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Standards Ontologies Notations
propionyl-CoA carboxylase subunit alpha

Summary
Gene Symbol
  • Pcca
Organism
Rattus norvegicus (Norway rat)
NCBI Gene
687008
PubChem
687008
Alliance of Genome Resources
Annotation
Keyword
  • ATP-binding
  • Acetylation
  • Biotin
  • Direct protein sequencing
  • Ligase
  • Lipid degradation
  • Magnesium
  • Manganese
  • Metal-binding
  • Mitochondrion
  • Phosphoprotein
  • Reference proteome
  • Transit peptide
Proteins
Displaying 1 entry
UniProt Protein Name
P14882
  • Propanoyl-CoA:carbon dioxide ligase subunit alpha
Annotation information from UniProt.
Gene Ontology (GO)
Displaying all 4 entries
GO Term Evidence Code PMID
carboxylic acid metabolic process
fatty acid catabolic process
lipid catabolic process
amino acid catabolic process
GO Hierarchy
Displaying all 5 entries
GO Term Evidence Code PMID
enzyme binding
metal ion binding
propionyl-CoA carboxylase activity
ATP binding
ligase activity
GO Hierarchy
Gene Ontology information from NCBI Gene and UniProt.
OrthoDB (Group)
Group level
Rodentia
Group Name
propionyl-CoA carboxylase alpha chain, mitochondrial
Functional Category
  • C: Energy production and conversion
  • E: Amino acid transport and metabolism
  • I: Lipid transport and metabolism
  • M: Cell wall/membrane/envelope biogenesis
Displaying all 7 entries
Gene Ontology
ATP binding
ligase activity
metal ion binding
methylcrotonoyl-CoA carboxylase activity
nucleotide binding
propionyl-CoA carboxylase activity
urea carboxylase activity
Displaying entries 1 - 10 of 12 in total
InterPro
ATP-grasp fold, subdomain 1
ATP-grasp fold
Biotin carboxylase, C-terminal
Biotin carboxylase-like, N-terminal domain
Biotin carboxylation domain
Biotin-binding site
Biotin/lipoyl attachment
Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain
Pre-ATP-grasp domain superfamily
Propionyl-coenzyme A carboxylase, BT domain
Disease
Disease Ontology
Displaying all 2 entries
DO ID Disease Name Source
DOID:14701 propionic acidemia
DOID:9252 amino acid metabolic disorder
Ortholog
Displaying entries 91 - 100 of 108 in total
Species Gene ID OrthoDB Alliance of Genome Resources Orthologous MAtrix
118883970 BALMU14662
119800229 1047088_0:0047af
121462798 111838_0:00039a
122110156 105255_0:00198d
122122682 105255_0:003545
122214501 PANLE24763
124099648 9995_0:001d38
124985473 30640_0:001ceb
125348133 214514_0:001076
125392430 447135_0:004459
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GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: December 9, 2024