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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
triosephosphate isomerase 1
Summary
- Gene Symbol
-
- TPI1
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Acetylation
- Alternative promoter usage
- Alternative splicing
- Cytoplasm
- Direct protein sequencing
- Disease variant
- Gluconeogenesis
- Glycolysis
- Hereditary hemolytic anemia
- Isomerase
- Isopeptide bond
- Lyase
- Methylation
- Nitration
- Phosphoprotein
- Reference proteome
- Ubl conjugation
- Proteins
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| gluconeogenesis |
GO Hierarchy
biological process
metabolic process [inference]
nitrogen compound metabolic process [inference]
cellular nitrogen compound metabolic process [inference]
nucleobase-containing compound metabolic process [inference]
cellular nitrogen compound catabolic process [inference]
purine-containing compound metabolic process [inference]
organonitrogen compound metabolic process [inference]
catabolic process [inference]
cellular catabolic process [inference]
aromatic compound catabolic process [inference]
cellular nitrogen compound catabolic process [inference]
heterocycle catabolic process [inference]
organic substance catabolic process [inference]
biosynthetic process [inference]
cellular metabolic process [inference]
cellular aromatic compound metabolic process [inference]
nucleobase-containing compound metabolic process [inference]
aromatic compound catabolic process [inference]
phosphorus metabolic process [inference]
phosphate-containing compound metabolic process [inference]
organophosphate metabolic process [inference]
cellular nitrogen compound metabolic process [inference]
nucleobase-containing compound metabolic process [inference]
cellular nitrogen compound catabolic process [inference]
purine-containing compound metabolic process [inference]
cellular catabolic process [inference]
aromatic compound catabolic process [inference]
cellular nitrogen compound catabolic process [inference]
heterocycle catabolic process [inference]
heterocycle metabolic process [inference]
nucleobase-containing compound metabolic process [inference]
heterocycle catabolic process [inference]
purine-containing compound metabolic process [inference]
primary metabolic process [inference]
carbohydrate metabolic process [inference]
nucleobase-containing compound metabolic process [inference]
small molecule metabolic process [inference]
organic substance metabolic process [inference]
carbohydrate metabolic process [inference]
organophosphate metabolic process [inference]
carbohydrate derivative metabolic process [inference]
organic cyclic compound metabolic process [inference]
nucleobase-containing compound metabolic process [inference]
purine-containing compound metabolic process [inference]
organic cyclic compound catabolic process [inference]
organonitrogen compound metabolic process [inference]
organic substance catabolic process [inference]
cellular process [inference]
cellular metabolic process [inference]
cellular aromatic compound metabolic process [inference]
nucleobase-containing compound metabolic process [inference]
aromatic compound catabolic process [inference]
phosphorus metabolic process [inference]
phosphate-containing compound metabolic process [inference]
organophosphate metabolic process [inference]
cellular nitrogen compound metabolic process [inference]
nucleobase-containing compound metabolic process [inference]
cellular nitrogen compound catabolic process [inference]
purine-containing compound metabolic process [inference]
cellular catabolic process [inference]
aromatic compound catabolic process [inference]
cellular nitrogen compound catabolic process [inference]
heterocycle catabolic process [inference]
heterocycle metabolic process [inference]
nucleobase-containing compound metabolic process [inference]
heterocycle catabolic process [inference]
purine-containing compound metabolic process [inference]
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| protein homodimerization activity | ||
| triose-phosphate isomerase activity | ||
| ubiquitin protein ligase binding | ||
| methylglyoxal synthase activity | ||
| protein binding |
GO Hierarchy
KEGG BRITE Database
Rhea
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0014667 | disease of metabolism | |
| DOID:0050486 | exanthem | |
| DOID:0050635 | alternating hemiplegia of childhood | |
| DOID:0050700 | cardiomyopathy | |
| DOID:0050757 | deafness-dystonia-optic neuronopathy syndrome | |
| DOID:0050865 | tongue squamous cell carcinoma | |
| DOID:0050884 | triosephosphate isomerase deficiency | |
| DOID:0060041 | autism spectrum disorder | |
| DOID:0080199 | colorectal carcinoma | |
| DOID:0080326 | familial hypertrophic cardiomyopathy |
- The Human Phenotype Ontology
| HPO ID | HPO Term |
|---|---|
| HP:0001290 | Generalized hypotonia |
| HP:0001324 | Muscle weakness |
| HP:0001332 | Dystonia |
| HP:0001337 | Tremor |
| HP:0001508 | Failure to thrive |
| HP:0001522 | Death in infancy |
| HP:0001562 | Oligohydramnios |
| HP:0001635 | Congestive heart failure |
| HP:0001639 | Hypertrophic cardiomyopathy |
| HP:0001744 | Splenomegaly |
| Disease ID | Disease Name |
|---|---|
| ORPHA:868 |
|
| OMIM:615512 |
|
PubChem Disease
- GHR Health Conditions
- MedGen Diseases
- OMIM Phenotypes
- KEGG Diseases
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 114587774 | PODMU23882 | ||
| 107549487 | SINGR69888 | ||
| 106847322 | EQUAS05657 | ||
| 116837582 | CHEAB23298 | ||
| 105295948 | PTEVA01703 | ||
| 115044805 | ECHNA27493 | ||
| 115397033 | SALFA31673 | ||
| 851620 | SGD:S000002457 | ||
| 109048699 | CYPCA34698 | ||
| 109104501 | CYPCA60306 |
