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ERBB receptor feedback inhibitor 1

Summary

Gene Symbol

Errfi1

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

74155

PubChem

74155

Alliance of Genome Resources

MGI:1921405

Annotation

Keyword

Acetylation
Cell membrane
Cytoplasm
Nucleus
Phosphoprotein
Reference proteome
Tumor suppressor

Proteins

Displaying **all 2** entries
UniProt	Protein Name
Q99JZ7	Mitogen-inducible gene 6 protein homolog
Q3TK48

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 67 in total

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GO Term	Evidence Code	PMID
skeletal system development	IMP	17987665
liver development	IMP	22912762 28053990
tissue homeostasis	IMP	19439667
glucose metabolic process	IMP	28053990
protein phosphorylation	IDA	29843645

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein phosphorylation

biosynthetic process [inference]

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

gene expression

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

bile acid biosynthetic process

small molecule biosynthetic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

bile acid biosynthetic process

organic substance biosynthetic process [inference]

lipid biosynthetic process [inference]

steroid biosynthetic process [inference]

bile acid biosynthetic process

macromolecule biosynthetic process [inference]

gene expression

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

bile acid biosynthetic process

organic cyclic compound biosynthetic process [inference]

steroid biosynthetic process [inference]

bile acid biosynthetic process

organic hydroxy compound biosynthetic process [inference]

bile acid biosynthetic process

cellular metabolic process [inference]

organic acid metabolic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

bile acid biosynthetic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

bile acid metabolic process [inference]

bile acid biosynthetic process

monocarboxylic acid biosynthetic process [inference]

bile acid biosynthetic process

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

bile acid biosynthetic process

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phosphorylation [inference]

protein phosphorylation

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

gene expression

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

bile acid biosynthetic process

primary metabolic process [inference]

carbohydrate metabolic process [inference]

monosaccharide metabolic process [inference]

hexose metabolic process [inference]

glucose metabolic process

lipid metabolic process

steroid metabolic process [inference]

steroid biosynthetic process [inference]

bile acid biosynthetic process

bile acid metabolic process [inference]

bile acid biosynthetic process

sterol metabolic process [inference]

cholesterol metabolic process

lipid biosynthetic process [inference]

steroid biosynthetic process [inference]

bile acid biosynthetic process

protein metabolic process [inference]

protein modification process [inference]

protein phosphorylation

small molecule metabolic process [inference]

monosaccharide metabolic process [inference]

hexose metabolic process [inference]

glucose metabolic process

alcohol metabolic process [inference]

secondary alcohol metabolic process [inference]

cholesterol metabolic process

organic acid metabolic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

bile acid biosynthetic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

bile acid metabolic process [inference]

bile acid biosynthetic process

monocarboxylic acid biosynthetic process [inference]

bile acid biosynthetic process

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

bile acid biosynthetic process

small molecule biosynthetic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

bile acid biosynthetic process

organic substance metabolic process [inference]

carbohydrate metabolic process [inference]

monosaccharide metabolic process [inference]

hexose metabolic process [inference]

glucose metabolic process

organic acid metabolic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

bile acid biosynthetic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

bile acid metabolic process [inference]

bile acid biosynthetic process

monocarboxylic acid biosynthetic process [inference]

bile acid biosynthetic process

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

bile acid biosynthetic process

lipid metabolic process

steroid metabolic process [inference]

steroid biosynthetic process [inference]

bile acid biosynthetic process

bile acid metabolic process [inference]

bile acid biosynthetic process

sterol metabolic process [inference]

cholesterol metabolic process

lipid biosynthetic process [inference]

steroid biosynthetic process [inference]

bile acid biosynthetic process

macromolecule metabolic process [inference]

macromolecule biosynthetic process [inference]

gene expression

protein metabolic process [inference]

protein modification process [inference]

protein phosphorylation

macromolecule modification [inference]

protein modification process [inference]

protein phosphorylation

organic cyclic compound metabolic process [inference]

steroid metabolic process [inference]

steroid biosynthetic process [inference]

bile acid biosynthetic process

bile acid metabolic process [inference]

bile acid biosynthetic process

sterol metabolic process [inference]

cholesterol metabolic process

organic cyclic compound biosynthetic process [inference]

steroid biosynthetic process [inference]

bile acid biosynthetic process

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein phosphorylation

organic substance biosynthetic process [inference]

lipid biosynthetic process [inference]

steroid biosynthetic process [inference]

bile acid biosynthetic process

macromolecule biosynthetic process [inference]

gene expression

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

bile acid biosynthetic process

organic cyclic compound biosynthetic process [inference]

steroid biosynthetic process [inference]

bile acid biosynthetic process

organic hydroxy compound biosynthetic process [inference]

bile acid biosynthetic process

organic hydroxy compound metabolic process [inference]

alcohol metabolic process [inference]

secondary alcohol metabolic process [inference]

cholesterol metabolic process

bile acid metabolic process [inference]

bile acid biosynthetic process

sterol metabolic process [inference]

cholesterol metabolic process

organic hydroxy compound biosynthetic process [inference]

bile acid biosynthetic process

cellular process [inference]

cell cycle

signal transduction [inference]

cell surface receptor signaling pathway [inference]

enzyme-linked receptor protein signaling pathway [inference]

transmembrane receptor protein tyrosine kinase signaling pathway [inference]

ERBB signaling pathway [inference]

epidermal growth factor receptor signaling pathway

hormone-mediated signaling pathway [inference]

steroid hormone mediated signaling pathway [inference]

intracellular steroid hormone receptor signaling pathway [inference]

progesterone receptor signaling pathway

intracellular receptor signaling pathway [inference]

intracellular steroid hormone receptor signaling pathway [inference]

progesterone receptor signaling pathway

intracellular signal transduction [inference]

cell death [inference]

programmed cell death [inference]

apoptotic process

cell population proliferation [inference]

cellular metabolic process [inference]

organic acid metabolic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

bile acid biosynthetic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

bile acid metabolic process [inference]

bile acid biosynthetic process

monocarboxylic acid biosynthetic process [inference]

bile acid biosynthetic process

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

bile acid biosynthetic process

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phosphorylation [inference]

protein phosphorylation

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

gene expression

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

bile acid biosynthetic process

cell motility [inference]

cell migration

cellular localization [inference]

localization within membrane [inference]

protein localization to membrane [inference]

protein localization to plasma membrane

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to membrane [inference]

protein localization to plasma membrane

protein localization to cell periphery [inference]

protein localization to plasma membrane

cellular response to stimulus [inference]

cellular response to stress [inference]

stress-activated protein kinase signaling cascade

reproductive process [inference]

developmental process involved in reproduction [inference]

oviduct epithelium development [inference]

uterine epithelium development

reproductive structure development [inference]

uterus development

embryo implantation

multicellular organismal process [inference]

multicellular organismal-level homeostasis [inference]

anatomical structure homeostasis [inference]

tissue homeostasis

developmental process [inference]

developmental process involved in reproduction [inference]

oviduct epithelium development [inference]

uterine epithelium development

reproductive structure development [inference]

uterus development

anatomical structure morphogenesis [inference]

animal organ morphogenesis [inference]

skin morphogenesis

limb joint morphogenesis

anatomical structure development [inference]

tissue development [inference]

epithelium development

oviduct epithelium development [inference]

uterine epithelium development

lung epithelium development

connective tissue development [inference]

adipose tissue development [inference]

fat pad development

lung alveolus development

animal organ development [inference]

skin development

gland development [inference]

liver development

reproductive structure development [inference]

uterus development

system development [inference]

skeletal system development

vasculature development [inference]

lung vasculature development

homeostatic process [inference]

multicellular organismal-level homeostasis [inference]

anatomical structure homeostasis [inference]

tissue homeostasis

chemical homeostasis [inference]

lipid homeostasis [inference]

sterol homeostasis [inference]

cholesterol homeostasis

response to stimulus [inference]

response to stress [inference]

cellular response to stress [inference]

stress-activated protein kinase signaling cascade

response to endogenous stimulus [inference]

response to hormone [inference]

response to peptide hormone [inference]

response to insulin

response to steroid hormone

response to progesterone

response to chemical [inference]

response to xenobiotic stimulus

response to organic substance [inference]

response to hormone [inference]

response to peptide hormone [inference]

response to insulin

response to steroid hormone

response to progesterone

response to organonitrogen compound [inference]

response to peptide [inference]

response to peptide hormone [inference]

response to insulin

response to organic cyclic compound [inference]

response to estradiol

response to steroid hormone

response to progesterone

response to lipid [inference]

response to estradiol

response to steroid hormone

response to progesterone

response to 1-oleoyl-sn-glycerol 3-phosphate

response to organophosphorus [inference]

response to 1-oleoyl-sn-glycerol 3-phosphate

response to ketone [inference]

response to progesterone

response to nitrogen compound [inference]

response to organonitrogen compound [inference]

response to peptide [inference]

response to peptide hormone [inference]

response to insulin

response to oxygen-containing compound [inference]

response to estradiol

response to peptide [inference]

response to peptide hormone [inference]

response to insulin

response to ketone [inference]

response to progesterone

response to 1-oleoyl-sn-glycerol 3-phosphate

cellular response to stimulus [inference]

cellular response to stress [inference]

stress-activated protein kinase signaling cascade

localization [inference]

macromolecule localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to membrane [inference]

protein localization to plasma membrane

protein localization to cell periphery [inference]

protein localization to plasma membrane

cellular localization [inference]

localization within membrane [inference]

protein localization to membrane [inference]

protein localization to plasma membrane

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to membrane [inference]

protein localization to plasma membrane

protein localization to cell periphery [inference]

protein localization to plasma membrane

biological regulation [inference]

regulation of biological process [inference]

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of interleukin-1 production [inference]

negative regulation of interleukin-1 beta production

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor production

negative regulation of collagen biosynthetic process

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

negative regulation of cytokine production [inference]

negative regulation of interleukin-1 production [inference]

negative regulation of interleukin-1 beta production

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor production

regulation of interleukin-1 production [inference]

regulation of interleukin-1 beta production [inference]

negative regulation of interleukin-1 beta production

negative regulation of interleukin-1 production [inference]

negative regulation of interleukin-1 beta production

regulation of tumor necrosis factor superfamily cytokine production [inference]

regulation of tumor necrosis factor production [inference]

negative regulation of tumor necrosis factor production

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor production

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of interleukin-1 production [inference]

negative regulation of interleukin-1 beta production

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor production

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of interleukin-1 production [inference]

negative regulation of interleukin-1 beta production

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor production

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of interleukin-1 production [inference]

negative regulation of interleukin-1 beta production

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor production

regulation of collagen biosynthetic process [inference]

negative regulation of collagen biosynthetic process

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of interleukin-1 production [inference]

negative regulation of interleukin-1 beta production

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor production

negative regulation of collagen biosynthetic process

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of interleukin-1 production [inference]

negative regulation of interleukin-1 beta production

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor production

negative regulation of protein metabolic process [inference]

negative regulation of protein modification process [inference]

negative regulation of protein phosphorylation [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein kinase activity by regulation of protein phosphorylation

negative regulation of protein tyrosine kinase activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

negative regulation of protein autophosphorylation

negative regulation of peptidyl-tyrosine phosphorylation

negative regulation of protein tyrosine kinase activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

negative regulation of collagen metabolic process [inference]

negative regulation of collagen biosynthetic process

negative regulation of cellular metabolic process [inference]

negative regulation of phosphorus metabolic process [inference]

negative regulation of phosphate metabolic process [inference]

negative regulation of phosphorylation [inference]

negative regulation of protein phosphorylation [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein kinase activity by regulation of protein phosphorylation

negative regulation of protein tyrosine kinase activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

negative regulation of protein autophosphorylation

negative regulation of peptidyl-tyrosine phosphorylation

negative regulation of protein tyrosine kinase activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

negative regulation of kinase activity [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein kinase activity by regulation of protein phosphorylation

negative regulation of protein tyrosine kinase activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of interleukin-1 production [inference]

negative regulation of interleukin-1 beta production

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor production

negative regulation of nitrogen compound metabolic process [inference]

negative regulation of protein metabolic process [inference]

negative regulation of protein modification process [inference]

negative regulation of protein phosphorylation [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein kinase activity by regulation of protein phosphorylation

negative regulation of protein tyrosine kinase activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

negative regulation of protein autophosphorylation

negative regulation of peptidyl-tyrosine phosphorylation

negative regulation of protein tyrosine kinase activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

regulation of collagen metabolic process [inference]

negative regulation of collagen metabolic process [inference]

negative regulation of collagen biosynthetic process

regulation of collagen biosynthetic process [inference]

negative regulation of collagen biosynthetic process

regulation of cellular metabolic process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of phosphorus metabolic process [inference]

negative regulation of phosphate metabolic process [inference]

negative regulation of phosphorylation [inference]

negative regulation of protein phosphorylation [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein kinase activity by regulation of protein phosphorylation

negative regulation of protein tyrosine kinase activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

negative regulation of protein autophosphorylation

negative regulation of peptidyl-tyrosine phosphorylation

negative regulation of protein tyrosine kinase activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

negative regulation of kinase activity [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein kinase activity by regulation of protein phosphorylation

negative regulation of protein tyrosine kinase activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of interleukin-1 production [inference]

negative regulation of interleukin-1 beta production

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor production

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

negative regulation of cytokine production [inference]

negative regulation of interleukin-1 production [inference]

negative regulation of interleukin-1 beta production

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor production

regulation of interleukin-1 production [inference]

regulation of interleukin-1 beta production [inference]

negative regulation of interleukin-1 beta production

negative regulation of interleukin-1 production [inference]

negative regulation of interleukin-1 beta production

regulation of tumor necrosis factor superfamily cytokine production [inference]

regulation of tumor necrosis factor production [inference]

negative regulation of tumor necrosis factor production

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor production

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of interleukin-1 production [inference]

negative regulation of interleukin-1 beta production

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor production

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of interleukin-1 production [inference]

negative regulation of interleukin-1 beta production

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor production

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of interleukin-1 production [inference]

negative regulation of interleukin-1 beta production

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor production

regulation of phosphorus metabolic process [inference]

negative regulation of phosphorus metabolic process [inference]

negative regulation of phosphate metabolic process [inference]

negative regulation of phosphorylation [inference]

negative regulation of protein phosphorylation [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein kinase activity by regulation of protein phosphorylation

negative regulation of protein tyrosine kinase activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

negative regulation of protein autophosphorylation

negative regulation of peptidyl-tyrosine phosphorylation

negative regulation of protein tyrosine kinase activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

negative regulation of kinase activity [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein kinase activity by regulation of protein phosphorylation

negative regulation of protein tyrosine kinase activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

regulation of phosphate metabolic process [inference]

regulation of phosphorylation [inference]

regulation of protein phosphorylation [inference]

negative regulation of protein phosphorylation [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein kinase activity by regulation of protein phosphorylation

negative regulation of protein tyrosine kinase activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

negative regulation of protein autophosphorylation

negative regulation of peptidyl-tyrosine phosphorylation

negative regulation of protein tyrosine kinase activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

regulation of protein autophosphorylation [inference]

negative regulation of protein autophosphorylation

regulation of protein kinase activity [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein kinase activity by regulation of protein phosphorylation

negative regulation of protein tyrosine kinase activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

regulation of protein tyrosine kinase activity

regulation of epidermal growth factor-activated receptor activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

negative regulation of protein tyrosine kinase activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

regulation of peptidyl-tyrosine phosphorylation [inference]

negative regulation of peptidyl-tyrosine phosphorylation

negative regulation of protein tyrosine kinase activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

regulation of protein tyrosine kinase activity

regulation of epidermal growth factor-activated receptor activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

negative regulation of protein tyrosine kinase activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

negative regulation of phosphorylation [inference]

negative regulation of protein phosphorylation [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein kinase activity by regulation of protein phosphorylation

negative regulation of protein tyrosine kinase activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

negative regulation of protein autophosphorylation

negative regulation of peptidyl-tyrosine phosphorylation

negative regulation of protein tyrosine kinase activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

negative regulation of kinase activity [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein kinase activity by regulation of protein phosphorylation

negative regulation of protein tyrosine kinase activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

regulation of kinase activity [inference]

negative regulation of kinase activity [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein kinase activity by regulation of protein phosphorylation

negative regulation of protein tyrosine kinase activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

regulation of protein kinase activity [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein kinase activity by regulation of protein phosphorylation

negative regulation of protein tyrosine kinase activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

regulation of protein tyrosine kinase activity

regulation of epidermal growth factor-activated receptor activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

negative regulation of protein tyrosine kinase activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

negative regulation of phosphate metabolic process [inference]

negative regulation of phosphorylation [inference]

negative regulation of protein phosphorylation [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein kinase activity by regulation of protein phosphorylation

negative regulation of protein tyrosine kinase activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

negative regulation of protein autophosphorylation

negative regulation of peptidyl-tyrosine phosphorylation

negative regulation of protein tyrosine kinase activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

negative regulation of kinase activity [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein kinase activity by regulation of protein phosphorylation

negative regulation of protein tyrosine kinase activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

regulation of nitrogen compound metabolic process [inference]

negative regulation of nitrogen compound metabolic process [inference]

negative regulation of protein metabolic process [inference]

negative regulation of protein modification process [inference]

negative regulation of protein phosphorylation [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein kinase activity by regulation of protein phosphorylation

negative regulation of protein tyrosine kinase activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

negative regulation of protein autophosphorylation

negative regulation of peptidyl-tyrosine phosphorylation

negative regulation of protein tyrosine kinase activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

regulation of protein metabolic process [inference]

regulation of protein modification process [inference]

regulation of protein phosphorylation [inference]

negative regulation of protein phosphorylation [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein kinase activity by regulation of protein phosphorylation

negative regulation of protein tyrosine kinase activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

negative regulation of protein autophosphorylation

negative regulation of peptidyl-tyrosine phosphorylation

negative regulation of protein tyrosine kinase activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

regulation of protein autophosphorylation [inference]

negative regulation of protein autophosphorylation

regulation of protein kinase activity [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein kinase activity by regulation of protein phosphorylation

negative regulation of protein tyrosine kinase activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

regulation of protein tyrosine kinase activity

regulation of epidermal growth factor-activated receptor activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

negative regulation of protein tyrosine kinase activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

regulation of peptidyl-tyrosine phosphorylation [inference]

negative regulation of peptidyl-tyrosine phosphorylation

negative regulation of protein tyrosine kinase activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

regulation of protein tyrosine kinase activity

regulation of epidermal growth factor-activated receptor activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

negative regulation of protein tyrosine kinase activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

negative regulation of protein modification process [inference]

negative regulation of protein phosphorylation [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein kinase activity by regulation of protein phosphorylation

negative regulation of protein tyrosine kinase activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

negative regulation of protein autophosphorylation

negative regulation of peptidyl-tyrosine phosphorylation

negative regulation of protein tyrosine kinase activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

negative regulation of protein metabolic process [inference]

negative regulation of protein modification process [inference]

negative regulation of protein phosphorylation [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein kinase activity by regulation of protein phosphorylation

negative regulation of protein tyrosine kinase activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

negative regulation of protein autophosphorylation

negative regulation of peptidyl-tyrosine phosphorylation

negative regulation of protein tyrosine kinase activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

negative regulation of cytokine production [inference]

negative regulation of interleukin-1 production [inference]

negative regulation of interleukin-1 beta production

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor production

regulation of interleukin-1 production [inference]

regulation of interleukin-1 beta production [inference]

negative regulation of interleukin-1 beta production

negative regulation of interleukin-1 production [inference]

negative regulation of interleukin-1 beta production

regulation of tumor necrosis factor superfamily cytokine production [inference]

regulation of tumor necrosis factor production [inference]

negative regulation of tumor necrosis factor production

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor production

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of interleukin-1 production [inference]

negative regulation of interleukin-1 beta production

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor production

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of interleukin-1 production [inference]

negative regulation of interleukin-1 beta production

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor production

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of interleukin-1 production [inference]

negative regulation of interleukin-1 beta production

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor production

negative regulation of protein metabolic process [inference]

negative regulation of protein modification process [inference]

negative regulation of protein phosphorylation [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein kinase activity by regulation of protein phosphorylation

negative regulation of protein tyrosine kinase activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

negative regulation of protein autophosphorylation

negative regulation of peptidyl-tyrosine phosphorylation

negative regulation of protein tyrosine kinase activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

regulation of protein metabolic process [inference]

regulation of protein modification process [inference]

regulation of protein phosphorylation [inference]

negative regulation of protein phosphorylation [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein kinase activity by regulation of protein phosphorylation

negative regulation of protein tyrosine kinase activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

negative regulation of protein autophosphorylation

negative regulation of peptidyl-tyrosine phosphorylation

negative regulation of protein tyrosine kinase activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

regulation of protein autophosphorylation [inference]

negative regulation of protein autophosphorylation

regulation of protein kinase activity [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein kinase activity by regulation of protein phosphorylation

negative regulation of protein tyrosine kinase activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

regulation of protein tyrosine kinase activity

regulation of epidermal growth factor-activated receptor activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

negative regulation of protein tyrosine kinase activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

regulation of peptidyl-tyrosine phosphorylation [inference]

negative regulation of peptidyl-tyrosine phosphorylation

negative regulation of protein tyrosine kinase activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

regulation of protein tyrosine kinase activity

regulation of epidermal growth factor-activated receptor activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

negative regulation of protein tyrosine kinase activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

negative regulation of protein modification process [inference]

negative regulation of protein phosphorylation [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein kinase activity by regulation of protein phosphorylation

negative regulation of protein tyrosine kinase activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

negative regulation of protein autophosphorylation

negative regulation of peptidyl-tyrosine phosphorylation

negative regulation of protein tyrosine kinase activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

negative regulation of protein metabolic process [inference]

negative regulation of protein modification process [inference]

negative regulation of protein phosphorylation [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein kinase activity by regulation of protein phosphorylation

negative regulation of protein tyrosine kinase activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

negative regulation of protein autophosphorylation

negative regulation of peptidyl-tyrosine phosphorylation

negative regulation of protein tyrosine kinase activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

regulation of primary metabolic process [inference]

regulation of protein metabolic process [inference]

regulation of protein modification process [inference]

regulation of protein phosphorylation [inference]

negative regulation of protein phosphorylation [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein kinase activity by regulation of protein phosphorylation

negative regulation of protein tyrosine kinase activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

negative regulation of protein autophosphorylation

negative regulation of peptidyl-tyrosine phosphorylation

negative regulation of protein tyrosine kinase activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

regulation of protein autophosphorylation [inference]

negative regulation of protein autophosphorylation

regulation of protein kinase activity [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein kinase activity by regulation of protein phosphorylation

negative regulation of protein tyrosine kinase activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

regulation of protein tyrosine kinase activity

regulation of epidermal growth factor-activated receptor activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

negative regulation of protein tyrosine kinase activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

regulation of peptidyl-tyrosine phosphorylation [inference]

negative regulation of peptidyl-tyrosine phosphorylation

negative regulation of protein tyrosine kinase activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

regulation of protein tyrosine kinase activity

regulation of epidermal growth factor-activated receptor activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

negative regulation of protein tyrosine kinase activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

negative regulation of protein modification process [inference]

negative regulation of protein phosphorylation [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein kinase activity by regulation of protein phosphorylation

negative regulation of protein tyrosine kinase activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

negative regulation of protein autophosphorylation

negative regulation of peptidyl-tyrosine phosphorylation

negative regulation of protein tyrosine kinase activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

negative regulation of protein metabolic process [inference]

negative regulation of protein modification process [inference]

negative regulation of protein phosphorylation [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein kinase activity by regulation of protein phosphorylation

negative regulation of protein tyrosine kinase activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

negative regulation of protein autophosphorylation

negative regulation of peptidyl-tyrosine phosphorylation

negative regulation of protein tyrosine kinase activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

regulation of signaling [inference]

regulation of signal transduction [inference]

negative regulation of signal transduction [inference]

negative regulation of ERBB signaling pathway [inference]

negative regulation of epidermal growth factor receptor signaling pathway

negative regulation of epidermal growth factor-activated receptor activity

negative regulation of intracellular signal transduction [inference]

negative regulation of MAPK cascade [inference]

negative regulation of ERK1 and ERK2 cascade

regulation of signaling receptor activity

regulation of epidermal growth factor-activated receptor activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

negative regulation of signaling receptor activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

regulation of ERBB signaling pathway [inference]

regulation of epidermal growth factor receptor signaling pathway [inference]

negative regulation of epidermal growth factor receptor signaling pathway

negative regulation of epidermal growth factor-activated receptor activity

negative regulation of ERBB signaling pathway [inference]

negative regulation of epidermal growth factor receptor signaling pathway

negative regulation of epidermal growth factor-activated receptor activity

regulation of intracellular signal transduction [inference]

regulation of MAPK cascade [inference]

negative regulation of MAPK cascade [inference]

negative regulation of ERK1 and ERK2 cascade

regulation of ERK1 and ERK2 cascade [inference]

negative regulation of ERK1 and ERK2 cascade

negative regulation of intracellular signal transduction [inference]

negative regulation of MAPK cascade [inference]

negative regulation of ERK1 and ERK2 cascade

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of ERBB signaling pathway [inference]

negative regulation of epidermal growth factor receptor signaling pathway

negative regulation of epidermal growth factor-activated receptor activity

negative regulation of intracellular signal transduction [inference]

negative regulation of MAPK cascade [inference]

negative regulation of ERK1 and ERK2 cascade

negative regulation of biological process [inference]

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of interleukin-1 production [inference]

negative regulation of interleukin-1 beta production

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor production

negative regulation of collagen biosynthetic process

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of interleukin-1 production [inference]

negative regulation of interleukin-1 beta production

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor production

negative regulation of protein metabolic process [inference]

negative regulation of protein modification process [inference]

negative regulation of protein phosphorylation [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein kinase activity by regulation of protein phosphorylation

negative regulation of protein tyrosine kinase activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

negative regulation of protein autophosphorylation

negative regulation of peptidyl-tyrosine phosphorylation

negative regulation of protein tyrosine kinase activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

negative regulation of collagen metabolic process [inference]

negative regulation of collagen biosynthetic process

negative regulation of cellular metabolic process [inference]

negative regulation of phosphorus metabolic process [inference]

negative regulation of phosphate metabolic process [inference]

negative regulation of phosphorylation [inference]

negative regulation of protein phosphorylation [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein kinase activity by regulation of protein phosphorylation

negative regulation of protein tyrosine kinase activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

negative regulation of protein autophosphorylation

negative regulation of peptidyl-tyrosine phosphorylation

negative regulation of protein tyrosine kinase activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

negative regulation of kinase activity [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein kinase activity by regulation of protein phosphorylation

negative regulation of protein tyrosine kinase activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of interleukin-1 production [inference]

negative regulation of interleukin-1 beta production

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor production

negative regulation of nitrogen compound metabolic process [inference]

negative regulation of protein metabolic process [inference]

negative regulation of protein modification process [inference]

negative regulation of protein phosphorylation [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein kinase activity by regulation of protein phosphorylation

negative regulation of protein tyrosine kinase activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

negative regulation of protein autophosphorylation

negative regulation of peptidyl-tyrosine phosphorylation

negative regulation of protein tyrosine kinase activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of ERBB signaling pathway [inference]

negative regulation of epidermal growth factor receptor signaling pathway

negative regulation of epidermal growth factor-activated receptor activity

negative regulation of intracellular signal transduction [inference]

negative regulation of MAPK cascade [inference]

negative regulation of ERK1 and ERK2 cascade

negative regulation of cellular process [inference]

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of ERBB signaling pathway [inference]

negative regulation of epidermal growth factor receptor signaling pathway

negative regulation of epidermal growth factor-activated receptor activity

negative regulation of intracellular signal transduction [inference]

negative regulation of MAPK cascade [inference]

negative regulation of ERK1 and ERK2 cascade

negative regulation of cellular metabolic process [inference]

negative regulation of phosphorus metabolic process [inference]

negative regulation of phosphate metabolic process [inference]

negative regulation of phosphorylation [inference]

negative regulation of protein phosphorylation [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein kinase activity by regulation of protein phosphorylation

negative regulation of protein tyrosine kinase activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

negative regulation of protein autophosphorylation

negative regulation of peptidyl-tyrosine phosphorylation

negative regulation of protein tyrosine kinase activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

negative regulation of kinase activity [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein kinase activity by regulation of protein phosphorylation

negative regulation of protein tyrosine kinase activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of interleukin-1 production [inference]

negative regulation of interleukin-1 beta production

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor production

negative regulation of response to stimulus [inference]

negative regulation of signal transduction [inference]

negative regulation of ERBB signaling pathway [inference]

negative regulation of epidermal growth factor receptor signaling pathway

negative regulation of epidermal growth factor-activated receptor activity

negative regulation of intracellular signal transduction [inference]

negative regulation of MAPK cascade [inference]

negative regulation of ERK1 and ERK2 cascade

negative regulation of muscle adaptation [inference]

negative regulation of cardiac muscle adaptation [inference]

negative regulation of cardiac muscle hypertrophy in response to stress

negative regulation of multicellular organismal process [inference]

negative regulation of cytokine production [inference]

negative regulation of interleukin-1 production [inference]

negative regulation of interleukin-1 beta production

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor production

negative regulation of muscle hypertrophy [inference]

negative regulation of cardiac muscle hypertrophy [inference]

negative regulation of cardiac muscle hypertrophy in response to stress

negative regulation of muscle adaptation [inference]

negative regulation of cardiac muscle adaptation [inference]

negative regulation of cardiac muscle hypertrophy in response to stress

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

negative regulation of signal transduction [inference]

negative regulation of ERBB signaling pathway [inference]

negative regulation of epidermal growth factor receptor signaling pathway

negative regulation of epidermal growth factor-activated receptor activity

negative regulation of intracellular signal transduction [inference]

negative regulation of MAPK cascade [inference]

negative regulation of ERK1 and ERK2 cascade

regulation of signaling receptor activity

regulation of epidermal growth factor-activated receptor activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

negative regulation of signaling receptor activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

regulation of ERBB signaling pathway [inference]

regulation of epidermal growth factor receptor signaling pathway [inference]

negative regulation of epidermal growth factor receptor signaling pathway

negative regulation of epidermal growth factor-activated receptor activity

negative regulation of ERBB signaling pathway [inference]

negative regulation of epidermal growth factor receptor signaling pathway

negative regulation of epidermal growth factor-activated receptor activity

regulation of intracellular signal transduction [inference]

regulation of MAPK cascade [inference]

negative regulation of MAPK cascade [inference]

negative regulation of ERK1 and ERK2 cascade

regulation of ERK1 and ERK2 cascade [inference]

negative regulation of ERK1 and ERK2 cascade

negative regulation of intracellular signal transduction [inference]

negative regulation of MAPK cascade [inference]

negative regulation of ERK1 and ERK2 cascade

regulation of muscle adaptation [inference]

regulation of cardiac muscle hypertrophy [inference]

negative regulation of cardiac muscle hypertrophy [inference]

negative regulation of cardiac muscle hypertrophy in response to stress

regulation of cardiac muscle hypertrophy in response to stress [inference]

negative regulation of cardiac muscle hypertrophy in response to stress

regulation of cardiac muscle adaptation [inference]

negative regulation of cardiac muscle adaptation [inference]

negative regulation of cardiac muscle hypertrophy in response to stress

regulation of cardiac muscle hypertrophy in response to stress [inference]

negative regulation of cardiac muscle hypertrophy in response to stress

negative regulation of muscle adaptation [inference]

negative regulation of cardiac muscle adaptation [inference]

negative regulation of cardiac muscle hypertrophy in response to stress

negative regulation of response to stimulus [inference]

negative regulation of signal transduction [inference]

negative regulation of ERBB signaling pathway [inference]

negative regulation of epidermal growth factor receptor signaling pathway

negative regulation of epidermal growth factor-activated receptor activity

negative regulation of intracellular signal transduction [inference]

negative regulation of MAPK cascade [inference]

negative regulation of ERK1 and ERK2 cascade

negative regulation of muscle adaptation [inference]

negative regulation of cardiac muscle adaptation [inference]

negative regulation of cardiac muscle hypertrophy in response to stress

regulation of response to stress [inference]

regulation of cardiac muscle hypertrophy in response to stress [inference]

negative regulation of cardiac muscle hypertrophy in response to stress

regulation of developmental process [inference]

regulation of cell differentiation [inference]

regulation of epithelial cell differentiation [inference]

regulation of epidermal cell differentiation [inference]

regulation of keratinocyte differentiation

regulation of epidermis development [inference]

regulation of epidermal cell differentiation [inference]

regulation of keratinocyte differentiation

regulation of multicellular organismal development [inference]

regulation of epithelial cell differentiation [inference]

regulation of epidermal cell differentiation [inference]

regulation of keratinocyte differentiation

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

enzyme-linked receptor protein signaling pathway [inference]

transmembrane receptor protein tyrosine kinase signaling pathway [inference]

ERBB signaling pathway [inference]

epidermal growth factor receptor signaling pathway

hormone-mediated signaling pathway [inference]

steroid hormone mediated signaling pathway [inference]

intracellular steroid hormone receptor signaling pathway [inference]

progesterone receptor signaling pathway

intracellular receptor signaling pathway [inference]

intracellular steroid hormone receptor signaling pathway [inference]

progesterone receptor signaling pathway

intracellular signal transduction [inference]

regulation of cell communication [inference]

regulation of signal transduction [inference]

negative regulation of signal transduction [inference]

negative regulation of ERBB signaling pathway [inference]

negative regulation of epidermal growth factor receptor signaling pathway

negative regulation of epidermal growth factor-activated receptor activity

negative regulation of intracellular signal transduction [inference]

negative regulation of MAPK cascade [inference]

negative regulation of ERK1 and ERK2 cascade

regulation of signaling receptor activity

regulation of epidermal growth factor-activated receptor activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

negative regulation of signaling receptor activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

regulation of ERBB signaling pathway [inference]

regulation of epidermal growth factor receptor signaling pathway [inference]

negative regulation of epidermal growth factor receptor signaling pathway

negative regulation of epidermal growth factor-activated receptor activity

negative regulation of ERBB signaling pathway [inference]

negative regulation of epidermal growth factor receptor signaling pathway

negative regulation of epidermal growth factor-activated receptor activity

regulation of intracellular signal transduction [inference]

regulation of MAPK cascade [inference]

negative regulation of MAPK cascade [inference]

negative regulation of ERK1 and ERK2 cascade

regulation of ERK1 and ERK2 cascade [inference]

negative regulation of ERK1 and ERK2 cascade

negative regulation of intracellular signal transduction [inference]

negative regulation of MAPK cascade [inference]

negative regulation of ERK1 and ERK2 cascade

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of ERBB signaling pathway [inference]

negative regulation of epidermal growth factor receptor signaling pathway

negative regulation of epidermal growth factor-activated receptor activity

negative regulation of intracellular signal transduction [inference]

negative regulation of MAPK cascade [inference]

negative regulation of ERK1 and ERK2 cascade

regulation of cellular metabolic process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of phosphorus metabolic process [inference]

negative regulation of phosphate metabolic process [inference]

negative regulation of phosphorylation [inference]

negative regulation of protein phosphorylation [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein kinase activity by regulation of protein phosphorylation

negative regulation of protein tyrosine kinase activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

negative regulation of protein autophosphorylation

negative regulation of peptidyl-tyrosine phosphorylation

negative regulation of protein tyrosine kinase activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

negative regulation of kinase activity [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein kinase activity by regulation of protein phosphorylation

negative regulation of protein tyrosine kinase activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of interleukin-1 production [inference]

negative regulation of interleukin-1 beta production

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor production

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

negative regulation of cytokine production [inference]

negative regulation of interleukin-1 production [inference]

negative regulation of interleukin-1 beta production

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor production

regulation of interleukin-1 production [inference]

regulation of interleukin-1 beta production [inference]

negative regulation of interleukin-1 beta production

negative regulation of interleukin-1 production [inference]

negative regulation of interleukin-1 beta production

regulation of tumor necrosis factor superfamily cytokine production [inference]

regulation of tumor necrosis factor production [inference]

negative regulation of tumor necrosis factor production

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor production

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of interleukin-1 production [inference]

negative regulation of interleukin-1 beta production

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor production

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of interleukin-1 production [inference]

negative regulation of interleukin-1 beta production

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor production

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of interleukin-1 production [inference]

negative regulation of interleukin-1 beta production

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor production

regulation of phosphorus metabolic process [inference]

negative regulation of phosphorus metabolic process [inference]

negative regulation of phosphate metabolic process [inference]

negative regulation of phosphorylation [inference]

negative regulation of protein phosphorylation [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein kinase activity by regulation of protein phosphorylation

negative regulation of protein tyrosine kinase activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

negative regulation of protein autophosphorylation

negative regulation of peptidyl-tyrosine phosphorylation

negative regulation of protein tyrosine kinase activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

negative regulation of kinase activity [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein kinase activity by regulation of protein phosphorylation

negative regulation of protein tyrosine kinase activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

regulation of phosphate metabolic process [inference]

regulation of phosphorylation [inference]

regulation of protein phosphorylation [inference]

negative regulation of protein phosphorylation [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein kinase activity by regulation of protein phosphorylation

negative regulation of protein tyrosine kinase activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

negative regulation of protein autophosphorylation

negative regulation of peptidyl-tyrosine phosphorylation

negative regulation of protein tyrosine kinase activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

regulation of protein autophosphorylation [inference]

negative regulation of protein autophosphorylation

regulation of protein kinase activity [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein kinase activity by regulation of protein phosphorylation

negative regulation of protein tyrosine kinase activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

regulation of protein tyrosine kinase activity

regulation of epidermal growth factor-activated receptor activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

negative regulation of protein tyrosine kinase activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

regulation of peptidyl-tyrosine phosphorylation [inference]

negative regulation of peptidyl-tyrosine phosphorylation

negative regulation of protein tyrosine kinase activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

regulation of protein tyrosine kinase activity

regulation of epidermal growth factor-activated receptor activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

negative regulation of protein tyrosine kinase activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

negative regulation of phosphorylation [inference]

negative regulation of protein phosphorylation [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein kinase activity by regulation of protein phosphorylation

negative regulation of protein tyrosine kinase activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

negative regulation of protein autophosphorylation

negative regulation of peptidyl-tyrosine phosphorylation

negative regulation of protein tyrosine kinase activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

negative regulation of kinase activity [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein kinase activity by regulation of protein phosphorylation

negative regulation of protein tyrosine kinase activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

regulation of kinase activity [inference]

negative regulation of kinase activity [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein kinase activity by regulation of protein phosphorylation

negative regulation of protein tyrosine kinase activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

regulation of protein kinase activity [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein kinase activity by regulation of protein phosphorylation

negative regulation of protein tyrosine kinase activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

regulation of protein tyrosine kinase activity

regulation of epidermal growth factor-activated receptor activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

negative regulation of protein tyrosine kinase activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

negative regulation of phosphate metabolic process [inference]

negative regulation of phosphorylation [inference]

negative regulation of protein phosphorylation [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein kinase activity by regulation of protein phosphorylation

negative regulation of protein tyrosine kinase activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

negative regulation of protein autophosphorylation

negative regulation of peptidyl-tyrosine phosphorylation

negative regulation of protein tyrosine kinase activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

negative regulation of kinase activity [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein kinase activity by regulation of protein phosphorylation

negative regulation of protein tyrosine kinase activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

regulation of cell population proliferation [inference]

regulation of epithelial cell proliferation [inference]

regulation of type B pancreatic cell proliferation

regulation of cell differentiation [inference]

regulation of epithelial cell differentiation [inference]

regulation of epidermal cell differentiation [inference]

regulation of keratinocyte differentiation

negative regulation of cellular process [inference]

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of ERBB signaling pathway [inference]

negative regulation of epidermal growth factor receptor signaling pathway

negative regulation of epidermal growth factor-activated receptor activity

negative regulation of intracellular signal transduction [inference]

negative regulation of MAPK cascade [inference]

negative regulation of ERK1 and ERK2 cascade

negative regulation of cellular metabolic process [inference]

negative regulation of phosphorus metabolic process [inference]

negative regulation of phosphate metabolic process [inference]

negative regulation of phosphorylation [inference]

negative regulation of protein phosphorylation [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein kinase activity by regulation of protein phosphorylation

negative regulation of protein tyrosine kinase activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

negative regulation of protein autophosphorylation

negative regulation of peptidyl-tyrosine phosphorylation

negative regulation of protein tyrosine kinase activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

negative regulation of kinase activity [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein kinase activity by regulation of protein phosphorylation

negative regulation of protein tyrosine kinase activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of interleukin-1 production [inference]

negative regulation of interleukin-1 beta production

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor production

regulation of multicellular organismal process [inference]

regulation of cytokine production [inference]

negative regulation of cytokine production [inference]

negative regulation of interleukin-1 production [inference]

negative regulation of interleukin-1 beta production

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor production

regulation of interleukin-1 production [inference]

regulation of interleukin-1 beta production [inference]

negative regulation of interleukin-1 beta production

negative regulation of interleukin-1 production [inference]

negative regulation of interleukin-1 beta production

regulation of tumor necrosis factor superfamily cytokine production [inference]

regulation of tumor necrosis factor production [inference]

negative regulation of tumor necrosis factor production

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor production

regulation of system process [inference]

regulation of muscle system process [inference]

regulation of muscle hypertrophy [inference]

regulation of cardiac muscle hypertrophy [inference]

negative regulation of cardiac muscle hypertrophy [inference]

negative regulation of cardiac muscle hypertrophy in response to stress

regulation of cardiac muscle hypertrophy in response to stress [inference]

negative regulation of cardiac muscle hypertrophy in response to stress

negative regulation of muscle hypertrophy [inference]

negative regulation of cardiac muscle hypertrophy [inference]

negative regulation of cardiac muscle hypertrophy in response to stress

regulation of muscle adaptation [inference]

regulation of cardiac muscle hypertrophy [inference]

negative regulation of cardiac muscle hypertrophy [inference]

negative regulation of cardiac muscle hypertrophy in response to stress

regulation of cardiac muscle hypertrophy in response to stress [inference]

negative regulation of cardiac muscle hypertrophy in response to stress

regulation of cardiac muscle adaptation [inference]

negative regulation of cardiac muscle adaptation [inference]

negative regulation of cardiac muscle hypertrophy in response to stress

regulation of cardiac muscle hypertrophy in response to stress [inference]

negative regulation of cardiac muscle hypertrophy in response to stress

negative regulation of muscle adaptation [inference]

negative regulation of cardiac muscle adaptation [inference]

negative regulation of cardiac muscle hypertrophy in response to stress

negative regulation of multicellular organismal process [inference]

negative regulation of cytokine production [inference]

negative regulation of interleukin-1 production [inference]

negative regulation of interleukin-1 beta production

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor production

negative regulation of muscle hypertrophy [inference]

negative regulation of cardiac muscle hypertrophy [inference]

negative regulation of cardiac muscle hypertrophy in response to stress

negative regulation of muscle adaptation [inference]

negative regulation of cardiac muscle adaptation [inference]

negative regulation of cardiac muscle hypertrophy in response to stress

regulation of multicellular organismal development [inference]

regulation of epithelial cell differentiation [inference]

regulation of epidermal cell differentiation [inference]

regulation of keratinocyte differentiation

regulation of molecular function [inference]

regulation of signaling receptor activity

regulation of epidermal growth factor-activated receptor activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

negative regulation of signaling receptor activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

negative regulation of molecular function [inference]

negative regulation of catalytic activity [inference]

negative regulation of transferase activity [inference]

negative regulation of kinase activity [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein kinase activity by regulation of protein phosphorylation

negative regulation of protein tyrosine kinase activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

negative regulation of signaling receptor activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

regulation of catalytic activity [inference]

negative regulation of catalytic activity [inference]

negative regulation of transferase activity [inference]

negative regulation of kinase activity [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein kinase activity by regulation of protein phosphorylation

negative regulation of protein tyrosine kinase activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

regulation of transferase activity [inference]

regulation of kinase activity [inference]

negative regulation of kinase activity [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein kinase activity by regulation of protein phosphorylation

negative regulation of protein tyrosine kinase activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

regulation of protein kinase activity [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein kinase activity by regulation of protein phosphorylation

negative regulation of protein tyrosine kinase activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

regulation of protein tyrosine kinase activity

regulation of epidermal growth factor-activated receptor activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

negative regulation of protein tyrosine kinase activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

negative regulation of transferase activity [inference]

negative regulation of kinase activity [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein kinase activity by regulation of protein phosphorylation

negative regulation of protein tyrosine kinase activity [inference]

negative regulation of epidermal growth factor-activated receptor activity

regulation of binding [inference]

regulation of protein binding

Displaying **all 4** entries
GO Term	Evidence Code	PMID
nucleus	IEA
cytoplasm	IDA	16648858
cytosol	ISO
plasma membrane	IDA	16648858

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

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GO Term	Evidence Code	PMID
protein binding	IPI	15102471 16247031 20418913 22975324 28925396
SH3 domain binding	ISO
kinase binding	ISO
protein kinase binding	ISO
protein kinase binding	IEA

GO Hierarchy

molecular function

binding [inference]

protein binding

enzyme binding [inference]

kinase binding

protein kinase binding

GTPase binding [inference]

small GTPase binding

protein domain specific binding [inference]

SH3 domain binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

erbb receptor feedback inhibitor 1

Functional Category

E: Amino acid transport and metabolism
G: Carbohydrate transport and metabolism
T: Signal transduction mechanisms

Displaying **all 2** entries
Gene Ontology
negative regulation of epidermal growth factor receptor signaling pathway
regulation of keratinocyte differentiation

Displaying **all 2** entries
InterPro
Cdc42 binding domain-like
Mig-6 domain

Disease

Disease Ontology

Displaying **all 2** entries
DO ID	Disease Name	Source
DOID:1380	endometrial cancer	Alliance of Genome Resources
DOID:8398	osteoarthritis	Alliance of Genome Resources

Ortholog

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Homo sapiens	54206	Xenbase:XB-GENE-1005334	HUMAN47288
Xenopus tropicalis	74155	Xenbase:XB-GENE-1005334
Rattus norvegicus	313729	Xenbase:XB-GENE-1005334	RATNO33489
Pan troglodytes	469787		PANTR19846
Canis lupus familiaris	489636		CANLF15807
Bos taurus	516303		BOVIN08361
Macaca mulatta	722072		MACMU22827
Danio rerio	798009		DANRE03020
Monodelphis domestica	100010313		MONDO21744
Equus caballus	100052062		HORSE28641

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

Search Tools

Guidelines

Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements