thyroid stimulating hormone receptor

Summary
Gene Symbol
  • TSHR
Organism
Homo sapiens (human)
NCBI Gene
7253
PubChem
7253
Alliance of Genome Resources
JoGo
TSHR
TogoVar
TSHR
Annotation
Keyword
  • 3D-structure
  • Alternative splicing
  • Cell membrane
  • Congenital hypothyroidism
  • Direct protein sequencing
  • Disease variant
  • Disulfide bond
  • G-protein coupled receptor
  • Glycoprotein
  • Leucine-rich repeat
  • Proteomics identification
  • Reference proteome
  • Repeat
  • Signal
  • Sulfation
  • Transmembrane helix
Proteins
Displaying 1 entry
UniProt Protein Name
P16473
  • Thyroid-stimulating hormone receptor
Gene Ontology (GO)
GO Hierarchy
OrthoDB (Group)
Group level
Eukaryota
Group Name
lutropin-choriogonadotropic hormone receptor
Functional Category
  • K: Transcription
  • O: Posttranslational modification, protein turnover, chaperones
  • T: Signal transduction mechanisms
Disease
Disease Ontology
Displaying all 6 entries
DO ID Disease Name Source
DOID:0050700 cardiomyopathy
DOID:0081101 nonautoimmune hyperthyroidism
DOID:0081102 familial gestational hyperthyroidism
DOID:0081120 Graves ophthalmopathy
DOID:12361 Graves' disease
DOID:988 mitral valve prolapse

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: December 8, 2025