tumor protein p53

Summary
Gene Symbol
  • TP53
Organism
Homo sapiens (human)
External Links
NCBI Gene
7157
PubChem
7157
Alliance of Genome Resources
Annotation
Keyword
  • 3D-structure
  • Acetylation
  • Activator
  • Alternative promoter usage
  • Alternative splicing
  • Apoptosis
  • Biological rhythms
  • Cell cycle
  • Cytoplasm
  • Cytoskeleton
  • DNA-binding
  • Direct protein sequencing
  • Disease variant
  • Endoplasmic reticulum
  • Glycoprotein
  • Host-virus interaction
  • Isopeptide bond
  • Li-Fraumeni syndrome
  • Metal-binding
  • Methylation
  • Mitochondrion
  • Necrosis
  • Nucleus
  • Phosphoprotein
  • Proteomics identification
  • Reference proteome
  • Repressor
  • Transcription regulation
  • Tumor suppressor
  • Ubl conjugation
  • Zinc
Proteins
Displaying all 7 entries
UniProt Protein Name
A0A087WT22
H2EHT1
A0A087WXZ1
P04637
  • Antigen NY-CO-13
  • Phosphoprotein p53
  • Tumor suppressor p53
K7PPA8
A0A087X1Q1
Q53GA5
  • Tumor suppressor p53
Gene Ontology (GO)
GO Hierarchy
Displaying entries 26 - 30 of 35 in total
GO Term Evidence Code PMID
molecular function activator activity
protein binding
transcription cis-regulatory region binding
RNA polymerase II cis-regulatory region sequence-specific DNA binding
protease binding
GO Hierarchy
Disease
Disease Ontology
Displaying entries 1 - 10 of 79 in total
DO ID Disease Name Source
DOID:0001816 angiosarcoma
DOID:0002116 pterygium
DOID:0050745 diffuse large B-cell lymphoma
DOID:0050834 CHARGE syndrome
DOID:0050861 colorectal adenocarcinoma
DOID:0050865 tongue squamous cell carcinoma
DOID:0050866 oral squamous cell carcinoma
DOID:0050902 medulloblastoma
DOID:0050908 myelodysplastic syndrome
DOID:0060071 pre-malignant neoplasm
Ortholog
Displaying entries 61 - 62 of 62 in total
Species Gene ID Alliance of Genome Resources Orthologous MAtrix
103752115 NANGA01862
103264637 CARSF10741

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: August 19, 2024