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BUB1 mitotic checkpoint serine/threonine kinase

Summary

Gene Symbol

BUB1

Organism

Homo sapiens (human)

External Links

NCBI Gene

699

PubChem

699

Alliance of Genome Resources

HGNC:1148

JoGo

BUB1

TogoVar

BUB1

Annotation

Keyword

3D-structure
ATP-binding
Alternative splicing
Apoptosis
Centromere
Chromosome
Chromosome partition
Host-virus interaction
Intellectual disability
Kinetochore
Mitosis
Nucleus
Phosphoprotein
Primary microcephaly
Proteomics identification
Reference proteome
Serine/threonine-protein kinase
Ubl conjugation

Proteins

Displaying **all 2** entries
UniProt	Protein Name
B4DYG2	BUB1A
O43683	BUB1A

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **6 - 10** of 11 in total

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GO Term	Evidence Code	PMID
mitotic spindle assembly checkpoint signaling	IMP	18995837
mitotic spindle assembly checkpoint signaling	IBA
cell division	IEA
meiotic sister chromatid cohesion, centromeric	IBA
regulation of chromosome segregation	IMP	19487456

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein phosphorylation

cellular metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phosphorylation [inference]

protein phosphorylation

primary metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein phosphorylation

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein phosphorylation

macromolecule modification [inference]

protein modification process [inference]

protein phosphorylation

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein phosphorylation

cellular process [inference]

signal transduction [inference]

intracellular signal transduction [inference]

cell cycle checkpoint signaling [inference]

mitotic cell cycle checkpoint signaling [inference]

mitotic spindle checkpoint signaling [inference]

mitotic spindle assembly checkpoint signaling

spindle checkpoint signaling [inference]

spindle assembly checkpoint signaling [inference]

mitotic spindle assembly checkpoint signaling

mitotic spindle checkpoint signaling [inference]

mitotic spindle assembly checkpoint signaling

cell death [inference]

programmed cell death [inference]

apoptotic process

cell cycle process [inference]

chromosome segregation

sister chromatid cohesion [inference]

meiotic sister chromatid cohesion [inference]

meiotic sister chromatid cohesion, centromeric

centromeric sister chromatid cohesion [inference]

meiotic sister chromatid cohesion, centromeric

mitotic cell cycle process [inference]

mitotic cell cycle checkpoint signaling [inference]

mitotic spindle checkpoint signaling [inference]

mitotic spindle assembly checkpoint signaling

cellular metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phosphorylation [inference]

protein phosphorylation

cell division

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

chromosome organization [inference]

sister chromatid cohesion [inference]

meiotic sister chromatid cohesion [inference]

meiotic sister chromatid cohesion, centromeric

centromeric sister chromatid cohesion [inference]

meiotic sister chromatid cohesion, centromeric

protein-containing complex organization [inference]

protein-DNA complex organization [inference]

chromatin organization [inference]

chromatin remodeling

biological regulation [inference]

regulation of biological process [inference]

positive regulation of biological process [inference]

positive regulation of cellular process [inference]

positive regulation of cell cycle [inference]

positive regulation of cell cycle process [inference]

positive regulation of sister chromatid cohesion [inference]

positive regulation of maintenance of sister chromatid cohesion [inference]

positive regulation of maintenance of mitotic sister chromatid cohesion [inference]

positive regulation of maintenance of mitotic sister chromatid cohesion, centromeric

positive regulation of cellular component organization [inference]

positive regulation of organelle organization [inference]

positive regulation of chromosome organization [inference]

positive regulation of sister chromatid cohesion [inference]

positive regulation of maintenance of sister chromatid cohesion [inference]

positive regulation of maintenance of mitotic sister chromatid cohesion [inference]

positive regulation of maintenance of mitotic sister chromatid cohesion, centromeric

negative regulation of biological process [inference]

negative regulation of cellular process [inference]

negative regulation of cell cycle [inference]

negative regulation of cell cycle process [inference]

negative regulation of mitotic nuclear division [inference]

negative regulation of mitotic metaphase/anaphase transition [inference]

mitotic spindle assembly checkpoint signaling

negative regulation of chromosome segregation [inference]

negative regulation of sister chromatid segregation [inference]

negative regulation of mitotic sister chromatid segregation [inference]

negative regulation of mitotic sister chromatid separation [inference]

negative regulation of mitotic metaphase/anaphase transition [inference]

mitotic spindle assembly checkpoint signaling

negative regulation of chromosome separation [inference]

negative regulation of mitotic sister chromatid separation [inference]

negative regulation of mitotic metaphase/anaphase transition [inference]

mitotic spindle assembly checkpoint signaling

negative regulation of cell cycle phase transition [inference]

cell cycle checkpoint signaling [inference]

mitotic cell cycle checkpoint signaling [inference]

mitotic spindle checkpoint signaling [inference]

mitotic spindle assembly checkpoint signaling

spindle checkpoint signaling [inference]

spindle assembly checkpoint signaling [inference]

mitotic spindle assembly checkpoint signaling

mitotic spindle checkpoint signaling [inference]

mitotic spindle assembly checkpoint signaling

negative regulation of mitotic cell cycle phase transition [inference]

negative regulation of mitotic metaphase/anaphase transition [inference]

mitotic spindle assembly checkpoint signaling

negative regulation of metaphase/anaphase transition of cell cycle [inference]

negative regulation of mitotic metaphase/anaphase transition [inference]

mitotic spindle assembly checkpoint signaling

negative regulation of mitotic cell cycle [inference]

mitotic cell cycle checkpoint signaling [inference]

mitotic spindle checkpoint signaling [inference]

mitotic spindle assembly checkpoint signaling

negative regulation of mitotic nuclear division [inference]

negative regulation of mitotic metaphase/anaphase transition [inference]

mitotic spindle assembly checkpoint signaling

negative regulation of mitotic cell cycle phase transition [inference]

negative regulation of mitotic metaphase/anaphase transition [inference]

mitotic spindle assembly checkpoint signaling

negative regulation of cellular component organization [inference]

negative regulation of organelle organization [inference]

negative regulation of nuclear division [inference]

negative regulation of mitotic nuclear division [inference]

negative regulation of mitotic metaphase/anaphase transition [inference]

mitotic spindle assembly checkpoint signaling

negative regulation of chromosome organization [inference]

negative regulation of sister chromatid segregation [inference]

negative regulation of mitotic sister chromatid segregation [inference]

negative regulation of mitotic sister chromatid separation [inference]

negative regulation of mitotic metaphase/anaphase transition [inference]

mitotic spindle assembly checkpoint signaling

regulation of cellular process [inference]

signal transduction [inference]

intracellular signal transduction [inference]

cell cycle checkpoint signaling [inference]

mitotic cell cycle checkpoint signaling [inference]

mitotic spindle checkpoint signaling [inference]

mitotic spindle assembly checkpoint signaling

spindle checkpoint signaling [inference]

spindle assembly checkpoint signaling [inference]

mitotic spindle assembly checkpoint signaling

mitotic spindle checkpoint signaling [inference]

mitotic spindle assembly checkpoint signaling

positive regulation of cellular process [inference]

positive regulation of cell cycle [inference]

positive regulation of cell cycle process [inference]

positive regulation of sister chromatid cohesion [inference]

positive regulation of maintenance of sister chromatid cohesion [inference]

positive regulation of maintenance of mitotic sister chromatid cohesion [inference]

positive regulation of maintenance of mitotic sister chromatid cohesion, centromeric

positive regulation of cellular component organization [inference]

positive regulation of organelle organization [inference]

positive regulation of chromosome organization [inference]

positive regulation of sister chromatid cohesion [inference]

positive regulation of maintenance of sister chromatid cohesion [inference]

positive regulation of maintenance of mitotic sister chromatid cohesion [inference]

positive regulation of maintenance of mitotic sister chromatid cohesion, centromeric

negative regulation of cellular process [inference]

negative regulation of cell cycle [inference]

negative regulation of cell cycle process [inference]

negative regulation of mitotic nuclear division [inference]

negative regulation of mitotic metaphase/anaphase transition [inference]

mitotic spindle assembly checkpoint signaling

negative regulation of chromosome segregation [inference]

negative regulation of sister chromatid segregation [inference]

negative regulation of mitotic sister chromatid segregation [inference]

negative regulation of mitotic sister chromatid separation [inference]

negative regulation of mitotic metaphase/anaphase transition [inference]

mitotic spindle assembly checkpoint signaling

negative regulation of chromosome separation [inference]

negative regulation of mitotic sister chromatid separation [inference]

negative regulation of mitotic metaphase/anaphase transition [inference]

mitotic spindle assembly checkpoint signaling

negative regulation of cell cycle phase transition [inference]

cell cycle checkpoint signaling [inference]

mitotic cell cycle checkpoint signaling [inference]

mitotic spindle checkpoint signaling [inference]

mitotic spindle assembly checkpoint signaling

spindle checkpoint signaling [inference]

spindle assembly checkpoint signaling [inference]

mitotic spindle assembly checkpoint signaling

mitotic spindle checkpoint signaling [inference]

mitotic spindle assembly checkpoint signaling

negative regulation of mitotic cell cycle phase transition [inference]

negative regulation of mitotic metaphase/anaphase transition [inference]

mitotic spindle assembly checkpoint signaling

negative regulation of metaphase/anaphase transition of cell cycle [inference]

negative regulation of mitotic metaphase/anaphase transition [inference]

mitotic spindle assembly checkpoint signaling

negative regulation of mitotic cell cycle [inference]

mitotic cell cycle checkpoint signaling [inference]

mitotic spindle checkpoint signaling [inference]

mitotic spindle assembly checkpoint signaling

negative regulation of mitotic nuclear division [inference]

negative regulation of mitotic metaphase/anaphase transition [inference]

mitotic spindle assembly checkpoint signaling

negative regulation of mitotic cell cycle phase transition [inference]

negative regulation of mitotic metaphase/anaphase transition [inference]

mitotic spindle assembly checkpoint signaling

negative regulation of cellular component organization [inference]

negative regulation of organelle organization [inference]

negative regulation of nuclear division [inference]

negative regulation of mitotic nuclear division [inference]

negative regulation of mitotic metaphase/anaphase transition [inference]

mitotic spindle assembly checkpoint signaling

negative regulation of chromosome organization [inference]

negative regulation of sister chromatid segregation [inference]

negative regulation of mitotic sister chromatid segregation [inference]

negative regulation of mitotic sister chromatid separation [inference]

negative regulation of mitotic metaphase/anaphase transition [inference]

mitotic spindle assembly checkpoint signaling

regulation of cellular component organization [inference]

regulation of organelle organization [inference]

positive regulation of organelle organization [inference]

positive regulation of chromosome organization [inference]

positive regulation of sister chromatid cohesion [inference]

positive regulation of maintenance of sister chromatid cohesion [inference]

positive regulation of maintenance of mitotic sister chromatid cohesion [inference]

positive regulation of maintenance of mitotic sister chromatid cohesion, centromeric

negative regulation of organelle organization [inference]

negative regulation of nuclear division [inference]

negative regulation of mitotic nuclear division [inference]

negative regulation of mitotic metaphase/anaphase transition [inference]

mitotic spindle assembly checkpoint signaling

negative regulation of chromosome organization [inference]

negative regulation of sister chromatid segregation [inference]

negative regulation of mitotic sister chromatid segregation [inference]

negative regulation of mitotic sister chromatid separation [inference]

negative regulation of mitotic metaphase/anaphase transition [inference]

mitotic spindle assembly checkpoint signaling

regulation of chromosome organization [inference]

regulation of sister chromatid cohesion

regulation of maintenance of sister chromatid cohesion [inference]

positive regulation of maintenance of sister chromatid cohesion [inference]

positive regulation of maintenance of mitotic sister chromatid cohesion [inference]

positive regulation of maintenance of mitotic sister chromatid cohesion, centromeric

regulation of maintenance of mitotic sister chromatid cohesion [inference]

positive regulation of maintenance of mitotic sister chromatid cohesion [inference]

positive regulation of maintenance of mitotic sister chromatid cohesion, centromeric

regulation of maintenance of mitotic sister chromatid cohesion, centromeric [inference]

positive regulation of maintenance of mitotic sister chromatid cohesion, centromeric

positive regulation of sister chromatid cohesion [inference]

positive regulation of maintenance of sister chromatid cohesion [inference]

positive regulation of maintenance of mitotic sister chromatid cohesion [inference]

positive regulation of maintenance of mitotic sister chromatid cohesion, centromeric

regulation of centromeric sister chromatid cohesion [inference]

regulation of maintenance of mitotic sister chromatid cohesion, centromeric [inference]

positive regulation of maintenance of mitotic sister chromatid cohesion, centromeric

regulation of sister chromatid segregation [inference]

negative regulation of sister chromatid segregation [inference]

negative regulation of mitotic sister chromatid segregation [inference]

negative regulation of mitotic sister chromatid separation [inference]

negative regulation of mitotic metaphase/anaphase transition [inference]

mitotic spindle assembly checkpoint signaling

regulation of mitotic sister chromatid segregation [inference]

negative regulation of mitotic sister chromatid segregation [inference]

negative regulation of mitotic sister chromatid separation [inference]

negative regulation of mitotic metaphase/anaphase transition [inference]

mitotic spindle assembly checkpoint signaling

regulation of metaphase/anaphase transition of cell cycle [inference]

regulation of mitotic metaphase/anaphase transition [inference]

negative regulation of mitotic metaphase/anaphase transition [inference]

mitotic spindle assembly checkpoint signaling

negative regulation of metaphase/anaphase transition of cell cycle [inference]

negative regulation of mitotic metaphase/anaphase transition [inference]

mitotic spindle assembly checkpoint signaling

negative regulation of chromosome organization [inference]

negative regulation of sister chromatid segregation [inference]

negative regulation of mitotic sister chromatid segregation [inference]

negative regulation of mitotic sister chromatid separation [inference]

negative regulation of mitotic metaphase/anaphase transition [inference]

mitotic spindle assembly checkpoint signaling

positive regulation of chromosome organization [inference]

positive regulation of sister chromatid cohesion [inference]

positive regulation of maintenance of sister chromatid cohesion [inference]

positive regulation of maintenance of mitotic sister chromatid cohesion [inference]

positive regulation of maintenance of mitotic sister chromatid cohesion, centromeric

regulation of nuclear division [inference]

regulation of mitotic nuclear division [inference]

negative regulation of mitotic nuclear division [inference]

negative regulation of mitotic metaphase/anaphase transition [inference]

mitotic spindle assembly checkpoint signaling

negative regulation of nuclear division [inference]

negative regulation of mitotic nuclear division [inference]

negative regulation of mitotic metaphase/anaphase transition [inference]

mitotic spindle assembly checkpoint signaling

negative regulation of cellular component organization [inference]

negative regulation of organelle organization [inference]

negative regulation of nuclear division [inference]

negative regulation of mitotic nuclear division [inference]

negative regulation of mitotic metaphase/anaphase transition [inference]

mitotic spindle assembly checkpoint signaling

negative regulation of chromosome organization [inference]

negative regulation of sister chromatid segregation [inference]

negative regulation of mitotic sister chromatid segregation [inference]

negative regulation of mitotic sister chromatid separation [inference]

negative regulation of mitotic metaphase/anaphase transition [inference]

mitotic spindle assembly checkpoint signaling

positive regulation of cellular component organization [inference]

positive regulation of organelle organization [inference]

positive regulation of chromosome organization [inference]

positive regulation of sister chromatid cohesion [inference]

positive regulation of maintenance of sister chromatid cohesion [inference]

positive regulation of maintenance of mitotic sister chromatid cohesion [inference]

positive regulation of maintenance of mitotic sister chromatid cohesion, centromeric

regulation of cell cycle [inference]

regulation of mitotic cell cycle [inference]

regulation of mitotic nuclear division [inference]

negative regulation of mitotic nuclear division [inference]

negative regulation of mitotic metaphase/anaphase transition [inference]

mitotic spindle assembly checkpoint signaling

negative regulation of mitotic cell cycle [inference]

mitotic cell cycle checkpoint signaling [inference]

mitotic spindle checkpoint signaling [inference]

mitotic spindle assembly checkpoint signaling

negative regulation of mitotic nuclear division [inference]

negative regulation of mitotic metaphase/anaphase transition [inference]

mitotic spindle assembly checkpoint signaling

negative regulation of mitotic cell cycle phase transition [inference]

negative regulation of mitotic metaphase/anaphase transition [inference]

mitotic spindle assembly checkpoint signaling

regulation of mitotic cell cycle phase transition [inference]

regulation of mitotic metaphase/anaphase transition [inference]

negative regulation of mitotic metaphase/anaphase transition [inference]

mitotic spindle assembly checkpoint signaling

negative regulation of mitotic cell cycle phase transition [inference]

negative regulation of mitotic metaphase/anaphase transition [inference]

mitotic spindle assembly checkpoint signaling

regulation of cell cycle process [inference]

regulation of sister chromatid cohesion

regulation of maintenance of sister chromatid cohesion [inference]

positive regulation of maintenance of sister chromatid cohesion [inference]

positive regulation of maintenance of mitotic sister chromatid cohesion [inference]

positive regulation of maintenance of mitotic sister chromatid cohesion, centromeric

regulation of maintenance of mitotic sister chromatid cohesion [inference]

positive regulation of maintenance of mitotic sister chromatid cohesion [inference]

positive regulation of maintenance of mitotic sister chromatid cohesion, centromeric

regulation of maintenance of mitotic sister chromatid cohesion, centromeric [inference]

positive regulation of maintenance of mitotic sister chromatid cohesion, centromeric

positive regulation of sister chromatid cohesion [inference]

positive regulation of maintenance of sister chromatid cohesion [inference]

positive regulation of maintenance of mitotic sister chromatid cohesion [inference]

positive regulation of maintenance of mitotic sister chromatid cohesion, centromeric

regulation of centromeric sister chromatid cohesion [inference]

regulation of maintenance of mitotic sister chromatid cohesion, centromeric [inference]

positive regulation of maintenance of mitotic sister chromatid cohesion, centromeric

regulation of mitotic nuclear division [inference]

negative regulation of mitotic nuclear division [inference]

negative regulation of mitotic metaphase/anaphase transition [inference]

mitotic spindle assembly checkpoint signaling

negative regulation of cell cycle process [inference]

negative regulation of mitotic nuclear division [inference]

negative regulation of mitotic metaphase/anaphase transition [inference]

mitotic spindle assembly checkpoint signaling

negative regulation of chromosome segregation [inference]

negative regulation of sister chromatid segregation [inference]

negative regulation of mitotic sister chromatid segregation [inference]

negative regulation of mitotic sister chromatid separation [inference]

negative regulation of mitotic metaphase/anaphase transition [inference]

mitotic spindle assembly checkpoint signaling

negative regulation of chromosome separation [inference]

negative regulation of mitotic sister chromatid separation [inference]

negative regulation of mitotic metaphase/anaphase transition [inference]

mitotic spindle assembly checkpoint signaling

negative regulation of cell cycle phase transition [inference]

cell cycle checkpoint signaling [inference]

mitotic cell cycle checkpoint signaling [inference]

mitotic spindle checkpoint signaling [inference]

mitotic spindle assembly checkpoint signaling

spindle checkpoint signaling [inference]

spindle assembly checkpoint signaling [inference]

mitotic spindle assembly checkpoint signaling

mitotic spindle checkpoint signaling [inference]

mitotic spindle assembly checkpoint signaling

negative regulation of mitotic cell cycle phase transition [inference]

negative regulation of mitotic metaphase/anaphase transition [inference]

mitotic spindle assembly checkpoint signaling

negative regulation of metaphase/anaphase transition of cell cycle [inference]

negative regulation of mitotic metaphase/anaphase transition [inference]

mitotic spindle assembly checkpoint signaling

regulation of chromosome segregation

regulation of sister chromatid segregation [inference]

negative regulation of sister chromatid segregation [inference]

negative regulation of mitotic sister chromatid segregation [inference]

negative regulation of mitotic sister chromatid separation [inference]

negative regulation of mitotic metaphase/anaphase transition [inference]

mitotic spindle assembly checkpoint signaling

regulation of mitotic sister chromatid segregation [inference]

negative regulation of mitotic sister chromatid segregation [inference]

negative regulation of mitotic sister chromatid separation [inference]

negative regulation of mitotic metaphase/anaphase transition [inference]

mitotic spindle assembly checkpoint signaling

regulation of metaphase/anaphase transition of cell cycle [inference]

regulation of mitotic metaphase/anaphase transition [inference]

negative regulation of mitotic metaphase/anaphase transition [inference]

mitotic spindle assembly checkpoint signaling

negative regulation of metaphase/anaphase transition of cell cycle [inference]

negative regulation of mitotic metaphase/anaphase transition [inference]

mitotic spindle assembly checkpoint signaling

negative regulation of chromosome segregation [inference]

negative regulation of sister chromatid segregation [inference]

negative regulation of mitotic sister chromatid segregation [inference]

negative regulation of mitotic sister chromatid separation [inference]

negative regulation of mitotic metaphase/anaphase transition [inference]

mitotic spindle assembly checkpoint signaling

negative regulation of chromosome separation [inference]

negative regulation of mitotic sister chromatid separation [inference]

negative regulation of mitotic metaphase/anaphase transition [inference]

mitotic spindle assembly checkpoint signaling

regulation of chromosome separation [inference]

regulation of mitotic sister chromatid separation [inference]

negative regulation of mitotic sister chromatid separation [inference]

negative regulation of mitotic metaphase/anaphase transition [inference]

mitotic spindle assembly checkpoint signaling

negative regulation of chromosome separation [inference]

negative regulation of mitotic sister chromatid separation [inference]

negative regulation of mitotic metaphase/anaphase transition [inference]

mitotic spindle assembly checkpoint signaling

positive regulation of cell cycle process [inference]

positive regulation of sister chromatid cohesion [inference]

positive regulation of maintenance of sister chromatid cohesion [inference]

positive regulation of maintenance of mitotic sister chromatid cohesion [inference]

positive regulation of maintenance of mitotic sister chromatid cohesion, centromeric

regulation of cell cycle phase transition [inference]

negative regulation of cell cycle phase transition [inference]

cell cycle checkpoint signaling [inference]

mitotic cell cycle checkpoint signaling [inference]

mitotic spindle checkpoint signaling [inference]

mitotic spindle assembly checkpoint signaling

spindle checkpoint signaling [inference]

spindle assembly checkpoint signaling [inference]

mitotic spindle assembly checkpoint signaling

mitotic spindle checkpoint signaling [inference]

mitotic spindle assembly checkpoint signaling

negative regulation of mitotic cell cycle phase transition [inference]

negative regulation of mitotic metaphase/anaphase transition [inference]

mitotic spindle assembly checkpoint signaling

negative regulation of metaphase/anaphase transition of cell cycle [inference]

negative regulation of mitotic metaphase/anaphase transition [inference]

mitotic spindle assembly checkpoint signaling

regulation of mitotic cell cycle phase transition [inference]

regulation of mitotic metaphase/anaphase transition [inference]

negative regulation of mitotic metaphase/anaphase transition [inference]

mitotic spindle assembly checkpoint signaling

negative regulation of mitotic cell cycle phase transition [inference]

negative regulation of mitotic metaphase/anaphase transition [inference]

mitotic spindle assembly checkpoint signaling

regulation of metaphase/anaphase transition of cell cycle [inference]

regulation of mitotic metaphase/anaphase transition [inference]

negative regulation of mitotic metaphase/anaphase transition [inference]

mitotic spindle assembly checkpoint signaling

negative regulation of metaphase/anaphase transition of cell cycle [inference]

negative regulation of mitotic metaphase/anaphase transition [inference]

mitotic spindle assembly checkpoint signaling

negative regulation of cell cycle [inference]

negative regulation of cell cycle process [inference]

negative regulation of mitotic nuclear division [inference]

negative regulation of mitotic metaphase/anaphase transition [inference]

mitotic spindle assembly checkpoint signaling

negative regulation of chromosome segregation [inference]

negative regulation of sister chromatid segregation [inference]

negative regulation of mitotic sister chromatid segregation [inference]

negative regulation of mitotic sister chromatid separation [inference]

negative regulation of mitotic metaphase/anaphase transition [inference]

mitotic spindle assembly checkpoint signaling

negative regulation of chromosome separation [inference]

negative regulation of mitotic sister chromatid separation [inference]

negative regulation of mitotic metaphase/anaphase transition [inference]

mitotic spindle assembly checkpoint signaling

negative regulation of cell cycle phase transition [inference]

cell cycle checkpoint signaling [inference]

mitotic cell cycle checkpoint signaling [inference]

mitotic spindle checkpoint signaling [inference]

mitotic spindle assembly checkpoint signaling

spindle checkpoint signaling [inference]

spindle assembly checkpoint signaling [inference]

mitotic spindle assembly checkpoint signaling

mitotic spindle checkpoint signaling [inference]

mitotic spindle assembly checkpoint signaling

negative regulation of mitotic cell cycle phase transition [inference]

negative regulation of mitotic metaphase/anaphase transition [inference]

mitotic spindle assembly checkpoint signaling

negative regulation of metaphase/anaphase transition of cell cycle [inference]

negative regulation of mitotic metaphase/anaphase transition [inference]

mitotic spindle assembly checkpoint signaling

negative regulation of mitotic cell cycle [inference]

mitotic cell cycle checkpoint signaling [inference]

mitotic spindle checkpoint signaling [inference]

mitotic spindle assembly checkpoint signaling

negative regulation of mitotic nuclear division [inference]

negative regulation of mitotic metaphase/anaphase transition [inference]

mitotic spindle assembly checkpoint signaling

negative regulation of mitotic cell cycle phase transition [inference]

negative regulation of mitotic metaphase/anaphase transition [inference]

mitotic spindle assembly checkpoint signaling

positive regulation of cell cycle [inference]

positive regulation of cell cycle process [inference]

positive regulation of sister chromatid cohesion [inference]

positive regulation of maintenance of sister chromatid cohesion [inference]

positive regulation of maintenance of mitotic sister chromatid cohesion [inference]

positive regulation of maintenance of mitotic sister chromatid cohesion, centromeric

Displaying entries **6 - 9** of 9 in total

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GO Term	Evidence Code	PMID
cytosol	TAS
cytosol	IDA
membrane	HDA	19946888
intracellular membrane-bounded organelle	IDA

GO Hierarchy

cellular component

protein-containing complex [inference]

outer kinetochore

cellular anatomical entity [inference]

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle

nucleus

non-membrane-bounded organelle [inference]

intracellular non-membrane-bounded organelle [inference]

kinetochore

intracellular organelle [inference]

intracellular membrane-bounded organelle

nucleus

intracellular non-membrane-bounded organelle [inference]

kinetochore

supramolecular complex [inference]

kinetochore

Displaying entries **1 - 5** of 28 in total

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GO Term	Evidence Code	PMID
protein kinase activity	IDA	18995837 22331848
protein kinase activity	IMP	22331848
protein kinase activity	IBA
protein serine/threonine kinase activity	IDA	25308863 26658523 30429199
3-phosphoinositide-dependent protein kinase activity	IEA

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

transferase activity, transferring phosphorus-containing groups [inference]

kinase activity [inference]

protein kinase activity

protein serine/threonine kinase activity

histone kinase activity [inference]

histone H2A kinase activity

histone H3 kinase activity [inference]

histone H4 kinase activity [inference]

histone H4S1 kinase activity

histone H2B kinase activity [inference]

histone H2AX kinase activity [inference]

histone H2AXS139 kinase activity

protein serine kinase activity

phosphotransferase activity, alcohol group as acceptor [inference]

protein kinase activity

protein serine/threonine kinase activity

histone kinase activity [inference]

histone H2A kinase activity

histone H3 kinase activity [inference]

histone H4 kinase activity [inference]

histone H4S1 kinase activity

histone H2B kinase activity [inference]

histone H2AX kinase activity [inference]

histone H2AXS139 kinase activity

protein serine kinase activity

catalytic activity, acting on a protein [inference]

protein kinase activity

protein serine/threonine kinase activity

histone kinase activity [inference]

histone H2A kinase activity

histone H3 kinase activity [inference]

histone H4 kinase activity [inference]

histone H4S1 kinase activity

histone H2B kinase activity [inference]

histone H2AX kinase activity [inference]

histone H2AXS139 kinase activity

protein serine kinase activity

histone modifying activity [inference]

histone kinase activity [inference]

histone H2A kinase activity

histone H3 kinase activity [inference]

histone H4 kinase activity [inference]

histone H4S1 kinase activity

histone H2B kinase activity [inference]

histone H2AX kinase activity [inference]

histone H2AXS139 kinase activity

binding [inference]

protein binding

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ion binding [inference]

anion binding [inference]

purine ribonucleoside triphosphate binding [inference]

ATP binding

organic cyclic compound binding [inference]

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Kinase

Functional Category

C: Energy production and conversion
Q: Secondary metabolites biosynthesis, transport and catabolism
T: Signal transduction mechanisms

Displaying **all 5** entries
Gene Ontology
ATP binding
kinase activity
meiotic sister chromatid cohesion, centromeric
nucleotide binding
phosphorylation

Displaying **all 6** entries
InterPro
Mad3/Bub1 homology region 1
Mitotic spindle checkpoint protein Bub1/Mad3
Protein kinase domain
Protein kinase, ATP binding site
Protein kinase-like domain superfamily
Serine/threonine-protein kinase, active site

Disease

Disease Ontology

Displaying **all 2** entries
DO ID	Disease Name	Source
DOID:0070296	primary autosomal recessive microcephaly	Alliance of Genome Resources
DOID:9256	colorectal cancer	Alliance of Genome Resources

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

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Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements