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basigin (Ok blood group)

Summary

Gene Symbol

Organism

Homo sapiens (human)

External Links

NCBI Gene

682

PubChem

682

Alliance of Genome Resources

HGNC:1116

Annotation

Keyword

3D-structure
Alternative promoter usage
Alternative splicing
Angiogenesis
Blood group antigen
Cell membrane
Cell projection
Direct protein sequencing
Disulfide bond
Endoplasmic reticulum
Endosome
Glycoprotein
Host cell receptor for virus entry
Host-virus interaction
Immunoglobulin domain
Mannose-binding
Phosphoprotein
Reference proteome
Signal
Transmembrane helix

Proteins

Displaying **all 2** entries
UniProt	Protein Name
Q54A51
P35613	5F7 Collagenase stimulatory factor Extracellular matrix metalloproteinase inducer Hepatoma-associated antigen Leukocyte activation antigen M6 OK blood group antigen Tumor cell-derived collagenase stimulatory factor

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **16 - 20** of 26 in total

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GO Term	Evidence Code	PMID
positive regulation of viral entry into host cell	IMP	11353871 15688292
response to mercury ion	IEA
decidualization	IEA
viral entry into host cell	IEA
response to cAMP	IEA

GO Hierarchy

biological process

immune system process [inference]

leukocyte migration [inference]

leukocyte chemotaxis [inference]

granulocyte chemotaxis [inference]

neutrophil chemotaxis

myeloid leukocyte migration [inference]

granulocyte migration [inference]

granulocyte chemotaxis [inference]

neutrophil chemotaxis

neutrophil migration [inference]

neutrophil chemotaxis

cellular process [inference]

cell adhesion [inference]

cell-cell adhesion [inference]

cell-cell adhesion via plasma-membrane adhesion molecules [inference]

homophilic cell adhesion via plasma membrane adhesion molecules

signal transduction [inference]

cell surface receptor signaling pathway

cell recognition [inference]

neuron recognition [inference]

dendrite self-avoidance

cell motility [inference]

cell migration [inference]

leukocyte migration [inference]

leukocyte chemotaxis [inference]

granulocyte chemotaxis [inference]

neutrophil chemotaxis

myeloid leukocyte migration [inference]

granulocyte migration [inference]

granulocyte chemotaxis [inference]

neutrophil chemotaxis

neutrophil migration [inference]

neutrophil chemotaxis

cell chemotaxis [inference]

leukocyte chemotaxis [inference]

granulocyte chemotaxis [inference]

neutrophil chemotaxis

cellular localization [inference]

localization within membrane [inference]

protein localization to membrane [inference]

protein localization to plasma membrane

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to membrane [inference]

protein localization to plasma membrane

protein localization to cell periphery [inference]

protein localization to plasma membrane

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cell projection organization [inference]

plasma membrane bounded cell projection organization [inference]

neuron projection development [inference]

neuron projection guidance [inference]

axon guidance

reproductive process [inference]

developmental process involved in reproduction [inference]

decidualization

embryo implantation

multicellular organismal process [inference]

photoreceptor cell maintenance

developmental process [inference]

developmental process involved in reproduction [inference]

decidualization

anatomical structure morphogenesis [inference]

animal organ morphogenesis [inference]

odontogenesis [inference]

odontogenesis of dentin-containing tooth

tube morphogenesis [inference]

epithelial tube morphogenesis [inference]

endothelial tube morphogenesis

tissue morphogenesis [inference]

morphogenesis of an epithelium [inference]

morphogenesis of an endothelium [inference]

endothelial tube morphogenesis

epithelial tube morphogenesis [inference]

endothelial tube morphogenesis

anatomical structure formation involved in morphogenesis [inference]

angiogenesis

anatomical structure development [inference]

neural retina development

tissue development [inference]

decidualization

locomotion [inference]

taxis [inference]

chemotaxis [inference]

cell chemotaxis [inference]

leukocyte chemotaxis [inference]

granulocyte chemotaxis [inference]

neutrophil chemotaxis

biological process involved in interspecies interaction between organisms [inference]

biological process involved in symbiotic interaction [inference]

biological process involved in interaction with host [inference]

movement in host [inference]

entry into host [inference]

viral entry into host cell

response to stimulus [inference]

response to endogenous stimulus [inference]

response to hormone [inference]

response to peptide hormone

response to chemical [inference]

response to organic substance [inference]

response to hormone [inference]

response to peptide hormone

response to organonitrogen compound [inference]

response to purine-containing compound [inference]

response to cAMP

response to peptide [inference]

response to peptide hormone

response to organic cyclic compound [inference]

response to purine-containing compound [inference]

response to cAMP

response to organophosphorus [inference]

response to cAMP

response to inorganic substance [inference]

response to metal ion [inference]

response to mercury ion

response to nitrogen compound [inference]

response to organonitrogen compound [inference]

response to purine-containing compound [inference]

response to cAMP

response to peptide [inference]

response to peptide hormone

response to oxygen-containing compound [inference]

response to cAMP

response to peptide [inference]

response to peptide hormone

localization [inference]

macromolecule localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to membrane [inference]

protein localization to plasma membrane

protein localization to cell periphery [inference]

protein localization to plasma membrane

cellular localization [inference]

localization within membrane [inference]

protein localization to membrane [inference]

protein localization to plasma membrane

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to membrane [inference]

protein localization to plasma membrane

protein localization to cell periphery [inference]

protein localization to plasma membrane

biological regulation [inference]

regulation of biological process [inference]

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

positive regulation of cytokine production [inference]

regulation of vascular endothelial growth factor production [inference]

positive regulation of vascular endothelial growth factor production

regulation of interleukin-6 production [inference]

positive regulation of interleukin-6 production

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

regulation of cellular metabolic process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

positive regulation of cytokine production [inference]

regulation of vascular endothelial growth factor production [inference]

positive regulation of vascular endothelial growth factor production

regulation of interleukin-6 production [inference]

positive regulation of interleukin-6 production

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

positive regulation of cytokine production [inference]

regulation of vascular endothelial growth factor production [inference]

positive regulation of vascular endothelial growth factor production

regulation of interleukin-6 production [inference]

positive regulation of interleukin-6 production

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

regulation of localization [inference]

regulation of transport [inference]

regulation of secretion [inference]

positive regulation of secretion [inference]

positive regulation of secretion by cell [inference]

positive regulation of protein secretion [inference]

positive regulation of matrix metallopeptidase secretion

regulation of secretion by cell [inference]

regulation of protein secretion [inference]

positive regulation of protein secretion [inference]

positive regulation of matrix metallopeptidase secretion

regulation of matrix metallopeptidase secretion [inference]

positive regulation of matrix metallopeptidase secretion

positive regulation of secretion by cell [inference]

positive regulation of protein secretion [inference]

positive regulation of matrix metallopeptidase secretion

positive regulation of transport [inference]

positive regulation of secretion [inference]

positive regulation of secretion by cell [inference]

positive regulation of protein secretion [inference]

positive regulation of matrix metallopeptidase secretion

positive regulation of protein transport [inference]

positive regulation of protein secretion [inference]

positive regulation of matrix metallopeptidase secretion

regulation of protein transport [inference]

regulation of protein secretion [inference]

positive regulation of protein secretion [inference]

positive regulation of matrix metallopeptidase secretion

regulation of matrix metallopeptidase secretion [inference]

positive regulation of matrix metallopeptidase secretion

positive regulation of protein transport [inference]

positive regulation of protein secretion [inference]

positive regulation of matrix metallopeptidase secretion

regulation of cellular localization [inference]

regulation of protein localization [inference]

regulation of establishment of protein localization [inference]

regulation of protein transport [inference]

regulation of protein secretion [inference]

positive regulation of protein secretion [inference]

positive regulation of matrix metallopeptidase secretion

regulation of matrix metallopeptidase secretion [inference]

positive regulation of matrix metallopeptidase secretion

positive regulation of protein transport [inference]

positive regulation of protein secretion [inference]

positive regulation of matrix metallopeptidase secretion

positive regulation of establishment of protein localization [inference]

positive regulation of protein transport [inference]

positive regulation of protein secretion [inference]

positive regulation of matrix metallopeptidase secretion

positive regulation of protein localization [inference]

positive regulation of establishment of protein localization [inference]

positive regulation of protein transport [inference]

positive regulation of protein secretion [inference]

positive regulation of matrix metallopeptidase secretion

regulation of locomotion [inference]

positive regulation of locomotion [inference]

positive regulation of cell motility [inference]

positive regulation of cell migration [inference]

positive regulation of epithelial cell migration [inference]

positive regulation of endothelial cell migration

regulation of cell motility [inference]

regulation of cell migration [inference]

regulation of epithelial cell migration [inference]

regulation of endothelial cell migration [inference]

positive regulation of endothelial cell migration

positive regulation of epithelial cell migration [inference]

positive regulation of endothelial cell migration

positive regulation of cell migration [inference]

positive regulation of epithelial cell migration [inference]

positive regulation of endothelial cell migration

positive regulation of cell motility [inference]

positive regulation of cell migration [inference]

positive regulation of epithelial cell migration [inference]

positive regulation of endothelial cell migration

regulation of biological process involved in symbiotic interaction [inference]

modulation by symbiont of entry into host [inference]

regulation of viral entry into host cell [inference]

positive regulation of viral entry into host cell

positive regulation by symbiont of entry into host [inference]

positive regulation of viral entry into host cell

positive regulation of biological process [inference]

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of locomotion [inference]

positive regulation of cell motility [inference]

positive regulation of cell migration [inference]

positive regulation of epithelial cell migration [inference]

positive regulation of endothelial cell migration

positive regulation of cellular process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of secretion by cell [inference]

positive regulation of protein secretion [inference]

positive regulation of matrix metallopeptidase secretion

positive regulation of protein localization [inference]

positive regulation of establishment of protein localization [inference]

positive regulation of protein transport [inference]

positive regulation of protein secretion [inference]

positive regulation of matrix metallopeptidase secretion

positive regulation of cell motility [inference]

positive regulation of cell migration [inference]

positive regulation of epithelial cell migration [inference]

positive regulation of endothelial cell migration

positive regulation of viral process [inference]

positive regulation of viral life cycle [inference]

positive regulation of viral entry into host cell

positive regulation of transport [inference]

positive regulation of secretion [inference]

positive regulation of secretion by cell [inference]

positive regulation of protein secretion [inference]

positive regulation of matrix metallopeptidase secretion

positive regulation of protein transport [inference]

positive regulation of protein secretion [inference]

positive regulation of matrix metallopeptidase secretion

positive regulation of multicellular organismal process [inference]

positive regulation of cytokine production [inference]

positive regulation by symbiont of entry into host [inference]

positive regulation of viral entry into host cell

regulation of viral process [inference]

positive regulation of viral process [inference]

positive regulation of viral life cycle [inference]

positive regulation of viral entry into host cell

regulation of viral life cycle [inference]

regulation of viral entry into host cell [inference]

positive regulation of viral entry into host cell

positive regulation of viral life cycle [inference]

positive regulation of viral entry into host cell

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway

regulation of cellular metabolic process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

positive regulation of cytokine production [inference]

regulation of vascular endothelial growth factor production [inference]

positive regulation of vascular endothelial growth factor production

regulation of interleukin-6 production [inference]

positive regulation of interleukin-6 production

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cellular process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of secretion by cell [inference]

positive regulation of protein secretion [inference]

positive regulation of matrix metallopeptidase secretion

positive regulation of protein localization [inference]

positive regulation of establishment of protein localization [inference]

positive regulation of protein transport [inference]

positive regulation of protein secretion [inference]

positive regulation of matrix metallopeptidase secretion

positive regulation of cell motility [inference]

positive regulation of cell migration [inference]

positive regulation of epithelial cell migration [inference]

positive regulation of endothelial cell migration

regulation of cellular localization [inference]

regulation of protein localization [inference]

regulation of establishment of protein localization [inference]

regulation of protein transport [inference]

regulation of protein secretion [inference]

positive regulation of protein secretion [inference]

positive regulation of matrix metallopeptidase secretion

regulation of matrix metallopeptidase secretion [inference]

positive regulation of matrix metallopeptidase secretion

positive regulation of protein transport [inference]

positive regulation of protein secretion [inference]

positive regulation of matrix metallopeptidase secretion

positive regulation of establishment of protein localization [inference]

positive regulation of protein transport [inference]

positive regulation of protein secretion [inference]

positive regulation of matrix metallopeptidase secretion

positive regulation of protein localization [inference]

positive regulation of establishment of protein localization [inference]

positive regulation of protein transport [inference]

positive regulation of protein secretion [inference]

positive regulation of matrix metallopeptidase secretion

regulation of secretion by cell [inference]

regulation of protein secretion [inference]

positive regulation of protein secretion [inference]

positive regulation of matrix metallopeptidase secretion

regulation of matrix metallopeptidase secretion [inference]

positive regulation of matrix metallopeptidase secretion

positive regulation of secretion by cell [inference]

positive regulation of protein secretion [inference]

positive regulation of matrix metallopeptidase secretion

regulation of cell motility [inference]

regulation of cell migration [inference]

regulation of epithelial cell migration [inference]

regulation of endothelial cell migration [inference]

positive regulation of endothelial cell migration

positive regulation of epithelial cell migration [inference]

positive regulation of endothelial cell migration

positive regulation of cell migration [inference]

positive regulation of epithelial cell migration [inference]

positive regulation of endothelial cell migration

positive regulation of cell motility [inference]

positive regulation of cell migration [inference]

positive regulation of epithelial cell migration [inference]

positive regulation of endothelial cell migration

regulation of multicellular organismal process [inference]

regulation of cytokine production [inference]

positive regulation of cytokine production [inference]

regulation of vascular endothelial growth factor production [inference]

positive regulation of vascular endothelial growth factor production

regulation of interleukin-6 production [inference]

positive regulation of interleukin-6 production

regulation of epithelial cell migration [inference]

regulation of endothelial cell migration [inference]

positive regulation of endothelial cell migration

positive regulation of epithelial cell migration [inference]

positive regulation of endothelial cell migration

positive regulation of multicellular organismal process [inference]

positive regulation of cytokine production [inference]

Displaying entries **11 - 15** of 25 in total

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GO Term	Evidence Code	PMID
endoplasmic reticulum membrane	IEA
plasma membrane	ISS
plasma membrane	TAS
plasma membrane	IDA	11992541 15688292 15946952 25825981 26195724 29739904
plasma membrane	IBA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane

plasma membrane

sarcolemma

organelle membrane [inference]

endoplasmic reticulum membrane

vesicle membrane [inference]

cytoplasmic vesicle membrane [inference]

secretory granule membrane [inference]

acrosomal membrane

bounding membrane of organelle [inference]

Golgi membrane

secretory granule membrane [inference]

acrosomal membrane

plasma membrane region [inference]

basolateral plasma membrane

lateral plasma membrane

cell junction [inference]

anchoring junction [inference]

cell-substrate junction [inference]

focal adhesion

cell projection [inference]

plasma membrane bounded cell projection [inference]

neuron projection [inference]

axon

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome

pigment granule [inference]

melanosome

extracellular vesicle [inference]

extracellular exosome

intracellular membrane-bounded organelle

mitochondrion

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome

pigment granule [inference]

melanosome

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

intracellular organelle [inference]

intracellular membrane-bounded organelle

mitochondrion

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome

pigment granule [inference]

melanosome

extracellular organelle [inference]

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

Displaying entries **1 - 5** of 7 in total

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GO Term	Evidence Code	PMID
virus receptor activity	IMP	20147391
virus receptor activity	IEA
protein binding	IPI	11353871 11943775 15688292 15890777 15946952 17127621 17267690 21245143 22080952 24297912 25132548 25296023 25825981 25957687 26195724 28096331 28186186 28666119 29423001 30542156 32296183 33277466 33961781 34819669
mannose binding	IEA
signaling receptor activity	IDA	11688976 25957687

GO Hierarchy

molecular function

binding [inference]

protein binding

cell adhesion molecule binding [inference]

cadherin binding

cell adhesion mediator activity [inference]

cell-cell adhesion mediator activity

exogenous protein binding [inference]

virus receptor activity

carbohydrate binding [inference]

monosaccharide binding [inference]

mannose binding

small molecule binding [inference]

monosaccharide binding [inference]

mannose binding

molecular transducer activity [inference]

signaling receptor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

basigin

Functional Category

G: Carbohydrate transport and metabolism
M: Cell wall/membrane/envelope biogenesis
O: Posttranslational modification, protein turnover, chaperones

Displaying **all 3** entries
Gene Ontology
cell-cell adhesion mediator activity
dendrite self-avoidance
homophilic cell adhesion via plasma membrane adhesion molecules

Displaying **all 5** entries
InterPro
Immunoglobulin subtype 2
Immunoglobulin subtype
Immunoglobulin-like domain superfamily
Immunoglobulin-like domain
Immunoglobulin-like fold

Ortholog

Displaying entries **1 - 10** of 41 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Xenopus tropicalis	682	Xenbase:XB-GENE-5901795
Mus musculus	12215	Xenbase:XB-GENE-5901795	MOUSE02611
Drosophila melanogaster	20320	FB:FBgn0261822
Rattus norvegicus	25246	Xenbase:XB-GENE-5901795	RATNO39554
Drosophila melanogaster	27020	FB:FBgn0261822
Drosophila melanogaster	56064	FB:FBgn0261822
Danio rerio	189580	ZFIN:ZDB-GENE-030131-9638
Xenopus tropicalis	318841	Xenbase:XB-GENE-5901795
Macaca mulatta	721068		MACMU19418
Monodelphis domestica	100024705		MONDO17711

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

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Summary

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Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements