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Guidelines

MIRAGE

nucleoporin 35

Summary

Gene Symbol

Nup35

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

69482

PubChem

69482

Alliance of Genome Resources

MGI:1916732

Annotation

Keyword

3D-structure
Direct protein sequencing
Membrane
Nuclear pore complex
Phosphoprotein
Reference proteome

Proteins

Displaying 1 entry
UniProt	Protein Name
Q8R4R6	35 kDa nucleoporin Mitotic phosphoprotein 44 Nuclear pore complex protein Nup53 Nucleoporin NUP53

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
NLS-bearing protein import into nucleus	IBA
nucleocytoplasmic transport	NAS	12791264
nuclear pore organization	IBA
protein transport	IEA
mRNA transport	IEA

GO Hierarchy

biological process

cellular process [inference]

cellular localization [inference]

intracellular transport [inference]

intracellular protein transport [inference]

protein import into nucleus [inference]

NLS-bearing protein import into nucleus

nuclear transport [inference]

nucleocytoplasmic transport

import into nucleus [inference]

protein import into nucleus [inference]

NLS-bearing protein import into nucleus

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to organelle [inference]

protein localization to nucleus [inference]

protein import into nucleus [inference]

NLS-bearing protein import into nucleus

establishment of protein localization to organelle [inference]

protein import into nucleus [inference]

NLS-bearing protein import into nucleus

establishment of protein localization [inference]

protein transport

intracellular protein transport [inference]

protein import into nucleus [inference]

NLS-bearing protein import into nucleus

establishment of protein localization to organelle [inference]

protein import into nucleus [inference]

NLS-bearing protein import into nucleus

cellular response to stimulus [inference]

cellular response to chemical stimulus [inference]

cellular response to organic substance [inference]

cellular response to cytokine stimulus [inference]

cellular response to leukemia inhibitory factor

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

nucleus organization [inference]

nuclear pore organization

protein-containing complex organization [inference]

nuclear pore organization

response to stimulus [inference]

response to chemical [inference]

response to organic substance [inference]

response to cytokine [inference]

cellular response to cytokine stimulus [inference]

cellular response to leukemia inhibitory factor

response to leukemia inhibitory factor [inference]

cellular response to leukemia inhibitory factor

cellular response to organic substance [inference]

cellular response to cytokine stimulus [inference]

cellular response to leukemia inhibitory factor

cellular response to chemical stimulus [inference]

cellular response to organic substance [inference]

cellular response to cytokine stimulus [inference]

cellular response to leukemia inhibitory factor

cellular response to stimulus [inference]

cellular response to chemical stimulus [inference]

cellular response to organic substance [inference]

cellular response to cytokine stimulus [inference]

cellular response to leukemia inhibitory factor

localization [inference]

macromolecule localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to organelle [inference]

protein localization to nucleus [inference]

protein import into nucleus [inference]

NLS-bearing protein import into nucleus

establishment of protein localization to organelle [inference]

protein import into nucleus [inference]

NLS-bearing protein import into nucleus

establishment of protein localization [inference]

protein transport

intracellular protein transport [inference]

protein import into nucleus [inference]

NLS-bearing protein import into nucleus

establishment of protein localization to organelle [inference]

protein import into nucleus [inference]

NLS-bearing protein import into nucleus

establishment of localization [inference]

transport [inference]

intracellular transport [inference]

intracellular protein transport [inference]

protein import into nucleus [inference]

NLS-bearing protein import into nucleus

nuclear transport [inference]

nucleocytoplasmic transport

import into nucleus [inference]

protein import into nucleus [inference]

NLS-bearing protein import into nucleus

organic substance transport [inference]

protein transport

intracellular protein transport [inference]

protein import into nucleus [inference]

NLS-bearing protein import into nucleus

nucleobase-containing compound transport [inference]

nucleic acid transport [inference]

RNA transport [inference]

mRNA transport

nitrogen compound transport [inference]

protein transport

intracellular protein transport [inference]

protein import into nucleus [inference]

NLS-bearing protein import into nucleus

nucleobase-containing compound transport [inference]

nucleic acid transport [inference]

RNA transport [inference]

mRNA transport

establishment of protein localization [inference]

protein transport

intracellular protein transport [inference]

protein import into nucleus [inference]

NLS-bearing protein import into nucleus

establishment of protein localization to organelle [inference]

protein import into nucleus [inference]

NLS-bearing protein import into nucleus

establishment of RNA localization [inference]

RNA transport [inference]

mRNA transport

establishment of localization in cell [inference]

intracellular transport [inference]

intracellular protein transport [inference]

protein import into nucleus [inference]

NLS-bearing protein import into nucleus

nuclear transport [inference]

nucleocytoplasmic transport

import into nucleus [inference]

protein import into nucleus [inference]

NLS-bearing protein import into nucleus

cellular localization [inference]

intracellular transport [inference]

intracellular protein transport [inference]

protein import into nucleus [inference]

NLS-bearing protein import into nucleus

nuclear transport [inference]

nucleocytoplasmic transport

import into nucleus [inference]

protein import into nucleus [inference]

NLS-bearing protein import into nucleus

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to organelle [inference]

protein localization to nucleus [inference]

protein import into nucleus [inference]

NLS-bearing protein import into nucleus

establishment of protein localization to organelle [inference]

protein import into nucleus [inference]

NLS-bearing protein import into nucleus

establishment of protein localization [inference]

protein transport

intracellular protein transport [inference]

protein import into nucleus [inference]

NLS-bearing protein import into nucleus

establishment of protein localization to organelle [inference]

protein import into nucleus [inference]

NLS-bearing protein import into nucleus

Displaying entries **1 - 5** of 11 in total

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GO Term	Evidence Code	PMID
nuclear envelope	ISO
nuclear pore	NAS	12791264
nuclear lamina	ISO
nucleoplasm	ISO
nucleoplasm	IEA

GO Hierarchy

cellular component

protein-containing complex [inference]

nuclear protein-containing complex [inference]

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

organelle membrane [inference]

nuclear membrane

envelope [inference]

organelle envelope [inference]

nuclear envelope

Displaying **all 5** entries
GO Term	Evidence Code	PMID
nucleic acid binding	IEA
phospholipid binding	IBA
structural constituent of nuclear pore	IBA
structural constituent of nuclear pore	IEA
identical protein binding	IPI	16962612

GO Hierarchy

molecular function

structural molecule activity [inference]

structural constituent of nuclear pore

binding [inference]

protein binding [inference]

identical protein binding

lipid binding [inference]

phospholipid binding

organic cyclic compound binding [inference]

nucleic acid binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

nucleoporin

Functional Category

E: Amino acid transport and metabolism
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 4** entries
Gene Ontology
NLS-bearing protein import into nucleus
mRNA transport
nuclear pore organization
phospholipid binding

Displaying **all 4** entries
InterPro
Nucleoporin, NUP53
Nucleotide-binding alpha-beta plait domain superfamily
RNA-binding domain superfamily
RNA-recognition motif (RRM) Nup35-type domain

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:0080072	intestinal pseudo-obstruction	Alliance of Genome Resources

Ortholog

Displaying entries **1 - 10** of 83 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Xenopus tropicalis	69482	Xenbase:XB-GENE-980941
Homo sapiens	129401	Xenbase:XB-GENE-980941	HUMAN65914
Rattus norvegicus	295692		RATNO26197
Danio rerio	337461		DANRE45384
Pan troglodytes	459802		PANTR29310
Bos taurus	511248		BOVIN23929
Macaca mulatta	706497		MACMU06193
Xenopus tropicalis	855184	Xenbase:XB-GENE-980941
Monodelphis domestica	100020462		MONDO21212
Equus caballus	100054143		HORSE13429

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Last updated: December 8, 2025