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MIRAGE
TIAM Rac1 associated GEF 1
Summary
- Gene Symbol
-
- TIAM1
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Alternative splicing
- Cell junction
- Cell membrane
- Coiled coil
- Epilepsy
- Guanine-nucleotide releasing factor
- Intellectual disability
- Isopeptide bond
- Lipid-binding
- Myristate
- Phosphoprotein
- Proteomics identification
- Reference proteome
- Repeat
- Ubl conjugation
- Proteins
| UniProt | Protein Name |
|---|---|
| A0A8V8TN84 |
|
| A0A1B0GW57 |
|
| A0A2X0TW27 |
|
| Q13009 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| cardiac muscle hypertrophy | ||
| cell-matrix adhesion | ||
| small GTPase mediated signal transduction | ||
| positive regulation of cell population proliferation | ||
| regulation of epithelial to mesenchymal transition |
GO Hierarchy
biological process
biological regulation [inference]
regulation of biological process [inference]
regulation of localization [inference]
regulation of locomotion [inference]
positive regulation of biological process [inference]
regulation of developmental process [inference]
regulation of cellular process [inference]
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| guanyl-nucleotide exchange factor activity | ||
| guanyl-nucleotide exchange factor activity | ||
| guanyl-nucleotide exchange factor activity | ||
| guanyl-nucleotide exchange factor activity | ||
| guanyl-nucleotide exchange factor activity |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- pleckstrin homology
- Functional Category
-
- E: Amino acid transport and metabolism
- O: Posttranslational modification, protein turnover, chaperones
- T: Signal transduction mechanisms
| InterPro |
|---|
| Dbl homology (DH) domain superfamily |
| Dbl homology (DH) domain |
| PH-like domain superfamily |
| Pleckstrin homology domain |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0070444 | neurodevelopmental disorder with language delay and seizures |
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 7074 | Xenbase:XB-GENE-1006478 | ||
| 21844 | MOUSE17501 | ||
| 24001 | FB:FBgn0085447 | ||
| 26230 | FB:FBgn0085447 | ||
| 304109 | RATNO04299 | ||
| 473949 | PANTR25541 | ||
| 487731 | CANLF12807 | ||
| 702288 | MACMU31129 | ||
| 100015064 | MONDO20801 | ||
| 100052764 | HORSE24578 |
