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Guidelines

MIRAGE

acylglycerol kinase

Summary

Gene Symbol

AGK

Organism

Macaca mulatta (Rhesus monkey)

External Links

NCBI Gene: 694070
KEGG Gene ID: mcc:694070
PubChem: 694070

Annotation

Keyword

Kinase
Mitochondrion inner membrane

Proteins

Displaying 1 entry
UniProt	Protein Name
I0FJR1	Multiple substrate lipid kinase

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 2** entries
GO Term	Evidence Code	PMID
protein insertion into mitochondrial inner membrane	IEA	30032202
ceramide biosynthetic process	IEA	30032202

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

cellular nitrogen compound biosynthetic process [inference]

amide biosynthetic process [inference]

ceramide biosynthetic process

amide metabolic process [inference]

ceramide metabolic process [inference]

ceramide biosynthetic process

amide biosynthetic process [inference]

ceramide biosynthetic process

organonitrogen compound metabolic process [inference]

sphingolipid metabolic process [inference]

ceramide metabolic process [inference]

ceramide biosynthetic process

sphingolipid biosynthetic process [inference]

ceramide biosynthetic process

organonitrogen compound biosynthetic process [inference]

sphingolipid biosynthetic process [inference]

ceramide biosynthetic process

biosynthetic process [inference]

cellular biosynthetic process [inference]

cellular nitrogen compound biosynthetic process [inference]

amide biosynthetic process [inference]

ceramide biosynthetic process

membrane lipid biosynthetic process [inference]

sphingolipid biosynthetic process [inference]

ceramide biosynthetic process

organic substance biosynthetic process [inference]

lipid biosynthetic process [inference]

membrane lipid biosynthetic process [inference]

sphingolipid biosynthetic process [inference]

ceramide biosynthetic process

organonitrogen compound biosynthetic process [inference]

sphingolipid biosynthetic process [inference]

ceramide biosynthetic process

cellular metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

cellular nitrogen compound biosynthetic process [inference]

amide biosynthetic process [inference]

ceramide biosynthetic process

cellular biosynthetic process [inference]

cellular nitrogen compound biosynthetic process [inference]

amide biosynthetic process [inference]

ceramide biosynthetic process

membrane lipid biosynthetic process [inference]

sphingolipid biosynthetic process [inference]

ceramide biosynthetic process

cellular lipid metabolic process [inference]

membrane lipid metabolic process [inference]

sphingolipid metabolic process [inference]

ceramide metabolic process [inference]

ceramide biosynthetic process

sphingolipid biosynthetic process [inference]

ceramide biosynthetic process

membrane lipid biosynthetic process [inference]

sphingolipid biosynthetic process [inference]

ceramide biosynthetic process

primary metabolic process [inference]

lipid metabolic process [inference]

lipid biosynthetic process [inference]

membrane lipid biosynthetic process [inference]

sphingolipid biosynthetic process [inference]

ceramide biosynthetic process

cellular lipid metabolic process [inference]

membrane lipid metabolic process [inference]

sphingolipid metabolic process [inference]

ceramide metabolic process [inference]

ceramide biosynthetic process

sphingolipid biosynthetic process [inference]

ceramide biosynthetic process

membrane lipid biosynthetic process [inference]

sphingolipid biosynthetic process [inference]

ceramide biosynthetic process

organic substance metabolic process [inference]

lipid metabolic process [inference]

lipid biosynthetic process [inference]

membrane lipid biosynthetic process [inference]

sphingolipid biosynthetic process [inference]

ceramide biosynthetic process

cellular lipid metabolic process [inference]

membrane lipid metabolic process [inference]

sphingolipid metabolic process [inference]

ceramide metabolic process [inference]

ceramide biosynthetic process

sphingolipid biosynthetic process [inference]

ceramide biosynthetic process

membrane lipid biosynthetic process [inference]

sphingolipid biosynthetic process [inference]

ceramide biosynthetic process

organonitrogen compound metabolic process [inference]

sphingolipid metabolic process [inference]

ceramide metabolic process [inference]

ceramide biosynthetic process

sphingolipid biosynthetic process [inference]

ceramide biosynthetic process

organonitrogen compound biosynthetic process [inference]

sphingolipid biosynthetic process [inference]

ceramide biosynthetic process

organic substance biosynthetic process [inference]

lipid biosynthetic process [inference]

membrane lipid biosynthetic process [inference]

sphingolipid biosynthetic process [inference]

ceramide biosynthetic process

organonitrogen compound biosynthetic process [inference]

sphingolipid biosynthetic process [inference]

ceramide biosynthetic process

cellular process [inference]

cellular metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

cellular nitrogen compound biosynthetic process [inference]

amide biosynthetic process [inference]

ceramide biosynthetic process

cellular biosynthetic process [inference]

cellular nitrogen compound biosynthetic process [inference]

amide biosynthetic process [inference]

ceramide biosynthetic process

membrane lipid biosynthetic process [inference]

sphingolipid biosynthetic process [inference]

ceramide biosynthetic process

cellular lipid metabolic process [inference]

membrane lipid metabolic process [inference]

sphingolipid metabolic process [inference]

ceramide metabolic process [inference]

ceramide biosynthetic process

sphingolipid biosynthetic process [inference]

ceramide biosynthetic process

membrane lipid biosynthetic process [inference]

sphingolipid biosynthetic process [inference]

ceramide biosynthetic process

cellular localization [inference]

intracellular transport [inference]

intracellular protein transport [inference]

protein insertion into mitochondrial inner membrane

localization within membrane [inference]

protein localization to membrane [inference]

establishment of protein localization to membrane [inference]

establishment of protein localization to mitochondrial membrane [inference]

protein insertion into mitochondrial inner membrane

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to organelle [inference]

protein localization to mitochondrion [inference]

establishment of protein localization to mitochondrion [inference]

establishment of protein localization to mitochondrial membrane [inference]

protein insertion into mitochondrial inner membrane

establishment of protein localization to organelle [inference]

establishment of protein localization to mitochondrion [inference]

establishment of protein localization to mitochondrial membrane [inference]

protein insertion into mitochondrial inner membrane

establishment of protein localization [inference]

protein transport [inference]

intracellular protein transport [inference]

protein insertion into mitochondrial inner membrane

establishment of protein localization to organelle [inference]

establishment of protein localization to mitochondrion [inference]

establishment of protein localization to mitochondrial membrane [inference]

protein insertion into mitochondrial inner membrane

establishment of protein localization to membrane [inference]

establishment of protein localization to mitochondrial membrane [inference]

protein insertion into mitochondrial inner membrane

protein localization to membrane [inference]

establishment of protein localization to membrane [inference]

establishment of protein localization to mitochondrial membrane [inference]

protein insertion into mitochondrial inner membrane

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

mitochondrion organization [inference]

mitochondrial membrane organization [inference]

inner mitochondrial membrane organization [inference]

protein insertion into mitochondrial inner membrane

establishment of protein localization to mitochondrial membrane [inference]

protein insertion into mitochondrial inner membrane

membrane organization [inference]

mitochondrial membrane organization [inference]

inner mitochondrial membrane organization [inference]

protein insertion into mitochondrial inner membrane

establishment of protein localization to mitochondrial membrane [inference]

protein insertion into mitochondrial inner membrane

localization [inference]

macromolecule localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to organelle [inference]

protein localization to mitochondrion [inference]

establishment of protein localization to mitochondrion [inference]

establishment of protein localization to mitochondrial membrane [inference]

protein insertion into mitochondrial inner membrane

establishment of protein localization to organelle [inference]

establishment of protein localization to mitochondrion [inference]

establishment of protein localization to mitochondrial membrane [inference]

protein insertion into mitochondrial inner membrane

establishment of protein localization [inference]

protein transport [inference]

intracellular protein transport [inference]

protein insertion into mitochondrial inner membrane

establishment of protein localization to organelle [inference]

establishment of protein localization to mitochondrion [inference]

establishment of protein localization to mitochondrial membrane [inference]

protein insertion into mitochondrial inner membrane

establishment of protein localization to membrane [inference]

establishment of protein localization to mitochondrial membrane [inference]

protein insertion into mitochondrial inner membrane

protein localization to membrane [inference]

establishment of protein localization to membrane [inference]

establishment of protein localization to mitochondrial membrane [inference]

protein insertion into mitochondrial inner membrane

establishment of localization [inference]

transport [inference]

mitochondrial transport [inference]

protein insertion into mitochondrial inner membrane

intracellular transport [inference]

intracellular protein transport [inference]

protein insertion into mitochondrial inner membrane

organic substance transport [inference]

protein transport [inference]

intracellular protein transport [inference]

protein insertion into mitochondrial inner membrane

nitrogen compound transport [inference]

protein transport [inference]

intracellular protein transport [inference]

protein insertion into mitochondrial inner membrane

establishment of protein localization [inference]

protein transport [inference]

intracellular protein transport [inference]

protein insertion into mitochondrial inner membrane

establishment of protein localization to organelle [inference]

establishment of protein localization to mitochondrion [inference]

establishment of protein localization to mitochondrial membrane [inference]

protein insertion into mitochondrial inner membrane

establishment of protein localization to membrane [inference]

establishment of protein localization to mitochondrial membrane [inference]

protein insertion into mitochondrial inner membrane

establishment of localization in cell [inference]

intracellular transport [inference]

intracellular protein transport [inference]

protein insertion into mitochondrial inner membrane

establishment of protein localization to mitochondrial membrane [inference]

protein insertion into mitochondrial inner membrane

cellular localization [inference]

intracellular transport [inference]

intracellular protein transport [inference]

protein insertion into mitochondrial inner membrane

localization within membrane [inference]

protein localization to membrane [inference]

establishment of protein localization to membrane [inference]

establishment of protein localization to mitochondrial membrane [inference]

protein insertion into mitochondrial inner membrane

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to organelle [inference]

protein localization to mitochondrion [inference]

establishment of protein localization to mitochondrion [inference]

establishment of protein localization to mitochondrial membrane [inference]

protein insertion into mitochondrial inner membrane

establishment of protein localization to organelle [inference]

establishment of protein localization to mitochondrion [inference]

establishment of protein localization to mitochondrial membrane [inference]

protein insertion into mitochondrial inner membrane

establishment of protein localization [inference]

protein transport [inference]

intracellular protein transport [inference]

protein insertion into mitochondrial inner membrane

establishment of protein localization to organelle [inference]

establishment of protein localization to mitochondrion [inference]

establishment of protein localization to mitochondrial membrane [inference]

protein insertion into mitochondrial inner membrane

establishment of protein localization to membrane [inference]

establishment of protein localization to mitochondrial membrane [inference]

protein insertion into mitochondrial inner membrane

protein localization to membrane [inference]

establishment of protein localization to membrane [inference]

establishment of protein localization to mitochondrial membrane [inference]

protein insertion into mitochondrial inner membrane

Displaying **all 2** entries
GO Term	Evidence Code	PMID
mitochondrion	IEA	30032202
TIM22 mitochondrial import inner membrane insertion complex	IEA	30032202

GO Hierarchy

cellular component

protein-containing complex [inference]

membrane protein complex [inference]

inner mitochondrial membrane protein complex [inference]

TIM22 mitochondrial import inner membrane insertion complex

mitochondrial protein-containing complex [inference]

inner mitochondrial membrane protein complex [inference]

TIM22 mitochondrial import inner membrane insertion complex

cellular anatomical entity [inference]

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

mitochondrion

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

mitochondrion

Displaying **all 3** entries
GO Term	Evidence Code	PMID
ceramide kinase activity	IEA	30032202
ATP-dependent diacylglycerol kinase activity	IEA	30032202
acylglycerol kinase activity	IEA	30032202

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

transferase activity, transferring phosphorus-containing groups [inference]

kinase activity [inference]

lipid kinase activity [inference]

acylglycerol kinase activity

phosphotransferase activity, alcohol group as acceptor [inference]

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Acylglycerol kinase

Functional Category

G: Carbohydrate transport and metabolism
I: Lipid transport and metabolism
T: Signal transduction mechanisms

Displaying **all 9** entries
Gene Ontology
ATP-dependent diacylglycerol kinase activity
D-erythro-sphingosine kinase activity
acylglycerol kinase activity
ceramide biosynthetic process
ceramide kinase activity
glycerolipid metabolic process
kinase activity
phosphorylation
sphingosine biosynthetic process

Displaying **all 4** entries
InterPro
Acylglycerol kinase, C-terminal
Diacylglycerol kinase, catalytic domain
Inorganic polyphosphate/ATP-NAD kinase, N-terminal
NAD kinase/diacylglycerol kinase-like domain superfamily

KEGG BRITE Database

Orthology

K09881

Name

acylglycerol kinase [EC:2.7.1.94]

References

15252046

Rhea

a 1,2-diacyl-sn-glycerol + ATP

H⁺ + ADP + a 1,2-diacyl-sn-glycero-3-phosphate

Enzyme

2.7.1.107

PMID

15939762

ATP + an N-acylsphing-4-enine

H⁺ + ADP + an N-acylsphing-4-enine 1-phosphate

Enzyme

2.7.1.138

PMID

a monoacylglycerol + ATP

H⁺ + ADP + monoacyl-sn-glycero-3-phosphate

Enzyme

2.7.1.94

PMID

LIPID MAPS Gene / Proteome Database

LMPD ID: LMP013742
Gene Name: acylglycerol kinase

Ortholog

Displaying entries **21 - 30** of 71 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Papio anubis	101025595		PAPAN29550
Saimiri boliviensis boliviensis	101027446		SAIBB16447
Takifugu rubripes	101076046		TAKRU51971
Felis catus	101092595		FELCA04793
Ovis aries	101108220		SHEEP15776
Gorilla gorilla gorilla	101147731		GORGO39092
Oryzias latipes	101156970		ORYLA15326
Mustela putorius furo	101670275		MUSPF17957
Heterocephalus glaber	101705295		HETGA01873
Melopsittacus undulatus	101872687		MELUD03345

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Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: December 8, 2025