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telomerase associated protein 1

Summary

Gene Symbol

TEP1

Organism

Homo sapiens (human)

External Links

NCBI Gene

7011

PubChem

7011

Alliance of Genome Resources

HGNC:11726

JoGo

TEP1

TogoVar

TEP1

Annotation

Keyword

ATP-binding
Alternative splicing
Nucleus
Proteomics identification
RNA-binding
Reference proteome
Repeat
Ribonucleoprotein
Telomere
WD repeat

Proteins

Displaying **all 2** entries
UniProt	Protein Name
G3V5X7	Telomerase-associated protein 1 p240 p80 telomerase homolog
Q99973	Telomerase-associated protein 1 p240 p80 telomerase homolog

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 3** entries
GO Term	Evidence Code	PMID
telomere maintenance via recombination	IDA	10810353
telomere maintenance via recombination	IBA
RNA-templated DNA biosynthetic process	IEA

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process [inference]

RNA-templated DNA biosynthetic process

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

telomere maintenance [inference]

telomere maintenance via recombination

DNA recombination [inference]

mitotic recombination [inference]

telomere maintenance via recombination

DNA biosynthetic process [inference]

RNA-templated DNA biosynthetic process

cellular nitrogen compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process [inference]

RNA-templated DNA biosynthetic process

biosynthetic process [inference]

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

DNA biosynthetic process [inference]

RNA-templated DNA biosynthetic process

heterocycle biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process [inference]

RNA-templated DNA biosynthetic process

aromatic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process [inference]

RNA-templated DNA biosynthetic process

cellular nitrogen compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process [inference]

RNA-templated DNA biosynthetic process

organic substance biosynthetic process [inference]

macromolecule biosynthetic process [inference]

DNA biosynthetic process [inference]

RNA-templated DNA biosynthetic process

organic cyclic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process [inference]

RNA-templated DNA biosynthetic process

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process [inference]

RNA-templated DNA biosynthetic process

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

telomere maintenance [inference]

telomere maintenance via recombination

DNA recombination [inference]

mitotic recombination [inference]

telomere maintenance via recombination

DNA biosynthetic process [inference]

RNA-templated DNA biosynthetic process

aromatic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process [inference]

RNA-templated DNA biosynthetic process

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process [inference]

RNA-templated DNA biosynthetic process

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

telomere maintenance [inference]

telomere maintenance via recombination

DNA recombination [inference]

mitotic recombination [inference]

telomere maintenance via recombination

DNA biosynthetic process [inference]

RNA-templated DNA biosynthetic process

cellular nitrogen compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process [inference]

RNA-templated DNA biosynthetic process

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

DNA biosynthetic process [inference]

RNA-templated DNA biosynthetic process

heterocycle biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process [inference]

RNA-templated DNA biosynthetic process

aromatic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process [inference]

RNA-templated DNA biosynthetic process

cellular nitrogen compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process [inference]

RNA-templated DNA biosynthetic process

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process [inference]

RNA-templated DNA biosynthetic process

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

telomere maintenance [inference]

telomere maintenance via recombination

DNA recombination [inference]

mitotic recombination [inference]

telomere maintenance via recombination

DNA biosynthetic process [inference]

RNA-templated DNA biosynthetic process

heterocycle biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process [inference]

RNA-templated DNA biosynthetic process

primary metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process [inference]

RNA-templated DNA biosynthetic process

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

telomere maintenance [inference]

telomere maintenance via recombination

DNA recombination [inference]

mitotic recombination [inference]

telomere maintenance via recombination

DNA biosynthetic process [inference]

RNA-templated DNA biosynthetic process

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

macromolecule biosynthetic process [inference]

DNA biosynthetic process [inference]

RNA-templated DNA biosynthetic process

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

telomere maintenance [inference]

telomere maintenance via recombination

DNA recombination [inference]

mitotic recombination [inference]

telomere maintenance via recombination

DNA biosynthetic process [inference]

RNA-templated DNA biosynthetic process

organic cyclic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process [inference]

RNA-templated DNA biosynthetic process

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

telomere maintenance [inference]

telomere maintenance via recombination

DNA recombination [inference]

mitotic recombination [inference]

telomere maintenance via recombination

DNA biosynthetic process [inference]

RNA-templated DNA biosynthetic process

organic cyclic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process [inference]

RNA-templated DNA biosynthetic process

organic substance biosynthetic process [inference]

macromolecule biosynthetic process [inference]

DNA biosynthetic process [inference]

RNA-templated DNA biosynthetic process

organic cyclic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process [inference]

RNA-templated DNA biosynthetic process

cellular process [inference]

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process [inference]

RNA-templated DNA biosynthetic process

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

telomere maintenance [inference]

telomere maintenance via recombination

DNA recombination [inference]

mitotic recombination [inference]

telomere maintenance via recombination

DNA biosynthetic process [inference]

RNA-templated DNA biosynthetic process

aromatic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process [inference]

RNA-templated DNA biosynthetic process

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process [inference]

RNA-templated DNA biosynthetic process

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

telomere maintenance [inference]

telomere maintenance via recombination

DNA recombination [inference]

mitotic recombination [inference]

telomere maintenance via recombination

DNA biosynthetic process [inference]

RNA-templated DNA biosynthetic process

cellular nitrogen compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process [inference]

RNA-templated DNA biosynthetic process

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

DNA biosynthetic process [inference]

RNA-templated DNA biosynthetic process

heterocycle biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process [inference]

RNA-templated DNA biosynthetic process

aromatic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process [inference]

RNA-templated DNA biosynthetic process

cellular nitrogen compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process [inference]

RNA-templated DNA biosynthetic process

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process [inference]

RNA-templated DNA biosynthetic process

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

telomere maintenance [inference]

telomere maintenance via recombination

DNA recombination [inference]

mitotic recombination [inference]

telomere maintenance via recombination

DNA biosynthetic process [inference]

RNA-templated DNA biosynthetic process

heterocycle biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process [inference]

RNA-templated DNA biosynthetic process

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

chromosome organization [inference]

telomere organization [inference]

telomere maintenance [inference]

telomere maintenance via recombination

Displaying entries **1 - 5** of 6 in total

1

2

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GO Term	Evidence Code	PMID
chromosome, telomeric region	IEA
telomerase holoenzyme complex	IDA	12135483
telomerase holoenzyme complex	IBA
cytoplasm	IDA	7876352
nuclear matrix	IDA	7876352

GO Hierarchy

cellular component

protein-containing complex [inference]

nuclear protein-containing complex [inference]

telomerase holoenzyme complex

catalytic complex [inference]

telomerase holoenzyme complex

ribonucleoprotein complex

telomerase holoenzyme complex

cellular anatomical entity [inference]

chromosomal region [inference]

chromosome, telomeric region

Displaying entries **1 - 5** of 9 in total

1

2

Next ›

Last »
GO Term	Evidence Code	PMID
p53 binding	IPI	10597287
telomerase activity	IDA	12135483
telomerase activity	IBA
RNA binding	ISS
protein binding	IPI	32296183

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

transferase activity, transferring phosphorus-containing groups [inference]

nucleotidyltransferase activity [inference]

DNA polymerase activity [inference]

RNA-directed DNA polymerase activity [inference]

telomerase activity

catalytic activity, acting on a nucleic acid [inference]

catalytic activity, acting on DNA [inference]

DNA polymerase activity [inference]

RNA-directed DNA polymerase activity [inference]

telomerase activity

binding [inference]

protein binding

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ion binding [inference]

anion binding [inference]

purine ribonucleoside triphosphate binding [inference]

ATP binding

organic cyclic compound binding [inference]

nucleic acid binding [inference]

RNA binding

telomerase RNA binding

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Telomerase protein 1

Functional Category

G: Carbohydrate transport and metabolism
K: Transcription
T: Signal transduction mechanisms

Displaying **all 2** entries
InterPro
Domain of unknown function DUF4062
P-loop containing nucleoside triphosphate hydrolase

Disease

Disease Ontology

Displaying **all 2** entries
DO ID	Disease Name	Source
DOID:10534	stomach cancer	Alliance of Genome Resources
DOID:684	hepatocellular carcinoma	Alliance of Genome Resources

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

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Guidelines

Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements