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tachykinin receptor 1

Summary

Gene Symbol

TACR1

Organism

Homo sapiens (human)

External Links

NCBI Gene

6869

PubChem

6869

Alliance of Genome Resources

HGNC:11526

JoGo

TACR1

TogoVar

TACR1

Annotation

Keyword

3D-structure
Alternative splicing
Cell membrane
Disulfide bond
Endosome
G-protein coupled receptor
Glycoprotein
Palmitate
Proteomics identification
Reference proteome
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
P25103	NK-1 receptor Tachykinin receptor 1

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 40 in total

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GO Term	Evidence Code	PMID
aggressive behavior	IEA
positive regulation of leukocyte migration	IEA
angiotensin-mediated drinking behavior	IEA
inflammatory response	TAS	10854844
phospholipase C-activating G protein-coupled receptor signaling pathway	TAS	1657150

GO Hierarchy

biological process

cellular process [inference]

signal transduction [inference]

G protein-coupled receptor signaling pathway [inference]

reproductive process [inference]

multicellular organismal reproductive process [inference]

sperm ejaculation

multicellular organismal process [inference]

system process [inference]

muscle system process [inference]

muscle contraction [inference]

smooth muscle contraction [inference]

urinary tract smooth muscle contraction [inference]

urinary bladder smooth muscle contraction [inference]

smooth muscle contraction involved in micturition

circulatory system process [inference]

vascular process in circulatory system [inference]

regulation of vascular permeability [inference]

positive regulation of vascular permeability

blood vessel diameter maintenance [inference]

regulation of vasoconstriction [inference]

positive regulation of vasoconstriction

nervous system process [inference]

cognition [inference]

learning or memory [inference]

learning [inference]

memory [inference]

long-term memory

behavior [inference]

aggressive behavior

learning or memory [inference]

learning [inference]

memory [inference]

long-term memory

feeding behavior [inference]

eating behavior

drinking behavior [inference]

angiotensin-mediated drinking behavior

behavioral response to pain

response to stimulus [inference]

response to stress [inference]

defense response [inference]

inflammatory response

response to oxidative stress [inference]

response to reactive oxygen species [inference]

response to ozone

response to external stimulus [inference]

response to mechanical stimulus [inference]

response to auditory stimulus

response to abiotic stimulus [inference]

detection of abiotic stimulus

response to mechanical stimulus [inference]

response to auditory stimulus

response to electrical stimulus

response to endogenous stimulus [inference]

response to hormone [inference]

response to steroid hormone [inference]

response to progesterone

response to chemical [inference]

response to organic substance [inference]

response to hormone [inference]

response to steroid hormone [inference]

response to progesterone

response to organic cyclic compound [inference]

response to estradiol

response to steroid hormone [inference]

response to progesterone

response to lipid [inference]

response to estradiol

response to steroid hormone [inference]

response to progesterone

response to alcohol [inference]

response to ethanol

response to ketone [inference]

response to progesterone

response to inorganic substance [inference]

response to ozone

response to nicotine

response to oxygen-containing compound [inference]

response to reactive oxygen species [inference]

response to ozone

response to estradiol

response to alcohol [inference]

response to ethanol

response to ketone [inference]

response to progesterone

detection of stimulus [inference]

detection of abiotic stimulus

biological regulation [inference]

regulation of biological process [inference]

regulation of immune system process [inference]

positive regulation of immune system process [inference]

positive regulation of leukocyte migration

positive regulation of leukocyte activation [inference]

positive regulation of lymphocyte activation [inference]

positive regulation of lymphocyte proliferation

regulation of leukocyte migration [inference]

positive regulation of leukocyte migration

regulation of leukocyte activation [inference]

positive regulation of leukocyte activation [inference]

positive regulation of lymphocyte activation [inference]

positive regulation of lymphocyte proliferation

regulation of lymphocyte activation [inference]

regulation of lymphocyte proliferation [inference]

positive regulation of lymphocyte proliferation

positive regulation of lymphocyte activation [inference]

positive regulation of lymphocyte proliferation

regulation of signaling [inference]

positive regulation of signaling [inference]

positive regulation of hormone secretion

positive regulation of synaptic transmission [inference]

regulation of hormone secretion [inference]

positive regulation of hormone secretion

regulation of trans-synaptic signaling [inference]

modulation of chemical synaptic transmission [inference]

regulation of synaptic transmission, cholinergic [inference]

positive regulation of synaptic transmission, cholinergic

regulation of synaptic transmission, GABAergic [inference]

positive regulation of synaptic transmission, GABAergic

positive regulation of synaptic transmission [inference]

regulation of localization [inference]

regulation of transport [inference]

regulation of secretion [inference]

positive regulation of secretion [inference]

positive regulation of secretion by cell [inference]

positive regulation of hormone secretion

regulation of secretion by cell [inference]

regulation of hormone secretion [inference]

positive regulation of hormone secretion

positive regulation of secretion by cell [inference]

positive regulation of hormone secretion

positive regulation of transport [inference]

positive regulation of secretion [inference]

positive regulation of secretion by cell [inference]

positive regulation of hormone secretion

regulation of locomotion [inference]

positive regulation of locomotion [inference]

positive regulation of cell motility [inference]

positive regulation of cell migration [inference]

positive regulation of cilium-dependent cell motility [inference]

positive regulation of flagellated sperm motility

regulation of cell motility [inference]

regulation of cell migration [inference]

regulation of leukocyte migration [inference]

positive regulation of leukocyte migration

regulation of epithelial cell migration [inference]

positive regulation of epithelial cell migration

regulation of smooth muscle cell migration

positive regulation of cell migration [inference]

regulation of cilium-dependent cell motility [inference]

regulation of cilium movement involved in cell motility [inference]

regulation of flagellated sperm motility [inference]

positive regulation of flagellated sperm motility

positive regulation of cilium-dependent cell motility [inference]

positive regulation of flagellated sperm motility

positive regulation of cell motility [inference]

positive regulation of cell migration [inference]

positive regulation of cilium-dependent cell motility [inference]

positive regulation of flagellated sperm motility

positive regulation of biological process [inference]

positive regulation of immune system process [inference]

positive regulation of leukocyte migration

positive regulation of leukocyte activation [inference]

positive regulation of lymphocyte activation [inference]

positive regulation of lymphocyte proliferation

positive regulation of signaling [inference]

positive regulation of hormone secretion

positive regulation of synaptic transmission [inference]

positive regulation of locomotion [inference]

positive regulation of cell motility [inference]

positive regulation of cell migration [inference]

positive regulation of cilium-dependent cell motility [inference]

positive regulation of flagellated sperm motility

positive regulation of action potential

positive regulation of cellular process [inference]

positive regulation of cilium movement [inference]

positive regulation of flagellated sperm motility

positive regulation of cell population proliferation [inference]

positive regulation of epithelial cell proliferation

positive regulation of leukocyte proliferation [inference]

positive regulation of mononuclear cell proliferation [inference]

positive regulation of lymphocyte proliferation

positive regulation of cell communication [inference]

positive regulation of hormone secretion

positive regulation of synaptic transmission [inference]

positive regulation of cellular component biogenesis [inference]

positive regulation of actin filament bundle assembly [inference]

positive regulation of stress fiber assembly

positive regulation of cell activation [inference]

positive regulation of leukocyte activation [inference]

positive regulation of lymphocyte activation [inference]

positive regulation of lymphocyte proliferation

positive regulation of cellular component organization [inference]

positive regulation of organelle organization [inference]

positive regulation of cytoskeleton organization [inference]

positive regulation of actin filament bundle assembly [inference]

positive regulation of stress fiber assembly

positive regulation of supramolecular fiber organization [inference]

positive regulation of actin filament bundle assembly [inference]

positive regulation of stress fiber assembly

positive regulation of secretion by cell [inference]

positive regulation of hormone secretion

positive regulation of cell motility [inference]

positive regulation of cell migration [inference]

positive regulation of cilium-dependent cell motility [inference]

positive regulation of flagellated sperm motility

positive regulation of transport [inference]

positive regulation of secretion [inference]

positive regulation of secretion by cell [inference]

positive regulation of hormone secretion

positive regulation of multicellular organismal process [inference]

positive regulation of muscle contraction [inference]

positive regulation of smooth muscle contraction [inference]

positive regulation of uterine smooth muscle contraction

positive regulation of cell activation [inference]

positive regulation of leukocyte activation [inference]

positive regulation of lymphocyte activation [inference]

positive regulation of lymphocyte proliferation

positive regulation of reproductive process [inference]

positive regulation of flagellated sperm motility

regulation of cellular process [inference]

signal transduction [inference]

G protein-coupled receptor signaling pathway [inference]

regulation of cell communication [inference]

positive regulation of cell communication [inference]

positive regulation of hormone secretion

positive regulation of synaptic transmission [inference]

regulation of hormone secretion [inference]

positive regulation of hormone secretion

regulation of trans-synaptic signaling [inference]

modulation of chemical synaptic transmission [inference]

regulation of synaptic transmission, cholinergic [inference]

positive regulation of synaptic transmission, cholinergic

regulation of synaptic transmission, GABAergic [inference]

positive regulation of synaptic transmission, GABAergic

positive regulation of synaptic transmission [inference]

regulation of microtubule-based process [inference]

regulation of microtubule-based movement [inference]

regulation of cilium movement [inference]

positive regulation of cilium movement [inference]

positive regulation of flagellated sperm motility

regulation of cilium movement involved in cell motility [inference]

regulation of flagellated sperm motility [inference]

positive regulation of flagellated sperm motility

regulation of actin filament-based process [inference]

regulation of actin cytoskeleton organization [inference]

regulation of actomyosin structure organization [inference]

regulation of stress fiber assembly [inference]

positive regulation of stress fiber assembly

regulation of actin filament organization [inference]

regulation of actin filament bundle assembly [inference]

positive regulation of actin filament bundle assembly [inference]

positive regulation of stress fiber assembly

regulation of stress fiber assembly [inference]

positive regulation of stress fiber assembly

regulation of cell population proliferation [inference]

positive regulation of cell population proliferation [inference]

positive regulation of epithelial cell proliferation

positive regulation of leukocyte proliferation [inference]

positive regulation of mononuclear cell proliferation [inference]

positive regulation of lymphocyte proliferation

regulation of smooth muscle cell proliferation

regulation of epithelial cell proliferation [inference]

positive regulation of epithelial cell proliferation

regulation of leukocyte proliferation [inference]

regulation of mononuclear cell proliferation [inference]

positive regulation of mononuclear cell proliferation [inference]

positive regulation of lymphocyte proliferation

regulation of lymphocyte proliferation [inference]

positive regulation of lymphocyte proliferation

positive regulation of leukocyte proliferation [inference]

positive regulation of mononuclear cell proliferation [inference]

positive regulation of lymphocyte proliferation

regulation of cellular component biogenesis [inference]

regulation of actin filament bundle assembly [inference]

positive regulation of actin filament bundle assembly [inference]

positive regulation of stress fiber assembly

regulation of stress fiber assembly [inference]

positive regulation of stress fiber assembly

positive regulation of cellular component biogenesis [inference]

positive regulation of actin filament bundle assembly [inference]

positive regulation of stress fiber assembly

positive regulation of cellular process [inference]

positive regulation of cilium movement [inference]

positive regulation of flagellated sperm motility

positive regulation of cell population proliferation [inference]

positive regulation of epithelial cell proliferation

positive regulation of leukocyte proliferation [inference]

positive regulation of mononuclear cell proliferation [inference]

positive regulation of lymphocyte proliferation

positive regulation of cell communication [inference]

positive regulation of hormone secretion

positive regulation of synaptic transmission [inference]

positive regulation of cellular component biogenesis [inference]

positive regulation of actin filament bundle assembly [inference]

positive regulation of stress fiber assembly

positive regulation of cell activation [inference]

positive regulation of leukocyte activation [inference]

positive regulation of lymphocyte activation [inference]

positive regulation of lymphocyte proliferation

positive regulation of cellular component organization [inference]

positive regulation of organelle organization [inference]

positive regulation of cytoskeleton organization [inference]

positive regulation of actin filament bundle assembly [inference]

positive regulation of stress fiber assembly

positive regulation of supramolecular fiber organization [inference]

positive regulation of actin filament bundle assembly [inference]

positive regulation of stress fiber assembly

positive regulation of secretion by cell [inference]

positive regulation of hormone secretion

positive regulation of cell motility [inference]

positive regulation of cell migration [inference]

positive regulation of cilium-dependent cell motility [inference]

positive regulation of flagellated sperm motility

regulation of cell activation [inference]

regulation of leukocyte activation [inference]

positive regulation of leukocyte activation [inference]

positive regulation of lymphocyte activation [inference]

positive regulation of lymphocyte proliferation

regulation of lymphocyte activation [inference]

regulation of lymphocyte proliferation [inference]

positive regulation of lymphocyte proliferation

positive regulation of lymphocyte activation [inference]

positive regulation of lymphocyte proliferation

positive regulation of cell activation [inference]

positive regulation of leukocyte activation [inference]

positive regulation of lymphocyte activation [inference]

positive regulation of lymphocyte proliferation

regulation of cellular component organization [inference]

regulation of organelle organization [inference]

positive regulation of organelle organization [inference]

positive regulation of cytoskeleton organization [inference]

positive regulation of actin filament bundle assembly [inference]

positive regulation of stress fiber assembly

regulation of cytoskeleton organization [inference]

regulation of actin cytoskeleton organization [inference]

regulation of actomyosin structure organization [inference]

regulation of stress fiber assembly [inference]

positive regulation of stress fiber assembly

regulation of actin filament organization [inference]

regulation of actin filament bundle assembly [inference]

positive regulation of actin filament bundle assembly [inference]

positive regulation of stress fiber assembly

regulation of stress fiber assembly [inference]

positive regulation of stress fiber assembly

positive regulation of cytoskeleton organization [inference]

positive regulation of actin filament bundle assembly [inference]

positive regulation of stress fiber assembly

positive regulation of cellular component organization [inference]

positive regulation of organelle organization [inference]

positive regulation of cytoskeleton organization [inference]

positive regulation of actin filament bundle assembly [inference]

positive regulation of stress fiber assembly

positive regulation of supramolecular fiber organization [inference]

positive regulation of actin filament bundle assembly [inference]

positive regulation of stress fiber assembly

regulation of supramolecular fiber organization [inference]

regulation of actin filament organization [inference]

regulation of actin filament bundle assembly [inference]

positive regulation of actin filament bundle assembly [inference]

positive regulation of stress fiber assembly

regulation of stress fiber assembly [inference]

positive regulation of stress fiber assembly

positive regulation of supramolecular fiber organization [inference]

positive regulation of actin filament bundle assembly [inference]

positive regulation of stress fiber assembly

regulation of secretion by cell [inference]

regulation of hormone secretion [inference]

positive regulation of hormone secretion

positive regulation of secretion by cell [inference]

positive regulation of hormone secretion

regulation of cell motility [inference]

regulation of cell migration [inference]

regulation of leukocyte migration [inference]

positive regulation of leukocyte migration

regulation of epithelial cell migration [inference]

positive regulation of epithelial cell migration

regulation of smooth muscle cell migration

positive regulation of cell migration [inference]

regulation of cilium-dependent cell motility [inference]

regulation of cilium movement involved in cell motility [inference]

regulation of flagellated sperm motility [inference]

positive regulation of flagellated sperm motility

positive regulation of cilium-dependent cell motility [inference]

positive regulation of flagellated sperm motility

positive regulation of cell motility [inference]

positive regulation of cell migration [inference]

positive regulation of cilium-dependent cell motility [inference]

positive regulation of flagellated sperm motility

regulation of multicellular organismal process [inference]

regulation of epithelial cell migration [inference]

positive regulation of epithelial cell migration

regulation of ossification [inference]

positive regulation of ossification

regulation of system process [inference]

regulation of muscle system process [inference]

regulation of muscle contraction [inference]

regulation of smooth muscle contraction [inference]

positive regulation of smooth muscle contraction [inference]

positive regulation of uterine smooth muscle contraction

regulation of uterine smooth muscle contraction [inference]

positive regulation of uterine smooth muscle contraction

positive regulation of muscle contraction [inference]

positive regulation of smooth muscle contraction [inference]

positive regulation of uterine smooth muscle contraction

regulation of blood circulation [inference]

regulation of vasoconstriction [inference]

positive regulation of vasoconstriction

regulation of cell activation [inference]

regulation of leukocyte activation [inference]

positive regulation of leukocyte activation [inference]

positive regulation of lymphocyte activation [inference]

positive regulation of lymphocyte proliferation

regulation of lymphocyte activation [inference]

regulation of lymphocyte proliferation [inference]

positive regulation of lymphocyte proliferation

positive regulation of lymphocyte activation [inference]

positive regulation of lymphocyte proliferation

positive regulation of cell activation [inference]

positive regulation of leukocyte activation [inference]

positive regulation of lymphocyte activation [inference]

positive regulation of lymphocyte proliferation

positive regulation of multicellular organismal process [inference]

positive regulation of muscle contraction [inference]

positive regulation of smooth muscle contraction [inference]

positive regulation of uterine smooth muscle contraction

positive regulation of cell activation [inference]

positive regulation of leukocyte activation [inference]

positive regulation of lymphocyte activation [inference]

positive regulation of lymphocyte proliferation

regulation of action potential [inference]

positive regulation of action potential

regulation of reproductive process [inference]

regulation of flagellated sperm motility [inference]

positive regulation of flagellated sperm motility

positive regulation of reproductive process [inference]

positive regulation of flagellated sperm motility

regulation of biological quality [inference]

positive regulation of cytosolic calcium ion concentration

regulation of blood pressure [inference]

positive regulation of blood pressure

regulation of hormone levels [inference]

regulation of hormone secretion [inference]

positive regulation of hormone secretion

regulation of membrane potential [inference]

regulation of action potential [inference]

positive regulation of action potential

regulation of vascular permeability [inference]

positive regulation of vascular permeability

regulation of anatomical structure size [inference]

regulation of tube size [inference]

regulation of tube diameter [inference]

blood vessel diameter maintenance [inference]

regulation of vasoconstriction [inference]

positive regulation of vasoconstriction

Displaying entries **1 - 5** of 11 in total

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GO Term	Evidence Code	PMID
plasma membrane	TAS
plasma membrane	IDA	17986524
plasma membrane	IBA
cell surface	IEA
dendrite	IEA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

cell surface

membrane [inference]

plasma membrane

plasma membrane region [inference]

synaptic membrane [inference]

postsynaptic membrane

cell projection [inference]

plasma membrane bounded cell projection [inference]

cilium [inference]

motile cilium [inference]

9+2 motile cilium [inference]

sperm flagellum

neuron projection [inference]

dendrite

organelle [inference]

membrane-bounded organelle [inference]

cilium [inference]

motile cilium [inference]

9+2 motile cilium [inference]

sperm flagellum

Displaying **all 4** entries
GO Term	Evidence Code	PMID
tachykinin receptor activity	TAS	8985172
protein binding	IPI	12716968 17986524 23597562 32296183
substance P receptor activity	IMP	12716968
substance P receptor activity	IBA

GO Hierarchy

molecular function

binding [inference]

protein binding

molecular transducer activity [inference]

signaling receptor activity [inference]

peptide receptor activity [inference]

G protein-coupled peptide receptor activity [inference]

neuropeptide receptor activity [inference]

tachykinin receptor activity

substance P receptor activity

transmembrane signaling receptor activity [inference]

G protein-coupled receptor activity [inference]

G protein-coupled peptide receptor activity [inference]

neuropeptide receptor activity [inference]

tachykinin receptor activity

substance P receptor activity

Gene Ontology information from NCBI Gene and UniProt.

Disease

Disease Ontology

Displaying **all 2** entries
DO ID	Disease Name	Source
DOID:0060037	developmental disorder of mental health	Alliance of Genome Resources
DOID:0080821	exercise-induced bronchoconstriction	Alliance of Genome Resources

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