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endothelial cell-specific adhesion molecule

Summary

Gene Symbol

Esam

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

69524

PubChem

69524

Alliance of Genome Resources

MGI:1916774

Annotation

Keyword

Cell adhesion
Cell membrane
Disulfide bond
Glycoprotein
Immunoglobulin domain
Phosphoprotein
Reference proteome
Repeat
Signal
Tight junction
Transmembrane helix

Proteins

Displaying **all 2** entries
UniProt	Protein Name
Q925F2
Q3U102

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 12 in total

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GO Term	Evidence Code	PMID
homophilic cell adhesion via plasma membrane adhesion molecules	IDA	11847224
homophilic cell adhesion via plasma membrane adhesion molecules	IBA
protein localization	ISO
protein localization	IEA
calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules	TAS	11847224

GO Hierarchy

biological process

cellular process [inference]

cell adhesion [inference]

cell-cell adhesion

cell-cell adhesion via plasma-membrane adhesion molecules [inference]

cellular localization [inference]

cellular macromolecule localization [inference]

protein localization

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cellular component assembly [inference]

cell junction assembly [inference]

cell-cell junction assembly [inference]

tight junction assembly [inference]

bicellular tight junction assembly

regulation of cellular component size [inference]

regulation of actin filament length [inference]

regulation of actin polymerization or depolymerization [inference]

regulation of actin filament polymerization

cell junction organization [inference]

cell junction assembly [inference]

cell-cell junction assembly [inference]

tight junction assembly [inference]

bicellular tight junction assembly

cell-cell junction organization [inference]

cell-cell junction assembly [inference]

tight junction assembly [inference]

bicellular tight junction assembly

tight junction organization [inference]

tight junction assembly [inference]

bicellular tight junction assembly

localization [inference]

macromolecule localization [inference]

cellular macromolecule localization [inference]

protein localization

cellular localization [inference]

cellular macromolecule localization [inference]

protein localization

biological regulation [inference]

regulation of biological process [inference]

regulation of cellular process [inference]

regulation of actin filament-based process [inference]

regulation of actin cytoskeleton organization

regulation of actin filament length [inference]

regulation of actin polymerization or depolymerization [inference]

regulation of actin filament polymerization

regulation of actin filament organization [inference]

regulation of actin polymerization or depolymerization [inference]

regulation of actin filament polymerization

regulation of cellular component biogenesis [inference]

regulation of protein-containing complex assembly [inference]

regulation of protein polymerization [inference]

regulation of actin filament polymerization

regulation of cellular component organization [inference]

regulation of organelle organization [inference]

regulation of cytoskeleton organization [inference]

regulation of actin cytoskeleton organization

regulation of actin filament length [inference]

regulation of actin polymerization or depolymerization [inference]

regulation of actin filament polymerization

regulation of actin filament organization [inference]

regulation of actin polymerization or depolymerization [inference]

regulation of actin filament polymerization

regulation of protein-containing complex assembly [inference]

regulation of protein polymerization [inference]

regulation of actin filament polymerization

regulation of supramolecular fiber organization [inference]

regulation of actin filament organization [inference]

regulation of actin polymerization or depolymerization [inference]

regulation of actin filament polymerization

regulation of biological quality [inference]

regulation of anatomical structure size [inference]

regulation of cellular component size [inference]

regulation of actin filament length [inference]

regulation of actin polymerization or depolymerization [inference]

regulation of actin filament polymerization

Displaying entries **1 - 5** of 9 in total

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GO Term	Evidence Code	PMID
plasma membrane	ISO
plasma membrane	IDA	11279107
plasma membrane	IBA
cell-cell junction	ISO
adherens junction	IDA	11279107

GO Hierarchy

cellular component

protein-containing complex

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

cell junction [inference]

anchoring junction [inference]

cell-cell junction

adherens junction

tight junction [inference]

bicellular tight junction

Displaying **all 3** entries
GO Term	Evidence Code	PMID
cell-cell adhesion mediator activity	ISO
cell-cell adhesion mediator activity	IBA
cell-cell adhesion mediator activity	IEA

GO Hierarchy

molecular function

binding [inference]

protein binding [inference]

cell adhesion molecule binding [inference]

cell adhesion mediator activity [inference]

cell-cell adhesion mediator activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

endothelial cell adhesion molecule a

Functional Category

G: Carbohydrate transport and metabolism
M: Cell wall/membrane/envelope biogenesis
O: Posttranslational modification, protein turnover, chaperones

Displaying **all 2** entries
Gene Ontology
cell-cell adhesion mediator activity
homophilic cell adhesion via plasma membrane adhesion molecules

Displaying **all 6** entries
InterPro
Endothelial cell-selective adhesion molecule
Immunoglobulin subtype 2
Immunoglobulin subtype
Immunoglobulin-like domain superfamily
Immunoglobulin-like domain
Immunoglobulin-like fold

Ortholog

Displaying entries **1 - 10** of 88 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Xenopus tropicalis	69524	Xenbase:XB-GENE-963268
Homo sapiens	90952	Xenbase:XB-GENE-963268	HUMAN10033
Rattus norvegicus	300519	Xenbase:XB-GENE-963268	RATNO40175
Pan troglodytes	451639		PANTR04647
Canis lupus familiaris	489309		CANLF15127
Danio rerio	562934		DANRE08396
Bos taurus	616926		BOVIN23027
Macaca mulatta	712200		MACMU11135
Danio rerio	799432		DANRE01542
Monodelphis domestica	100017927		MONDO22115