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vacuolar protein sorting 36

Summary

Gene Symbol

Vps36

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

70160

PubChem

70160

Alliance of Genome Resources

MGI:1917410

Annotation

Keyword

3D-structure
Coiled coil
Cytoplasm
Endosome
Lipid-binding
Membrane
Nucleus
Protein transport
Reference proteome
Transcription regulation

Proteins

Displaying **all 2** entries
UniProt	Protein Name
Q3TSR1	ESCRT-II complex subunit VPS36
Q91XD6	ESCRT-II complex subunit VPS36

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 4** entries
GO Term	Evidence Code	PMID
protein transport	IEA
endosomal transport	IC	15755741
endosome transport via multivesicular body sorting pathway	IEA
protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway	IBA

GO Hierarchy

biological process

cellular process [inference]

vesicle-mediated transport [inference]

endosomal transport

endosome transport via multivesicular body sorting pathway

late endosome to vacuole transport via multivesicular body sorting pathway [inference]

protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway

late endosome to vacuole transport [inference]

late endosome to vacuole transport via multivesicular body sorting pathway [inference]

protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway

multivesicular body sorting pathway [inference]

endosome transport via multivesicular body sorting pathway

late endosome to vacuole transport via multivesicular body sorting pathway [inference]

protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway

cellular localization [inference]

intracellular transport [inference]

intracellular protein transport [inference]

protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway

vacuolar transport [inference]

late endosome to vacuole transport [inference]

late endosome to vacuole transport via multivesicular body sorting pathway [inference]

protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway

endosomal transport

endosome transport via multivesicular body sorting pathway

late endosome to vacuole transport via multivesicular body sorting pathway [inference]

protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to organelle [inference]

establishment of protein localization to organelle [inference]

establishment of protein localization to vacuole [inference]

protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway

protein localization to vacuole [inference]

establishment of protein localization to vacuole [inference]

protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway

establishment of protein localization [inference]

protein transport

intracellular protein transport [inference]

protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway

establishment of protein localization to organelle [inference]

establishment of protein localization to vacuole [inference]

protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway

localization [inference]

macromolecule localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to organelle [inference]

establishment of protein localization to organelle [inference]

establishment of protein localization to vacuole [inference]

protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway

protein localization to vacuole [inference]

establishment of protein localization to vacuole [inference]

protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway

establishment of protein localization [inference]

protein transport

intracellular protein transport [inference]

protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway

establishment of protein localization to organelle [inference]

establishment of protein localization to vacuole [inference]

protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway

establishment of localization [inference]

transport [inference]

vesicle-mediated transport [inference]

endosomal transport

endosome transport via multivesicular body sorting pathway

late endosome to vacuole transport via multivesicular body sorting pathway [inference]

protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway

late endosome to vacuole transport [inference]

late endosome to vacuole transport via multivesicular body sorting pathway [inference]

protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway

multivesicular body sorting pathway [inference]

endosome transport via multivesicular body sorting pathway

late endosome to vacuole transport via multivesicular body sorting pathway [inference]

protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway

intracellular transport [inference]

intracellular protein transport [inference]

protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway

vacuolar transport [inference]

late endosome to vacuole transport [inference]

late endosome to vacuole transport via multivesicular body sorting pathway [inference]

protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway

endosomal transport

endosome transport via multivesicular body sorting pathway

late endosome to vacuole transport via multivesicular body sorting pathway [inference]

protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway

organic substance transport [inference]

protein transport

intracellular protein transport [inference]

protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway

nitrogen compound transport [inference]

protein transport

intracellular protein transport [inference]

protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway

establishment of protein localization [inference]

protein transport

intracellular protein transport [inference]

protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway

establishment of protein localization to organelle [inference]

establishment of protein localization to vacuole [inference]

protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway

establishment of localization in cell [inference]

intracellular transport [inference]

intracellular protein transport [inference]

protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway

vacuolar transport [inference]

late endosome to vacuole transport [inference]

late endosome to vacuole transport via multivesicular body sorting pathway [inference]

protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway

endosomal transport

endosome transport via multivesicular body sorting pathway

late endosome to vacuole transport via multivesicular body sorting pathway [inference]

protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway

cellular localization [inference]

intracellular transport [inference]

intracellular protein transport [inference]

protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway

vacuolar transport [inference]

late endosome to vacuole transport [inference]

late endosome to vacuole transport via multivesicular body sorting pathway [inference]

protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway

endosomal transport

endosome transport via multivesicular body sorting pathway

late endosome to vacuole transport via multivesicular body sorting pathway [inference]

protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to organelle [inference]

establishment of protein localization to organelle [inference]

establishment of protein localization to vacuole [inference]

protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway

protein localization to vacuole [inference]

establishment of protein localization to vacuole [inference]

protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway

establishment of protein localization [inference]

protein transport

intracellular protein transport [inference]

protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway

establishment of protein localization to organelle [inference]

establishment of protein localization to vacuole [inference]

protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway

Displaying entries **1 - 5** of 12 in total

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GO Term	Evidence Code	PMID
ESCRT II complex	ISO
ESCRT II complex	IBA
ESCRT II complex	IEA
nucleus	IEA
lysosome	IDA	15755741

GO Hierarchy

cellular component

protein-containing complex [inference]

ESCRT complex [inference]

ESCRT II complex

membrane protein complex [inference]

ESCRT II complex

cellular anatomical entity [inference]

cytosol

membrane [inference]

organelle membrane [inference]

vesicle membrane [inference]

cytoplasmic vesicle membrane [inference]

endosome membrane [inference]

late endosome membrane

bounding membrane of organelle [inference]

endosome membrane [inference]

late endosome membrane

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome

late endosome

intracellular membrane-bounded organelle [inference]

nucleus

vacuole [inference]

lytic vacuole [inference]

lysosome

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome

late endosome

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

vacuole [inference]

lytic vacuole [inference]

lysosome

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome

late endosome

Displaying **all 4** entries
GO Term	Evidence Code	PMID
phosphatidylinositol-3-phosphate binding	IEA
ubiquitin binding	ISO
ubiquitin binding	IDA	15755741
ubiquitin binding	IBA

GO Hierarchy

molecular function

binding [inference]

protein binding [inference]

ubiquitin-like protein binding [inference]

ubiquitin binding

lipid binding [inference]

phospholipid binding [inference]

phosphatidylinositol binding [inference]

phosphatidylinositol phosphate binding [inference]

phosphatidylinositol-3-phosphate binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Vacuolar protein

Functional Category

E: Amino acid transport and metabolism
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 4** entries
Gene Ontology
endosome transport via multivesicular body sorting pathway
phosphatidylinositol-3-phosphate binding
protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway
ubiquitin binding

Displaying **all 6** entries
InterPro
PH-like domain superfamily
Snf8/Vps36 family
Vacuolar protein sorting protein 36, GLUE domain
Vacuolar protein sorting protein 36
Winged helix DNA-binding domain superfamily
Winged helix-like DNA-binding domain superfamily

Ortholog

Displaying entries **1 - 10** of 69 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Homo sapiens	51028		HUMAN17206
Xenopus tropicalis	70160	Xenbase:XB-GENE-954399
Rattus norvegicus	290851		RATNO11498
Pan troglodytes	452739		PANTR07836
Canis lupus familiaris	477292		CANLF09780
Bos taurus	511223		BOVIN03737
Macaca mulatta	693290		MACMU16296
Taeniopygia guttata	100224399		TAEGU11394
Oryctolagus cuniculus	100340347		RABIT14320
Pongo abelii	100457630		PONAB06739