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MIRAGE
calcium voltage-gated channel subunit alpha1 S
Summary
- Gene Symbol
-
- Cacna1s
- Organism
- Rattus norvegicus (Norway rat)
Annotation
- Keyword
-
- Alternative splicing
- Calcium channel
- Calmodulin-binding
- Cell membrane
- Disulfide bond
- Glycoprotein
- Metal-binding
- Phosphoprotein
- Reference proteome
- Repeat
- Transmembrane helix
- Voltage-gated channel
- Proteins
| UniProt | Protein Name |
|---|---|
| Q02485 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| release of sequestered calcium ion into cytosol | ||
| endoplasmic reticulum organization | ||
| muscle contraction | ||
| response to caloric restriction | ||
| muscle cell development |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| I band | ||
| L-type voltage-gated calcium channel complex | ||
| cytoplasm | ||
| plasma membrane | ||
| sarcolemma |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| voltage-gated calcium channel activity | ||
| metal ion binding | ||
| high voltage-gated calcium channel activity | ||
| calmodulin binding | ||
| molecular function activator activity |
GO Hierarchy
Alliance of Genome Resources
- Expression
| Location | References |
|---|---|
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0060173 | Timothy syndrome | |
| DOID:0081350 | congenital myopathy 18 | |
| DOID:11723 | Duchenne muscular dystrophy | |
| DOID:14452 | hypokalemic periodic paralysis | |
| DOID:8545 | malignant hyperthermia |
