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prolylcarboxypeptidase (angiotensinase C)

Summary

Gene Symbol

Prcp

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

72461

PubChem

72461

Alliance of Genome Resources

MGI:1919711

Annotation

Keyword

Alternative splicing
Carboxypeptidase
Disulfide bond
Glycoprotein
Lysosome
Reference proteome
Signal
Zymogen

Proteins

Displaying 1 entry
UniProt	Protein Name
Q7TMR0	Proline carboxypeptidase Prolylcarboxypeptidase

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 9 in total

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GO Term	Evidence Code	PMID
plasma kallikrein-kinin cascade	IMP	21297000
angiogenesis involved in wound healing	IBA IMP	23744584
proteolysis	IEA
regulation of blood vessel endothelial cell migration	IBA IMP ISO	23744584
regulation of reactive oxygen species metabolic process	IMP	21297000

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

proteolysis

protein maturation [inference]

protein activation cascade [inference]

kinin cascade [inference]

plasma kallikrein-kinin cascade

primary metabolic process [inference]

protein metabolic process [inference]

proteolysis

protein maturation [inference]

protein activation cascade [inference]

kinin cascade [inference]

plasma kallikrein-kinin cascade

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

protein metabolic process [inference]

proteolysis

protein maturation [inference]

protein activation cascade [inference]

kinin cascade [inference]

plasma kallikrein-kinin cascade

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

proteolysis

protein maturation [inference]

protein activation cascade [inference]

kinin cascade [inference]

plasma kallikrein-kinin cascade

multicellular organismal process [inference]

multicellular organismal-level homeostasis [inference]

energy homeostasis

developmental process [inference]

anatomical structure formation involved in morphogenesis [inference]

angiogenesis [inference]

angiogenesis involved in wound healing

homeostatic process [inference]

multicellular organismal-level homeostasis [inference]

energy homeostasis

chemical homeostasis [inference]

carbohydrate homeostasis [inference]

glucose homeostasis

response to stimulus [inference]

response to stress [inference]

defense response [inference]

inflammatory response [inference]

acute inflammatory response [inference]

kinin cascade [inference]

plasma kallikrein-kinin cascade

biological regulation [inference]

regulation of biological process [inference]

regulation of metabolic process [inference]

regulation of cellular metabolic process [inference]

regulation of reactive oxygen species metabolic process

regulation of signaling [inference]

regulation of signal transduction [inference]

regulation of thyroid hormone mediated signaling pathway

regulation of locomotion [inference]

regulation of cell motility [inference]

regulation of cell migration [inference]

regulation of epithelial cell migration [inference]

regulation of endothelial cell migration [inference]

regulation of blood vessel endothelial cell migration

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

regulation of thyroid hormone mediated signaling pathway

regulation of cellular process [inference]

regulation of cell communication [inference]

regulation of signal transduction [inference]

regulation of thyroid hormone mediated signaling pathway

regulation of cellular metabolic process [inference]

regulation of reactive oxygen species metabolic process

regulation of cell motility [inference]

regulation of cell migration [inference]

regulation of epithelial cell migration [inference]

regulation of endothelial cell migration [inference]

regulation of blood vessel endothelial cell migration

regulation of multicellular organismal process [inference]

regulation of epithelial cell migration [inference]

regulation of endothelial cell migration [inference]

regulation of blood vessel endothelial cell migration

regulation of biological quality [inference]

regulation of blood pressure [inference]

negative regulation of blood pressure [inference]

negative regulation of systemic arterial blood pressure

Displaying **all 3** entries
GO Term	Evidence Code	PMID
basal part of cell	IDA	21297000
intracellular membrane-bounded organelle	ISO
lysosome	IDA	29514215

GO Hierarchy

cellular component

cellular anatomical entity [inference]

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle

vacuole [inference]

lytic vacuole [inference]

lysosome

intracellular organelle [inference]

intracellular membrane-bounded organelle

vacuole [inference]

lytic vacuole [inference]

lysosome

basal part of cell

Displaying **all 2** entries
GO Term	Evidence Code	PMID
serine-type carboxypeptidase activity	IEA
dipeptidyl-peptidase activity	IBA

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

peptidase activity [inference]

serine-type peptidase activity [inference]

serine-type exopeptidase activity [inference]

serine-type carboxypeptidase activity

exopeptidase activity [inference]

carboxypeptidase activity [inference]

serine-type carboxypeptidase activity

dipeptidyl-peptidase activity

serine-type exopeptidase activity [inference]

serine-type carboxypeptidase activity

serine hydrolase activity [inference]

serine-type peptidase activity [inference]

serine-type exopeptidase activity [inference]

serine-type carboxypeptidase activity

catalytic activity, acting on a protein [inference]

peptidase activity [inference]

serine-type peptidase activity [inference]

serine-type exopeptidase activity [inference]

serine-type carboxypeptidase activity

exopeptidase activity [inference]

carboxypeptidase activity [inference]

serine-type carboxypeptidase activity

dipeptidyl-peptidase activity

serine-type exopeptidase activity [inference]

serine-type carboxypeptidase activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Rodentia

Group Name

lysosomal Pro-X carboxypeptidase

Functional Category

J: Translation, ribosomal structure and biogenesis
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 8** entries
Gene Ontology
angiogenesis involved in wound healing
carboxypeptidase activity
dipeptidyl-peptidase activity
hydrolase activity
negative regulation of systemic arterial blood pressure
proteolysis
regulation of blood vessel endothelial cell migration
serine-type exopeptidase activity

Displaying **all 3** entries
InterPro
Alpha/Beta hydrolase fold
Peptidase S28
Serine carboxypeptidase S28, SKS domain

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:3454	brain infarction	Alliance of Genome Resources

Ortholog

Displaying entries **41 - 50** of **101** in total

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Species	Gene ID	OrthoDB	Orthologous MAtrix
Astyanax mexicanus	103038921		ASTMX02258
Chlorocebus sabaeus	103248123		CHLSB00852
Nannospalax galili	103742987	1026970_0:002df1	NANGA00261
Serinus canaria	103827244		SERCA01391
Rhinopithecus roxellana	104662004		RHIRO38244
Fukomys damarensis	104866718	885580_0:001dd5
Macaca nemestrina	105468827		MACNE13154
Mandrillus leucophaeus	105551243		MANLE26431
Cercocebus atys	105578671		CERAT17308
Aotus nancymaae	105728964		AOTNA10614

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Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements