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protein disulfide isomerase associated 6

Summary

Gene Symbol

Pdia6

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

71853

PubChem

71853

Alliance of Genome Resources

MGI:1919103

Annotation

Keyword

3D-structure
Cell membrane
Chaperone
Direct protein sequencing
Disulfide bond
Endoplasmic reticulum
Isomerase
Phosphoprotein
Proteomics identification
Redox-active center
Reference proteome
Repeat
Signal

Proteins

Displaying **all 2** entries
UniProt	Protein Name
Q922R8	Thioredoxin domain-containing protein 7
Q3TML0	Thioredoxin domain-containing protein 7

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 4** entries
GO Term	Evidence Code	PMID
platelet activation	ISS
response to endoplasmic reticulum stress	IBA
platelet aggregation	ISS
negative regulation of IRE1-mediated unfolded protein response	IMP	24508390

GO Hierarchy

biological process

cellular process [inference]

cell activation [inference]

platelet activation

cell adhesion [inference]

cell-cell adhesion [inference]

homotypic cell-cell adhesion [inference]

platelet aggregation

cellular response to stimulus [inference]

cellular response to stress [inference]

response to endoplasmic reticulum stress

multicellular organismal process [inference]

cell activation [inference]

platelet activation

response to stimulus [inference]

response to stress [inference]

cellular response to stress [inference]

response to endoplasmic reticulum stress

cellular response to stimulus [inference]

cellular response to stress [inference]

response to endoplasmic reticulum stress

biological regulation [inference]

regulation of biological process [inference]

regulation of signaling [inference]

regulation of signal transduction [inference]

negative regulation of signal transduction [inference]

negative regulation of endoplasmic reticulum unfolded protein response [inference]

negative regulation of IRE1-mediated unfolded protein response

regulation of endoplasmic reticulum unfolded protein response [inference]

negative regulation of endoplasmic reticulum unfolded protein response [inference]

negative regulation of IRE1-mediated unfolded protein response

regulation of IRE1-mediated unfolded protein response [inference]

negative regulation of IRE1-mediated unfolded protein response

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of endoplasmic reticulum unfolded protein response [inference]

negative regulation of IRE1-mediated unfolded protein response

negative regulation of biological process [inference]

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of endoplasmic reticulum unfolded protein response [inference]

negative regulation of IRE1-mediated unfolded protein response

negative regulation of cellular process [inference]

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of endoplasmic reticulum unfolded protein response [inference]

negative regulation of IRE1-mediated unfolded protein response

negative regulation of response to endoplasmic reticulum stress [inference]

negative regulation of endoplasmic reticulum unfolded protein response [inference]

negative regulation of IRE1-mediated unfolded protein response

negative regulation of response to stimulus [inference]

negative regulation of signal transduction [inference]

negative regulation of endoplasmic reticulum unfolded protein response [inference]

negative regulation of IRE1-mediated unfolded protein response

negative regulation of response to endoplasmic reticulum stress [inference]

negative regulation of endoplasmic reticulum unfolded protein response [inference]

negative regulation of IRE1-mediated unfolded protein response

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

negative regulation of signal transduction [inference]

negative regulation of endoplasmic reticulum unfolded protein response [inference]

negative regulation of IRE1-mediated unfolded protein response

regulation of endoplasmic reticulum unfolded protein response [inference]

negative regulation of endoplasmic reticulum unfolded protein response [inference]

negative regulation of IRE1-mediated unfolded protein response

regulation of IRE1-mediated unfolded protein response [inference]

negative regulation of IRE1-mediated unfolded protein response

negative regulation of response to stimulus [inference]

negative regulation of signal transduction [inference]

negative regulation of endoplasmic reticulum unfolded protein response [inference]

negative regulation of IRE1-mediated unfolded protein response

negative regulation of response to endoplasmic reticulum stress [inference]

negative regulation of endoplasmic reticulum unfolded protein response [inference]

negative regulation of IRE1-mediated unfolded protein response

regulation of response to stress [inference]

regulation of cellular response to stress [inference]

regulation of response to endoplasmic reticulum stress [inference]

regulation of endoplasmic reticulum unfolded protein response [inference]

negative regulation of endoplasmic reticulum unfolded protein response [inference]

negative regulation of IRE1-mediated unfolded protein response

regulation of IRE1-mediated unfolded protein response [inference]

negative regulation of IRE1-mediated unfolded protein response

negative regulation of response to endoplasmic reticulum stress [inference]

negative regulation of endoplasmic reticulum unfolded protein response [inference]

negative regulation of IRE1-mediated unfolded protein response

regulation of cellular process [inference]

regulation of cell communication [inference]

regulation of signal transduction [inference]

negative regulation of signal transduction [inference]

negative regulation of endoplasmic reticulum unfolded protein response [inference]

negative regulation of IRE1-mediated unfolded protein response

regulation of endoplasmic reticulum unfolded protein response [inference]

negative regulation of endoplasmic reticulum unfolded protein response [inference]

negative regulation of IRE1-mediated unfolded protein response

regulation of IRE1-mediated unfolded protein response [inference]

negative regulation of IRE1-mediated unfolded protein response

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of endoplasmic reticulum unfolded protein response [inference]

negative regulation of IRE1-mediated unfolded protein response

negative regulation of cellular process [inference]

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of endoplasmic reticulum unfolded protein response [inference]

negative regulation of IRE1-mediated unfolded protein response

negative regulation of response to endoplasmic reticulum stress [inference]

negative regulation of endoplasmic reticulum unfolded protein response [inference]

negative regulation of IRE1-mediated unfolded protein response

regulation of cellular response to stress [inference]

regulation of response to endoplasmic reticulum stress [inference]

regulation of endoplasmic reticulum unfolded protein response [inference]

negative regulation of endoplasmic reticulum unfolded protein response [inference]

negative regulation of IRE1-mediated unfolded protein response

regulation of IRE1-mediated unfolded protein response [inference]

negative regulation of IRE1-mediated unfolded protein response

negative regulation of response to endoplasmic reticulum stress [inference]

negative regulation of endoplasmic reticulum unfolded protein response [inference]

negative regulation of IRE1-mediated unfolded protein response

Displaying entries **1 - 5** of 11 in total

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GO Term	Evidence Code	PMID
extracellular space	ISO
endoplasmic reticulum	ISO
endoplasmic reticulum	IBA
endoplasmic reticulum lumen	ISO
endoplasmic reticulum lumen	IEA

GO Hierarchy

cellular component

protein-containing complex [inference]

endoplasmic reticulum protein-containing complex [inference]

endoplasmic reticulum chaperone complex

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

membrane-enclosed lumen [inference]

organelle lumen [inference]

intracellular organelle lumen [inference]

endoplasmic reticulum lumen

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

pigment granule [inference]

melanosome

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

smooth endoplasmic reticulum

endoplasmic reticulum-Golgi intermediate compartment

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

pigment granule [inference]

melanosome

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

smooth endoplasmic reticulum

endoplasmic reticulum-Golgi intermediate compartment

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

pigment granule [inference]

melanosome

Displaying **all 4** entries
GO Term	Evidence Code	PMID
protein disulfide isomerase activity	ISS
protein-disulfide reductase activity	ISO
protein-disulfide reductase activity	IMP	24508390
protein-disulfide reductase activity	IBA