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regulator of G-protein signaling 12

Summary

Gene Symbol

Rgs12

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

71729

PubChem

71729

Alliance of Genome Resources

MGI:1918979

Annotation

Keyword

Cell projection
Cytoplasm
GTPase activation
Isopeptide bond
Methylation
Nucleus
Phosphoprotein
Proteomics identification
Reference proteome
Repeat
Synapse
Ubl conjugation

Proteins

Displaying **all 8** entries
UniProt	Protein Name
D3Z0G5
E9Q1K7
D3Z0G6
Q3TTW9
Q8BPL6
E9Q652
Q9D677
Q8CGE9

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 4** entries
GO Term	Evidence Code	PMID
signal transduction	IEA
regulation of G protein-coupled receptor signaling pathway	IBA
negative regulation of signal transduction	IEA
termination of G protein-coupled receptor signaling pathway	ISO

GO Hierarchy

biological process

cellular process [inference]

signal transduction

biological regulation [inference]

regulation of biological process [inference]

regulation of signaling [inference]

regulation of signal transduction [inference]

regulation of G protein-coupled receptor signaling pathway

negative regulation of G protein-coupled receptor signaling pathway [inference]

termination of G protein-coupled receptor signaling pathway

negative regulation of signal transduction

termination of signal transduction [inference]

termination of G protein-coupled receptor signaling pathway

negative regulation of G protein-coupled receptor signaling pathway [inference]

termination of G protein-coupled receptor signaling pathway

negative regulation of signaling [inference]

negative regulation of signal transduction

termination of signal transduction [inference]

termination of G protein-coupled receptor signaling pathway

negative regulation of G protein-coupled receptor signaling pathway [inference]

termination of G protein-coupled receptor signaling pathway

negative regulation of biological process [inference]

negative regulation of signaling [inference]

negative regulation of signal transduction

termination of signal transduction [inference]

termination of G protein-coupled receptor signaling pathway

negative regulation of G protein-coupled receptor signaling pathway [inference]

termination of G protein-coupled receptor signaling pathway

negative regulation of cellular process [inference]

negative regulation of cell communication [inference]

negative regulation of signal transduction

termination of signal transduction [inference]

termination of G protein-coupled receptor signaling pathway

negative regulation of G protein-coupled receptor signaling pathway [inference]

termination of G protein-coupled receptor signaling pathway

negative regulation of response to stimulus [inference]

negative regulation of signal transduction

termination of signal transduction [inference]

termination of G protein-coupled receptor signaling pathway

negative regulation of G protein-coupled receptor signaling pathway [inference]

termination of G protein-coupled receptor signaling pathway

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

regulation of G protein-coupled receptor signaling pathway

negative regulation of G protein-coupled receptor signaling pathway [inference]

termination of G protein-coupled receptor signaling pathway

negative regulation of signal transduction

termination of signal transduction [inference]

termination of G protein-coupled receptor signaling pathway

negative regulation of G protein-coupled receptor signaling pathway [inference]

termination of G protein-coupled receptor signaling pathway

negative regulation of response to stimulus [inference]

negative regulation of signal transduction

termination of signal transduction [inference]

termination of G protein-coupled receptor signaling pathway

negative regulation of G protein-coupled receptor signaling pathway [inference]

termination of G protein-coupled receptor signaling pathway

regulation of cellular process [inference]

signal transduction

regulation of cell communication [inference]

regulation of signal transduction [inference]

regulation of G protein-coupled receptor signaling pathway

negative regulation of G protein-coupled receptor signaling pathway [inference]

termination of G protein-coupled receptor signaling pathway

negative regulation of signal transduction

termination of signal transduction [inference]

termination of G protein-coupled receptor signaling pathway

negative regulation of G protein-coupled receptor signaling pathway [inference]

termination of G protein-coupled receptor signaling pathway

negative regulation of cell communication [inference]

negative regulation of signal transduction

termination of signal transduction [inference]

termination of G protein-coupled receptor signaling pathway

negative regulation of G protein-coupled receptor signaling pathway [inference]

termination of G protein-coupled receptor signaling pathway

negative regulation of cellular process [inference]

negative regulation of cell communication [inference]

negative regulation of signal transduction

termination of signal transduction [inference]

termination of G protein-coupled receptor signaling pathway

negative regulation of G protein-coupled receptor signaling pathway [inference]

termination of G protein-coupled receptor signaling pathway

Displaying entries **1 - 5** of 17 in total

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GO Term	Evidence Code	PMID
nucleus	ISS
nucleus	ISO
nucleus	IBA
nucleoplasm	ISO
nucleolus	ISO

GO Hierarchy

cellular component

protein-containing complex

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

cell junction [inference]

synapse

cell projection [inference]

plasma membrane bounded cell projection [inference]

neuron projection [inference]

dendrite

apical dendrite

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

non-membrane-bounded organelle [inference]

intracellular non-membrane-bounded organelle [inference]

nucleolus

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

intracellular non-membrane-bounded organelle [inference]

nucleolus

cell body [inference]

neuronal cell body

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
G-protein alpha-subunit binding	ISO
GTPase activator activity	ISO
GTPase activator activity	IBA
GTPase activator activity	IEA
protein binding	IPI	17380122

GO Hierarchy

molecular function

binding [inference]

protein binding

G-protein alpha-subunit binding

molecular function regulator activity [inference]

enzyme regulator activity [inference]

enzyme activator activity [inference]

GTPase activator activity

nucleoside-triphosphatase regulator activity [inference]

GTPase regulator activity

GTPase activator activity

molecular function activator activity [inference]

enzyme activator activity [inference]

GTPase activator activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

regulator of G-protein signaling

Functional Category

E: Amino acid transport and metabolism
J: Translation, ribosomal structure and biogenesis
P: Inorganic ion transport and metabolism

Displaying 1 entry
Gene Ontology
regulation of G protein-coupled receptor signaling pathway

Displaying entries **1 - 10** of 13 in total

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InterPro
GoLoco motif
PDZ domain
PDZ superfamily
PH-like domain superfamily
PTB/PI domain
RGS domain superfamily
RGS domain
RGS, subdomain 1/3
RGS, subdomain 2
RGS12, RGS domain