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propionyl-CoA carboxylase subunit alpha
Summary
- Gene Symbol
-
- Pcca
- Organism
- Rattus norvegicus (Norway rat)
Annotation
- Keyword
-
- ATP-binding
- Acetylation
- Biotin
- Direct protein sequencing
- Ligase
- Lipid degradation
- Magnesium
- Manganese
- Metal-binding
- Mitochondrion
- Phosphoprotein
- Reference proteome
- Transit peptide
- Proteins
| UniProt | Protein Name |
|---|---|
| P14882 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| carboxylic acid metabolic process | ||
| fatty acid catabolic process | ||
| lipid catabolic process | ||
| amino acid catabolic process |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| catalytic complex | ||
| mitochondrion | ||
| mitochondrial matrix |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| enzyme binding | ||
| metal ion binding | ||
| propionyl-CoA carboxylase activity | ||
| ATP binding | ||
| ligase activity |
OrthoDB (Group)
- Group level
- Rodentia
- Group Name
- propionyl-CoA carboxylase alpha chain, mitochondrial
- Functional Category
-
- C: Energy production and conversion
- E: Amino acid transport and metabolism
- I: Lipid transport and metabolism
- M: Cell wall/membrane/envelope biogenesis
| Gene Ontology |
|---|
| ATP binding |
| ligase activity |
| metal ion binding |
| methylcrotonoyl-CoA carboxylase activity |
| nucleotide binding |
| propionyl-CoA carboxylase activity |
| urea carboxylase activity |
| InterPro |
|---|
| Rudiment single hybrid motif |
| Single hybrid motif |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:14701 | propionic acidemia | |
| DOID:9252 | amino acid metabolic disorder |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 126506644 | 100897_0:0021e8 | |||
| 127202285 | 60746_0:002ee2 | |||
| 127230086 | 109678_0:0032d7 | |||
| 127691004 | 10129_0:0029d7 | |||
| 128107011 | 564181_0:0008ee | |||
| 129678714 | 48139_1:001bea | |||
| 130884762 | 269649_0:00345f | |||
| 131919119 | 42410_0:003404 |
