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Guidelines

MIRAGE

4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase

Summary

Gene Symbol

CCNA_01558

Organism

Caulobacter vibrioides NA1000

External Links

NCBI Gene: 7333233
PubChem: 7333233

Annotation

Keyword

Isomerase
Metal-binding
Reference proteome
Zinc

Proteins

Displaying 1 entry
UniProt	Protein Name
B8H5V5	5-keto-4-deoxyuronate isomerase DKI isomerase

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 3** entries
GO Term	Evidence Code	PMID
D-galacturonate catabolic process
D-glucuronate catabolic process
pectin catabolic process

GO Hierarchy

biological process

metabolic process [inference]

catabolic process [inference]

cellular catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

glucuronate catabolic process [inference]

D-glucuronate catabolic process

galacturonate catabolic process [inference]

D-galacturonate catabolic process

small molecule catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

glucuronate catabolic process [inference]

D-glucuronate catabolic process

galacturonate catabolic process [inference]

D-galacturonate catabolic process

monosaccharide catabolic process [inference]

D-galacturonate catabolic process

organic substance catabolic process [inference]

macromolecule catabolic process [inference]

polysaccharide catabolic process [inference]

pectin catabolic process

carbohydrate catabolic process [inference]

polysaccharide catabolic process [inference]

pectin catabolic process

monosaccharide catabolic process [inference]

D-galacturonate catabolic process

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

glucuronate catabolic process [inference]

D-glucuronate catabolic process

galacturonate catabolic process [inference]

D-galacturonate catabolic process

cellular metabolic process [inference]

organic acid metabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

glucuronate catabolic process [inference]

D-glucuronate catabolic process

galacturonate catabolic process [inference]

D-galacturonate catabolic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

uronic acid metabolic process [inference]

glucuronate metabolic process [inference]

glucuronate catabolic process [inference]

D-glucuronate catabolic process

D-glucuronate metabolic process [inference]

D-glucuronate catabolic process

galacturonate metabolic process [inference]

D-galacturonate metabolic process [inference]

D-galacturonate catabolic process

galacturonate catabolic process [inference]

D-galacturonate catabolic process

monocarboxylic acid catabolic process [inference]

glucuronate catabolic process [inference]

D-glucuronate catabolic process

galacturonate catabolic process [inference]

D-galacturonate catabolic process

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

glucuronate catabolic process [inference]

D-glucuronate catabolic process

galacturonate catabolic process [inference]

D-galacturonate catabolic process

cellular catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

glucuronate catabolic process [inference]

D-glucuronate catabolic process

galacturonate catabolic process [inference]

D-galacturonate catabolic process

primary metabolic process [inference]

carbohydrate metabolic process [inference]

polysaccharide metabolic process [inference]

polysaccharide catabolic process [inference]

pectin catabolic process

galacturonan metabolic process [inference]

pectin metabolic process [inference]

pectin catabolic process

monosaccharide metabolic process [inference]

monosaccharide catabolic process [inference]

D-galacturonate catabolic process

D-galacturonate metabolic process [inference]

D-galacturonate catabolic process

carbohydrate catabolic process [inference]

polysaccharide catabolic process [inference]

pectin catabolic process

monosaccharide catabolic process [inference]

D-galacturonate catabolic process

small molecule metabolic process [inference]

monosaccharide metabolic process [inference]

monosaccharide catabolic process [inference]

D-galacturonate catabolic process

D-galacturonate metabolic process [inference]

D-galacturonate catabolic process

organic acid metabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

glucuronate catabolic process [inference]

D-glucuronate catabolic process

galacturonate catabolic process [inference]

D-galacturonate catabolic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

uronic acid metabolic process [inference]

glucuronate metabolic process [inference]

glucuronate catabolic process [inference]

D-glucuronate catabolic process

D-glucuronate metabolic process [inference]

D-glucuronate catabolic process

galacturonate metabolic process [inference]

D-galacturonate metabolic process [inference]

D-galacturonate catabolic process

galacturonate catabolic process [inference]

D-galacturonate catabolic process

monocarboxylic acid catabolic process [inference]

glucuronate catabolic process [inference]

D-glucuronate catabolic process

galacturonate catabolic process [inference]

D-galacturonate catabolic process

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

glucuronate catabolic process [inference]

D-glucuronate catabolic process

galacturonate catabolic process [inference]

D-galacturonate catabolic process

small molecule catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

glucuronate catabolic process [inference]

D-glucuronate catabolic process

galacturonate catabolic process [inference]

D-galacturonate catabolic process

monosaccharide catabolic process [inference]

D-galacturonate catabolic process

organic substance metabolic process [inference]

carbohydrate metabolic process [inference]

polysaccharide metabolic process [inference]

polysaccharide catabolic process [inference]

pectin catabolic process

galacturonan metabolic process [inference]

pectin metabolic process [inference]

pectin catabolic process

monosaccharide metabolic process [inference]

monosaccharide catabolic process [inference]

D-galacturonate catabolic process

D-galacturonate metabolic process [inference]

D-galacturonate catabolic process

carbohydrate catabolic process [inference]

polysaccharide catabolic process [inference]

pectin catabolic process

monosaccharide catabolic process [inference]

D-galacturonate catabolic process

organic acid metabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

glucuronate catabolic process [inference]

D-glucuronate catabolic process

galacturonate catabolic process [inference]

D-galacturonate catabolic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

uronic acid metabolic process [inference]

glucuronate metabolic process [inference]

glucuronate catabolic process [inference]

D-glucuronate catabolic process

D-glucuronate metabolic process [inference]

D-glucuronate catabolic process

galacturonate metabolic process [inference]

D-galacturonate metabolic process [inference]

D-galacturonate catabolic process

galacturonate catabolic process [inference]

D-galacturonate catabolic process

monocarboxylic acid catabolic process [inference]

glucuronate catabolic process [inference]

D-glucuronate catabolic process

galacturonate catabolic process [inference]

D-galacturonate catabolic process

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

glucuronate catabolic process [inference]

D-glucuronate catabolic process

galacturonate catabolic process [inference]

D-galacturonate catabolic process

macromolecule metabolic process [inference]

polysaccharide metabolic process [inference]

polysaccharide catabolic process [inference]

pectin catabolic process

galacturonan metabolic process [inference]

pectin metabolic process [inference]

pectin catabolic process

macromolecule catabolic process [inference]

polysaccharide catabolic process [inference]

pectin catabolic process

organic substance catabolic process [inference]

macromolecule catabolic process [inference]

polysaccharide catabolic process [inference]

pectin catabolic process

carbohydrate catabolic process [inference]

polysaccharide catabolic process [inference]

pectin catabolic process

monosaccharide catabolic process [inference]

D-galacturonate catabolic process

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

glucuronate catabolic process [inference]

D-glucuronate catabolic process

galacturonate catabolic process [inference]

D-galacturonate catabolic process

cellular process [inference]

cellular metabolic process [inference]

organic acid metabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

glucuronate catabolic process [inference]

D-glucuronate catabolic process

galacturonate catabolic process [inference]

D-galacturonate catabolic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

uronic acid metabolic process [inference]

glucuronate metabolic process [inference]

glucuronate catabolic process [inference]

D-glucuronate catabolic process

D-glucuronate metabolic process [inference]

D-glucuronate catabolic process

galacturonate metabolic process [inference]

D-galacturonate metabolic process [inference]

D-galacturonate catabolic process

galacturonate catabolic process [inference]

D-galacturonate catabolic process

monocarboxylic acid catabolic process [inference]

glucuronate catabolic process [inference]

D-glucuronate catabolic process

galacturonate catabolic process [inference]

D-galacturonate catabolic process

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

glucuronate catabolic process [inference]

D-glucuronate catabolic process

galacturonate catabolic process [inference]

D-galacturonate catabolic process

cellular catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

glucuronate catabolic process [inference]

D-glucuronate catabolic process

galacturonate catabolic process [inference]

D-galacturonate catabolic process

Displaying **all 2** entries
GO Term	Evidence Code	PMID
zinc ion binding
4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase activity

GO Hierarchy

molecular function

catalytic activity [inference]

isomerase activity [inference]

intramolecular oxidoreductase activity [inference]

intramolecular oxidoreductase activity, interconverting aldoses and ketoses [inference]

4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase activity

binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding [inference]

transition metal ion binding [inference]

zinc ion binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Bacteria

Group Name

4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase

Functional Category

G: Carbohydrate transport and metabolism
K: Transcription
T: Signal transduction mechanisms

Displaying **all 8** entries
Gene Ontology
4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase activity
D-galacturonate catabolic process
D-glucuronate catabolic process
intramolecular oxidoreductase activity, interconverting aldoses and ketoses
isomerase activity
metal ion binding
pectin catabolic process
zinc ion binding

Displaying **all 5** entries
InterPro
5-keto 4-deoxyuronate isomerase
5-keto-4-deoxyuronate isomerase, N-terminal
KduI/IolB isomerase
RmlC-like cupin domain superfamily
RmlC-like jelly roll fold

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GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: December 8, 2025