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dynein axonemal intermediate chain 1

Summary

Gene Symbol

Dnai1

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

68922

PubChem

68922

Alliance of Genome Resources

MGI:1916172

Annotation

Keyword

Cilium
Cytoskeleton
Dynein
Microtubule
Motor protein
Phosphoprotein
Reference proteome
Repeat
WD repeat

Proteins

Displaying **all 2** entries
UniProt	Protein Name
A2ANP4
Q8C0M8	Axonemal dynein intermediate chain 1

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 12 in total

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GO Term	Evidence Code	PMID
cilium movement	ISO
cilium movement	IBA
epithelial cilium movement involved in extracellular fluid movement	IMP	20498047
determination of left/right symmetry	ISO
determination of left/right symmetry	IMP	25807483

GO Hierarchy

biological process

cellular process [inference]

microtubule-based process [inference]

microtubule-based movement [inference]

cilium movement

epithelial cilium movement involved in extracellular fluid movement

cilium movement involved in cell motility [inference]

flagellated sperm motility

signal transduction [inference]

cell surface receptor signaling pathway [inference]

enzyme-linked receptor protein signaling pathway [inference]

transmembrane receptor protein tyrosine kinase signaling pathway [inference]

insulin receptor signaling pathway

cell motility [inference]

cilium or flagellum-dependent cell motility [inference]

cilium-dependent cell motility [inference]

flagellated sperm motility

sperm motility [inference]

flagellated sperm motility

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cellular component assembly [inference]

protein-containing complex assembly [inference]

axonemal dynein complex assembly [inference]

outer dynein arm assembly

protein-containing complex organization [inference]

protein-containing complex assembly [inference]

axonemal dynein complex assembly [inference]

outer dynein arm assembly

reproductive process [inference]

sperm motility [inference]

flagellated sperm motility

multicellular organismal process [inference]

pattern specification process [inference]

specification of symmetry [inference]

determination of bilateral symmetry [inference]

determination of left/right symmetry

developmental process [inference]

anatomical structure development [inference]

animal organ development [inference]

heart development

localization [inference]

establishment of localization [inference]

transport [inference]

extracellular transport [inference]

epithelial cilium movement involved in extracellular fluid movement

microtubule-based transport [inference]

epithelial cilium movement involved in extracellular fluid movement

biological regulation [inference]

regulation of biological process [inference]

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

enzyme-linked receptor protein signaling pathway [inference]

transmembrane receptor protein tyrosine kinase signaling pathway [inference]

insulin receptor signaling pathway

Displaying entries **1 - 5** of 10 in total

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GO Term	Evidence Code	PMID
extracellular region	IEA
cytoplasm	IDA	28057765
centrosome	IDA	28057765
microtubule	IEA
cilium	ISO

GO Hierarchy

cellular component

protein-containing complex [inference]

microtubule associated complex [inference]

dynein complex [inference]

axonemal dynein complex [inference]

outer dynein arm

catalytic complex [inference]

dynein complex [inference]

axonemal dynein complex [inference]

outer dynein arm

cellular anatomical entity [inference]

microtubule organizing center [inference]

centrosome

cell projection [inference]

plasma membrane bounded cell projection [inference]

cilium

motile cilium [inference]

9+2 motile cilium

glial cell projection

organelle [inference]

membrane-bounded organelle [inference]

cilium

motile cilium [inference]

9+2 motile cilium

supramolecular complex [inference]

supramolecular polymer [inference]

supramolecular fiber [inference]

polymeric cytoskeletal fiber [inference]

microtubule

Displaying **all 3** entries
GO Term	Evidence Code	PMID
protein binding	IPI	28057765 29916806
dynein light chain binding	IBA
dynein heavy chain binding	IBA

GO Hierarchy

molecular function

binding [inference]

protein binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Dynein intermediate chain

Functional Category

G: Carbohydrate transport and metabolism
L: Replication, recombination and repair
O: Posttranslational modification, protein turnover, chaperones

Displaying **all 3** entries
Gene Ontology
dynein heavy chain binding
dynein light chain binding
outer dynein arm assembly

Displaying **all 3** entries
InterPro
WD40 repeat
WD40-repeat-containing domain superfamily
WD40/YVTN repeat-like-containing domain superfamily

Disease

Disease Ontology

Displaying **all 3** entries
DO ID	Disease Name	Source
DOID:0050144	Kartagener syndrome	Alliance of Genome Resources
DOID:0050545	visceral heterotaxy	Alliance of Genome Resources
DOID:0110594	primary ciliary dyskinesia 1	Alliance of Genome Resources

Ortholog

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Homo sapiens	27019		HUMAN96805
Danio rerio	68922	ZFIN:ZDB-GENE-040910-7
Pan troglodytes	465060		PANTR43852
Canis lupus familiaris	474749		CANLF02258
Rattus norvegicus	500442		RATNO32794
Bos taurus	524709		BOVIN34832
Danio rerio	555705		DANRE21555
Macaca mulatta	701307		MACMU12509
Ciona intestinalis	778840		CIOIN07559
Monodelphis domestica	100028940		MONDO28268

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Annotation

OrthoDB (Group)

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Acknowledgements