfamily
Leucine-rich repeat, typical subtype
Leucine-rich repeat

Ortholog

Displaying entries **41 - 50** of 92 in total

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Species	Gene ID	Orthologous MAtrix
Astyanax mexicanus	103046915	ASTMX16604
Poecilia formosa	103137874	POEFO06057
Callorhinchus milii	103190462	CALMI43764
Chlorocebus sabaeus	103219979	CHLSB04156
Carlito syrichta	103250288	CARSF14371
Cynoglossus semilaevis	103383805	CYNSE30212
Poecilia reticulata	103467387	POERE16378
Nannospalax galili	103749433	NANGA09524
Serinus canaria	103823104	SERCA20055
Rhinopithecus roxellana	104665165	RHIRO32873