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Guidelines

MIRAGE

sterol O-acyltransferase 1

Summary

Gene Symbol

SOAT1

Organism

Macaca mulatta (Rhesus monkey)

External Links

NCBI Gene: 716989
KEGG Gene ID: mcc:716989
PubChem: 716989

Annotation

Keyword

Acyltransferase
Cholesterol metabolism
Disulfide bond
Endoplasmic reticulum
Phosphoprotein
Reference proteome
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
A0A1D5QIZ8

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 3** entries
GO Term	Evidence Code	PMID
cholesterol metabolic process	IEA	30032202
cholesterol efflux	IEA	30032202
cholesterol homeostasis	IEA	22301074

GO Hierarchy

biological process

metabolic process [inference]

primary metabolic process [inference]

lipid metabolic process [inference]

steroid metabolic process [inference]

sterol metabolic process [inference]

cholesterol metabolic process

small molecule metabolic process [inference]

alcohol metabolic process [inference]

secondary alcohol metabolic process [inference]

cholesterol metabolic process

organic substance metabolic process [inference]

lipid metabolic process [inference]

steroid metabolic process [inference]

sterol metabolic process [inference]

cholesterol metabolic process

organic cyclic compound metabolic process [inference]

steroid metabolic process [inference]

sterol metabolic process [inference]

cholesterol metabolic process

organic hydroxy compound metabolic process [inference]

alcohol metabolic process [inference]

secondary alcohol metabolic process [inference]

cholesterol metabolic process

sterol metabolic process [inference]

cholesterol metabolic process

homeostatic process [inference]

chemical homeostasis [inference]

lipid homeostasis [inference]

sterol homeostasis [inference]

cholesterol homeostasis

localization [inference]

establishment of localization [inference]

transport [inference]

organic substance transport [inference]

lipid transport [inference]

sterol transport [inference]

cholesterol transport [inference]

cholesterol efflux

organic hydroxy compound transport [inference]

sterol transport [inference]

cholesterol transport [inference]

cholesterol efflux

Displaying 1 entry
GO Term	Evidence Code	PMID
endoplasmic reticulum membrane	IEA	30032202

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

organelle membrane [inference]

endoplasmic reticulum membrane

Displaying **all 3** entries
GO Term	Evidence Code	PMID
fatty-acyl-CoA binding	IEA	30032202
cholesterol binding	IEA	30032202
cholesterol O-acyltransferase activity	IEA	22301074 30032202

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

acyltransferase activity [inference]

acyltransferase activity, transferring groups other than amino-acyl groups [inference]

O-acyltransferase activity [inference]

sterol O-acyltransferase activity [inference]

cholesterol O-acyltransferase activity

binding [inference]

lipid binding [inference]

steroid binding [inference]

sterol binding [inference]

cholesterol binding

fatty acid derivative binding [inference]

fatty-acyl-CoA binding

amide binding [inference]

acyl-CoA binding [inference]

fatty-acyl-CoA binding

small molecule binding [inference]

alcohol binding [inference]

cholesterol binding

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

acyl-CoA binding [inference]

fatty-acyl-CoA binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

acyl-CoA binding [inference]

fatty-acyl-CoA binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

acyl-CoA binding [inference]

fatty-acyl-CoA binding

ion binding [inference]

anion binding [inference]

acyl-CoA binding [inference]

fatty-acyl-CoA binding

organic cyclic compound binding [inference]

steroid binding [inference]

sterol binding [inference]

cholesterol binding

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

acyl-CoA binding [inference]

fatty-acyl-CoA binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

acyl-CoA binding [inference]

fatty-acyl-CoA binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

acyl-CoA binding [inference]

fatty-acyl-CoA binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

acyl-CoA binding [inference]

fatty-acyl-CoA binding

sulfur compound binding [inference]

acyl-CoA binding [inference]

fatty-acyl-CoA binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

O-acyltransferase

Functional Category

M: Cell wall/membrane/envelope biogenesis
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 7** entries
Gene Ontology
O-acyltransferase activity
cholesterol O-acyltransferase activity
cholesterol binding
cholesterol efflux
cholesterol metabolic process
fatty-acyl-CoA binding
transferase activity

Displaying **all 2** entries
InterPro
Membrane bound O-acyl transferase, MBOAT
Sterol O-acyltransferase, ACAT/DAG/ARE types

LIPID MAPS Gene / Proteome Database

LMPD ID: LMP014886
Gene Name: sterol O-acyltransferase 1-like

Ortholog

Displaying entries **1 - 10** of 75 in total

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Last »
Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Homo sapiens	6646		HUMAN53728
Mus musculus	20652		MOUSE27769
Pan troglodytes	457553		PANTR23126
Canis lupus familiaris	490325		CANLF17205
Bos taurus	504287		BOVIN08700
Danio rerio	564424		DANRE42487
Oryctolagus cuniculus	100009537		RABIT03017
Equus caballus	100050551		HORSE34749
Ornithorhynchus anatinus	100085367		ORNAN07821
Taeniopygia guttata	100223763		TAEGU29514

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Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: December 8, 2025