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TTK protein kinase

Summary

Gene Symbol

Organism

Homo sapiens (human)

External Links

NCBI Gene

7272

PubChem

7272

Alliance of Genome Resources

HGNC:12401

Annotation

Keyword

3D-structure
ATP-binding
Acetylation
Alternative splicing
Phosphoprotein
Reference proteome
Serine/threonine-protein kinase
Tyrosine-protein kinase

Proteins

Displaying 1 entry
UniProt	Protein Name
P33981	Phosphotyrosine picked threonine-protein kinase

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 12 in total

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GO Term	Evidence Code	PMID
spindle organization	TAS	10366450
mitotic spindle organization	TAS	7737118
chromosome segregation	IBA
mitotic spindle assembly checkpoint signaling	IDA	18243099
mitotic spindle assembly checkpoint signaling	IBA

GO Hierarchy

biological process

cellular process [inference]

microtubule-based process [inference]

microtubule cytoskeleton organization [inference]

spindle organization

mitotic spindle organization

microtubule cytoskeleton organization involved in mitosis [inference]

mitotic spindle organization

signal transduction [inference]

intracellular signal transduction [inference]

cell cycle checkpoint signaling [inference]

mitotic cell cycle checkpoint signaling [inference]

mitotic spindle checkpoint signaling [inference]

mitotic spindle assembly checkpoint signaling

spindle checkpoint signaling [inference]

meiotic spindle checkpoint signaling [inference]

meiotic spindle assembly checkpoint signaling

spindle assembly checkpoint signaling [inference]

mitotic spindle checkpoint signaling [inference]

mitotic spindle assembly checkpoint signaling

meiotic cell cycle checkpoint signaling [inference]

meiotic spindle checkpoint signaling [inference]

meiotic spindle assembly checkpoint signaling

cell cycle process [inference]

spindle organization

mitotic spindle organization

chromosome segregation

nuclear chromosome segregation [inference]

meiotic chromosome segregation [inference]

female meiosis chromosome segregation

repair of kinetochore microtubule attachment defect [inference]

repair of mitotic kinetochore microtubule attachment defect

meiotic cell cycle process [inference]

meiotic cell cycle checkpoint signaling [inference]

meiotic spindle checkpoint signaling [inference]

meiotic spindle assembly checkpoint signaling

meiotic chromosome segregation [inference]

female meiosis chromosome segregation

mitotic cell cycle process [inference]

mitotic cell cycle checkpoint signaling [inference]

mitotic spindle checkpoint signaling [inference]

mitotic spindle assembly checkpoint signaling

repair of mitotic kinetochore microtubule attachment defect

microtubule cytoskeleton organization involved in mitosis [inference]

mitotic spindle organization

cellular process involved in reproduction in multicellular organism [inference]

female meiosis chromosome segregation

cellular localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to organelle [inference]

protein localization to chromosome [inference]

protein localization to chromosome, centromeric region [inference]

protein localization to kinetochore

protein localization to condensed chromosome [inference]

protein localization to kinetochore

protein localization to cytoskeleton [inference]

protein localization to microtubule cytoskeleton [inference]

protein localization to meiotic spindle [inference]

protein localization to meiotic spindle midzone

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

cytoskeleton organization [inference]

microtubule cytoskeleton organization [inference]

spindle organization

mitotic spindle organization

microtubule cytoskeleton organization involved in mitosis [inference]

mitotic spindle organization

reproductive process [inference]

cellular process involved in reproduction in multicellular organism [inference]

female meiosis chromosome segregation

meiotic cell cycle process [inference]

meiotic cell cycle checkpoint signaling [inference]

meiotic spindle checkpoint signaling [inference]

meiotic spindle assembly checkpoint signaling

meiotic chromosome segregation [inference]

female meiosis chromosome segregation

localization [inference]

macromolecule localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to organelle [inference]

protein localization to chromosome [inference]

protein localization to chromosome, centromeric region [inference]

protein localization to kinetochore

protein localization to condensed chromosome [inference]

protein localization to kinetochore

protein localization to cytoskeleton [inference]

protein localization to microtubule cytoskeleton [inference]

protein localization to meiotic spindle [inference]

protein localization to meiotic spindle midzone

cellular localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to organelle [inference]

protein localization to chromosome [inference]

protein localization to chromosome, centromeric region [inference]

protein localization to kinetochore

protein localization to condensed chromosome [inference]

protein localization to kinetochore

protein localization to cytoskeleton [inference]

protein localization to microtubule cytoskeleton [inference]

protein localization to meiotic spindle [inference]

protein localization to meiotic spindle midzone

biological regulation [inference]

regulation of biological process [inference]

regulation of signaling [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

positive regulation of SMAD protein signal transduction

positive regulation of intracellular signal transduction [inference]

positive regulation of SMAD protein signal transduction

regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

positive regulation of SMAD protein signal transduction

regulation of intracellular signal transduction [inference]

regulation of SMAD protein signal transduction [inference]

positive regulation of SMAD protein signal transduction

positive regulation of intracellular signal transduction [inference]

positive regulation of SMAD protein signal transduction

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

positive regulation of SMAD protein signal transduction

positive regulation of intracellular signal transduction [inference]

positive regulation of SMAD protein signal transduction

positive regulation of biological process [inference]

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

positive regulation of SMAD protein signal transduction

positive regulation of intracellular signal transduction [inference]

positive regulation of SMAD protein signal transduction

positive regulation of cellular process [inference]

positive regulation of cell population proliferation

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

positive regulation of SMAD protein signal transduction

positive regulation of intracellular signal transduction [inference]

positive regulation of SMAD protein signal transduction

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

positive regulation of SMAD protein signal transduction

positive regulation of intracellular signal transduction [inference]

positive regulation of SMAD protein signal transduction

negative regulation of biological process [inference]

negative regulation of cellular process [inference]

negative regulation of cell cycle [inference]

negative regulation of cell cycle process [inference]

negative regulation of mitotic nuclear division [inference]

negative regulation of mitotic metaphase/anaphase transition [inference]

mitotic spindle assembly checkpoint signaling

negative regulation of chromosome segregation [inference]

negative regulation of sister chromatid segregation [inference]

negative regulation of mitotic sister chromatid segregation [inference]

negative regulation of mitotic sister chromatid separation [inference]

negative regulation of mitotic metaphase/anaphase transition [inference]

mitotic spindle assembly checkpoint signaling

negative regulation of chromosome separation [inference]

negative regulation of meiotic chromosome separation [inference]

negative regulation of metaphase/anaphase transition of meiotic cell cycle [inference]

meiotic spindle checkpoint signaling [inference]

meiotic spindle assembly checkpoint signaling

negative regulation of mitotic sister chromatid separation [inference]

negative regulation of mitotic metaphase/anaphase transition [inference]

mitotic spindle assembly checkpoint signaling

negative regulation of cell cycle phase transition [inference]

cell cycle checkpoint signaling [inference]

mitotic cell cycle checkpoint signaling [inference]

mitotic spindle checkpoint signaling [inference]

mitotic spindle assembly checkpoint signaling

spindle checkpoint signaling [inference]

meiotic spindle checkpoint signaling [inference]

meiotic spindle assembly checkpoint signaling

spindle assembly checkpoint signaling [inference]

mitotic spindle checkpoint signaling [inference]

mitotic spindle assembly checkpoint signaling

meiotic cell cycle checkpoint signaling [inference]

meiotic spindle checkpoint signaling [inference]

meiotic spindle assembly checkpoint signaling

negative regulation of mitotic cell cycle phase transition [inference]

negative regulation of mitotic metaphase/anaphase transition [inference]

mitotic spindle assembly checkpoint signaling

negative regulation of meiotic cell cycle phase transition [inference]

negative regulation of metaphase/anaphase transition of meiotic cell cycle [inference]

meiotic spindle checkpoint signaling [inference]

meiotic spindle assembly checkpoint signaling

negative regulation of metaphase/anaphase transition of cell cycle [inference]

negative regulation of mitotic metaphase/anaphase transition [inference]

mitotic spindle assembly checkpoint signaling

negative regulation of metaphase/anaphase transition of meiotic cell cycle [inference]

meiotic spindle checkpoint signaling [inference]

meiotic spindle assembly checkpoint signaling

negative regulation of mitotic cell cycle [inference]

mitotic cell cycle checkpoint signaling [inference]

mitotic spindle checkpoint signaling [inference]

mitotic spindle assembly checkpoint signaling

negative regulation of mitotic nuclear division [inference]

negative regulation of mitotic metaphase/anaphase transition [inference]

mitotic spindle assembly checkpoint signaling

negative regulation of mitotic cell cycle phase transition [inference]

negative regulation of mitotic metaphase/anaphase transition [inference]

mitotic spindle assembly checkpoint signaling

negative regulation of meiotic cell cycle [inference]

negative regulation of meiotic cell cycle phase transition [inference]

negative regulation of metaphase/anaphase transition of meiotic cell cycle [inference]

meiotic spindle checkpoint signaling [inference]

meiotic spindle assembly checkpoint signaling

negative regulation of cellular component organization [inference]

negative regulation of organelle organization [inference]

negative regulation of nuclear division [inference]

negative regulation of mitotic nuclear division [inference]

negative regulation of mitotic metaphase/anaphase transition [inference]

mitotic spindle assembly checkpoint signaling

negative regulation of chromosome organization [inference]

negative regulation of sister chromatid segregation [inference]

negative regulation of mitotic sister chromatid segregation [inference]

negative regulation of mitotic sister chromatid separation [inference]

negative regulation of mitotic metaphase/anaphase transition [inference]

mitotic spindle assembly checkpoint signaling

negative regulation of reproductive process [inference]

negative regulation of meiotic cell cycle [inference]

negative regulation of meiotic cell cycle phase transition [inference]

negative regulation of metaphase/anaphase transition of meiotic cell cycle [inference]

meiotic spindle checkpoint signaling [inference]

meiotic spindle assembly checkpoint signaling

negative regulation of meiotic chromosome separation [inference]

negative regulation of metaphase/anaphase transition of meiotic cell cycle [inference]

meiotic spindle checkpoint signaling [inference]

meiotic spindle assembly checkpoint signaling

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

positive regulation of SMAD protein signal transduction

positive regulation of intracellular signal transduction [inference]

positive regulation of SMAD protein signal transduction

regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

positive regulation of SMAD protein signal transduction

regulation of intracellular signal transduction [inference]

regulation of SMAD protein signal transduction [inference]

positive regulation of SMAD protein signal transduction

positive regulation of intracellular signal transduction [inference]

positive regulation of SMAD protein signal transduction

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

positive regulation of SMAD protein signal transduction

positive regulation of intracellular signal transduction [inference]

positive regulation of SMAD protein signal transduction

regulation of cellular process [inference]

signal transduction [inference]

intracellular signal transduction [inference]

cell cycle checkpoint signaling [inference]

mitotic cell cycle checkpoint signaling [inference]

mitotic spindle checkpoint signaling [inference]

mitotic spindle assembly checkpoint signaling

spindle checkpoint signaling [inference]

meiotic spindle checkpoint signaling [inference]

meiotic spindle assembly checkpoint signaling

spindle assembly checkpoint signaling [inference]

mitotic spindle checkpoint signaling [inference]

mitotic spindle assembly checkpoint signaling

meiotic cell cycle checkpoint signaling [inference]

meiotic spindle checkpoint signaling [inference]

meiotic spindle assembly checkpoint signaling

regulation of cell communication [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

positive regulation of SMAD protein signal transduction

positive regulation of intracellular signal transduction [inference]

positive regulation of SMAD protein signal transduction

regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

positive regulation of SMAD protein signal transduction

regulation of intracellular signal transduction [inference]

regulation of SMAD protein signal transduction [inference]

positive regulation of SMAD protein signal transduction

positive regulation of intracellular signal transduction [inference]

positive regulation of SMAD protein signal transduction

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

positive regulation of SMAD protein signal transduction

positive regulation of intracellular signal transduction [inference]

positive regulation of SMAD protein signal transduction

regulation of cell population proliferation [inference]

positive regulation of cell population proliferation

positive regulation of cellular process [inference]

positive regulation of cell population proliferation

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

positive regulation of SMAD protein signal transduction

positive regulation of intracellular signal transduction [inference]

positive regulation of SMAD protein signal transduction

negative regulation of cellular process [inference]

negative regulation of cell cycle [inference]

negative regulation of cell cycle process [inference]

negative regulation of mitotic nuclear division [inference]

negative regulation of mitotic metaphase/anaphase transition [inference]

mitotic spindle assembly checkpoint signaling

negative regulation of chromosome segregation [inference]

negative regulation of sister chromatid segregation [inference]

negative regulation of mitotic sister chromatid segregation [inference]

negative regulation of mitotic sister chromatid separation [inference]

negative regulation of mitotic metaphase/anaphase transition [inference]

mitotic spindle assembly checkpoint signaling

negative regulation of chromosome separation [inference]

negative regulation of meiotic chromosome separation [inference]

negative regulation of metaphase/anaphase transition of meiotic cell cycle [inference]

meiotic spindle checkpoint signaling [inference]

meiotic spindle assembly checkpoint signaling

negative regulation of mitotic sister chromatid separation [inference]

negative regulation of mitotic metaphase/anaphase transition [inference]

mitotic spindle assembly checkpoint signaling

negative regulation of cell cycle phase transition [inference]

cell cycle checkpoint signaling [inference]

mitotic cell cycle checkpoint signaling [inference]

mitotic spindle checkpoint signaling [inference]

mitotic spindle assembly checkpoint signaling

spindle checkpoint signaling [inference]

meiotic spindle checkpoint signaling [inference]

meiotic spindle assembly checkpoint signaling

spindle assembly checkpoint signaling [inference]

mitotic spindle checkpoint signaling [inference]

mitotic spindle assembly checkpoint signaling

meiotic cell cycle checkpoint signaling [inference]

meiotic spindle checkpoint signaling [inference]

meiotic spindle assembly checkpoint signaling

negative regulation of mitotic cell cycle phase transition [inference]

negative regulation of mitotic metaphase/anaphase transition [inference]

mitotic spindle assembly checkpoint signaling

negative regulation of meiotic cell cycle phase transition [inference]

negative regulation of metaphase/anaphase transition of meiotic cell cycle [inference]

meiotic spindle checkpoint signaling [inference]

meiotic spindle assembly checkpoint signaling

negative regulation of metaphase/anaphase transition of cell cycle [inference]

negative regulation of mitotic metaphase/anaphase transition [inference]

mitotic spindle assembly checkpoint signaling

negative regulation of metaphase/anaphase transition of meiotic cell cycle [inference]

meiotic spindle checkpoint signaling [inference]

meiotic spindle assembly checkpoint signaling

negative regulation of mitotic cell cycle [inference]

mitotic cell cycle checkpoint signaling [inference]

mitotic spindle checkpoint signaling [inference]

mitotic spindle assembly checkpoint signaling

negative regulation of mitotic nuclear division [inference]

negative regulation of mitotic metaphase/anaphase transition [inference]

mitotic spindle assembly checkpoint signaling

negative regulation of mitotic cell cycle phase transition [inference]

negative regulation of mitotic metaphase/anaphase transition [inference]

mitotic spindle assembly checkpoint signaling

negative regulation of meiotic cell cycle [inference]

negative regulation of meiotic cell cycle phase transition [inference]

negative regulation of metaphase/anaphase transition of meiotic cell cycle [inference]

meiotic spindle checkpoint signaling [inference]

meiotic spindle assembly checkpoint signaling

negative regulation of cellular component organization [inference]

negative regulation of organelle organization [inference]

negative regulation of nuclear division [inference]

negative regulation of mitotic nuclear division [inference]

negative regulation of mitotic metaphase/anaphase transition [inference]

mitotic spindle assembly checkpoint signaling

negative regulation of chromosome organization [inference]

negative regulation of sister chromatid segregation [inference]

negative regulation of mitotic sister chromatid segregation [inference]

negative regulation of mitotic sister chromatid separation [inference]

negative regulation of mitotic metaphase/anaphase transition [inference]

mitotic spindle assembly checkpoint signaling

regulation of cellular component organization [inference]

regulation of organelle organization [inference]

negative regulation of organelle organization [inference]

negative regulation of nuclear division [inference]

negative regulation of mitotic nuclear division [inference]

negative regulation of mitotic metaphase/anaphase transition [inference]

mitotic spindle assembly checkpoint signaling

negative regulation of chromosome organization [inference]

negative regulation of sister chromatid segregation [inference]

negative regulation of mitotic sister chromatid segregation [inference]

negative regulation of mitotic sister chromatid separation [inference]

negative regulation of mitotic metaphase/anaphase transition [inference]

mitotic spindle assembly checkpoint signaling

regulation of chromosome organization [inference]

regulation of sister chromatid segregation [inference]

negative regulation of sister chromatid segregation [inference]

negative regulation of mitotic sister chromatid segregation [inference]

negative regulation of mitotic sister chromatid separation [inference]

negative regulation of mitotic metaphase/anaphase transition [inference]

mitotic spindle assembly checkpoint signaling

regulation of mitotic sister chromatid segregation [inference]

negative regulation of mitotic sister chromatid segregation [inference]

negative regulation of mitotic sister chromatid separation [inference]

negative regulation of mitotic metaphase/anaphase transition [inference]

mitotic spindle assembly checkpoint signaling

regulation of metaphase/anaphase transition of cell cycle [inference]

regulation of mitotic metaphase/anaphase transition [inference]

negative regulation of mitotic metaphase/anaphase transition [inference]

mitotic spindle assembly checkpoint signaling

negative regulation of metaphase/anaphase transition of cell cycle [inference]

negative regulation of mitotic metaphase/anaphase transition [inference]

mitotic spindle assembly checkpoint signaling

negative regulation of metaphase/anaphase transition of meiotic cell cycle [inference]

meiotic spindle checkpoint signaling [inference]

meiotic spindle assembly checkpoint signaling

regulation of metaphase/anaphase transition of meiotic cell cycle [inference]

negative regulation of metaphase/anaphase transition of meiotic cell cycle [inference]

meiotic spindle checkpoint signaling [inference]

meiotic spindle assembly checkpoint signaling

negative regulation of chromosome organization [inference]

negative regulation of sister chromatid segregation [inference]

negative regulation of mitotic sister chromatid segregation [inference]

negative regulation of mitotic sister chromatid separation [inference]

negative regulation of mitotic metaphase/anaphase transition [inference]

mitotic spindle assembly checkpoint signaling

regulation of nuclear division [inference]

regulation of mitotic nuclear division [inference]

negative regulation of mitotic nuclear division [inference]

negative regulation of mitotic metaphase/anaphase transition [inference]

mitotic spindle assembly checkpoint signaling

negative regulation of nuclear division [inference]

negative regulation of mitotic nuclear division [inference]

negative regulation of mitotic metaphase/anaphase transition [inference]

mitotic spindle assembly checkpoint signaling

negative regulation of cellular component organization [inference]

negative regulation of organelle organization [inference]

negative regulation of nuclear division [inference]

negative regulation of mitotic nuclear division [inference]

negative regulation of mitotic metaphase/anaphase transition [inference]

mitotic spindle assembly checkpoint signaling

negative regulation of chromosome organization [inference]

negative regulation of sister chromatid segregation [inference]

negative regulation of mitotic sister chromatid segregation [inference]

negative regulation of mitotic sister chromatid separation [inference]

negative regulation of mitotic metaphase/anaphase transition [inference]

mitotic spindle assembly checkpoint signaling

regulation of cell cycle [inference]

regulation of mitotic cell cycle [inference]

regulation of mitotic nuclear division [inference]

negative regulation of mitotic nuclear division [inference]

negative regulation of mitotic metaphase/anaphase transition [inference]

mitotic spindle assembly checkpoint signaling

negative regulation of mitotic cell cycle [inference]

mitotic cell cycle checkpoint signaling [inference]

mitotic spindle checkpoint signaling [inference]

mitotic spindle assembly checkpoint signaling

negative regulation of mitotic nuclear division [inference]

negative regulation of mitotic metaphase/anaphase transition [inference]

mitotic spindle assembly checkpoint signaling

negative regulation of mitotic cell cycle phase transition [inference]

negative regulation of mitotic metaphase/anaphase transition [inference]

mitotic spindle assembly checkpoint signaling

regulation of mitotic cell cycle phase transition [inference]

regulation of mitotic metaphase/anaphase transition [inference]

negative regulation of mitotic metaphase/anaphase transition [inference]

mitotic spindle assembly checkpoint signaling

negative regulation of mitotic cell cycle phase transition [inference]

negative regulation of mitotic metaphase/anaphase transition [inference]

mitotic spindle assembly checkpoint signaling

regulation of cell cycle process [inference]

regulation of mitotic nuclear division [inference]

negative regulation of mitotic nuclear division [inference]

negative regulation of mitotic metaphase/anaphase transition [inference]

mitotic spindle assembly checkpoint signaling

negative regulation of cell cycle process [inference]

negative regulation of mitotic nuclear division [inference]

negative regulation of mitotic metaphase/anaphase transition [inference]

mitotic spindle assembly checkpoint signaling

negative regulation of chromosome segregation [inference]

negative regulation of sister chromatid segregation [inference]

negative regulation of mitotic sister chromatid segregation [inference]

negative regulation of mitotic sister chromatid separation [inference]

negative regulation of mitotic metaphase/anaphase transition [inference]

mitotic spindle assembly checkpoint signaling

negative regulation of chromosome separation [inference]

negative regulation of meiotic chromosome separation [inference]

negative regulation of metaphase/anaphase transition of meiotic cell cycle [inference]

meiotic spindle checkpoint signaling [inference]

meiotic spindle assembly checkpoint signaling

negative regulation of mitotic sister chromatid separation [inference]

negative regulation of mitotic metaphase/anaphase transition [inference]

mitotic spindle assembly checkpoint signaling

negative regulation of cell cycle phase transition [inference]

cell cycle checkpoint signaling [inference]

mitotic cell cycle checkpoint signaling [inference]

mitotic spindle checkpoint signaling [inference]

mitotic spindle assembly checkpoint signaling

spindle checkpoint signaling [inference]

meiotic spindle checkpoint signaling [inference]

meiotic spindle assembly checkpoint signaling

spindle assembly checkpoint signaling [inference]

mitotic spindle checkpoint signaling [inference]

mitotic spindle assembly checkpoint signaling

meiotic cell cycle checkpoint signaling [inference]

meiotic spindle checkpoint signaling [inference]

meiotic spindle assembly checkpoint signaling

negative regulation of mitotic cell cycle phase transition [inference]

negative regulation of mitotic metaphase/anaphase transition [inference]

mitotic spindle assembly checkpoint signaling

negative regulation of meiotic cell cycle phase transition [inference]

negative regulation of metaphase/anaphase transition of meiotic cell cycle [inference]

meiotic spindle checkpoint signaling [inference]

meiotic spindle assembly checkpoint signaling

negative regulation of metaphase/anaphase transition of cell cycle [inference]

negative regulation of mitotic metaphase/anaphase transition [inference]

mitotic spindle assembly checkpoint signaling

negative regulation of metaphase/anaphase transition of meiotic cell cycle [inference]

meiotic spindle checkpoint signaling [inference]

meiotic spindle assembly checkpoint signaling

regulation of chromosome segregation [inference]

regulation of sister chromatid segregation [inference]

negative regulation of sister chromatid segregation [inference]

negative regulation of mitotic sister chromatid segregation [inference]

negative regulation of mitotic sister chromatid separation [inference]

negative regulation of mitotic metaphase/anaphase transition [inference]

mitotic spindle assembly checkpoint signaling

regulation of mitotic sister chromatid segregation [inference]

negative regulation of mitotic sister chromatid segregation [inference]

negative regulation of mitotic sister chromatid separation [inference]

negative regulation of mitotic metaphase/anaphase transition [inference]

mitotic spindle assembly checkpoint signaling

regulation of metaphase/anaphase transition of cell cycle [inference]

regulation of mitotic metaphase/anaphase transition [inference]

negative regulation of mitotic metaphase/anaphase transition [inference]

mitotic spindle assembly checkpoint signaling

negative regulation of metaphase/anaphase transition of cell cycle [inference]

negative regulation of mitotic metaphase/anaphase transition [inference]

mitotic spindle assembly checkpoint signaling

negative regulation of metaphase/anaphase transition of meiotic cell cycle [inference]

meiotic spindle checkpoint signaling [inference]

meiotic spindle assembly checkpoint signaling

regulation of metaphase/anaphase transition of meiotic cell cycle [inference]

negative regulation of metaphase/anaphase transition of meiotic cell cycle [inference]

meiotic spindle checkpoint signaling [inference]

meiotic spindle assembly checkpoint signaling

negative regulation of chromosome segregation [inference]

negative regulation of sister chromatid segregation [inference]

negative regulation of mitotic sister chromatid segregation [inference]

negative regulation of mitotic sister chromatid separation [inference]

negative regulation of mitotic metaphase/anaphase transition [inference]

mitotic spindle assembly checkpoint signaling

negative regulation of chromosome separation [inference]

negative regulation of meiotic chromosome separation [inference]

negative regulation of metaphase/anaphase transition of meiotic cell cycle [inference]

meiotic spindle checkpoint signaling [inference]

meiotic spindle assembly checkpoint signaling

negative regulation of mitotic sister chromatid separation [inference]

negative regulation of mitotic metaphase/anaphase transition [inference]

mitotic spindle assembly checkpoint signaling

regulation of chromosome separation [inference]

regulation of mitotic sister chromatid separation [inference]

negative regulation of mitotic sister chromatid separation [inference]

negative regulation of mitotic metaphase/anaphase transition [inference]

mitotic spindle assembly checkpoint signaling

regulation of meiotic chromosome separation [inference]

regulation of metaphase/anaphase transition of meiotic cell cycle [inference]

negative regulation of metaphase/anaphase transition of meiotic cell cycle [inference]

meiotic spindle checkpoint signaling [inference]

meiotic spindle assembly checkpoint signaling

negative regulation of meiotic chromosome separation [inference]

negative regulation of metaphase/anaphase transition of meiotic cell cycle [inference]

meiotic spindle checkpoint signaling [inference]

meiotic spindle assembly checkpoint signaling

negative regulation of chromosome separation [inference]

negative regulation of meiotic chromosome separation [inference]

negative regulation of metaphase/anaphase transition of meiotic cell cycle [inference]

meiotic spindle checkpoint signaling [inference]

meiotic spindle assembly checkpoint signaling

negative regulation of mitotic sister chromatid separation [inference]

negative regulation of mitotic metaphase/anaphase transition [inference]

mitotic spindle assembly checkpoint signaling

regulation of cell cycle phase transition [inference]

negative regulation of cell cycle phase transition [inference]

cell cycle checkpoint signaling [inference]

mitotic cell cycle checkpoint signaling [inference]

mitotic spindle checkpoint signaling [inference]

mitotic spindle assembly checkpoint signaling

spindle checkpoint signaling [inference]

meiotic spindle checkpoint signaling [inference]

meiotic spindle assembly checkpoint signaling

spindle assembly checkpoint signaling [inference]

mitotic spindle checkpoint signaling [inference]

mitotic spindle assembly checkpoint signaling

meiotic cell cycle checkpoint signaling [inference]

meiotic spindle checkpoint signaling [inference]

meiotic spindle assembly checkpoint signaling

negative regulation of mitotic cell cycle phase transition [inference]

negative regulation of mitotic metaphase/anaphase transition [inference]

mitotic spindle assembly checkpoint signaling

negative regulation of meiotic cell cycle phase transition [inference]

negative regulation of metaphase/anaphase transition of meiotic cell cycle [inference]

meiotic spindle checkpoint signaling [inference]

meiotic spindle assembly checkpoint signaling

negative regulation of metaphase/anaphase transition of cell cycle [inference]

negative regulation of mitotic metaphase/anaphase transition [inference]

mitotic spindle assembly checkpoint signaling

negative regulation of metaphase/anaphase transition of meiotic cell cycle [inference]

meiotic spindle checkpoint signaling [inference]

meiotic spindle assembly checkpoint signaling

regulation of mitotic cell cycle phase transition [inference]

regulation of mitotic metaphase/anaphase transition [inference]

negative regulation of mitotic metaphase/anaphase transition [inference]

mitotic spindle assembly checkpoint signaling

negative regulation of mitotic cell cycle phase transition [inference]

negative regulation of mitotic metaphase/anaphase transition [inference]

mitotic spindle assembly checkpoint signaling

regulation of meiotic cell cycle phase transition [inference]

negative regulation of meiotic cell cycle phase transition [inference]

negative regulation of metaphase/anaphase transition of meiotic cell cycle [inference]

meiotic spindle checkpoint signaling [inference]

meiotic spindle assembly checkpoint signaling

regulation of metaphase/anaphase transition of meiotic cell cycle [inference]

negative regulation of metaphase/anaphase transition of meiotic cell cycle [inference]

meiotic spindle checkpoint signaling [inference]

meiotic spindle assembly checkpoint signaling

regulation of metaphase/anaphase transition of cell cycle [inference]

regulation of mitotic metaphase/anaphase transition [inference]

negative regulation of mitotic metaphase/anaphase transition [inference]

mitotic spindle assembly checkpoint signaling

negative regulation of metaphase/anaphase transition of cell cycle [inference]

negative regulation of mitotic metaphase/anaphase transition [inference]

mitotic spindle assembly checkpoint signaling

negative regulation of metaphase/anaphase transition of meiotic cell cycle [inference]

meiotic spindle checkpoint signaling [inference]

meiotic spindle assembly checkpoint signaling

regulation of metaphase/anaphase transition of meiotic cell cycle [inference]

negative regulation of metaphase/anaphase transition of meiotic cell cycle [inference]

meiotic spindle checkpoint signaling [inference]

meiotic spindle assembly checkpoint signaling

negative regulation of cell cycle [inference]

negative regulation of cell cycle process [inference]

negative regulation of mitotic nuclear division [inference]

negative regulation of mitotic metaphase/anaphase transition [inference]

mitotic spindle assembly checkpoint signaling

negative regulation of chromosome segregation [inference]

negative regulation of sister chromatid segregation [inference]

negative regulation of mitotic sister chromatid segregation [inference]

negative regulation of mitotic sister chromatid separation [inference]

negative regulation of mitotic metaphase/anaphase transition [inference]

mitotic spindle assembly checkpoint signaling

negative regulation of chromosome separation [inference]

negative regulation of meiotic chromosome separation [inference]

negative regulation of metaphase/anaphase transition of meiotic cell cycle [inference]

meiotic spindle checkpoint signaling [inference]

meiotic spindle assembly checkpoint signaling

negative regulation of mitotic sister chromatid separation [inference]

negative regulation of mitotic metaphase/anaphase transition [inference]

mitotic spindle assembly checkpoint signaling

negative regulation of cell cycle phase transition [inference]

cell cycle checkpoint signaling [inference]

mitotic cell cycle checkpoint signaling [inference]

mitotic spindle checkpoint signaling [inference]

mitotic spindle assembly checkpoint signaling

spindle checkpoint signaling [inference]

meiotic spindle checkpoint signaling [inference]

meiotic spindle assembly checkpoint signaling

spindle assembly checkpoint signaling [inference]

mitotic spindle checkpoint signaling [inference]

mitotic spindle assembly checkpoint signaling

meiotic cell cycle checkpoint signaling [inference]

meiotic spindle checkpoint signaling [inference]

meiotic spindle assembly checkpoint signaling

negative regulation of mitotic cell cycle phase transition [inference]

negative regulation of mitotic metaphase/anaphase transition [inference]

mitotic spindle assembly checkpoint signaling

negative regulation of meiotic cell cycle phase transition [inference]

negative regulation of metaphase/anaphase transition of meiotic cell cycle [inference]

meiotic spindle checkpoint signaling [inference]

meiotic spindle assembly checkpoint signaling

negative regulation of metaphase/anaphase transition of cell cycle [inference]

negative regulation of mitotic metaphase/anaphase transition [inference]

mitotic spindle assembly checkpoint signaling

negative regulation of metaphase/anaphase transition of meiotic cell cycle [inference]

meiotic spindle checkpoint signaling [inference]

meiotic spindle assembly checkpoint signaling

negative regulation of mitotic cell cycle [inference]

mitotic cell cycle checkpoint signaling [inference]

mitotic spindle checkpoint signaling [inference]

mitotic spindle assembly checkpoint signaling

negative regulation of mitotic nuclear division [inference]

negative regulation of mitotic metaphase/anaphase transition [inference]

mitotic spindle assembly checkpoint signaling

negative regulation of mitotic cell cycle phase transition [inference]

negative regulation of mitotic metaphase/anaphase transition [inference]

mitotic spindle assembly checkpoint signaling

negative regulation of meiotic cell cycle [inference]

negative regulation of meiotic cell cycle phase transition [inference]

negative regulation of metaphase/anaphase transition of meiotic cell cycle [inference]

meiotic spindle checkpoint signaling [inference]

meiotic spindle assembly checkpoint signaling

regulation of meiotic cell cycle [inference]

negative regulation of meiotic cell cycle [inference]

negative regulation of meiotic cell cycle phase transition [inference]

negative regulation of metaphase/anaphase transition of meiotic cell cycle [inference]

meiotic spindle checkpoint signaling [inference]

meiotic spindle assembly checkpoint signaling

regulation of reproductive process [inference]

regulation of meiotic cell cycle [inference]

negative regulation of meiotic cell cycle [inference]

negative regulation of meiotic cell cycle phase transition [inference]

negative regulation of metaphase/anaphase transition of meiotic cell cycle [inference]

meiotic spindle checkpoint signaling [inference]

meiotic spindle assembly checkpoint signaling

regulation of meiotic cell cycle phase transition [inference]

negative regulation of meiotic cell cycle phase transition [inference]

negative regulation of metaphase/anaphase transition of meiotic cell cycle [inference]

meiotic spindle checkpoint signaling [inference]

meiotic spindle assembly checkpoint signaling

regulation of metaphase/anaphase transition of meiotic cell cycle [inference]

negative regulation of metaphase/anaphase transition of meiotic cell cycle [inference]

meiotic spindle checkpoint signaling [inference]

meiotic spindle assembly checkpoint signaling

regulation of meiotic chromosome separation [inference]

regulation of metaphase/anaphase transition of meiotic cell cycle [inference]

negative regulation of metaphase/anaphase transition of meiotic cell cycle [inference]

meiotic spindle checkpoint signaling [inference]

meiotic spindle assembly checkpoint signaling

negative regulation of meiotic chromosome separation [inference]

negative regulation of metaphase/anaphase transition of meiotic cell cycle [inference]

meiotic spindle checkpoint signaling [inference]

meiotic spindle assembly checkpoint signaling

negative regulation of reproductive process [inference]

negative regulation of meiotic cell cycle [inference]

negative regulation of meiotic cell cycle phase transition [inference]

negative regulation of metaphase/anaphase transition of meiotic cell cycle [inference]

meiotic spindle checkpoint signaling [inference]

meiotic spindle assembly checkpoint signaling

negative regulation of meiotic chromosome separation [inference]

negative regulation of metaphase/anaphase transition of meiotic cell cycle [inference]

meiotic spindle checkpoint signaling [inference]

meiotic spindle assembly checkpoint signaling

Displaying **all 5** entries
GO Term	Evidence Code	PMID
kinetochore	IBA
nucleus	IBA
cytoplasm	IDA	25468996
spindle	TAS	10366450
membrane	HDA	19946888

GO Hierarchy

cellular component

cellular anatomical entity [inference]

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

non-membrane-bounded organelle [inference]

intracellular non-membrane-bounded organelle [inference]

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

intracellular non-membrane-bounded organelle [inference]

supramolecular complex [inference]

kinetochore

Displaying entries **1 - 5** of 11 in total

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GO Term	Evidence Code	PMID
protein serine/threonine kinase activity	IDA	18243099 28441529
protein serine/threonine kinase activity	IBA
protein serine/threonine/tyrosine kinase activity	IBA
protein tyrosine kinase activity	IEA
protein binding	IPI	19273613 26068854

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

transferase activity, transferring phosphorus-containing groups [inference]

kinase activity [inference]

protein kinase activity [inference]

protein tyrosine kinase activity

histone kinase activity [inference]

histone H3 kinase activity [inference]

histone H3Y41 kinase activity

histone H2AX kinase activity [inference]

histone H2AXY142 kinase activity

protein serine kinase activity

phosphotransferase activity, alcohol group as acceptor [inference]

protein kinase activity [inference]

protein tyrosine kinase activity

histone kinase activity [inference]

histone H3 kinase activity [inference]

histone H3Y41 kinase activity

histone H2AX kinase activity [inference]

histone H2AXY142 kinase activity

protein serine kinase activity

catalytic activity, acting on a protein [inference]

protein kinase activity [inference]

protein tyrosine kinase activity

histone kinase activity [inference]

histone H3 kinase activity [inference]

histone H3Y41 kinase activity

histone H2AX kinase activity [inference]

histone H2AXY142 kinase activity

protein serine kinase activity

histone modifying activity [inference]

histone kinase activity [inference]

histone H3 kinase activity [inference]

histone H3Y41 kinase activity

histone H2AX kinase activity [inference]

histone H2AXY142 kinase activity

binding [inference]

protein binding

identical protein binding

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ion binding [inference]

anion binding [inference]

purine ribonucleoside triphosphate binding [inference]

ATP binding

kinetochore binding

organic cyclic compound binding [inference]

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

kinase

Functional Category

E: Amino acid transport and metabolism
G: Carbohydrate transport and metabolism
J: Translation, ribosomal structure and biogenesis

Displaying **all 9** entries
Gene Ontology
ATP binding
chromosome segregation
kinase activity
nucleotide binding
phosphorylation
protein localization to kinetochore
protein phosphorylation
protein serine/threonine/tyrosine kinase activity
transferase activity

Displaying **all 5** entries
InterPro
Protein kinase Mps1 family, catalytic domain
Protein kinase domain
Protein kinase, ATP binding site
Protein kinase-like domain superfamily
Serine/threonine-protein kinase, active site

Ortholog

Displaying entries **1 - 10** of 74 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Xenopus tropicalis	7272	Xenbase:XB-GENE-953775
Mus musculus	22137		MOUSE61157
Rattus norvegicus	315852		RATNO41194
Danio rerio	317763		DANRE11109
Pan troglodytes	462844		PANTR38600
Canis lupus familiaris	481895		CANLF02939
Bos taurus	524925		BOVIN35380
Macaca mulatta	718430		MACMU34022
Monodelphis domestica	100023737		MONDO11242
Equus caballus	100069586		HORSE00679

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

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OrthoDB (Group)

International Collaboration

Acknowledgements