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MIRAGE
leptin
Summary
- Gene Symbol
-
- LEP
- Organism
- Macaca mulatta (Rhesus monkey)
Annotation
- Keyword
-
- Disulfide bond
- Obesity
- Reference proteome
- Secreted
- Signal
- Proteins
| UniProt | Protein Name |
|---|---|
| Q28504 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| negative regulation of transcription by RNA polymerase II |
|
|
| angiogenesis |
|
|
| placenta development |
|
|
| regulation of endothelial cell proliferation |
|
|
| response to dietary excess |
|
GO Hierarchy
- regulation of cell cycle
biological process
metabolic process [inference]
cellular process [inference]
response to stimulus [inference]
localization [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of immune system process [inference]
regulation of metabolic process [inference]
regulation of biosynthetic process [inference]
positive regulation of biosynthetic process [inference]
regulation of cellular biosynthetic process [inference]
negative regulation of metabolic process [inference]
positive regulation of metabolic process [inference]
regulation of cellular metabolic process [inference]
regulation of nucleobase-containing compound metabolic process [inference]
positive regulation of cellular metabolic process [inference]
regulation of cellular biosynthetic process [inference]
regulation of phosphorus metabolic process [inference]
regulation of nitrogen compound metabolic process [inference]
regulation of macromolecule metabolic process [inference]
regulation of primary metabolic process [inference]
regulation of signaling [inference]
regulation of localization [inference]
positive regulation of biological process [inference]
positive regulation of metabolic process [inference]
positive regulation of cellular process [inference]
negative regulation of biological process [inference]
regulation of response to stimulus [inference]
regulation of cellular process [inference]
regulation of cell communication [inference]
regulation of cellular metabolic process [inference]
regulation of nucleobase-containing compound metabolic process [inference]
positive regulation of cellular metabolic process [inference]
regulation of cellular biosynthetic process [inference]
regulation of phosphorus metabolic process [inference]
regulation of cell population proliferation [inference]
positive regulation of cellular process [inference]
negative regulation of cellular process [inference]
regulation of cell activation [inference]
regulation of cellular localization [inference]
regulation of multicellular organismal process [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| extracellular region | ||
| extracellular space | ||
| cytoplasm |
|
| GO Term | Evidence Code | PMID |
|---|---|---|
| DNA binding |
|
|
| hormone activity | ||
| peptide hormone receptor binding | ||
| leptin receptor binding |
|
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- Leptin
- Functional Category
-
- G: Carbohydrate transport and metabolism
- L: Replication, recombination and repair
- T: Signal transduction mechanisms
| InterPro |
|---|
| Four-helical cytokine-like, core |
| Leptin |
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 3952 | HUMAN91180 | ||
| 16846 | MOUSE49858 | ||
| 25608 | RATNO29808 | ||
| 280836 | BOVIN28376 | ||
| 396832 | PIGXX12627 | ||
| 449638 | PANTR41327 | ||
| 493838 | FELCA03850 | ||
| 100008747 | RABIT11455 | ||
| 100014695 | MONDO33905 | ||
| 100078019 | ORNAN00888 |
