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SH3-domain GRB2-like (endophilin) interacting protein 1

Summary

Gene Symbol

Sgip1

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

73094

PubChem

73094

Alliance of Genome Resources

MGI:1920344

Annotation

Keyword

Alternative splicing
Coated pit
Endocytosis
Phosphoprotein
Reference proteome

Proteins

Displaying **all 2** entries
UniProt	Protein Name
Q3UGH4
Q8VD37	Endophilin-3-interacting protein

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **11 - 14** of 14 in total

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GO Term	Evidence Code	PMID
plasma membrane tubulation
positive regulation of eating behavior	ISO
positive regulation of feeding behavior	ISS
positive regulation of feeding behavior	ISO

GO Hierarchy

biological process

cellular process [inference]

vesicle-mediated transport [inference]

endocytosis [inference]

receptor-mediated endocytosis [inference]

clathrin-dependent endocytosis

presynaptic endocytosis [inference]

synaptic vesicle endocytosis

vesicle-mediated transport in synapse [inference]

presynaptic endocytosis [inference]

synaptic vesicle endocytosis

cellular component organization or biogenesis [inference]

cellular component organization [inference]

membrane organization [inference]

plasma membrane organization [inference]

plasma membrane tubulation

multicellular organismal process [inference]

multicellular organismal-level homeostasis [inference]

energy homeostasis

response to dietary excess

homeostatic process [inference]

multicellular organismal-level homeostasis [inference]

energy homeostasis

response to dietary excess

response to stimulus [inference]

response to external stimulus [inference]

response to extracellular stimulus [inference]

response to nutrient levels [inference]

response to dietary excess

localization [inference]

establishment of localization [inference]

transport [inference]

vesicle-mediated transport [inference]

endocytosis [inference]

receptor-mediated endocytosis [inference]

clathrin-dependent endocytosis

presynaptic endocytosis [inference]

synaptic vesicle endocytosis

vesicle-mediated transport in synapse [inference]

presynaptic endocytosis [inference]

synaptic vesicle endocytosis

import into cell [inference]

endocytosis [inference]

receptor-mediated endocytosis [inference]

clathrin-dependent endocytosis

presynaptic endocytosis [inference]

synaptic vesicle endocytosis

establishment of localization in cell [inference]

presynaptic endocytosis [inference]

synaptic vesicle endocytosis

biological regulation [inference]

regulation of biological process [inference]

regulation of localization [inference]

regulation of transport [inference]

positive regulation of transport [inference]

positive regulation of endocytosis [inference]

positive regulation of receptor-mediated endocytosis

regulation of vesicle-mediated transport [inference]

regulation of endocytosis [inference]

positive regulation of endocytosis [inference]

positive regulation of receptor-mediated endocytosis

regulation of receptor-mediated endocytosis [inference]

positive regulation of receptor-mediated endocytosis

regulation of growth [inference]

positive regulation of growth [inference]

positive regulation of developmental growth [inference]

positive regulation of multicellular organism growth

regulation of developmental growth [inference]

regulation of multicellular organism growth [inference]

positive regulation of multicellular organism growth

positive regulation of developmental growth [inference]

positive regulation of multicellular organism growth

positive regulation of biological process [inference]

positive regulation of growth [inference]

positive regulation of developmental growth [inference]

positive regulation of multicellular organism growth

positive regulation of cellular process [inference]

positive regulation of cellular component organization [inference]

positive regulation of endocytosis [inference]

positive regulation of receptor-mediated endocytosis

positive regulation of transport [inference]

positive regulation of endocytosis [inference]

positive regulation of receptor-mediated endocytosis

positive regulation of developmental process [inference]

positive regulation of developmental growth [inference]

positive regulation of multicellular organism growth

positive regulation of multicellular organismal process [inference]

positive regulation of multicellular organism growth

positive regulation of behavior [inference]

positive regulation of feeding behavior

positive regulation of eating behavior

regulation of developmental process [inference]

regulation of developmental growth [inference]

regulation of multicellular organism growth [inference]

positive regulation of multicellular organism growth

positive regulation of developmental growth [inference]

positive regulation of multicellular organism growth

positive regulation of developmental process [inference]

positive regulation of developmental growth [inference]

positive regulation of multicellular organism growth

regulation of cellular process [inference]

positive regulation of cellular process [inference]

positive regulation of cellular component organization [inference]

positive regulation of endocytosis [inference]

positive regulation of receptor-mediated endocytosis

regulation of cellular component organization [inference]

regulation of endocytosis [inference]

positive regulation of endocytosis [inference]

positive regulation of receptor-mediated endocytosis

regulation of receptor-mediated endocytosis [inference]

positive regulation of receptor-mediated endocytosis

positive regulation of cellular component organization [inference]

positive regulation of endocytosis [inference]

positive regulation of receptor-mediated endocytosis

regulation of vesicle-mediated transport [inference]

regulation of endocytosis [inference]

positive regulation of endocytosis [inference]

positive regulation of receptor-mediated endocytosis

regulation of receptor-mediated endocytosis [inference]

positive regulation of receptor-mediated endocytosis

regulation of multicellular organismal process [inference]

regulation of multicellular organism growth [inference]

positive regulation of multicellular organism growth

regulation of behavior [inference]

positive regulation of behavior [inference]

positive regulation of feeding behavior

positive regulation of eating behavior

regulation of feeding behavior [inference]

regulation of eating behavior [inference]

positive regulation of eating behavior

positive regulation of feeding behavior

positive regulation of eating behavior

positive regulation of multicellular organismal process [inference]

positive regulation of multicellular organism growth

positive regulation of behavior [inference]

positive regulation of feeding behavior

positive regulation of eating behavior

Displaying entries **1 - 5** of 10 in total

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GO Term	Evidence Code	PMID
cytoplasm	ISS
cytoplasm	ISO
plasma membrane	ISO
plasma membrane	IDA	17626015
clathrin-coated pit	ISO

GO Hierarchy

cellular component

protein-containing complex [inference]

membrane protein complex [inference]

AP-type membrane coat adaptor complex [inference]

clathrin adaptor complex [inference]

AP-2 adaptor complex

plasma membrane protein complex [inference]

AP-2 adaptor complex

cellular anatomical entity [inference]

cytoplasm

membrane [inference]

plasma membrane

plasma membrane region [inference]

clathrin-coated pit

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

coated vesicle [inference]

clathrin-coated vesicle

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

coated vesicle [inference]

clathrin-coated vesicle

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

coated vesicle [inference]

clathrin-coated vesicle

presynapse

Displaying entries **1 - 5** of 7 in total

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GO Term	Evidence Code	PMID
protein binding	IPI	17626015 19713939 21747946
phospholipid binding	IDA	17626015
microtubule binding	IDA	17626015
tubulin binding	ISO
tubulin binding	IPI	17626015

GO Hierarchy

molecular function

binding [inference]

protein binding

cytoskeletal protein binding [inference]

tubulin binding

microtubule binding

protein domain specific binding [inference]

SH3 domain binding

lipid binding [inference]

phospholipid binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Rodentia

Group Name

SH3-containing GRB2-like protein 3-interacting protein 1

Functional Category

C: Energy production and conversion
G: Carbohydrate transport and metabolism
M: Cell wall/membrane/envelope biogenesis
N: Cell motility

Displaying **all 3** entries
Gene Ontology
actin filament binding
actin filament polymerization
clathrin-dependent endocytosis

Displaying **all 4** entries
InterPro
AP-2 complex subunit mu, C-terminal superfamily
Mu homology domain
Muniscin, C-terminal
SGIP1, mu-homology domain

Ortholog

Displaying entries **21 - 30** of 59 in total

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Species	Gene ID	Orthologous MAtrix
Canis lupus familiaris	100856415	CANLF15622
Pan paniscus	100977614	PANPA01569
Papio anubis	101007844	PAPAN21397
Saimiri boliviensis boliviensis	101052182	SAIBB02819
Takifugu rubripes	101074080	TAKRU28472
Felis catus	101085907	FELCA21575
Ovis aries	101112175	SHEEP00414
Gorilla gorilla gorilla	101141674	GORGO19686
Octodon degus	101575446	OCTDE11292
Jaculus jaculus	101617820	JACJA13279