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CD70 molecule

Summary

Gene Symbol

CD70

Organism

Sus scrofa (pig)

External Links

NCBI Gene: 733577
PubChem: 733577

Annotation

Keyword

Cell membrane
Disulfide bond
Glycoprotein
Reference proteome
Signal-anchor
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
Q3ZDR4	CD27 ligand

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 4** entries
GO Term	Evidence Code	PMID
immune response	IEA	22301074
tumor necrosis factor-mediated signaling pathway	IEA	30032202
T cell activation
adaptive immune memory response involving T cells and B cells

GO Hierarchy

biological process

immune system process [inference]

immune response

adaptive immune response [inference]

adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [inference]

adaptive immune memory response involving T cells and B cells

adaptive immune memory response [inference]

adaptive immune memory response involving T cells and B cells

leukocyte activation [inference]

lymphocyte activation [inference]

T cell activation

immunological memory process [inference]

adaptive immune memory response [inference]

adaptive immune memory response involving T cells and B cells

cellular process [inference]

cell activation [inference]

leukocyte activation [inference]

lymphocyte activation [inference]

T cell activation

signal transduction [inference]

cell surface receptor signaling pathway [inference]

cytokine-mediated signaling pathway [inference]

tumor necrosis factor-mediated signaling pathway

multicellular organismal process [inference]

cell activation [inference]

leukocyte activation [inference]

lymphocyte activation [inference]

T cell activation

response to stimulus [inference]

immune response

adaptive immune response [inference]

adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [inference]

adaptive immune memory response involving T cells and B cells

adaptive immune memory response [inference]

adaptive immune memory response involving T cells and B cells

biological regulation [inference]

regulation of biological process [inference]

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

cytokine-mediated signaling pathway [inference]

tumor necrosis factor-mediated signaling pathway

Displaying **all 2** entries
GO Term	Evidence Code	PMID
plasma membrane	IEA	30032202
extracellular exosome	IEA	30032202

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

extracellular vesicle [inference]

extracellular exosome

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

extracellular organelle [inference]

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

Displaying **all 2** entries
GO Term	Evidence Code	PMID
tumor necrosis factor receptor binding	IEA	22301074 30032202
receptor ligand activity

GO Hierarchy

molecular function

binding [inference]

protein binding [inference]

signaling receptor binding [inference]

cytokine receptor binding [inference]

tumor necrosis factor receptor superfamily binding [inference]

tumor necrosis factor receptor binding

receptor ligand activity

molecular function regulator activity [inference]

signaling receptor regulator activity [inference]

signaling receptor activator activity [inference]

receptor ligand activity

molecular function activator activity [inference]

signaling receptor activator activity [inference]

receptor ligand activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

CD70

Functional Category

E: Amino acid transport and metabolism
P: Inorganic ion transport and metabolism
T: Signal transduction mechanisms

Displaying **all 3** entries
Gene Ontology
immune response
tumor necrosis factor receptor binding
tumor necrosis factor-mediated signaling pathway

Displaying **all 3** entries
InterPro
CD70 antigen
Tumour necrosis factor domain
Tumour necrosis factor-like domain superfamily

Ortholog

Displaying entries **1 - 10** of 31 in total

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Species	Gene ID	Orthologous MAtrix
Homo sapiens	970	HUMAN40166
Mus musculus	21948	MOUSE20346
Rattus norvegicus	301132	RATNO43808
Bos taurus	522074	BOVIN32795
Macaca mulatta	701080	MACMU20795
Equus caballus	100065854	HORSE40371
Callithrix jacchus	100399409	CALJA23859
Pongo abelii	100444685	PONAB15093
Ailuropoda melanoleuca	100475352	AILME04010
Nomascus leucogenys	100595486	NOMLE00332

GlyTouCan

GlyComb

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UniCarb-DR

LM-GlycoRepo

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Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements