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MIRAGE
syntaxin binding protein 1
Summary
- Gene Symbol
-
- STXBP1
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Alternative splicing
- Cytoplasm
- Disease variant
- Epilepsy
- Intellectual disability
- Membrane
- Phosphoprotein
- Protein transport
- Reference proteome
- Proteins
| UniProt | Protein Name |
|---|---|
| P61764 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| platelet degranulation | ||
| developmental process involved in reproduction | ||
| intracellular protein transport | ||
| vesicle docking involved in exocytosis | ||
| vesicle docking involved in exocytosis |
GO Hierarchy
biological process
cellular process [inference]
localization [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of signaling [inference]
regulation of localization [inference]
positive regulation of biological process [inference]
regulation of cellular process [inference]
regulation of cell communication [inference]
positive regulation of cellular process [inference]
regulation of cellular component organization [inference]
regulation of vesicle-mediated transport [inference]
regulation of secretion by cell [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| parallel fiber to Purkinje cell synapse | ||
| postsynapse | ||
| presynaptic active zone cytoplasmic component | ||
| extrinsic component of presynaptic membrane | ||
| glutamatergic synapse |
| GO Term | Evidence Code | PMID |
|---|---|---|
| syntaxin-1 binding | ||
| protein kinase binding | ||
| protein domain specific binding | ||
| syntaxin binding | ||
| identical protein binding |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- syntaxin binding
- Functional Category
-
- E: Amino acid transport and metabolism
- O: Posttranslational modification, protein turnover, chaperones
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| syntaxin-1 binding |
| vesicle docking involved in exocytosis |
| InterPro |
|---|
| Sec1-like protein |
| Sec1-like superfamily |
| Sec1-like, domain 1 |
| Sec1-like, domain 2 |
| Sec1-like, domain 3a |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050562 | West syndrome | |
| DOID:0080436 | developmental and epileptic encephalopathy 4 |
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 6812 | Xenbase:XB-GENE-945143 | ||
| 6813 | SGD:S000002571 | ||
| 20910 | Xenbase:XB-GENE-945143 | MOUSE34476 | |
| 25558 | RATNO27500 | ||
| 282378 | BOVIN03174 | ||
| 464750 | PANTR44874 | ||
| 574003 | DANRE21539 | ||
| 609241 | CANLF19428 | ||
| 707185 | MACMU13227 | ||
| 751993 | TAEGU06794 |
