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tumor susceptibility 101

Summary

Gene Symbol

TSG101

Organism

Homo sapiens (human)

External Links

NCBI Gene

7251

PubChem

7251

Alliance of Genome Resources

HGNC:15971

Annotation

Keyword

3D-structure
Acetylation
Alternative splicing
Cell division
Coiled coil
Cytoskeleton
Endosome
Growth regulation
Host-virus interaction
Membrane
Nucleus
Phosphoprotein
Protein transport
Reference proteome
Ubl conjugation

Proteins

Displaying 1 entry
UniProt	Protein Name
Q99816	ESCRT-I complex subunit TSG101

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 30 in total

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GO Term	Evidence Code	PMID
negative regulation of transcription by RNA polymerase II	IEA
regulation of cell growth	IEA
extracellular transport	IMP	22315426
negative regulation of epidermal growth factor-activated receptor activity	IMP	16973552
negative regulation of cell population proliferation	IEA

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

proteolysis [inference]

proteolysis involved in protein catabolic process [inference]

modification-dependent protein catabolic process [inference]

ubiquitin-dependent protein catabolic process [inference]

ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway

protein modification process

catabolic process [inference]

cellular catabolic process [inference]

autophagy [inference]

macroautophagy

organic substance catabolic process [inference]

macromolecule catabolic process [inference]

modification-dependent macromolecule catabolic process [inference]

modification-dependent protein catabolic process [inference]

ubiquitin-dependent protein catabolic process [inference]

ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway

cellular metabolic process [inference]

cellular catabolic process [inference]

autophagy [inference]

macroautophagy

primary metabolic process [inference]

protein metabolic process [inference]

proteolysis [inference]

proteolysis involved in protein catabolic process [inference]

modification-dependent protein catabolic process [inference]

ubiquitin-dependent protein catabolic process [inference]

ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway

protein modification process

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

macromolecule catabolic process [inference]

modification-dependent macromolecule catabolic process [inference]

modification-dependent protein catabolic process [inference]

ubiquitin-dependent protein catabolic process [inference]

ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway

protein metabolic process [inference]

proteolysis [inference]

proteolysis involved in protein catabolic process [inference]

modification-dependent protein catabolic process [inference]

ubiquitin-dependent protein catabolic process [inference]

ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway

protein modification process

macromolecule modification [inference]

protein modification process

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

proteolysis [inference]

proteolysis involved in protein catabolic process [inference]

modification-dependent protein catabolic process [inference]

ubiquitin-dependent protein catabolic process [inference]

ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway

protein modification process

organic substance catabolic process [inference]

macromolecule catabolic process [inference]

modification-dependent macromolecule catabolic process [inference]

modification-dependent protein catabolic process [inference]

ubiquitin-dependent protein catabolic process [inference]

ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway

cellular process [inference]

vesicle-mediated transport [inference]

exocytosis [inference]

exosomal secretion

endosome to lysosome transport

endosomal transport [inference]

endosome transport via multivesicular body sorting pathway [inference]

late endosome to vacuole transport via multivesicular body sorting pathway [inference]

protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway

late endosome to vacuole transport [inference]

late endosome to vacuole transport via multivesicular body sorting pathway [inference]

protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway

multivesicular body sorting pathway [inference]

endosome transport via multivesicular body sorting pathway [inference]

late endosome to vacuole transport via multivesicular body sorting pathway [inference]

protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway

cellular metabolic process [inference]

cellular catabolic process [inference]

autophagy [inference]

macroautophagy

cellular developmental process [inference]

cell differentiation [inference]

epithelial cell differentiation [inference]

epidermal cell differentiation [inference]

keratinocyte differentiation

cell division

cellular localization [inference]

intracellular transport [inference]

intracellular protein transport [inference]

protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway

vacuolar transport [inference]

lysosomal transport [inference]

endosome to lysosome transport

late endosome to vacuole transport [inference]

late endosome to vacuole transport via multivesicular body sorting pathway [inference]

protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway

endosomal transport [inference]

endosome transport via multivesicular body sorting pathway [inference]

late endosome to vacuole transport via multivesicular body sorting pathway [inference]

protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to organelle [inference]

establishment of protein localization to organelle [inference]

establishment of protein localization to vacuole [inference]

protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway

protein localization to vacuole [inference]

establishment of protein localization to vacuole [inference]

protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway

establishment of protein localization [inference]

protein transport [inference]

intracellular protein transport [inference]

protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway

establishment of protein localization to organelle [inference]

establishment of protein localization to vacuole [inference]

protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway

process utilizing autophagic mechanism [inference]

autophagy [inference]

macroautophagy

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

vesicle organization [inference]

endosome organization [inference]

multivesicular body organization [inference]

multivesicular body assembly

organelle assembly [inference]

multivesicular body assembly

cellular component disassembly [inference]

protein-containing complex disassembly [inference]

autophagosome maturation

cellular component assembly [inference]

organelle assembly [inference]

multivesicular body assembly

protein-containing complex organization [inference]

protein-containing complex disassembly [inference]

autophagosome maturation

membrane organization [inference]

membrane fission

export from cell [inference]

secretion by cell [inference]

exocytosis [inference]

exosomal secretion

viral process [inference]

viral release from host cell

viral budding

viral budding via host ESCRT complex

developmental process [inference]

cellular developmental process [inference]

cell differentiation [inference]

epithelial cell differentiation [inference]

epidermal cell differentiation [inference]

keratinocyte differentiation

biological process involved in interspecies interaction between organisms [inference]

biological process involved in symbiotic interaction [inference]

biological process involved in interaction with host [inference]

movement in host [inference]

exit from host cell [inference]

viral release from host cell

localization [inference]

macromolecule localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to organelle [inference]

establishment of protein localization to organelle [inference]

establishment of protein localization to vacuole [inference]

protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway

protein localization to vacuole [inference]

establishment of protein localization to vacuole [inference]

protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway

establishment of protein localization [inference]

protein transport [inference]

intracellular protein transport [inference]

protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway

establishment of protein localization to organelle [inference]

establishment of protein localization to vacuole [inference]

protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway

establishment of localization [inference]

transport [inference]

extracellular transport

vesicle-mediated transport [inference]

exocytosis [inference]

exosomal secretion

endosome to lysosome transport

endosomal transport [inference]

endosome transport via multivesicular body sorting pathway [inference]

late endosome to vacuole transport via multivesicular body sorting pathway [inference]

protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway

late endosome to vacuole transport [inference]

late endosome to vacuole transport via multivesicular body sorting pathway [inference]

protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway

multivesicular body sorting pathway [inference]

endosome transport via multivesicular body sorting pathway [inference]

late endosome to vacuole transport via multivesicular body sorting pathway [inference]

protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway

secretion [inference]

secretion by cell [inference]

exocytosis [inference]

exosomal secretion

intracellular transport [inference]

intracellular protein transport [inference]

protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway

vacuolar transport [inference]

lysosomal transport [inference]

endosome to lysosome transport

late endosome to vacuole transport [inference]

late endosome to vacuole transport via multivesicular body sorting pathway [inference]

protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway

endosomal transport [inference]

endosome transport via multivesicular body sorting pathway [inference]

late endosome to vacuole transport via multivesicular body sorting pathway [inference]

protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway

organic substance transport [inference]

protein transport [inference]

intracellular protein transport [inference]

protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway

nitrogen compound transport [inference]

protein transport [inference]

intracellular protein transport [inference]

protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway

export from cell [inference]

secretion by cell [inference]

exocytosis [inference]

exosomal secretion

establishment of protein localization [inference]

protein transport [inference]

intracellular protein transport [inference]

protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway

establishment of protein localization to organelle [inference]

establishment of protein localization to vacuole [inference]

protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway

establishment of localization in cell [inference]

intracellular transport [inference]

intracellular protein transport [inference]

protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway

vacuolar transport [inference]

lysosomal transport [inference]

endosome to lysosome transport

late endosome to vacuole transport [inference]

late endosome to vacuole transport via multivesicular body sorting pathway [inference]

protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway

endosomal transport [inference]

endosome transport via multivesicular body sorting pathway [inference]

late endosome to vacuole transport via multivesicular body sorting pathway [inference]

protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway

establishment of vesicle localization [inference]

exosomal secretion

establishment of organelle localization [inference]

establishment of vesicle localization [inference]

exosomal secretion

organelle localization [inference]

vesicle localization [inference]

establishment of vesicle localization [inference]

exosomal secretion

establishment of organelle localization [inference]

establishment of vesicle localization [inference]

exosomal secretion

cellular localization [inference]

intracellular transport [inference]

intracellular protein transport [inference]

protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway

vacuolar transport [inference]

lysosomal transport [inference]

endosome to lysosome transport

late endosome to vacuole transport [inference]

late endosome to vacuole transport via multivesicular body sorting pathway [inference]

protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway

endosomal transport [inference]

endosome transport via multivesicular body sorting pathway [inference]

late endosome to vacuole transport via multivesicular body sorting pathway [inference]

protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to organelle [inference]

establishment of protein localization to organelle [inference]

establishment of protein localization to vacuole [inference]

protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway

protein localization to vacuole [inference]

establishment of protein localization to vacuole [inference]

protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway

establishment of protein localization [inference]

protein transport [inference]

intracellular protein transport [inference]

protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway

establishment of protein localization to organelle [inference]

establishment of protein localization to vacuole [inference]

protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway

biological regulation [inference]

regulation of biological process [inference]

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of protein metabolic process [inference]

negative regulation of protein modification process [inference]

negative regulation of protein phosphorylation [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein tyrosine kinase activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

negative regulation of peptidyl-tyrosine phosphorylation [inference]

negative regulation of protein tyrosine kinase activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of cellular metabolic process [inference]

negative regulation of phosphorus metabolic process [inference]

negative regulation of phosphate metabolic process [inference]

negative regulation of phosphorylation [inference]

negative regulation of protein phosphorylation [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein tyrosine kinase activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

negative regulation of peptidyl-tyrosine phosphorylation [inference]

negative regulation of protein tyrosine kinase activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

negative regulation of kinase activity [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein tyrosine kinase activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of nitrogen compound metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of protein metabolic process [inference]

negative regulation of protein modification process [inference]

negative regulation of protein phosphorylation [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein tyrosine kinase activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

negative regulation of peptidyl-tyrosine phosphorylation [inference]

negative regulation of protein tyrosine kinase activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

regulation of cellular metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

regulation of RNA metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of cellular metabolic process [inference]

negative regulation of phosphorus metabolic process [inference]

negative regulation of phosphate metabolic process [inference]

negative regulation of phosphorylation [inference]

negative regulation of protein phosphorylation [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein tyrosine kinase activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

negative regulation of peptidyl-tyrosine phosphorylation [inference]

negative regulation of protein tyrosine kinase activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

negative regulation of kinase activity [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein tyrosine kinase activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

regulation of phosphorus metabolic process [inference]

negative regulation of phosphorus metabolic process [inference]

negative regulation of phosphate metabolic process [inference]

negative regulation of phosphorylation [inference]

negative regulation of protein phosphorylation [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein tyrosine kinase activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

negative regulation of peptidyl-tyrosine phosphorylation [inference]

negative regulation of protein tyrosine kinase activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

negative regulation of kinase activity [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein tyrosine kinase activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

regulation of phosphate metabolic process [inference]

regulation of phosphorylation [inference]

regulation of protein phosphorylation [inference]

negative regulation of protein phosphorylation [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein tyrosine kinase activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

negative regulation of peptidyl-tyrosine phosphorylation [inference]

negative regulation of protein tyrosine kinase activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

regulation of protein kinase activity [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein tyrosine kinase activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

regulation of protein tyrosine kinase activity [inference]

regulation of epidermal growth factor-activated receptor activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

negative regulation of protein tyrosine kinase activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

regulation of protein serine/threonine kinase activity [inference]

regulation of MAP kinase activity

regulation of peptidyl-tyrosine phosphorylation [inference]

negative regulation of peptidyl-tyrosine phosphorylation [inference]

negative regulation of protein tyrosine kinase activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

regulation of protein tyrosine kinase activity [inference]

regulation of epidermal growth factor-activated receptor activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

negative regulation of protein tyrosine kinase activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

negative regulation of phosphorylation [inference]

negative regulation of protein phosphorylation [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein tyrosine kinase activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

negative regulation of peptidyl-tyrosine phosphorylation [inference]

negative regulation of protein tyrosine kinase activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

negative regulation of kinase activity [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein tyrosine kinase activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

regulation of kinase activity [inference]

negative regulation of kinase activity [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein tyrosine kinase activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

regulation of protein kinase activity [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein tyrosine kinase activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

regulation of protein tyrosine kinase activity [inference]

regulation of epidermal growth factor-activated receptor activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

negative regulation of protein tyrosine kinase activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

regulation of protein serine/threonine kinase activity [inference]

regulation of MAP kinase activity

negative regulation of phosphate metabolic process [inference]

negative regulation of phosphorylation [inference]

negative regulation of protein phosphorylation [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein tyrosine kinase activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

negative regulation of peptidyl-tyrosine phosphorylation [inference]

negative regulation of protein tyrosine kinase activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

negative regulation of kinase activity [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein tyrosine kinase activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

regulation of nitrogen compound metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

regulation of RNA metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of nitrogen compound metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of protein metabolic process [inference]

negative regulation of protein modification process [inference]

negative regulation of protein phosphorylation [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein tyrosine kinase activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

negative regulation of peptidyl-tyrosine phosphorylation [inference]

negative regulation of protein tyrosine kinase activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

regulation of protein metabolic process [inference]

regulation of protein modification process [inference]

regulation of protein phosphorylation [inference]

negative regulation of protein phosphorylation [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein tyrosine kinase activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

negative regulation of peptidyl-tyrosine phosphorylation [inference]

negative regulation of protein tyrosine kinase activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

regulation of protein kinase activity [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein tyrosine kinase activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

regulation of protein tyrosine kinase activity [inference]

regulation of epidermal growth factor-activated receptor activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

negative regulation of protein tyrosine kinase activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

regulation of protein serine/threonine kinase activity [inference]

regulation of MAP kinase activity

regulation of peptidyl-tyrosine phosphorylation [inference]

negative regulation of peptidyl-tyrosine phosphorylation [inference]

negative regulation of protein tyrosine kinase activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

regulation of protein tyrosine kinase activity [inference]

regulation of epidermal growth factor-activated receptor activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

negative regulation of protein tyrosine kinase activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

negative regulation of protein modification process [inference]

negative regulation of protein phosphorylation [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein tyrosine kinase activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

negative regulation of peptidyl-tyrosine phosphorylation [inference]

negative regulation of protein tyrosine kinase activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

negative regulation of protein metabolic process [inference]

negative regulation of protein modification process [inference]

negative regulation of protein phosphorylation [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein tyrosine kinase activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

negative regulation of peptidyl-tyrosine phosphorylation [inference]

negative regulation of protein tyrosine kinase activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of protein metabolic process [inference]

negative regulation of protein modification process [inference]

negative regulation of protein phosphorylation [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein tyrosine kinase activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

negative regulation of peptidyl-tyrosine phosphorylation [inference]

negative regulation of protein tyrosine kinase activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

regulation of protein metabolic process [inference]

regulation of protein modification process [inference]

regulation of protein phosphorylation [inference]

negative regulation of protein phosphorylation [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein tyrosine kinase activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

negative regulation of peptidyl-tyrosine phosphorylation [inference]

negative regulation of protein tyrosine kinase activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

regulation of protein kinase activity [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein tyrosine kinase activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

regulation of protein tyrosine kinase activity [inference]

regulation of epidermal growth factor-activated receptor activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

negative regulation of protein tyrosine kinase activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

regulation of protein serine/threonine kinase activity [inference]

regulation of MAP kinase activity

regulation of peptidyl-tyrosine phosphorylation [inference]

negative regulation of peptidyl-tyrosine phosphorylation [inference]

negative regulation of protein tyrosine kinase activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

regulation of protein tyrosine kinase activity [inference]

regulation of epidermal growth factor-activated receptor activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

negative regulation of protein tyrosine kinase activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

negative regulation of protein modification process [inference]

negative regulation of protein phosphorylation [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein tyrosine kinase activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

negative regulation of peptidyl-tyrosine phosphorylation [inference]

negative regulation of protein tyrosine kinase activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

negative regulation of protein metabolic process [inference]

negative regulation of protein modification process [inference]

negative regulation of protein phosphorylation [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein tyrosine kinase activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

negative regulation of peptidyl-tyrosine phosphorylation [inference]

negative regulation of protein tyrosine kinase activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

regulation of RNA metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

regulation of primary metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

regulation of RNA metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

regulation of protein metabolic process [inference]

regulation of protein modification process [inference]

regulation of protein phosphorylation [inference]

negative regulation of protein phosphorylation [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein tyrosine kinase activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

negative regulation of peptidyl-tyrosine phosphorylation [inference]

negative regulation of protein tyrosine kinase activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

regulation of protein kinase activity [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein tyrosine kinase activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

regulation of protein tyrosine kinase activity [inference]

regulation of epidermal growth factor-activated receptor activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

negative regulation of protein tyrosine kinase activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

regulation of protein serine/threonine kinase activity [inference]

regulation of MAP kinase activity

regulation of peptidyl-tyrosine phosphorylation [inference]

negative regulation of peptidyl-tyrosine phosphorylation [inference]

negative regulation of protein tyrosine kinase activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

regulation of protein tyrosine kinase activity [inference]

regulation of epidermal growth factor-activated receptor activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

negative regulation of protein tyrosine kinase activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

negative regulation of protein modification process [inference]

negative regulation of protein phosphorylation [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein tyrosine kinase activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

negative regulation of peptidyl-tyrosine phosphorylation [inference]

negative regulation of protein tyrosine kinase activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

negative regulation of protein metabolic process [inference]

negative regulation of protein modification process [inference]

negative regulation of protein phosphorylation [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein tyrosine kinase activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

negative regulation of peptidyl-tyrosine phosphorylation [inference]

negative regulation of protein tyrosine kinase activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

regulation of signaling [inference]

regulation of signal transduction [inference]

negative regulation of signal transduction [inference]

negative regulation of ERBB signaling pathway [inference]

negative regulation of epidermal growth factor receptor signaling pathway

negative regulation of epidermal growth factor-activated receptor activity

regulation of signaling receptor activity [inference]

regulation of epidermal growth factor-activated receptor activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

negative regulation of signaling receptor activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

regulation of ERBB signaling pathway [inference]

regulation of epidermal growth factor receptor signaling pathway [inference]

negative regulation of epidermal growth factor receptor signaling pathway

negative regulation of epidermal growth factor-activated receptor activity

negative regulation of ERBB signaling pathway [inference]

negative regulation of epidermal growth factor receptor signaling pathway

negative regulation of epidermal growth factor-activated receptor activity

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of ERBB signaling pathway [inference]

negative regulation of epidermal growth factor receptor signaling pathway

negative regulation of epidermal growth factor-activated receptor activity

regulation of localization [inference]

regulation of transport [inference]

regulation of secretion [inference]

positive regulation of secretion [inference]

positive regulation of secretion by cell [inference]

positive regulation of exocytosis [inference]

positive regulation of exosomal secretion

regulation of secretion by cell [inference]

regulation of exocytosis [inference]

positive regulation of exocytosis [inference]

positive regulation of exosomal secretion

regulation of exosomal secretion [inference]

positive regulation of exosomal secretion

positive regulation of secretion by cell [inference]

positive regulation of exocytosis [inference]

positive regulation of exosomal secretion

positive regulation of transport [inference]

positive regulation of endocytosis [inference]

positive regulation of ubiquitin-dependent endocytosis

positive regulation of secretion [inference]

positive regulation of secretion by cell [inference]

positive regulation of exocytosis [inference]

positive regulation of exosomal secretion

positive regulation of protein transport [inference]

positive regulation of ubiquitin-dependent endocytosis

regulation of protein transport [inference]

positive regulation of protein transport [inference]

positive regulation of ubiquitin-dependent endocytosis

regulation of ubiquitin-dependent endocytosis [inference]

positive regulation of ubiquitin-dependent endocytosis

regulation of vesicle-mediated transport [inference]

regulation of exocytosis [inference]

positive regulation of exocytosis [inference]

positive regulation of exosomal secretion

regulation of exosomal secretion [inference]

positive regulation of exosomal secretion

regulation of endocytosis [inference]

positive regulation of endocytosis [inference]

positive regulation of ubiquitin-dependent endocytosis

regulation of ubiquitin-dependent endocytosis [inference]

positive regulation of ubiquitin-dependent endocytosis

regulation of cellular localization [inference]

regulation of protein localization [inference]

regulation of establishment of protein localization [inference]

regulation of protein transport [inference]

positive regulation of protein transport [inference]

positive regulation of ubiquitin-dependent endocytosis

regulation of ubiquitin-dependent endocytosis [inference]

positive regulation of ubiquitin-dependent endocytosis

positive regulation of establishment of protein localization [inference]

positive regulation of protein transport [inference]

positive regulation of ubiquitin-dependent endocytosis

positive regulation of protein localization [inference]

positive regulation of establishment of protein localization [inference]

positive regulation of protein transport [inference]

positive regulation of ubiquitin-dependent endocytosis

regulation of growth [inference]

regulation of cell growth

positive regulation of biological process [inference]

positive regulation of cellular process [inference]

positive regulation of cellular component biogenesis [inference]

positive regulation of exosomal secretion

positive regulation of cellular component organization [inference]

positive regulation of endocytosis [inference]

positive regulation of ubiquitin-dependent endocytosis

positive regulation of secretion by cell [inference]

positive regulation of exocytosis [inference]

positive regulation of exosomal secretion

positive regulation of protein localization [inference]

positive regulation of establishment of protein localization [inference]

positive regulation of protein transport [inference]

positive regulation of ubiquitin-dependent endocytosis

positive regulation of viral process [inference]

positive regulation of viral life cycle [inference]

positive regulation of viral budding via host ESCRT complex

positive regulation of transport [inference]

positive regulation of endocytosis [inference]

positive regulation of ubiquitin-dependent endocytosis

positive regulation of secretion [inference]

positive regulation of secretion by cell [inference]

positive regulation of exocytosis [inference]

positive regulation of exosomal secretion

positive regulation of protein transport [inference]

positive regulation of ubiquitin-dependent endocytosis

negative regulation of biological process [inference]

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of protein metabolic process [inference]

negative regulation of protein modification process [inference]

negative regulation of protein phosphorylation [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein tyrosine kinase activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

negative regulation of peptidyl-tyrosine phosphorylation [inference]

negative regulation of protein tyrosine kinase activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of cellular metabolic process [inference]

negative regulation of phosphorus metabolic process [inference]

negative regulation of phosphate metabolic process [inference]

negative regulation of phosphorylation [inference]

negative regulation of protein phosphorylation [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein tyrosine kinase activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

negative regulation of peptidyl-tyrosine phosphorylation [inference]

negative regulation of protein tyrosine kinase activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

negative regulation of kinase activity [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein tyrosine kinase activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of nitrogen compound metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of protein metabolic process [inference]

negative regulation of protein modification process [inference]

negative regulation of protein phosphorylation [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein tyrosine kinase activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

negative regulation of peptidyl-tyrosine phosphorylation [inference]

negative regulation of protein tyrosine kinase activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of ERBB signaling pathway [inference]

negative regulation of epidermal growth factor receptor signaling pathway

negative regulation of epidermal growth factor-activated receptor activity

negative regulation of cellular process [inference]

negative regulation of cell population proliferation

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of ERBB signaling pathway [inference]

negative regulation of epidermal growth factor receptor signaling pathway

negative regulation of epidermal growth factor-activated receptor activity

negative regulation of cellular metabolic process [inference]

negative regulation of phosphorus metabolic process [inference]

negative regulation of phosphate metabolic process [inference]

negative regulation of phosphorylation [inference]

negative regulation of protein phosphorylation [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein tyrosine kinase activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

negative regulation of peptidyl-tyrosine phosphorylation [inference]

negative regulation of protein tyrosine kinase activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

negative regulation of kinase activity [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein tyrosine kinase activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of response to stimulus [inference]

negative regulation of signal transduction [inference]

negative regulation of ERBB signaling pathway [inference]

negative regulation of epidermal growth factor receptor signaling pathway

negative regulation of epidermal growth factor-activated receptor activity

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

negative regulation of signal transduction [inference]

negative regulation of ERBB signaling pathway [inference]

negative regulation of epidermal growth factor receptor signaling pathway

negative regulation of epidermal growth factor-activated receptor activity

regulation of signaling receptor activity [inference]

regulation of epidermal growth factor-activated receptor activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

negative regulation of signaling receptor activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

regulation of ERBB signaling pathway [inference]

regulation of epidermal growth factor receptor signaling pathway [inference]

negative regulation of epidermal growth factor receptor signaling pathway

negative regulation of epidermal growth factor-activated receptor activity

negative regulation of ERBB signaling pathway [inference]

negative regulation of epidermal growth factor receptor signaling pathway

negative regulation of epidermal growth factor-activated receptor activity

negative regulation of response to stimulus [inference]

negative regulation of signal transduction [inference]

negative regulation of ERBB signaling pathway [inference]

negative regulation of epidermal growth factor receptor signaling pathway

negative regulation of epidermal growth factor-activated receptor activity

regulation of viral process [inference]

positive regulation of viral process [inference]

positive regulation of viral life cycle [inference]

positive regulation of viral budding via host ESCRT complex

regulation of viral budding via host ESCRT complex [inference]

positive regulation of viral budding via host ESCRT complex

regulation of viral life cycle [inference]

positive regulation of viral life cycle [inference]

positive regulation of viral budding via host ESCRT complex

regulation of cellular process [inference]

regulation of cell communication [inference]

regulation of signal transduction [inference]

negative regulation of signal transduction [inference]

negative regulation of ERBB signaling pathway [inference]

negative regulation of epidermal growth factor receptor signaling pathway

negative regulation of epidermal growth factor-activated receptor activity

regulation of signaling receptor activity [inference]

regulation of epidermal growth factor-activated receptor activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

negative regulation of signaling receptor activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

regulation of ERBB signaling pathway [inference]

regulation of epidermal growth factor receptor signaling pathway [inference]

negative regulation of epidermal growth factor receptor signaling pathway

negative regulation of epidermal growth factor-activated receptor activity

negative regulation of ERBB signaling pathway [inference]

negative regulation of epidermal growth factor receptor signaling pathway

negative regulation of epidermal growth factor-activated receptor activity

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of ERBB signaling pathway [inference]

negative regulation of epidermal growth factor receptor signaling pathway

negative regulation of epidermal growth factor-activated receptor activity

regulation of cellular metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

regulation of RNA metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of cellular metabolic process [inference]

negative regulation of phosphorus metabolic process [inference]

negative regulation of phosphate metabolic process [inference]

negative regulation of phosphorylation [inference]

negative regulation of protein phosphorylation [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein tyrosine kinase activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

negative regulation of peptidyl-tyrosine phosphorylation [inference]

negative regulation of protein tyrosine kinase activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

negative regulation of kinase activity [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein tyrosine kinase activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

regulation of phosphorus metabolic process [inference]

negative regulation of phosphorus metabolic process [inference]

negative regulation of phosphate metabolic process [inference]

negative regulation of phosphorylation [inference]

negative regulation of protein phosphorylation [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein tyrosine kinase activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

negative regulation of peptidyl-tyrosine phosphorylation [inference]

negative regulation of protein tyrosine kinase activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

negative regulation of kinase activity [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein tyrosine kinase activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

regulation of phosphate metabolic process [inference]

regulation of phosphorylation [inference]

regulation of protein phosphorylation [inference]

negative regulation of protein phosphorylation [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein tyrosine kinase activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

negative regulation of peptidyl-tyrosine phosphorylation [inference]

negative regulation of protein tyrosine kinase activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

regulation of protein kinase activity [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein tyrosine kinase activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

regulation of protein tyrosine kinase activity [inference]

regulation of epidermal growth factor-activated receptor activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

negative regulation of protein tyrosine kinase activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

regulation of protein serine/threonine kinase activity [inference]

regulation of MAP kinase activity

regulation of peptidyl-tyrosine phosphorylation [inference]

negative regulation of peptidyl-tyrosine phosphorylation [inference]

negative regulation of protein tyrosine kinase activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

regulation of protein tyrosine kinase activity [inference]

regulation of epidermal growth factor-activated receptor activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

negative regulation of protein tyrosine kinase activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

negative regulation of phosphorylation [inference]

negative regulation of protein phosphorylation [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein tyrosine kinase activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

negative regulation of peptidyl-tyrosine phosphorylation [inference]

negative regulation of protein tyrosine kinase activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

negative regulation of kinase activity [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein tyrosine kinase activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

regulation of kinase activity [inference]

negative regulation of kinase activity [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein tyrosine kinase activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

regulation of protein kinase activity [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein tyrosine kinase activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

regulation of protein tyrosine kinase activity [inference]

regulation of epidermal growth factor-activated receptor activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

negative regulation of protein tyrosine kinase activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

regulation of protein serine/threonine kinase activity [inference]

regulation of MAP kinase activity

negative regulation of phosphate metabolic process [inference]

negative regulation of phosphorylation [inference]

negative regulation of protein phosphorylation [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein tyrosine kinase activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

negative regulation of peptidyl-tyrosine phosphorylation [inference]

negative regulation of protein tyrosine kinase activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

negative regulation of kinase activity [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein tyrosine kinase activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

regulation of cell population proliferation [inference]

negative regulation of cell population proliferation

regulation of cellular component biogenesis [inference]

positive regulation of cellular component biogenesis [inference]

positive regulation of exosomal secretion

regulation of organelle assembly [inference]

regulation of extracellular exosome assembly

positive regulation of cellular process [inference]

positive regulation of cellular component biogenesis [inference]

positive regulation of exosomal secretion

positive regulation of cellular component organization [inference]

positive regulation of endocytosis [inference]

positive regulation of ubiquitin-dependent endocytosis

positive regulation of secretion by cell [inference]

positive regulation of exocytosis [inference]

positive regulation of exosomal secretion

positive regulation of protein localization [inference]

positive regulation of establishment of protein localization [inference]

positive regulation of protein transport [inference]

positive regulation of ubiquitin-dependent endocytosis

negative regulation of cellular process [inference]

negative regulation of cell population proliferation

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of ERBB signaling pathway [inference]

negative regulation of epidermal growth factor receptor signaling pathway

negative regulation of epidermal growth factor-activated receptor activity

negative regulation of cellular metabolic process [inference]

negative regulation of phosphorus metabolic process [inference]

negative regulation of phosphate metabolic process [inference]

negative regulation of phosphorylation [inference]

negative regulation of protein phosphorylation [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein tyrosine kinase activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

negative regulation of peptidyl-tyrosine phosphorylation [inference]

negative regulation of protein tyrosine kinase activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

negative regulation of kinase activity [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein tyrosine kinase activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

regulation of cellular component organization [inference]

regulation of cell growth

regulation of endocytosis [inference]

positive regulation of endocytosis [inference]

positive regulation of ubiquitin-dependent endocytosis

regulation of ubiquitin-dependent endocytosis [inference]

positive regulation of ubiquitin-dependent endocytosis

regulation of organelle organization [inference]

regulation of organelle assembly [inference]

regulation of extracellular exosome assembly

positive regulation of cellular component organization [inference]

positive regulation of endocytosis [inference]

positive regulation of ubiquitin-dependent endocytosis

regulation of cell cycle

regulation of cellular localization [inference]

regulation of protein localization [inference]

regulation of establishment of protein localization [inference]

regulation of protein transport [inference]

positive regulation of protein transport [inference]

positive regulation of ubiquitin-dependent endocytosis

regulation of ubiquitin-dependent endocytosis [inference]

positive regulation of ubiquitin-dependent endocytosis

positive regulation of establishment of protein localization [inference]

positive regulation of protein transport [inference]

positive regulation of ubiquitin-dependent endocytosis

positive regulation of protein localization [inference]

positive regulation of establishment of protein localization [inference]

positive regulation of protein transport [inference]

positive regulation of ubiquitin-dependent endocytosis

regulation of vesicle-mediated transport [inference]

regulation of exocytosis [inference]

positive regulation of exocytosis [inference]

positive regulation of exosomal secretion

regulation of exosomal secretion [inference]

positive regulation of exosomal secretion

regulation of endocytosis [inference]

positive regulation of endocytosis [inference]

positive regulation of ubiquitin-dependent endocytosis

regulation of ubiquitin-dependent endocytosis [inference]

positive regulation of ubiquitin-dependent endocytosis

regulation of secretion by cell [inference]

regulation of exocytosis [inference]

positive regulation of exocytosis [inference]

positive regulation of exosomal secretion

regulation of exosomal secretion [inference]

positive regulation of exosomal secretion

positive regulation of secretion by cell [inference]

positive regulation of exocytosis [inference]

positive regulation of exosomal secretion

regulation of molecular function [inference]

regulation of signaling receptor activity [inference]

regulation of epidermal growth factor-activated receptor activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

negative regulation of signaling receptor activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

negative regulation of molecular function [inference]

negative regulation of catalytic activity [inference]

negative regulation of transferase activity [inference]

negative regulation of kinase activity [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein tyrosine kinase activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

negative regulation of signaling receptor activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

regulation of catalytic activity [inference]

negative regulation of catalytic activity [inference]

negative regulation of transferase activity [inference]

negative regulation of kinase activity [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein tyrosine kinase activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

regulation of transferase activity [inference]

regulation of kinase activity [inference]

negative regulation of kinase activity [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein tyrosine kinase activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

regulation of protein kinase activity [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein tyrosine kinase activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

regulation of protein tyrosine kinase activity [inference]

regulation of epidermal growth factor-activated receptor activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

negative regulation of protein tyrosine kinase activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

regulation of protein serine/threonine kinase activity [inference]

regulation of MAP kinase activity

negative regulation of transferase activity [inference]

negative regulation of kinase activity [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein tyrosine kinase activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

Displaying entries **1 - 5** of 22 in total

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GO Term	Evidence Code	PMID
ESCRT I complex	ISS
ESCRT I complex	TAS	20588296 21118109
ESCRT I complex	IDA	18005716 20654576 21757351 22232651
ESCRT I complex	IBA
ESCRT I complex	IPI	18005716 21757351 32424346

GO Hierarchy

cellular component

protein-containing complex [inference]

ESCRT complex [inference]

ESCRT I complex

membrane protein complex [inference]

ESCRT I complex

cellular anatomical entity [inference]

cytoplasm

microtubule organizing center [inference]

centrosome

cytosol

membrane [inference]

plasma membrane

organelle membrane [inference]

vesicle membrane [inference]

cytoplasmic vesicle membrane [inference]

endosome membrane

bounding membrane of organelle [inference]

endosome membrane

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome

early endosome

late endosome

multivesicular body

extracellular vesicle [inference]

extracellular exosome

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome

early endosome

late endosome

multivesicular body

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

non-membrane-bounded organelle [inference]

intracellular non-membrane-bounded organelle [inference]

nucleolus

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome

early endosome

late endosome

multivesicular body

intracellular non-membrane-bounded organelle [inference]

nucleolus

extracellular organelle [inference]

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

Flemming body

Displaying entries **1 - 5** of 11 in total

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GO Term	Evidence Code	PMID
DNA binding	TAS	10888872
transcription corepressor activity	IEA
protein binding	IPI	12802020 12900395 14505570 14519844 15033475 15218037 15611048 16118794 16189514 16973552 17174262 17350572 17853893 18005716 18077552 18641129 19060904 19549727 20176808 21070952 22315426 25416956 26871637 27107012 28514442 31515488 32296183 33961781 35044719 35271311 37100772 37219487
ubiquitin protein ligase binding	IPI	17229889
protein homodimerization activity	IPI	14519844

GO Hierarchy

molecular function

binding [inference]

protein binding

enzyme binding [inference]

ubiquitin-like protein ligase binding [inference]

ubiquitin protein ligase binding

ubiquitin-like protein binding [inference]

ubiquitin binding

identical protein binding [inference]

protein homodimerization activity

protein dimerization activity [inference]

protein homodimerization activity

calcium-dependent protein binding

organic cyclic compound binding [inference]

nucleic acid binding [inference]

DNA binding

transcription regulator activity [inference]

transcription coregulator activity [inference]

transcription corepressor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

tumor susceptibility

Functional Category

E: Amino acid transport and metabolism
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 2** entries
Gene Ontology
endosome to lysosome transport
ubiquitin binding

Displaying **all 4** entries
InterPro
ESCRT assembly domain
Steadiness box (SB) domain
Ubiquitin E2 variant, N-terminal
Ubiquitin-conjugating enzyme/RWD-like

Disease

Disease Ontology

Displaying **all 5** entries
DO ID	Disease Name	Source
DOID:10283	prostate cancer	Alliance of Genome Resources
DOID:1612	breast cancer	Alliance of Genome Resources
DOID:2870	endometrial adenocarcinoma	Alliance of Genome Resources
DOID:2893	cervix carcinoma	Alliance of Genome Resources
DOID:3459	breast carcinoma	Alliance of Genome Resources

Ortholog

Displaying entries **1 - 10** of 78 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Xenopus laevis	7251	Xenbase:XB-GENE-6255929
Mus musculus	22088		MOUSE56041
Rattus norvegicus	292925		RATNO18099
Danio rerio	415179		DANRE26885
Pan troglodytes	451065		PANTR02459
Canis lupus familiaris	485406		CANLF08594
Bos taurus	507659		BOVIN22942
Macaca mulatta	693787		MACMU11659
Bos taurus	786363		BOVIN22942
Monodelphis domestica	100019704		MONDO26837

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

Search Tools

Guidelines

Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements