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shugoshin 2A

Summary

Gene Symbol

Sgo2a

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

68549

PubChem

68549

Alliance of Genome Resources

MGI:1098767

Annotation

Keyword

Cell division
Centromere
Chromosome
Chromosome partition
Coiled coil
Direct protein sequencing
Kinetochore
Meiosis
Nucleus
Phosphoprotein
Reference proteome

Proteins

Displaying 1 entry
UniProt	Protein Name
Q7TSY8	Shugoshin-2 Shugoshin-like 2

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 10 in total

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GO Term	Evidence Code	PMID
chromosome segregation	IEA
male meiotic nuclear division	IMP	18765791
female meiotic nuclear division	IMP	18765791
protein localization	IMP	18084284
meiotic sister chromatid cohesion involved in meiosis I	IMP	25533956

GO Hierarchy

biological process

cellular process [inference]

cell cycle process [inference]

chromosome segregation

sister chromatid cohesion [inference]

meiotic sister chromatid cohesion

centromeric sister chromatid cohesion [inference]

meiotic sister chromatid cohesion, centromeric

maintenance of sister chromatid cohesion [inference]

maintenance of meiotic sister chromatid cohesion [inference]

maintenance of meiotic sister chromatid cohesion, centromeric

meiotic cell cycle process [inference]

meiotic nuclear division [inference]

cellular process involved in reproduction in multicellular organism [inference]

cell division

cellular localization [inference]

cellular macromolecule localization [inference]

protein localization

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

organelle fission [inference]

nuclear division [inference]

meiotic nuclear division [inference]

chromosome organization [inference]

sister chromatid cohesion [inference]

meiotic sister chromatid cohesion

centromeric sister chromatid cohesion [inference]

meiotic sister chromatid cohesion, centromeric

reproductive process [inference]

cellular process involved in reproduction in multicellular organism [inference]

meiotic cell cycle process [inference]

meiotic nuclear division [inference]

localization [inference]

macromolecule localization [inference]

cellular macromolecule localization [inference]

protein localization

cellular localization [inference]

cellular macromolecule localization [inference]

protein localization

biological regulation [inference]

regulation of biological process [inference]

positive regulation of biological process [inference]

positive regulation of cellular process [inference]

positive regulation of cell cycle [inference]

positive regulation of cell cycle process [inference]

positive regulation of sister chromatid cohesion [inference]

positive regulation of maintenance of sister chromatid cohesion [inference]

positive regulation of maintenance of meiotic sister chromatid cohesion [inference]

positive regulation of maintenance of meiotic sister chromatid cohesion, centromeric

positive regulation of cellular component organization [inference]

positive regulation of organelle organization [inference]

positive regulation of chromosome organization [inference]

positive regulation of sister chromatid cohesion [inference]

positive regulation of maintenance of sister chromatid cohesion [inference]

positive regulation of maintenance of meiotic sister chromatid cohesion [inference]

positive regulation of maintenance of meiotic sister chromatid cohesion, centromeric

regulation of cellular process [inference]

positive regulation of cellular process [inference]

positive regulation of cell cycle [inference]

positive regulation of cell cycle process [inference]

positive regulation of sister chromatid cohesion [inference]

positive regulation of maintenance of sister chromatid cohesion [inference]

positive regulation of maintenance of meiotic sister chromatid cohesion [inference]

positive regulation of maintenance of meiotic sister chromatid cohesion, centromeric

positive regulation of cellular component organization [inference]

positive regulation of organelle organization [inference]

positive regulation of chromosome organization [inference]

positive regulation of sister chromatid cohesion [inference]

positive regulation of maintenance of sister chromatid cohesion [inference]

positive regulation of maintenance of meiotic sister chromatid cohesion [inference]

positive regulation of maintenance of meiotic sister chromatid cohesion, centromeric

regulation of cellular component organization [inference]

regulation of organelle organization [inference]

positive regulation of organelle organization [inference]

positive regulation of chromosome organization [inference]

positive regulation of sister chromatid cohesion [inference]

positive regulation of maintenance of sister chromatid cohesion [inference]

positive regulation of maintenance of meiotic sister chromatid cohesion [inference]

positive regulation of maintenance of meiotic sister chromatid cohesion, centromeric

regulation of chromosome organization [inference]

regulation of sister chromatid cohesion [inference]

regulation of maintenance of sister chromatid cohesion [inference]

positive regulation of maintenance of sister chromatid cohesion [inference]

positive regulation of maintenance of meiotic sister chromatid cohesion [inference]

positive regulation of maintenance of meiotic sister chromatid cohesion, centromeric

regulation of maintenance of meiotic sister chromatid cohesion [inference]

positive regulation of maintenance of meiotic sister chromatid cohesion [inference]

positive regulation of maintenance of meiotic sister chromatid cohesion, centromeric

regulation of maintenance of meiotic sister chromatid cohesion, centromeric [inference]

positive regulation of maintenance of meiotic sister chromatid cohesion, centromeric

positive regulation of sister chromatid cohesion [inference]

positive regulation of maintenance of sister chromatid cohesion [inference]

positive regulation of maintenance of meiotic sister chromatid cohesion [inference]

positive regulation of maintenance of meiotic sister chromatid cohesion, centromeric

regulation of centromeric sister chromatid cohesion [inference]

regulation of maintenance of meiotic sister chromatid cohesion, centromeric [inference]

positive regulation of maintenance of meiotic sister chromatid cohesion, centromeric

positive regulation of chromosome organization [inference]

positive regulation of sister chromatid cohesion [inference]

positive regulation of maintenance of sister chromatid cohesion [inference]

positive regulation of maintenance of meiotic sister chromatid cohesion [inference]

positive regulation of maintenance of meiotic sister chromatid cohesion, centromeric

positive regulation of cellular component organization [inference]

positive regulation of organelle organization [inference]

positive regulation of chromosome organization [inference]

positive regulation of sister chromatid cohesion [inference]

positive regulation of maintenance of sister chromatid cohesion [inference]

positive regulation of maintenance of meiotic sister chromatid cohesion [inference]

positive regulation of maintenance of meiotic sister chromatid cohesion, centromeric

regulation of cell cycle [inference]

regulation of cell cycle process [inference]

regulation of sister chromatid cohesion [inference]

regulation of maintenance of sister chromatid cohesion [inference]

positive regulation of maintenance of sister chromatid cohesion [inference]

positive regulation of maintenance of meiotic sister chromatid cohesion [inference]

positive regulation of maintenance of meiotic sister chromatid cohesion, centromeric

regulation of maintenance of meiotic sister chromatid cohesion [inference]

positive regulation of maintenance of meiotic sister chromatid cohesion [inference]

positive regulation of maintenance of meiotic sister chromatid cohesion, centromeric

regulation of maintenance of meiotic sister chromatid cohesion, centromeric [inference]

positive regulation of maintenance of meiotic sister chromatid cohesion, centromeric

positive regulation of sister chromatid cohesion [inference]

positive regulation of maintenance of sister chromatid cohesion [inference]

positive regulation of maintenance of meiotic sister chromatid cohesion [inference]

positive regulation of maintenance of meiotic sister chromatid cohesion, centromeric

regulation of centromeric sister chromatid cohesion [inference]

regulation of maintenance of meiotic sister chromatid cohesion, centromeric [inference]

positive regulation of maintenance of meiotic sister chromatid cohesion, centromeric

positive regulation of cell cycle process [inference]

positive regulation of sister chromatid cohesion [inference]

positive regulation of maintenance of sister chromatid cohesion [inference]

positive regulation of maintenance of meiotic sister chromatid cohesion [inference]

positive regulation of maintenance of meiotic sister chromatid cohesion, centromeric

positive regulation of cell cycle [inference]

positive regulation of cell cycle process [inference]

positive regulation of sister chromatid cohesion [inference]

positive regulation of maintenance of sister chromatid cohesion [inference]

positive regulation of maintenance of meiotic sister chromatid cohesion [inference]

positive regulation of maintenance of meiotic sister chromatid cohesion, centromeric

Displaying entries **1 - 5** of 9 in total

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GO Term	Evidence Code	PMID
chromosome, centromeric region	ISO
chromosome, centromeric region	IDA	17205076 18084284
kinetochore	IDA	18084284
kinetochore	IBA
condensed chromosome, centromeric region	IDA	18084284 18765791 19283064 25533956

GO Hierarchy

cellular component

protein-containing complex [inference]

cohesin complex [inference]

mitotic cohesin complex

cellular anatomical entity [inference]

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

non-membrane-bounded organelle [inference]

intracellular non-membrane-bounded organelle [inference]

kinetochore

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

intracellular non-membrane-bounded organelle [inference]

kinetochore

chromosomal region [inference]

chromosome, centromeric region

condensed chromosome, centromeric region

supramolecular complex [inference]

kinetochore

Displaying 1 entry
GO Term	Evidence Code	PMID
protein binding	IPI	21666598

GO Hierarchy

molecular function

binding [inference]

protein binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

shugoshin 2

Functional Category

C: Energy production and conversion
E: Amino acid transport and metabolism
T: Signal transduction mechanisms

Displaying **all 4** entries
Gene Ontology
cell cycle
cell division
chromosome segregation
meiotic sister chromatid cohesion

Displaying 1 entry
InterPro
Shugoshin 1/2

Ortholog

Displaying entries **1 - 10** of 37 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Danio rerio	68549	ZFIN:ZDB-GENE-081104-423
Homo sapiens	151246		HUMAN66285
Rattus norvegicus	316425		RATNO42577
Pan troglodytes	459862		PANTR29472
Canis lupus familiaris	478863		CANLF14101
Bos taurus	532412		BOVIN24537
Macaca mulatta	699688		MACMU06257
Equus caballus	100070958		HORSE13596
Callithrix jacchus	100390383		CALJA37142
Sus scrofa	100522763		PIGXX09756