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CD248 antigen, endosialin

Summary

Gene Symbol

Cd248

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

70445

PubChem

70445

Alliance of Genome Resources

MGI:1917695

Annotation

Keyword

Calcium
Disulfide bond
EGF-like domain
Glycoprotein
Lectin
Phosphoprotein
Reference proteome
Signal
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
Q91V98	Tumor endothelial marker 1

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	PMID
positive regulation of fibroblast proliferation	IMP	20432232
lymph node development	IMP	20432232
cell migration	IBA
endothelial cell apoptotic process	IMP	22740442
anatomical structure regression	IMP	22740442

GO Hierarchy

biological process

cellular process [inference]

cell death [inference]

programmed cell death [inference]

apoptotic process [inference]

epithelial cell apoptotic process [inference]

endothelial cell apoptotic process

cell population proliferation [inference]

fibroblast proliferation

cell motility [inference]

cell migration

ameboidal-type cell migration [inference]

fibroblast migration

developmental process [inference]

anatomical structure development [inference]

animal organ development [inference]

hematopoietic or lymphoid organ development [inference]

lymph node development

anatomical structure regression

biological regulation [inference]

regulation of biological process [inference]

positive regulation of biological process [inference]

positive regulation of cellular process [inference]

positive regulation of cell population proliferation [inference]

positive regulation of fibroblast proliferation

positive regulation of programmed cell death [inference]

positive regulation of apoptotic process [inference]

positive regulation of epithelial cell apoptotic process [inference]

positive regulation of endothelial cell apoptotic process

regulation of cellular process [inference]

regulation of cell population proliferation [inference]

positive regulation of cell population proliferation [inference]

positive regulation of fibroblast proliferation

regulation of fibroblast proliferation [inference]

positive regulation of fibroblast proliferation

regulation of programmed cell death [inference]

regulation of apoptotic process [inference]

positive regulation of apoptotic process [inference]

positive regulation of epithelial cell apoptotic process [inference]

positive regulation of endothelial cell apoptotic process

regulation of epithelial cell apoptotic process [inference]

positive regulation of epithelial cell apoptotic process [inference]

positive regulation of endothelial cell apoptotic process

regulation of endothelial cell apoptotic process [inference]

positive regulation of endothelial cell apoptotic process

positive regulation of programmed cell death [inference]

positive regulation of apoptotic process [inference]

positive regulation of epithelial cell apoptotic process [inference]

positive regulation of endothelial cell apoptotic process

positive regulation of cellular process [inference]

positive regulation of cell population proliferation [inference]

positive regulation of fibroblast proliferation

positive regulation of programmed cell death [inference]

positive regulation of apoptotic process [inference]

positive regulation of epithelial cell apoptotic process [inference]

positive regulation of endothelial cell apoptotic process

Displaying **all 3** entries
GO Term	Evidence Code	PMID
external side of plasma membrane	IBA
plasma membrane	ISO	11559528
cytoplasm	IDA	11489895

GO Hierarchy

cellular component

cellular anatomical entity [inference]

cytoplasm

membrane [inference]

plasma membrane

side of membrane [inference]

external side of plasma membrane

Displaying **all 4** entries
GO Term	Evidence Code	PMID
extracellular matrix binding	IBA IDA	22740442
calcium ion binding	IEA
extracellular matrix protein binding	IBA
carbohydrate binding	IEA

GO Hierarchy

molecular function

binding [inference]

protein binding [inference]

extracellular matrix protein binding

carbohydrate binding

ion binding [inference]

cation binding [inference]

metal ion binding [inference]

calcium ion binding

extracellular matrix binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Rodentia

Group Name

C-type lectin-like

Functional Category

Q: Secondary metabolites biosynthesis, transport and catabolism
T: Signal transduction mechanisms

Displaying **all 4** entries
Gene Ontology
calcium ion binding
cell migration
extracellular matrix binding
extracellular matrix protein binding

Displaying **all 7** entries
InterPro
C-type lectin fold
C-type lectin-like/link domain superfamily
C-type lectin-like
EGF-like calcium-binding domain
EGF-like calcium-binding, conserved site
EGF-like domain
Growth factor receptor cysteine-rich domain superfamily

Ortholog

Displaying entries **1 - 10** of 77 in total

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Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Homo sapiens	57124		HGNC:18219	HUMAN07362
Rattus norvegicus	293669	10116_1:00013a	RGD:1310404	RATNO15863
Danio rerio	323364		ZFIN:ZDB-GENE-030131-2084
Pan troglodytes	466674			PANTR03479
Bos taurus	520070			BOVIN23511
Macaca mulatta	714375			MACMU10222
Danio rerio	100002565		ZFIN:ZDB-GENE-050309-46
Equus caballus	100146570			HORSE05486
Callithrix jacchus	100395255			CALJA05313
Pongo abelii	100443054			PONAB03296