Submissions
GlyTouCan
Glycan Structure Repository
GlyComb
Glycoconjugate Repository
GlycoPOST
Glycomics MS raw data Repository
UniCarb-DR
Glycomics MS Repository for glycan annotations from GlycoWorkbench
LM-GlycoRepo
Repository for lectin-assisted multimodality data
Resources Genes Glycoproteins Lectins Glycolipids Glycans Pathways Diseases Organisms
All Resources
Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Other Information
Release Statistics Download
Tools
SugarDrawer GlycanBuilder Glycan Converters GlycoMaple GlycomeAtlas LM-GlycomeAtlas GALAXY MCAW GlycoSim GRable
Search Tools
Cross Search Glycan Search Publication Search Programmatic Access
Standards Ontologies Notations
Guidelines
MIRAGE
ryanodine receptor 2

Summary
Gene Symbol
  • Ryr2
Organism
Rattus norvegicus (Norway rat)
NCBI Gene
689560
PubChem
689560
Alliance of Genome Resources
Annotation
Keyword
  • 3D-structure
  • Alternative splicing
  • Calcium channel
  • Calmodulin-binding
  • Developmental protein
  • Ligand-gated ion channel
  • Phosphoprotein
  • Receptor
  • Reference proteome
  • Repeat
  • Sarcoplasmic reticulum
  • Transmembrane helix
Proteins
Displaying 1 entry
UniProt Protein Name
B0LPN4
  • Cardiac muscle ryanodine receptor
  • Cardiac muscle ryanodine receptor-calcium release channel
  • Type 2 ryanodine receptor
Annotation information from UniProt.
Gene Ontology (GO)
Displaying entries 1 - 5 of 59 in total
GO Term Evidence Code PMID
response to hypoxia
response to hypoxia
regulation of heart rate
embryonic heart tube morphogenesis
embryonic heart tube morphogenesis
GO Hierarchy
Displaying entries 11 - 15 of 24 in total
GO Term Evidence Code PMID
extrinsic component of cytoplasmic side of plasma membrane
A band
protein-containing complex
protein-containing complex
protein-containing complex
GO Hierarchy
Displaying entries 1 - 5 of 24 in total
GO Term Evidence Code PMID
ryanodine-sensitive calcium-release channel activity
ryanodine-sensitive calcium-release channel activity
ryanodine-sensitive calcium-release channel activity
ryanodine-sensitive calcium-release channel activity
ryanodine-sensitive calcium-release channel activity
GO Hierarchy
Gene Ontology information from NCBI Gene and UniProt.
OrthoDB (Group)
Group level
Eukaryota
Group Name
ryanodine receptor
Functional Category
  • E: Amino acid transport and metabolism
  • K: Transcription
  • T: Signal transduction mechanisms
Displaying all 10 entries
Gene Ontology
calcium channel activity
calcium ion transmembrane transport
calcium ion transport
calcium-mediated signaling
intracellular calcium ion homeostasis
monoatomic ion channel activity
monoatomic ion transport
release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
ryanodine-sensitive calcium-release channel activity
striated muscle contraction
Displaying entries 1 - 10 of 19 in total
InterPro
B30.2/SPRY domain superfamily
B30.2/SPRY domain
Concanavalin A-like lectin/glucanase domain superfamily
EF-hand domain pair
Inositol 1,4,5-trisphosphate/ryanodine receptor
Ion transport domain
MIR motif
Mir domain superfamily
RIH domain
RyR/IP3 receptor binding core, RIH domain superfamily
Alliance of Genome Resources
Expression
Displaying all 6 entries
Location References
Disease
Disease Ontology
Displaying 1 entry
DO ID Disease Name Source
DOID:6000 congestive heart failure
Ortholog
Displaying entries 61 - 65 of 65 in total
Species Gene ID Alliance of Genome Resources Orthologous MAtrix
116440894 CORMO18246
117018496 RHIFE03597
118287596 SCOMX11842
118882498 BALMU15680
122201785 PANLE03210
About Release Notes Help Feedback
International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

Logo License Policies Site Map

Contact: support@glycosmos.org

This work is licensed under Creative Commons Attribution 4.0 International

GlyCosmos Portal v4.4.0

Last updated: December 8, 2025