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GlyTouCan

Glycan Structure Repository

GlyComb

Glycoconjugate Repository

GlycoPOST

Glycomics MS raw data Repository

UniCarb-DR

Glycomics MS Repository for glycan annotations from GlycoWorkbench

LM-GlycoRepo

Repository for lectin-assisted multimodality data

All Resources

Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms

Other Information

Release Statistics Download

Tools

Glycan Converters

LM-GlycomeAtlas

Search Tools

Cross Search Glycan Search Publication Search Programmatic Access

Guidelines

MIRAGE

glucosylceramidase beta 2

Summary

Gene Symbol

GBA2

Organism

Macaca mulatta (Rhesus monkey)

External Links

NCBI Gene: 696062
KEGG Gene ID: mcc:696062
PubChem: 696062

Annotation

Keyword

Endoplasmic reticulum
Glycosidase
Golgi apparatus
Lipid metabolism
Membrane
Reference proteome

Proteins

Displaying 1 entry
UniProt	Protein Name
G7NFD0

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 3** entries
GO Term	Evidence Code	PMID
carbohydrate metabolic process	IEA	22301074
glucosylceramide catabolic process	IEA	22301074
central nervous system development	IEA	30032202

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

amide metabolic process [inference]

ceramide metabolic process [inference]

glycosylceramide metabolic process [inference]

glucosylceramide metabolic process [inference]

glucosylceramide catabolic process

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

ceramide catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

organonitrogen compound metabolic process [inference]

sphingolipid metabolic process [inference]

ceramide metabolic process [inference]

glycosylceramide metabolic process [inference]

glucosylceramide metabolic process [inference]

glucosylceramide catabolic process

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

ceramide catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

glycosphingolipid metabolic process [inference]

glycosylceramide metabolic process [inference]

glucosylceramide metabolic process [inference]

glucosylceramide catabolic process

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

glycosphingolipid catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

sphingolipid catabolic process [inference]

glycosphingolipid catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

ceramide catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

organonitrogen compound catabolic process [inference]

sphingolipid catabolic process [inference]

glycosphingolipid catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

ceramide catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

catabolic process [inference]

cellular catabolic process [inference]

cellular lipid catabolic process [inference]

membrane lipid catabolic process [inference]

glycolipid catabolic process [inference]

glycosphingolipid catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

sphingolipid catabolic process [inference]

glycosphingolipid catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

ceramide catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

organic substance catabolic process [inference]

lipid catabolic process [inference]

cellular lipid catabolic process [inference]

membrane lipid catabolic process [inference]

glycolipid catabolic process [inference]

glycosphingolipid catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

sphingolipid catabolic process [inference]

glycosphingolipid catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

ceramide catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

carbohydrate derivative catabolic process [inference]

glycolipid catabolic process [inference]

glycosphingolipid catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

organonitrogen compound catabolic process [inference]

sphingolipid catabolic process [inference]

glycosphingolipid catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

ceramide catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

cellular metabolic process [inference]

cellular catabolic process [inference]

cellular lipid catabolic process [inference]

membrane lipid catabolic process [inference]

glycolipid catabolic process [inference]

glycosphingolipid catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

sphingolipid catabolic process [inference]

glycosphingolipid catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

ceramide catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

cellular lipid metabolic process [inference]

membrane lipid metabolic process [inference]

glycolipid metabolic process [inference]

glycosphingolipid metabolic process [inference]

glycosylceramide metabolic process [inference]

glucosylceramide metabolic process [inference]

glucosylceramide catabolic process

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

glycosphingolipid catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

glycolipid catabolic process [inference]

glycosphingolipid catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

sphingolipid metabolic process [inference]

ceramide metabolic process [inference]

glycosylceramide metabolic process [inference]

glucosylceramide metabolic process [inference]

glucosylceramide catabolic process

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

ceramide catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

glycosphingolipid metabolic process [inference]

glycosylceramide metabolic process [inference]

glucosylceramide metabolic process [inference]

glucosylceramide catabolic process

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

glycosphingolipid catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

sphingolipid catabolic process [inference]

glycosphingolipid catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

ceramide catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

membrane lipid catabolic process [inference]

glycolipid catabolic process [inference]

glycosphingolipid catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

sphingolipid catabolic process [inference]

glycosphingolipid catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

ceramide catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

cellular lipid catabolic process [inference]

membrane lipid catabolic process [inference]

glycolipid catabolic process [inference]

glycosphingolipid catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

sphingolipid catabolic process [inference]

glycosphingolipid catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

ceramide catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

primary metabolic process [inference]

carbohydrate metabolic process

lipid metabolic process [inference]

lipid catabolic process [inference]

cellular lipid catabolic process [inference]

membrane lipid catabolic process [inference]

glycolipid catabolic process [inference]

glycosphingolipid catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

sphingolipid catabolic process [inference]

glycosphingolipid catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

ceramide catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

cellular lipid metabolic process [inference]

membrane lipid metabolic process [inference]

glycolipid metabolic process [inference]

glycosphingolipid metabolic process [inference]

glycosylceramide metabolic process [inference]

glucosylceramide metabolic process [inference]

glucosylceramide catabolic process

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

glycosphingolipid catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

glycolipid catabolic process [inference]

glycosphingolipid catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

sphingolipid metabolic process [inference]

ceramide metabolic process [inference]

glycosylceramide metabolic process [inference]

glucosylceramide metabolic process [inference]

glucosylceramide catabolic process

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

ceramide catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

glycosphingolipid metabolic process [inference]

glycosylceramide metabolic process [inference]

glucosylceramide metabolic process [inference]

glucosylceramide catabolic process

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

glycosphingolipid catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

sphingolipid catabolic process [inference]

glycosphingolipid catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

ceramide catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

membrane lipid catabolic process [inference]

glycolipid catabolic process [inference]

glycosphingolipid catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

sphingolipid catabolic process [inference]

glycosphingolipid catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

ceramide catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

cellular lipid catabolic process [inference]

membrane lipid catabolic process [inference]

glycolipid catabolic process [inference]

glycosphingolipid catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

sphingolipid catabolic process [inference]

glycosphingolipid catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

ceramide catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

liposaccharide metabolic process [inference]

glycolipid metabolic process [inference]

glycosphingolipid metabolic process [inference]

glycosylceramide metabolic process [inference]

glucosylceramide metabolic process [inference]

glucosylceramide catabolic process

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

glycosphingolipid catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

glycolipid catabolic process [inference]

glycosphingolipid catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

organic substance metabolic process [inference]

carbohydrate metabolic process

lipid metabolic process [inference]

lipid catabolic process [inference]

cellular lipid catabolic process [inference]

membrane lipid catabolic process [inference]

glycolipid catabolic process [inference]

glycosphingolipid catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

sphingolipid catabolic process [inference]

glycosphingolipid catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

ceramide catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

cellular lipid metabolic process [inference]

membrane lipid metabolic process [inference]

glycolipid metabolic process [inference]

glycosphingolipid metabolic process [inference]

glycosylceramide metabolic process [inference]

glucosylceramide metabolic process [inference]

glucosylceramide catabolic process

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

glycosphingolipid catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

glycolipid catabolic process [inference]

glycosphingolipid catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

sphingolipid metabolic process [inference]

ceramide metabolic process [inference]

glycosylceramide metabolic process [inference]

glucosylceramide metabolic process [inference]

glucosylceramide catabolic process

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

ceramide catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

glycosphingolipid metabolic process [inference]

glycosylceramide metabolic process [inference]

glucosylceramide metabolic process [inference]

glucosylceramide catabolic process

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

glycosphingolipid catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

sphingolipid catabolic process [inference]

glycosphingolipid catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

ceramide catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

membrane lipid catabolic process [inference]

glycolipid catabolic process [inference]

glycosphingolipid catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

sphingolipid catabolic process [inference]

glycosphingolipid catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

ceramide catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

cellular lipid catabolic process [inference]

membrane lipid catabolic process [inference]

glycolipid catabolic process [inference]

glycosphingolipid catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

sphingolipid catabolic process [inference]

glycosphingolipid catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

ceramide catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

liposaccharide metabolic process [inference]

glycolipid metabolic process [inference]

glycosphingolipid metabolic process [inference]

glycosylceramide metabolic process [inference]

glucosylceramide metabolic process [inference]

glucosylceramide catabolic process

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

glycosphingolipid catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

glycolipid catabolic process [inference]

glycosphingolipid catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

carbohydrate derivative metabolic process [inference]

carbohydrate derivative catabolic process [inference]

glycolipid catabolic process [inference]

glycosphingolipid catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

liposaccharide metabolic process [inference]

glycolipid metabolic process [inference]

glycosphingolipid metabolic process [inference]

glycosylceramide metabolic process [inference]

glucosylceramide metabolic process [inference]

glucosylceramide catabolic process

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

glycosphingolipid catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

glycolipid catabolic process [inference]

glycosphingolipid catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

organonitrogen compound metabolic process [inference]

sphingolipid metabolic process [inference]

ceramide metabolic process [inference]

glycosylceramide metabolic process [inference]

glucosylceramide metabolic process [inference]

glucosylceramide catabolic process

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

ceramide catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

glycosphingolipid metabolic process [inference]

glycosylceramide metabolic process [inference]

glucosylceramide metabolic process [inference]

glucosylceramide catabolic process

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

glycosphingolipid catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

sphingolipid catabolic process [inference]

glycosphingolipid catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

ceramide catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

organonitrogen compound catabolic process [inference]

sphingolipid catabolic process [inference]

glycosphingolipid catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

ceramide catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

organic substance catabolic process [inference]

lipid catabolic process [inference]

cellular lipid catabolic process [inference]

membrane lipid catabolic process [inference]

glycolipid catabolic process [inference]

glycosphingolipid catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

sphingolipid catabolic process [inference]

glycosphingolipid catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

ceramide catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

carbohydrate derivative catabolic process [inference]

glycolipid catabolic process [inference]

glycosphingolipid catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

organonitrogen compound catabolic process [inference]

sphingolipid catabolic process [inference]

glycosphingolipid catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

ceramide catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

cellular process [inference]

cellular metabolic process [inference]

cellular catabolic process [inference]

cellular lipid catabolic process [inference]

membrane lipid catabolic process [inference]

glycolipid catabolic process [inference]

glycosphingolipid catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

sphingolipid catabolic process [inference]

glycosphingolipid catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

ceramide catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

cellular lipid metabolic process [inference]

membrane lipid metabolic process [inference]

glycolipid metabolic process [inference]

glycosphingolipid metabolic process [inference]

glycosylceramide metabolic process [inference]

glucosylceramide metabolic process [inference]

glucosylceramide catabolic process

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

glycosphingolipid catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

glycolipid catabolic process [inference]

glycosphingolipid catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

sphingolipid metabolic process [inference]

ceramide metabolic process [inference]

glycosylceramide metabolic process [inference]

glucosylceramide metabolic process [inference]

glucosylceramide catabolic process

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

ceramide catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

glycosphingolipid metabolic process [inference]

glycosylceramide metabolic process [inference]

glucosylceramide metabolic process [inference]

glucosylceramide catabolic process

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

glycosphingolipid catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

sphingolipid catabolic process [inference]

glycosphingolipid catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

ceramide catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

membrane lipid catabolic process [inference]

glycolipid catabolic process [inference]

glycosphingolipid catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

sphingolipid catabolic process [inference]

glycosphingolipid catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

ceramide catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

cellular lipid catabolic process [inference]

membrane lipid catabolic process [inference]

glycolipid catabolic process [inference]

glycosphingolipid catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

sphingolipid catabolic process [inference]

glycosphingolipid catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

ceramide catabolic process [inference]

glycosylceramide catabolic process [inference]

glucosylceramide catabolic process

developmental process [inference]

anatomical structure development [inference]

system development [inference]

central nervous system development

Displaying 1 entry
GO Term	Evidence Code	PMID
membrane	IEA	22301074

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane

Displaying **all 2** entries
GO Term	Evidence Code	PMID
glucosylceramidase activity	IEA	22301074
beta-glucosidase activity	IEA	30032202

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on glycosyl bonds [inference]

hydrolase activity, hydrolyzing O-glycosyl compounds [inference]

glucosylceramidase activity

glucosidase activity [inference]

beta-glucosidase activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Non-lysosomal glucosylceramidase

Functional Category

G: Carbohydrate transport and metabolism
J: Translation, ribosomal structure and biogenesis

Displaying **all 6** entries
Gene Ontology
central nervous system development
glucosylceramidase activity
glucosylceramide catabolic process
hydrolase activity, acting on glycosyl bonds
hydrolase activity
lipid metabolic process

Displaying **all 5** entries
InterPro
Beta-glucosidase GBA2-type
Glycosyl-hydrolase family 116, N-terminal
Glycosyl-hydrolase family 116, catalytic region
Six-hairpin glycosidase superfamily
Six-hairpin glycosidase-like superfamily

KEGG BRITE Database

Orthology

K17108

Name

non-lysosomal glucosylceramidase [EC:3.2.1.45]

References

Rhea

H₂O + a β-D-glucosyl-(1↔1ʼ)-N-acylsphing-4-enine

D-glucose + an N-acylsphing-4-enine

Enzyme

3.2.1.45

PMID

LIPID MAPS Gene / Proteome Database

LMPD ID: LMP014131
Gene Name: glucosidase, beta (bile acid) 2

Ortholog

Displaying entries **1 - 10** of 88 in total

1

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Last »
Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Homo sapiens	57704		HUMAN96944
Mus musculus	230101		MOUSE42874
Rattus norvegicus	298399		RATNO34208
Danio rerio	559240		DANRE41185
Monodelphis domestica	100028038		MONDO30306
Equus caballus	100067772		HORSE23976
Ornithorhynchus anatinus	100084636		ORNAN19002
Bos taurus	100139170		BOVIN34541
Sus scrofa	100155655		PIGXX15698
Taeniopygia guttata	100218507		TAEGU30863

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GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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GlyCosmos Portal v4.4.0

Last updated: December 8, 2025