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mannosyl-oligosaccharide glucosidase

Summary

Gene Symbol

MOGS

Organism

Pan troglodytes (chimpanzee)

External Links

NCBI Gene: 740472
KEGG Gene ID: ptr:740472
PubChem: 740472

Annotation

Keyword

Endoplasmic reticulum
Glycoprotein
Glycosidase
Reference proteome
Signal-anchor
Transmembrane helix

Proteins

Displaying **all 2** entries
UniProt	Protein Name
H2QI63	Glucosidase I
A0A6D2WTP1	Glucosidase I

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 2** entries
GO Term	Evidence Code	PMID
oligosaccharide metabolic process	IEA	30032202
protein N-linked glycosylation	IEA	30032202

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation [inference]

protein N-linked glycosylation

primary metabolic process [inference]

carbohydrate metabolic process [inference]

oligosaccharide metabolic process

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation [inference]

protein N-linked glycosylation

glycosylation [inference]

macromolecule glycosylation [inference]

protein glycosylation [inference]

protein N-linked glycosylation

organic substance metabolic process [inference]

carbohydrate metabolic process [inference]

oligosaccharide metabolic process

macromolecule metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation [inference]

protein N-linked glycosylation

macromolecule modification [inference]

protein modification process [inference]

protein glycosylation [inference]

protein N-linked glycosylation

macromolecule glycosylation [inference]

protein glycosylation [inference]

protein N-linked glycosylation

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation [inference]

protein N-linked glycosylation

Displaying 1 entry
GO Term	Evidence Code	PMID
endoplasmic reticulum membrane	IEA	30032202

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

organelle membrane [inference]

endoplasmic reticulum membrane

Displaying 1 entry
GO Term	Evidence Code	PMID
Glc3Man9GlcNAc2 oligosaccharide glucosidase activity	IEA	30032202

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on glycosyl bonds [inference]

hydrolase activity, hydrolyzing O-glycosyl compounds [inference]

glucosidase activity [inference]

Glc3Man9GlcNAc2 oligosaccharide glucosidase activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Hominidae

Group Name

Glycosyl hydrolase family 63, N-terminal

Functional Category

G: Carbohydrate transport and metabolism
H: Coenzyme transport and metabolism
M: Cell wall/membrane/envelope biogenesis
V: Defense mechanisms

Displaying **all 4** entries
Gene Ontology
Glc3Man9GlcNAc2 oligosaccharide glucosidase activity
hydrolase activity, acting on glycosyl bonds
hydrolase activity
protein N-linked glycosylation

Displaying **all 6** entries
InterPro
Glycoside hydrolase family 63
Glycosyl hydrolase family 63, C-terminal
Glycosyl hydrolase family 63, N-terminal domain superfamily
Glycosyl hydrolase family 63, N-terminal
Six-hairpin glycosidase superfamily
Six-hairpin glycosidase-like superfamily

KEGG BRITE Database

Orthology

K01228

Name

mannosyl-oligosaccharide glucosidase [EC:3.2.1.106]

References

Reactions

Displaying 1 entry
KEGG Reaction	Enzyme	Acceptor	Product
R05979	3.2.1.106	G57930PW	G18948TG

Rhea

H₂O

β-D-glucose

Enzyme

3.2.1.106

PMID

Ortholog

Displaying entries **41 - 50** of 82 in total

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Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Chlorocebus sabaeus	103220027			CHLSB04184
Carlito syrichta	103266729			CARSF07196
Ursus maritimus	103671412			URSMA00406
Rhinopithecus roxellana	104674816			RHIRO32216
Pteropus vampyrus	105290731			PTEVA14696
Macaca nemestrina	105465296			MACNE01281
Mandrillus leucophaeus	105540197			MANLE16085
Cercocebus atys	105596862			CERAT38925
Aotus nancymaae	105717155			AOTNA15817
Propithecus coquereli	105821480			PROCO29683

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GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: December 9, 2024