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solute carrier family 44, member 4

Summary

Gene Symbol

Slc44a4

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

70129

PubChem

70129

Alliance of Genome Resources

MGI:1917379

Annotation

Keyword

Antiport
Cell membrane
Glycoprotein
Reference proteome
Transmembrane helix

Proteins

Displaying **all 3** entries
UniProt	Protein Name
Q91VA1	Solute carrier family 44 member 4 Thiamine pyrophosphate transporter 1
Q3TL93
Q3ULA4

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 7 in total

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GO Term	Evidence Code	PMID
acetylcholine secretion	ISO ISS
otolith formation	ISS
thiamine pyrophosphate transmembrane transport	IBA IDA ISO	24379411
neuromast hair cell development	ISS
positive regulation of cell growth	ISO ISS

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

acetylcholine metabolic process [inference]

acetylcholine biosynthetic process

organonitrogen compound biosynthetic process [inference]

acetylcholine biosynthetic process

biosynthetic process [inference]

organic substance biosynthetic process [inference]

acetate ester biosynthetic process [inference]

acetylcholine biosynthetic process

organonitrogen compound biosynthetic process [inference]

acetylcholine biosynthetic process

organic substance metabolic process [inference]

acetate ester metabolic process [inference]

acetylcholine metabolic process [inference]

acetylcholine biosynthetic process

acetate ester biosynthetic process [inference]

acetylcholine biosynthetic process

organonitrogen compound metabolic process [inference]

acetylcholine metabolic process [inference]

acetylcholine biosynthetic process

organonitrogen compound biosynthetic process [inference]

acetylcholine biosynthetic process

organic substance biosynthetic process [inference]

acetate ester biosynthetic process [inference]

acetylcholine biosynthetic process

organonitrogen compound biosynthetic process [inference]

acetylcholine biosynthetic process

cellular process [inference]

cellular developmental process [inference]

cell development [inference]

neuron development [inference]

neuromast hair cell development

transmembrane transport [inference]

vitamin transmembrane transport [inference]

thiamine transmembrane transport [inference]

thiamine pyrophosphate transmembrane transport

azole transmembrane transport [inference]

thiamine transmembrane transport [inference]

thiamine pyrophosphate transmembrane transport

pyrimidine-containing compound transmembrane transport [inference]

thiamine transmembrane transport [inference]

thiamine pyrophosphate transmembrane transport

export from cell [inference]

secretion by cell [inference]

signal release [inference]

acetylcholine secretion

developmental process [inference]

anatomical structure formation involved in morphogenesis [inference]

otolith formation

anatomical structure development [inference]

cell development [inference]

neuron development [inference]

neuromast hair cell development

cellular developmental process [inference]

cell development [inference]

neuron development [inference]

neuromast hair cell development

localization [inference]

establishment of localization [inference]

transport [inference]

secretion [inference]

secretion by cell [inference]

signal release [inference]

acetylcholine secretion

vitamin transport [inference]

thiamine transport [inference]

thiamine transmembrane transport [inference]

thiamine pyrophosphate transmembrane transport

vitamin transmembrane transport [inference]

thiamine transmembrane transport [inference]

thiamine pyrophosphate transmembrane transport

transmembrane transport [inference]

vitamin transmembrane transport [inference]

thiamine transmembrane transport [inference]

thiamine pyrophosphate transmembrane transport

azole transmembrane transport [inference]

thiamine transmembrane transport [inference]

thiamine pyrophosphate transmembrane transport

pyrimidine-containing compound transmembrane transport [inference]

thiamine transmembrane transport [inference]

thiamine pyrophosphate transmembrane transport

organic substance transport [inference]

organic cation transport [inference]

acetylcholine transport [inference]

acetylcholine secretion

choline transport

thiamine transport [inference]

thiamine transmembrane transport [inference]

thiamine pyrophosphate transmembrane transport

quaternary ammonium group transport [inference]

acetylcholine transport [inference]

acetylcholine secretion

organic anion transport [inference]

thiamine pyrophosphate transmembrane transport

organophosphate ester transport [inference]

thiamine pyrophosphate transmembrane transport

azole transmembrane transport [inference]

thiamine transmembrane transport [inference]

thiamine pyrophosphate transmembrane transport

pyrimidine-containing compound transmembrane transport [inference]

thiamine transmembrane transport [inference]

thiamine pyrophosphate transmembrane transport

acetate ester transport [inference]

acetylcholine transport [inference]

acetylcholine secretion

nitrogen compound transport [inference]

quaternary ammonium group transport [inference]

acetylcholine transport [inference]

acetylcholine secretion

thiamine transport [inference]

thiamine transmembrane transport [inference]

thiamine pyrophosphate transmembrane transport

azole transmembrane transport [inference]

thiamine transmembrane transport [inference]

thiamine pyrophosphate transmembrane transport

pyrimidine-containing compound transmembrane transport [inference]

thiamine transmembrane transport [inference]

thiamine pyrophosphate transmembrane transport

sulfur compound transport [inference]

thiamine transport [inference]

thiamine transmembrane transport [inference]

thiamine pyrophosphate transmembrane transport

export from cell [inference]

secretion by cell [inference]

signal release [inference]

acetylcholine secretion

biological regulation [inference]

regulation of biological process [inference]

regulation of growth [inference]

regulation of cell growth [inference]

positive regulation of cell growth

positive regulation of growth [inference]

positive regulation of cell growth

positive regulation of biological process [inference]

positive regulation of growth [inference]

positive regulation of cell growth

positive regulation of cellular process [inference]

positive regulation of cell growth

regulation of cellular process [inference]

positive regulation of cellular process [inference]

positive regulation of cell growth

regulation of cellular component organization [inference]

regulation of cell growth [inference]

positive regulation of cell growth

Displaying **all 2** entries
GO Term	Evidence Code	PMID
apical plasma membrane	ISO ISS
plasma membrane	IBA ISO

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

plasma membrane region [inference]

apical plasma membrane

Displaying **all 4** entries
GO Term	Evidence Code	PMID
thiamine pyrophosphate transmembrane transporter activity	IBA IDA ISO	24379411
choline transmembrane transporter activity	ISO ISS
antiporter activity	IEA
organic cation transmembrane transporter activity

GO Hierarchy

molecular function

transporter activity [inference]

transmembrane transporter activity [inference]

organic anion transmembrane transporter activity [inference]

thiamine pyrophosphate transmembrane transporter activity

organic cation transmembrane transporter activity

thiamine transmembrane transporter activity [inference]

thiamine pyrophosphate transmembrane transporter activity

quaternary ammonium group transmembrane transporter activity [inference]

organophosphate ester transmembrane transporter activity [inference]

thiamine pyrophosphate transmembrane transporter activity

active transmembrane transporter activity [inference]

secondary active transmembrane transporter activity [inference]

antiporter activity

vitamin transmembrane transporter activity [inference]

thiamine transmembrane transporter activity [inference]

thiamine pyrophosphate transmembrane transporter activity

azole transmembrane transporter activity [inference]

thiamine transmembrane transporter activity [inference]

thiamine pyrophosphate transmembrane transporter activity

sulfur compound transmembrane transporter activity [inference]

thiamine transmembrane transporter activity [inference]

thiamine pyrophosphate transmembrane transporter activity

salt transmembrane transporter activity [inference]

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Rodentia

Group Name

Choline transporter-like

Functional Category

K: Transcription
T: Signal transduction mechanisms

Displaying **all 3** entries
Gene Ontology
choline transport
salt transmembrane transporter activity
thiamine pyrophosphate transmembrane transporter activity

Displaying 1 entry
InterPro
Choline transporter-like

Disease

Disease Ontology

Displaying **all 2** entries
DO ID	Disease Name	Source
DOID:0080268	autosomal dominant nonsyndromic deafness 72	Alliance of Genome Resources
DOID:10003	sensorineural hearing loss	Alliance of Genome Resources

Ortholog

Displaying entries **1 - 10** of 97 in total

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Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Drosophila melanogaster	43440		FB:FBgn0039637
Homo sapiens	80736		HGNC:13941	HUMAN84065
Caenorhabditis elegans	180809		WB:WBGene00018037
Rattus norvegicus	294255	10116_1:005201	RGD:1303167	RATNO22468
Danio rerio	393385		ZFIN:ZDB-GENE-040426-1371
Pan troglodytes	462571			PANTR37747
Canis lupus familiaris	481718			CANLF02572
Bos taurus	520625			BOVIN18754
Macaca mulatta	715779			MACMU35160
Monodelphis domestica	100025341			MONDO11353