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tudor and KH domain containing protein

Summary

Gene Symbol

Tdrkh

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

72634

PubChem

72634

Alliance of Genome Resources

MGI:1919884

Annotation

Keyword

3D-structure
Cytoplasm
Isopeptide bond
Mitochondrion
Phosphoprotein
RNA-binding
RNA-mediated gene silencing
Reference proteome
Repeat
Spermatogenesis
Ubl conjugation

Proteins

Displaying 1 entry
UniProt	Protein Name
Q80VL1	Tudor domain-containing protein 2

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entry **6 - 6** of 6 in total

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GO Term	Evidence Code	PMID
cell differentiation	IEA

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

ncRNA processing [inference]

regulatory ncRNA processing [inference]

piRNA processing

ncRNA metabolic process [inference]

ncRNA processing [inference]

regulatory ncRNA processing [inference]

piRNA processing

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

ncRNA processing [inference]

regulatory ncRNA processing [inference]

piRNA processing

ncRNA metabolic process [inference]

ncRNA processing [inference]

regulatory ncRNA processing [inference]

piRNA processing

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

ncRNA processing [inference]

regulatory ncRNA processing [inference]

piRNA processing

ncRNA metabolic process [inference]

ncRNA processing [inference]

regulatory ncRNA processing [inference]

piRNA processing

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

ncRNA processing [inference]

regulatory ncRNA processing [inference]

piRNA processing

ncRNA metabolic process [inference]

ncRNA processing [inference]

regulatory ncRNA processing [inference]

piRNA processing

primary metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

ncRNA processing [inference]

regulatory ncRNA processing [inference]

piRNA processing

ncRNA metabolic process [inference]

ncRNA processing [inference]

regulatory ncRNA processing [inference]

piRNA processing

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

ncRNA processing [inference]

regulatory ncRNA processing [inference]

piRNA processing

ncRNA metabolic process [inference]

ncRNA processing [inference]

regulatory ncRNA processing [inference]

piRNA processing

organic cyclic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

ncRNA processing [inference]

regulatory ncRNA processing [inference]

piRNA processing

ncRNA metabolic process [inference]

ncRNA processing [inference]

regulatory ncRNA processing [inference]

piRNA processing

cellular process [inference]

cell cycle process [inference]

meiotic cell cycle process [inference]

meiotic nuclear division [inference]

male meiotic nuclear division

cellular process involved in reproduction in multicellular organism [inference]

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

ncRNA processing [inference]

regulatory ncRNA processing [inference]

piRNA processing

ncRNA metabolic process [inference]

ncRNA processing [inference]

regulatory ncRNA processing [inference]

piRNA processing

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

ncRNA processing [inference]

regulatory ncRNA processing [inference]

piRNA processing

ncRNA metabolic process [inference]

ncRNA processing [inference]

regulatory ncRNA processing [inference]

piRNA processing

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

ncRNA processing [inference]

regulatory ncRNA processing [inference]

piRNA processing

ncRNA metabolic process [inference]

ncRNA processing [inference]

regulatory ncRNA processing [inference]

piRNA processing

cellular developmental process [inference]

cell differentiation

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

P granule organization

organelle fission [inference]

nuclear division [inference]

meiotic nuclear division [inference]

male meiotic nuclear division

reproductive process [inference]

developmental process involved in reproduction [inference]

spermatogenesis

fertilization

cellular process involved in reproduction in multicellular organism [inference]

multicellular organismal reproductive process [inference]

gamete generation [inference]

male gamete generation [inference]

spermatogenesis

meiotic cell cycle process [inference]

meiotic nuclear division [inference]

male meiotic nuclear division

developmental process [inference]

developmental process involved in reproduction [inference]

spermatogenesis

cellular developmental process [inference]

cell differentiation

Displaying entry **6 - 6** of 6 in total

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GO Term	Evidence Code	PMID
cytoplasm	IDA	19918066

GO Hierarchy

cellular component

cellular anatomical entity [inference]

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

mitochondrion

non-membrane-bounded organelle [inference]

intracellular non-membrane-bounded organelle [inference]

ribonucleoprotein granule [inference]

cytoplasmic ribonucleoprotein granule [inference]

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

mitochondrion

intracellular non-membrane-bounded organelle [inference]

ribonucleoprotein granule [inference]

cytoplasmic ribonucleoprotein granule [inference]

supramolecular complex [inference]

ribonucleoprotein granule [inference]

cytoplasmic ribonucleoprotein granule [inference]

Displaying **all 2** entries
GO Term	Evidence Code	PMID
protein binding	IPI	19918066 23714778
RNA binding	IEA

GO Hierarchy

molecular function

binding [inference]

protein binding

organic cyclic compound binding [inference]

nucleic acid binding [inference]

RNA binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Rodentia

Group Name

tudor and KH domain-containing protein

Functional Category

K: Transcription
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying 1 entry
Gene Ontology
spermatogenesis

Displaying **all 8** entries
InterPro
K Homology domain, type 1 superfamily
K Homology domain, type 1
K Homology domain
SNase-like, OB-fold superfamily
Tudor and KH domain-containing protein, first type I K homology domain
Tudor and KH domain-containing protein, second type I K homology domain
Tudor domain-containing protein 2-like, tudor domain
Tudor domain

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:14227	azoospermia	Alliance of Genome Resources

Ortholog

Displaying entries **11 - 20** of **113** in total

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Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Callithrix jacchus	100391663			CALJA16395
Pongo abelii	100442598			PONAB16715
Ailuropoda melanoleuca	100471191			AILME12644
Nomascus leucogenys	100597503			NOMLE05996
Sus scrofa	100622748			PIGXX24114
Loxodonta africana	100665505			LOXAF15157
Oreochromis niloticus	100697575			ORENI72565
Cavia porcellus	100714350	10141_0:0049df		CAVPO01488
Cricetulus griseus	100767189	10029_0:004b94
Cricetulus griseus	100768467	10029_0:000719		CRIGR23708

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: December 9, 2024