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ectonucleotide pyrophosphatase/phosphodiesterase 2

Summary

Gene Symbol

ENPP2

Organism

Macaca mulatta (Rhesus monkey)

External Links

NCBI Gene: 705287
KEGG Gene ID: mcc:705287
PubChem: 705287

Annotation

Keyword

Calcium
Disulfide bond
Metal-binding
Repeat
Secreted
Transmembrane helix
Zinc

Proteins

Displaying **all 2** entries
UniProt	Protein Name
I0FJB5
G7N009

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 2** entries
GO Term	Evidence Code	PMID
phosphatidylcholine catabolic process	IEA	30032202
immune response	IEA	22301074

GO Hierarchy

biological process

immune system process [inference]

immune response

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

phosphatidylcholine metabolic process [inference]

phosphatidylcholine catabolic process

organonitrogen compound catabolic process [inference]

phosphatidylcholine catabolic process

catabolic process [inference]

cellular catabolic process [inference]

cellular lipid catabolic process [inference]

phospholipid catabolic process [inference]

glycerophospholipid catabolic process [inference]

phosphatidylcholine catabolic process

glycerolipid catabolic process [inference]

glycerophospholipid catabolic process [inference]

phosphatidylcholine catabolic process

organic substance catabolic process [inference]

lipid catabolic process [inference]

cellular lipid catabolic process [inference]

phospholipid catabolic process [inference]

glycerophospholipid catabolic process [inference]

phosphatidylcholine catabolic process

glycerolipid catabolic process [inference]

glycerophospholipid catabolic process [inference]

phosphatidylcholine catabolic process

organophosphate catabolic process [inference]

phospholipid catabolic process [inference]

glycerophospholipid catabolic process [inference]

phosphatidylcholine catabolic process

organonitrogen compound catabolic process [inference]

phosphatidylcholine catabolic process

cellular metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylcholine metabolic process [inference]

phosphatidylcholine catabolic process

glycerophospholipid catabolic process [inference]

phosphatidylcholine catabolic process

phospholipid catabolic process [inference]

glycerophospholipid catabolic process [inference]

phosphatidylcholine catabolic process

organophosphate metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylcholine metabolic process [inference]

phosphatidylcholine catabolic process

glycerophospholipid catabolic process [inference]

phosphatidylcholine catabolic process

phospholipid catabolic process [inference]

glycerophospholipid catabolic process [inference]

phosphatidylcholine catabolic process

organophosphate catabolic process [inference]

phospholipid catabolic process [inference]

glycerophospholipid catabolic process [inference]

phosphatidylcholine catabolic process

cellular catabolic process [inference]

cellular lipid catabolic process [inference]

phospholipid catabolic process [inference]

glycerophospholipid catabolic process [inference]

phosphatidylcholine catabolic process

glycerolipid catabolic process [inference]

glycerophospholipid catabolic process [inference]

phosphatidylcholine catabolic process

cellular lipid metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylcholine metabolic process [inference]

phosphatidylcholine catabolic process

glycerophospholipid catabolic process [inference]

phosphatidylcholine catabolic process

phospholipid catabolic process [inference]

glycerophospholipid catabolic process [inference]

phosphatidylcholine catabolic process

cellular lipid catabolic process [inference]

phospholipid catabolic process [inference]

glycerophospholipid catabolic process [inference]

phosphatidylcholine catabolic process

glycerolipid catabolic process [inference]

glycerophospholipid catabolic process [inference]

phosphatidylcholine catabolic process

glycerolipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylcholine metabolic process [inference]

phosphatidylcholine catabolic process

glycerophospholipid catabolic process [inference]

phosphatidylcholine catabolic process

glycerolipid catabolic process [inference]

glycerophospholipid catabolic process [inference]

phosphatidylcholine catabolic process

primary metabolic process [inference]

lipid metabolic process [inference]

lipid catabolic process [inference]

cellular lipid catabolic process [inference]

phospholipid catabolic process [inference]

glycerophospholipid catabolic process [inference]

phosphatidylcholine catabolic process

glycerolipid catabolic process [inference]

glycerophospholipid catabolic process [inference]

phosphatidylcholine catabolic process

cellular lipid metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylcholine metabolic process [inference]

phosphatidylcholine catabolic process

glycerophospholipid catabolic process [inference]

phosphatidylcholine catabolic process

phospholipid catabolic process [inference]

glycerophospholipid catabolic process [inference]

phosphatidylcholine catabolic process

cellular lipid catabolic process [inference]

phospholipid catabolic process [inference]

glycerophospholipid catabolic process [inference]

phosphatidylcholine catabolic process

glycerolipid catabolic process [inference]

glycerophospholipid catabolic process [inference]

phosphatidylcholine catabolic process

glycerolipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylcholine metabolic process [inference]

phosphatidylcholine catabolic process

glycerophospholipid catabolic process [inference]

phosphatidylcholine catabolic process

glycerolipid catabolic process [inference]

glycerophospholipid catabolic process [inference]

phosphatidylcholine catabolic process

organic substance metabolic process [inference]

lipid metabolic process [inference]

lipid catabolic process [inference]

cellular lipid catabolic process [inference]

phospholipid catabolic process [inference]

glycerophospholipid catabolic process [inference]

phosphatidylcholine catabolic process

glycerolipid catabolic process [inference]

glycerophospholipid catabolic process [inference]

phosphatidylcholine catabolic process

cellular lipid metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylcholine metabolic process [inference]

phosphatidylcholine catabolic process

glycerophospholipid catabolic process [inference]

phosphatidylcholine catabolic process

phospholipid catabolic process [inference]

glycerophospholipid catabolic process [inference]

phosphatidylcholine catabolic process

cellular lipid catabolic process [inference]

phospholipid catabolic process [inference]

glycerophospholipid catabolic process [inference]

phosphatidylcholine catabolic process

glycerolipid catabolic process [inference]

glycerophospholipid catabolic process [inference]

phosphatidylcholine catabolic process

glycerolipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylcholine metabolic process [inference]

phosphatidylcholine catabolic process

glycerophospholipid catabolic process [inference]

phosphatidylcholine catabolic process

glycerolipid catabolic process [inference]

glycerophospholipid catabolic process [inference]

phosphatidylcholine catabolic process

organophosphate metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylcholine metabolic process [inference]

phosphatidylcholine catabolic process

glycerophospholipid catabolic process [inference]

phosphatidylcholine catabolic process

phospholipid catabolic process [inference]

glycerophospholipid catabolic process [inference]

phosphatidylcholine catabolic process

organophosphate catabolic process [inference]

phospholipid catabolic process [inference]

glycerophospholipid catabolic process [inference]

phosphatidylcholine catabolic process

organonitrogen compound metabolic process [inference]

phosphatidylcholine metabolic process [inference]

phosphatidylcholine catabolic process

organonitrogen compound catabolic process [inference]

phosphatidylcholine catabolic process

organic substance catabolic process [inference]

lipid catabolic process [inference]

cellular lipid catabolic process [inference]

phospholipid catabolic process [inference]

glycerophospholipid catabolic process [inference]

phosphatidylcholine catabolic process

glycerolipid catabolic process [inference]

glycerophospholipid catabolic process [inference]

phosphatidylcholine catabolic process

organophosphate catabolic process [inference]

phospholipid catabolic process [inference]

glycerophospholipid catabolic process [inference]

phosphatidylcholine catabolic process

organonitrogen compound catabolic process [inference]

phosphatidylcholine catabolic process

cellular process [inference]

cellular metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylcholine metabolic process [inference]

phosphatidylcholine catabolic process

glycerophospholipid catabolic process [inference]

phosphatidylcholine catabolic process

phospholipid catabolic process [inference]

glycerophospholipid catabolic process [inference]

phosphatidylcholine catabolic process

organophosphate metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylcholine metabolic process [inference]

phosphatidylcholine catabolic process

glycerophospholipid catabolic process [inference]

phosphatidylcholine catabolic process

phospholipid catabolic process [inference]

glycerophospholipid catabolic process [inference]

phosphatidylcholine catabolic process

organophosphate catabolic process [inference]

phospholipid catabolic process [inference]

glycerophospholipid catabolic process [inference]

phosphatidylcholine catabolic process

cellular catabolic process [inference]

cellular lipid catabolic process [inference]

phospholipid catabolic process [inference]

glycerophospholipid catabolic process [inference]

phosphatidylcholine catabolic process

glycerolipid catabolic process [inference]

glycerophospholipid catabolic process [inference]

phosphatidylcholine catabolic process

cellular lipid metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylcholine metabolic process [inference]

phosphatidylcholine catabolic process

glycerophospholipid catabolic process [inference]

phosphatidylcholine catabolic process

phospholipid catabolic process [inference]

glycerophospholipid catabolic process [inference]

phosphatidylcholine catabolic process

cellular lipid catabolic process [inference]

phospholipid catabolic process [inference]

glycerophospholipid catabolic process [inference]

phosphatidylcholine catabolic process

glycerolipid catabolic process [inference]

glycerophospholipid catabolic process [inference]

phosphatidylcholine catabolic process

glycerolipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylcholine metabolic process [inference]

phosphatidylcholine catabolic process

glycerophospholipid catabolic process [inference]

phosphatidylcholine catabolic process

glycerolipid catabolic process [inference]

glycerophospholipid catabolic process [inference]

phosphatidylcholine catabolic process

response to stimulus [inference]

immune response

Displaying 1 entry
GO Term	Evidence Code	PMID
extracellular space	IEA	30032202

GO Hierarchy

cellular component

cellular anatomical entity [inference]

extracellular space

Displaying entries **6 - 8** of 8 in total

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1

2
GO Term	Evidence Code	PMID
calcium ion binding	IEA	30032202
polysaccharide binding	IEA	22301074
lysophospholipase activity	IEA	30032202

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on ester bonds [inference]

nuclease activity [inference]

exonuclease activity [inference]

phosphodiesterase I activity

lipase activity [inference]

phospholipase activity [inference]

lysophospholipase activity

phosphoric ester hydrolase activity [inference]

phosphoric diester hydrolase activity [inference]

carboxylic ester hydrolase activity [inference]

lysophospholipase activity

binding [inference]

carbohydrate binding [inference]

polysaccharide binding

ion binding [inference]

cation binding [inference]

metal ion binding [inference]

calcium ion binding

transition metal ion binding [inference]

zinc ion binding

organic cyclic compound binding [inference]

nucleic acid binding

cargo receptor activity [inference]

scavenger receptor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

ECTONUCLEOTIDE PYROPHOSPHATASE/PHOSPHODIESTERASE

Functional Category

G: Carbohydrate transport and metabolism
O: Posttranslational modification, protein turnover, chaperones
Q: Secondary metabolites biosynthesis, transport and catabolism

Displaying 1 entry
Gene Ontology
nucleoside triphosphate diphosphatase activity

Displaying **all 2** entries
InterPro
Alkaline-phosphatase-like, core domain superfamily
Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase

Ortholog

Displaying entries **11 - 20** of 78 in total

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Last »
Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Taeniopygia guttata	100219257			TAEGU17924
Danio rerio	100332039			DANRE10115
Oryctolagus cuniculus	100348637			RABIT09929
Callithrix jacchus	100397344			CALJA13938
Ailuropoda melanoleuca	100464202			AILME02158
Meleagris gallopavo	100541506			MELGA09281
Nomascus leucogenys	100603476			NOMLE11110
Loxodonta africana	100659415			LOXAF16510
Cricetulus griseus	100755955			CRIGR08151
Sarcophilus harrisii	100930676			SARHA00388

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GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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GlyCosmos Portal v4.1.0

Last updated: December 9, 2024