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left-right determination factor 2
Summary
- Gene Symbol
-
- LEFTY2
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- Alternative splicing
- Cytokine
- Developmental protein
- Disease variant
- Disulfide bond
- Glycoprotein
- Growth factor
- Heterotaxy
- Reference proteome
- Secreted
- Signal
- Proteins
| UniProt | Protein Name |
|---|---|
| O00292 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| signal transduction | ||
| anterior/posterior axis specification |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| extracellular region | ||
| extracellular space | ||
| platelet alpha granule lumen | ||
| collagen-containing extracellular matrix |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| cytokine activity | ||
| transforming growth factor beta receptor binding | ||
| growth factor activity |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- left-right determination factor
- Functional Category
-
- E: Amino acid transport and metabolism
- O: Posttranslational modification, protein turnover, chaperones
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| anterior/posterior axis specification |
| cytokine activity |
| growth factor activity |
| transforming growth factor beta receptor binding |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:1682 | congenital heart disease |
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 7044 | Xenbase:XB-GENE-6258963 | ||
| 10637 | Xenbase:XB-GENE-6258963 | ||
| 13590 | Xenbase:XB-GENE-6258963 | MOUSE27850 | |
| 30145 | DANRE19247 | ||
| 30146 | DANRE12164 | ||
| 289316 | RATNO06543 | ||
| 320202 | ZFIN:ZDB-GENE-990630-10 | MOUSE27835 | |
| 457780 | PANTR23810 | ||
| 490387 | CANLF17342 | ||
| 498299 | RATNO06941 |
