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ezrin

Summary

Gene Symbol

Organism

Homo sapiens (human)

External Links

NCBI Gene

7430

KEGG Gene ID

PubChem

7430

Alliance of Genome Resources

HGNC:12691

Annotation

Keyword

3D-structure
Acetylation
Cell membrane
Cell projection
Cell shape
Coiled coil
Cytoskeleton
Direct protein sequencing
Phosphoprotein
Proteomics identification
Reference proteome
S-nitrosylation

Proteins

Displaying 1 entry
UniProt	Protein Name
P15311	Cytovillin Villin-2 p81

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **11 - 15** of 53 in total

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GO Term	Evidence Code	PMID
membrane to membrane docking	IEP
microvillus assembly	IMP
actin cytoskeleton organization	IMP
astral microtubule organization	IMP
protein-containing complex localization	IMP

GO Hierarchy

biological process

cellular process [inference]

microtubule-based process [inference]

microtubule cytoskeleton organization [inference]

spindle organization [inference]

astral microtubule organization

cytoplasmic microtubule organization [inference]

cell adhesion [inference]

cell-cell adhesion [inference]

leukocyte cell-cell adhesion

establishment or maintenance of cell polarity [inference]

establishment of cell polarity [inference]

establishment of monopolar cell polarity [inference]

establishment of apical/basal cell polarity [inference]

establishment of epithelial cell apical/basal polarity

establishment of epithelial cell polarity [inference]

establishment of epithelial cell apical/basal polarity

establishment or maintenance of bipolar cell polarity [inference]

establishment or maintenance of apical/basal cell polarity

establishment of apical/basal cell polarity [inference]

establishment of epithelial cell apical/basal polarity

establishment or maintenance of epithelial cell apical/basal polarity [inference]

establishment of epithelial cell apical/basal polarity

establishment or maintenance of monopolar cell polarity [inference]

establishment of monopolar cell polarity [inference]

establishment of apical/basal cell polarity [inference]

establishment of epithelial cell apical/basal polarity

signal transduction [inference]

G protein-coupled receptor signaling pathway [inference]

sphingosine-1-phosphate receptor signaling pathway

intracellular signal transduction [inference]

intracellular signaling cassette [inference]

cAMP/PKA signal transduction

sphingolipid mediated signaling pathway [inference]

sphingosine-1-phosphate receptor signaling pathway

vesicle-mediated transport [inference]

endocytosis [inference]

receptor-mediated endocytosis [inference]

receptor internalization

cell cycle process [inference]

spindle organization [inference]

astral microtubule organization

membrane docking [inference]

membrane to membrane docking

actin filament-based process [inference]

actin cytoskeleton organization

cortical actin cytoskeleton organization [inference]

terminal web assembly

postsynaptic actin cytoskeleton organization

cellular developmental process [inference]

cell differentiation [inference]

epithelial cell differentiation [inference]

polarized epithelial cell differentiation [inference]

establishment of epithelial cell apical/basal polarity

cell development [inference]

epithelial cell development [inference]

endothelial cell development [inference]

establishment of endothelial barrier

cellular localization [inference]

localization within membrane [inference]

protein localization to membrane [inference]

protein localization to plasma membrane

cellular response to stimulus [inference]

cellular response to chemical stimulus [inference]

cellular response to nitrogen compound [inference]

cellular response to cAMP

cellular response to oxygen-containing compound [inference]

cellular response to cAMP

microtubule organizing center localization [inference]

centrosome localization [inference]

establishment of centrosome localization

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

cytoskeleton organization [inference]

microtubule cytoskeleton organization [inference]

spindle organization [inference]

astral microtubule organization

cytoplasmic microtubule organization [inference]

actin cytoskeleton organization

cortical actin cytoskeleton organization [inference]

terminal web assembly

postsynaptic actin cytoskeleton organization

cortical cytoskeleton organization [inference]

cortical actin cytoskeleton organization [inference]

terminal web assembly

cortical microtubule organization

postsynaptic cytoskeleton organization [inference]

postsynaptic actin cytoskeleton organization

organelle assembly [inference]

membraneless organelle assembly [inference]

terminal web assembly

cellular component assembly [inference]

cell projection assembly [inference]

plasma membrane bounded cell projection assembly [inference]

actin filament bundle assembly

organelle assembly [inference]

membraneless organelle assembly [inference]

terminal web assembly

cell projection organization [inference]

cell projection assembly [inference]

plasma membrane bounded cell projection assembly [inference]

plasma membrane bounded cell projection organization [inference]

microvillus organization [inference]

microvillus assembly

plasma membrane bounded cell projection assembly [inference]

regulation of cellular component size [inference]

regulation of cell projection size [inference]

regulation of microvillus length

supramolecular fiber organization [inference]

actin filament organization [inference]

actin filament bundle organization [inference]

actin filament bundle assembly

cytoplasmic microtubule organization [inference]

multicellular organismal process [inference]

system process [inference]

digestive system process [inference]

intestinal absorption [inference]

intestinal hexose absorption [inference]

intestinal D-glucose absorption

developmental process [inference]

anatomical structure morphogenesis [inference]

animal organ morphogenesis [inference]

gland morphogenesis

anatomical structure development [inference]

cell development [inference]

epithelial cell development [inference]

endothelial cell development [inference]

establishment of endothelial barrier

cellular developmental process [inference]

cell differentiation [inference]

epithelial cell differentiation [inference]

polarized epithelial cell differentiation [inference]

establishment of epithelial cell apical/basal polarity

cell development [inference]

epithelial cell development [inference]

endothelial cell development [inference]

establishment of endothelial barrier

response to stimulus [inference]

response to chemical [inference]

response to organophosphorus [inference]

response to cAMP [inference]

cellular response to cAMP

cellular response to chemical stimulus [inference]

cellular response to nitrogen compound [inference]

cellular response to cAMP

cellular response to oxygen-containing compound [inference]

cellular response to cAMP

response to nitrogen compound [inference]

response to purine-containing compound [inference]

response to cAMP [inference]

cellular response to cAMP

cellular response to nitrogen compound [inference]

cellular response to cAMP

response to oxygen-containing compound [inference]

response to cAMP [inference]

cellular response to cAMP

cellular response to oxygen-containing compound [inference]

cellular response to cAMP

cellular response to stimulus [inference]

cellular response to chemical stimulus [inference]

cellular response to nitrogen compound [inference]

cellular response to cAMP

cellular response to oxygen-containing compound [inference]

cellular response to cAMP

localization [inference]

macromolecule localization [inference]

intracellular protein localization [inference]

protein localization to membrane [inference]

protein localization to plasma membrane

protein localization to cell periphery [inference]

protein-containing complex localization

establishment of localization [inference]

transport [inference]

vesicle-mediated transport [inference]

endocytosis [inference]

receptor-mediated endocytosis [inference]

receptor internalization

import into cell [inference]

endocytosis [inference]

receptor-mediated endocytosis [inference]

receptor internalization

establishment of localization in cell [inference]

establishment of centrosome localization

establishment of organelle localization [inference]

establishment of centrosome localization

organelle localization [inference]

establishment of organelle localization [inference]

establishment of centrosome localization

cellular localization [inference]

localization within membrane [inference]

protein localization to membrane [inference]

protein localization to plasma membrane

microtubule organizing center localization [inference]

centrosome localization [inference]

establishment of centrosome localization

biological regulation [inference]

regulation of biological process [inference]

regulation of immune system process [inference]

negative regulation of immune system process [inference]

negative regulation of antigen receptor-mediated signaling pathway [inference]

negative regulation of T cell receptor signaling pathway

regulation of immune response [inference]

regulation of antigen receptor-mediated signaling pathway [inference]

regulation of T cell receptor signaling pathway [inference]

negative regulation of T cell receptor signaling pathway

negative regulation of antigen receptor-mediated signaling pathway [inference]

negative regulation of T cell receptor signaling pathway

regulation of signaling [inference]

regulation of signal transduction [inference]

regulation of cytokine-mediated signaling pathway [inference]

positive regulation of cytokine-mediated signaling pathway [inference]

positive regulation of interleukin-2-mediated signaling pathway

regulation of interleukin-2-mediated signaling pathway [inference]

positive regulation of interleukin-2-mediated signaling pathway

positive regulation of signal transduction [inference]

positive regulation of cytokine-mediated signaling pathway [inference]

positive regulation of interleukin-2-mediated signaling pathway

negative regulation of signal transduction [inference]

negative regulation of antigen receptor-mediated signaling pathway [inference]

negative regulation of T cell receptor signaling pathway

negative regulation of intracellular signal transduction [inference]

negative regulation of MAPK cascade [inference]

regulation of antigen receptor-mediated signaling pathway [inference]

regulation of T cell receptor signaling pathway [inference]

negative regulation of T cell receptor signaling pathway

negative regulation of antigen receptor-mediated signaling pathway [inference]

negative regulation of T cell receptor signaling pathway

regulation of intracellular signal transduction [inference]

regulation of MAPK cascade [inference]

negative regulation of MAPK cascade [inference]

regulation of ERK1 and ERK2 cascade [inference]

negative regulation of ERK1 and ERK2 cascade

regulation of p38MAPK cascade [inference]

negative regulation of p38MAPK cascade

regulation of non-canonical NF-kappaB signal transduction

negative regulation of intracellular signal transduction [inference]

negative regulation of MAPK cascade [inference]

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of cytokine-mediated signaling pathway [inference]

positive regulation of interleukin-2-mediated signaling pathway

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of antigen receptor-mediated signaling pathway [inference]

negative regulation of T cell receptor signaling pathway

negative regulation of intracellular signal transduction [inference]

negative regulation of MAPK cascade [inference]

regulation of localization [inference]

regulation of protein localization [inference]

positive regulation of protein localization [inference]

positive regulation of protein localization to cell periphery [inference]

positive regulation of protein localization to plasma membrane

positive regulation of protein localization to membrane [inference]

positive regulation of protein localization to plasma membrane

positive regulation of protein localization to endosome [inference]

positive regulation of protein localization to early endosome

regulation of protein localization to cell periphery [inference]

regulation of protein localization to plasma membrane [inference]

positive regulation of protein localization to plasma membrane

positive regulation of protein localization to cell periphery [inference]

positive regulation of protein localization to plasma membrane

regulation of protein localization to membrane [inference]

regulation of protein localization to plasma membrane [inference]

positive regulation of protein localization to plasma membrane

positive regulation of protein localization to membrane [inference]

positive regulation of protein localization to plasma membrane

regulation of protein localization to endosome [inference]

regulation of protein localization to early endosome [inference]

positive regulation of protein localization to early endosome

positive regulation of protein localization to endosome [inference]

positive regulation of protein localization to early endosome

regulation of transport [inference]

regulation of intracellular transport [inference]

positive regulation of intracellular transport [inference]

positive regulation of early endosome to late endosome transport

regulation of early endosome to late endosome transport [inference]

positive regulation of early endosome to late endosome transport

positive regulation of transport [inference]

positive regulation of intracellular transport [inference]

positive regulation of early endosome to late endosome transport

regulation of vesicle-mediated transport [inference]

regulation of early endosome to late endosome transport [inference]

positive regulation of early endosome to late endosome transport

regulation of cellular localization [inference]

regulation of intracellular transport [inference]

positive regulation of intracellular transport [inference]

positive regulation of early endosome to late endosome transport

regulation of early endosome to late endosome transport [inference]

positive regulation of early endosome to late endosome transport

regulation of protein localization to membrane [inference]

regulation of protein localization to plasma membrane [inference]

positive regulation of protein localization to plasma membrane

positive regulation of protein localization to membrane [inference]

positive regulation of protein localization to plasma membrane

regulation of growth [inference]

positive regulation of growth [inference]

positive regulation of developmental growth [inference]

positive regulation of multicellular organism growth

regulation of developmental growth [inference]

regulation of multicellular organism growth [inference]

positive regulation of multicellular organism growth

positive regulation of developmental growth [inference]

positive regulation of multicellular organism growth

positive regulation of biological process [inference]

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of cytokine-mediated signaling pathway [inference]

positive regulation of interleukin-2-mediated signaling pathway

positive regulation of growth [inference]

positive regulation of developmental growth [inference]

positive regulation of multicellular organism growth

positive regulation of cellular process [inference]

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of catabolic process [inference]

positive regulation of protein catabolic process

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of protein metabolic process [inference]

positive regulation of protein catabolic process

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of cytokine-mediated signaling pathway [inference]

positive regulation of interleukin-2-mediated signaling pathway

positive regulation of intracellular transport [inference]

positive regulation of early endosome to late endosome transport

positive regulation of protein localization to membrane [inference]

positive regulation of protein localization to plasma membrane

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of cytokine-mediated signaling pathway [inference]

positive regulation of interleukin-2-mediated signaling pathway

positive regulation of response to cytokine stimulus [inference]

positive regulation of cytokine-mediated signaling pathway [inference]

positive regulation of interleukin-2-mediated signaling pathway

positive regulation of transport [inference]

positive regulation of intracellular transport [inference]

positive regulation of early endosome to late endosome transport

positive regulation of developmental process [inference]

positive regulation of developmental growth [inference]

positive regulation of multicellular organism growth

positive regulation of multicellular organismal process [inference]

positive regulation of multicellular organism growth

positive regulation of protein localization [inference]

positive regulation of protein localization to cell periphery [inference]

positive regulation of protein localization to plasma membrane

positive regulation of protein localization to membrane [inference]

positive regulation of protein localization to plasma membrane

positive regulation of protein localization to endosome [inference]

positive regulation of protein localization to early endosome

negative regulation of biological process [inference]

negative regulation of immune system process [inference]

negative regulation of antigen receptor-mediated signaling pathway [inference]

negative regulation of T cell receptor signaling pathway

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of antigen receptor-mediated signaling pathway [inference]

negative regulation of T cell receptor signaling pathway

negative regulation of intracellular signal transduction [inference]

negative regulation of MAPK cascade [inference]

negative regulation of cellular process [inference]

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of interleukin-2 production

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of interleukin-2 production

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of antigen receptor-mediated signaling pathway [inference]

negative regulation of T cell receptor signaling pathway

negative regulation of intracellular signal transduction [inference]

negative regulation of MAPK cascade [inference]

negative regulation of response to stimulus [inference]

negative regulation of signal transduction [inference]

negative regulation of antigen receptor-mediated signaling pathway [inference]

negative regulation of T cell receptor signaling pathway

negative regulation of intracellular signal transduction [inference]

negative regulation of MAPK cascade [inference]

negative regulation of multicellular organismal process [inference]

negative regulation of cytokine production [inference]

negative regulation of interleukin-2 production

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

regulation of cytokine-mediated signaling pathway [inference]

positive regulation of cytokine-mediated signaling pathway [inference]

positive regulation of interleukin-2-mediated signaling pathway

regulation of interleukin-2-mediated signaling pathway [inference]

positive regulation of interleukin-2-mediated signaling pathway

positive regulation of signal transduction [inference]

positive regulation of cytokine-mediated signaling pathway [inference]

positive regulation of interleukin-2-mediated signaling pathway

negative regulation of signal transduction [inference]

negative regulation of antigen receptor-mediated signaling pathway [inference]

negative regulation of T cell receptor signaling pathway

negative regulation of intracellular signal transduction [inference]

negative regulation of MAPK cascade [inference]

regulation of antigen receptor-mediated signaling pathway [inference]

regulation of T cell receptor signaling pathway [inference]

negative regulation of T cell receptor signaling pathway

negative regulation of antigen receptor-mediated signaling pathway [inference]

negative regulation of T cell receptor signaling pathway

regulation of intracellular signal transduction [inference]

regulation of MAPK cascade [inference]

negative regulation of MAPK cascade [inference]

regulation of ERK1 and ERK2 cascade [inference]

negative regulation of ERK1 and ERK2 cascade

regulation of p38MAPK cascade [inference]

negative regulation of p38MAPK cascade

regulation of non-canonical NF-kappaB signal transduction

negative regulation of intracellular signal transduction [inference]

negative regulation of MAPK cascade [inference]

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of cytokine-mediated signaling pathway [inference]

positive regulation of interleukin-2-mediated signaling pathway

positive regulation of response to cytokine stimulus [inference]

positive regulation of cytokine-mediated signaling pathway [inference]

positive regulation of interleukin-2-mediated signaling pathway

negative regulation of response to stimulus [inference]

negative regulation of signal transduction [inference]

negative regulation of antigen receptor-mediated signaling pathway [inference]

negative regulation of T cell receptor signaling pathway

negative regulation of intracellular signal transduction [inference]

negative regulation of MAPK cascade [inference]

regulation of immune response [inference]

regulation of antigen receptor-mediated signaling pathway [inference]

regulation of T cell receptor signaling pathway [inference]

negative regulation of T cell receptor signaling pathway

negative regulation of antigen receptor-mediated signaling pathway [inference]

negative regulation of T cell receptor signaling pathway

regulation of response to cytokine stimulus [inference]

regulation of cytokine-mediated signaling pathway [inference]

positive regulation of cytokine-mediated signaling pathway [inference]

positive regulation of interleukin-2-mediated signaling pathway

regulation of interleukin-2-mediated signaling pathway [inference]

positive regulation of interleukin-2-mediated signaling pathway

positive regulation of response to cytokine stimulus [inference]

positive regulation of cytokine-mediated signaling pathway [inference]

positive regulation of interleukin-2-mediated signaling pathway

regulation of developmental process [inference]

regulation of anatomical structure morphogenesis [inference]

regulation of cell morphogenesis [inference]

regulation of cell shape

regulation of developmental growth [inference]

regulation of multicellular organism growth [inference]

positive regulation of multicellular organism growth

positive regulation of developmental growth [inference]

positive regulation of multicellular organism growth

positive regulation of developmental process [inference]

positive regulation of developmental growth [inference]

positive regulation of multicellular organism growth

regulation of cellular process [inference]

signal transduction [inference]

G protein-coupled receptor signaling pathway [inference]

sphingosine-1-phosphate receptor signaling pathway

intracellular signal transduction [inference]

intracellular signaling cassette [inference]

cAMP/PKA signal transduction

sphingolipid mediated signaling pathway [inference]

sphingosine-1-phosphate receptor signaling pathway

regulation of cell communication [inference]

regulation of signal transduction [inference]

regulation of cytokine-mediated signaling pathway [inference]

positive regulation of cytokine-mediated signaling pathway [inference]

positive regulation of interleukin-2-mediated signaling pathway

regulation of interleukin-2-mediated signaling pathway [inference]

positive regulation of interleukin-2-mediated signaling pathway

positive regulation of signal transduction [inference]

positive regulation of cytokine-mediated signaling pathway [inference]

positive regulation of interleukin-2-mediated signaling pathway

negative regulation of signal transduction [inference]

negative regulation of antigen receptor-mediated signaling pathway [inference]

negative regulation of T cell receptor signaling pathway

negative regulation of intracellular signal transduction [inference]

negative regulation of MAPK cascade [inference]

regulation of antigen receptor-mediated signaling pathway [inference]

regulation of T cell receptor signaling pathway [inference]

negative regulation of T cell receptor signaling pathway

negative regulation of antigen receptor-mediated signaling pathway [inference]

negative regulation of T cell receptor signaling pathway

regulation of intracellular signal transduction [inference]

regulation of MAPK cascade [inference]

negative regulation of MAPK cascade [inference]

regulation of ERK1 and ERK2 cascade [inference]

negative regulation of ERK1 and ERK2 cascade

regulation of p38MAPK cascade [inference]

negative regulation of p38MAPK cascade

regulation of non-canonical NF-kappaB signal transduction

negative regulation of intracellular signal transduction [inference]

negative regulation of MAPK cascade [inference]

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of cytokine-mediated signaling pathway [inference]

positive regulation of interleukin-2-mediated signaling pathway

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of antigen receptor-mediated signaling pathway [inference]

negative regulation of T cell receptor signaling pathway

negative regulation of intracellular signal transduction [inference]

negative regulation of MAPK cascade [inference]

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of interleukin-2 production

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

positive regulation of biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

negative regulation of cytokine production [inference]

negative regulation of interleukin-2 production

regulation of interleukin-2 production [inference]

negative regulation of interleukin-2 production

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

positive regulation of gene expression

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of interleukin-2 production

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of interleukin-2 production

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of interleukin-2 production

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of interleukin-2 production

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of catabolic process [inference]

positive regulation of protein catabolic process

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of protein metabolic process [inference]

positive regulation of protein catabolic process

regulation of catabolic process [inference]

positive regulation of catabolic process [inference]

positive regulation of protein catabolic process

regulation of protein catabolic process [inference]

positive regulation of protein catabolic process

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

negative regulation of cytokine production [inference]

negative regulation of interleukin-2 production

regulation of interleukin-2 production [inference]

negative regulation of interleukin-2 production

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

positive regulation of gene expression

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of interleukin-2 production

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of interleukin-2 production

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of protein metabolic process [inference]

positive regulation of protein catabolic process

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of interleukin-2 production

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

regulation of protein metabolic process [inference]

regulation of protein catabolic process [inference]

positive regulation of protein catabolic process

positive regulation of protein metabolic process [inference]

positive regulation of protein catabolic process

regulation of RNA metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

regulation of primary metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

regulation of RNA metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

regulation of protein metabolic process [inference]

regulation of protein catabolic process [inference]

positive regulation of protein catabolic process

positive regulation of protein metabolic process [inference]

positive regulation of protein catabolic process

regulation of actin filament-based process [inference]

regulation of actin cytoskeleton organization

regulation of cellular component biogenesis [inference]

regulation of organelle assembly

positive regulation of cellular process [inference]

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of catabolic process [inference]

positive regulation of protein catabolic process

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of protein metabolic process [inference]

positive regulation of protein catabolic process

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of cytokine-mediated signaling pathway [inference]

positive regulation of interleukin-2-mediated signaling pathway

positive regulation of intracellular transport [inference]

positive regulation of early endosome to late endosome transport

positive regulation of protein localization to membrane [inference]

positive regulation of protein localization to plasma membrane

negative regulation of cellular process [inference]

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of interleukin-2 production

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of interleukin-2 production

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of antigen receptor-mediated signaling pathway [inference]

negative regulation of T cell receptor signaling pathway

negative regulation of intracellular signal transduction [inference]

negative regulation of MAPK cascade [inference]

regulation of cellular component organization [inference]

regulation of cell projection organization [inference]

regulation of plasma membrane bounded cell projection organization [inference]

regulation of microvillus organization [inference]

regulation of microvillus length

regulation of organelle organization [inference]

regulation of cytoskeleton organization [inference]

regulation of actin cytoskeleton organization

regulation of organelle assembly

regulation of cellular localization [inference]

regulation of intracellular transport [inference]

positive regulation of intracellular transport [inference]

positive regulation of early endosome to late endosome transport

regulation of early endosome to late endosome transport [inference]

positive regulation of early endosome to late endosome transport

regulation of protein localization to membrane [inference]

regulation of protein localization to plasma membrane [inference]

positive regulation of protein localization to plasma membrane

positive regulation of protein localization to membrane [inference]

positive regulation of protein localization to plasma membrane

regulation of vesicle-mediated transport [inference]

regulation of early endosome to late endosome transport [inference]

positive regulation of early endosome to late endosome transport

regulation of multicellular organismal process [inference]

regulation of cytokine production [inference]

negative regulation of cytokine production [inference]

negative regulation of interleukin-2 production

regulation of interleukin-2 production [inference]

negative regulation of interleukin-2 production

regulation of multicellular organism growth [inference]

positive regulation of multicellular organism growth

positive regulation of multicellular organismal process [inference]

positive regulation of multicellular organism growth

negative regulation of multicellular organismal process [inference]

negative regulation of cytokine production [inference]

negative regulation of interleukin-2 production

regulation of biological quality [inference]

regulation of cell shape

regulation of anatomical structure size [inference]

regulation of cellular component size [inference]

regulation of cell projection size [inference]

regulation of microvillus length

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GO Term	Evidence Code	PMID
fibrillar center
ruffle	IDA
immunological synapse	IDA
uropod	IEA
extracellular region	HDA

GO Hierarchy

cellular component

protein-containing complex

cellular anatomical structure [inference]

cytoplasm

cell cortex

microtubule organizing center [inference]

ciliary basal body

cytosol

membrane

plasma membrane

plasma membrane region [inference]

cell projection membrane [inference]

plasma membrane raft

membrane microdomain [inference]

membrane raft [inference]

plasma membrane raft

cell junction [inference]

anchoring junction [inference]

cell-cell junction [inference]

adherens junction

cell-substrate junction [inference]

focal adhesion

leading edge membrane [inference]

ruffle membrane

cell projection

plasma membrane bounded cell projection [inference]

actin-based cell projection [inference]

organelle [inference]

membrane-bounded organelle [inference]

vesicle

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome

extracellular vesicle [inference]

extracellular exosome

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

membraneless organelle [inference]

intracellular membraneless organelle [inference]

cytoskeleton

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome

intracellular membraneless organelle [inference]

cytoskeleton

extracellular organelle [inference]

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

cluster of actin-based cell projections [inference]

brush border

supramolecular complex [inference]

supramolecular polymer [inference]

supramolecular fiber [inference]

polymeric cytoskeletal fiber [inference]

actin filament

Displaying entries **1 - 5** of 19 in total

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GO Term	Evidence Code	PMID
RNA binding	HDA
actin binding	IDA
actin binding	IBA
actin binding	IEA
protein binding	IPI

GO Hierarchy

molecular function

binding [inference]

nucleic acid binding [inference]

RNA binding

protein binding

cytoskeletal protein binding

actin binding

actin filament binding

tubulin binding [inference]

microtubule binding

enzyme binding [inference]

kinase binding [inference]

protein kinase binding [inference]

protein kinase A catalytic subunit binding

ATPase binding

protein domain specific binding

disordered domain specific binding

cell adhesion molecule binding

cadherin binding

protein kinase A binding

protein-containing complex binding [inference]

actin filament binding

Gene Ontology information from NCBI Gene and UniProt.

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

Search Tools

Guidelines

Summary

External Links

Annotation

International Collaboration

Acknowledgements