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peptidase (mitochondrial processing) beta
Summary
- Gene Symbol
-
- Pmpcb
- Organism
- Mus musculus (house mouse)
Annotation
- Keyword
-
- Metal-binding
- Metalloprotease
- Mitochondrion
- Reference proteome
- Transit peptide
- Zinc
- Proteins
| UniProt | Protein Name |
|---|---|
| Q9CXT8 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| protein processing involved in protein targeting to mitochondrion | ||
| protein processing |
| GO Term | Evidence Code | PMID |
|---|---|---|
| mitochondrial inner membrane | ||
| mitochondrial processing peptidase complex | ||
| mitochondrion | ||
| mitochondrial matrix |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| metal ion binding | ||
| metalloendopeptidase activity | ||
| endopeptidase activity | ||
| metallopeptidase activity |
GO Hierarchy
OrthoDB (Group)
- Group level
- Rodentia
- Group Name
- mitochondrial-processing peptidase subunit beta
- Functional Category
-
- H: Coenzyme transport and metabolism
- I: Lipid transport and metabolism
- O: Posttranslational modification, protein turnover, chaperones
| Gene Ontology |
|---|
| metal ion binding |
| metalloendopeptidase activity |
| protein processing involved in protein targeting to mitochondrion |
| proteolysis |
| InterPro |
|---|
| Metalloenzyme, LuxS/M16 peptidase-like |
| Peptidase M16, C-terminal |
| Peptidase M16, N-terminal |
| Peptidase M16, zinc-binding site |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0060892 | late onset Parkinson's disease | |
| DOID:0070332 | multiple mitochondrial dysfunctions syndrome 6 |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 127194144 | 60746_0:001a36 | |||
| 127214406 | 109678_0:004f40 | |||
| 127678265 | 10129_0:000c04 | |||
| 128099189 | 564181_0:00440b | |||
| 129680907 | 48139_1:0021b0 | |||
| 130867098 | 269649_0:005201 | |||
| 131906588 | 42410_0:001202 |
