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vasoactive intestinal peptide receptor 1

Summary

Gene Symbol

VIPR1

Organism

Homo sapiens (human)

External Links

NCBI Gene

7433

PubChem

7433

Alliance of Genome Resources

HGNC:12694

Annotation

Keyword

3D-structure
Alternative splicing
Cell membrane
Disulfide bond
G-protein coupled receptor
Glycoprotein
Reference proteome
Signal
Transmembrane helix

Proteins

Displaying **all 2** entries
UniProt	Protein Name
P32241	Pituitary adenylate cyclase-activating polypeptide type II receptor VPAC1
B4DNY6

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 5** entries
GO Term	Evidence Code	PMID
positive regulation of cell population proliferation	TAS	8389448
cell surface receptor signaling pathway	IEA
G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger	IDA	8390245
G protein-coupled receptor signaling pathway	TAS	8179610
adenylate cyclase-modulating G protein-coupled receptor signaling pathway	IBA

GO Hierarchy

biological process

cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway

G protein-coupled receptor signaling pathway

biological regulation [inference]

regulation of biological process [inference]

positive regulation of biological process [inference]

positive regulation of cellular process [inference]

positive regulation of cell population proliferation

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway

G protein-coupled receptor signaling pathway

regulation of cell population proliferation [inference]

positive regulation of cell population proliferation

positive regulation of cellular process [inference]

positive regulation of cell population proliferation

Displaying **all 2** entries
GO Term	Evidence Code	PMID
receptor complex	IDA	23382219
plasma membrane	IBA TAS

GO Hierarchy

cellular component

protein-containing complex [inference]

receptor complex

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

Displaying **all 4** entries
GO Term	Evidence Code	PMID
protein binding	IPI	23597562 32296183
peptide hormone binding	IBA IPI	8390245
G protein-coupled peptide receptor activity	IBA
vasoactive intestinal polypeptide receptor activity	IBA IDA	8390245

GO Hierarchy

molecular function

binding [inference]

protein binding

amide binding [inference]

peptide binding [inference]

peptide hormone binding

hormone binding [inference]

peptide hormone binding

molecular transducer activity [inference]

signaling receptor activity [inference]

peptide receptor activity [inference]

G protein-coupled peptide receptor activity

transmembrane signaling receptor activity [inference]

G protein-coupled receptor activity [inference]

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

growth hormone releasing hormone receptor a

Functional Category

I: Lipid transport and metabolism
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 4** entries
Gene Ontology
G protein-coupled peptide receptor activity
adenylate cyclase-modulating G protein-coupled receptor signaling pathway
cell surface receptor signaling pathway
peptide hormone binding

Displaying **all 5** entries
InterPro
GPCR family 2, extracellular hormone receptor domain superfamily
GPCR, family 2, extracellular hormone receptor domain
GPCR, family 2, secretin-like, conserved site
GPCR, family 2, secretin-like
GPCR, family 2-like, 7TM

Disease

Disease Ontology

Displaying **all 4** entries
DO ID	Disease Name	Source
DOID:1574	alcohol use disorder	Alliance of Genome Resources
DOID:8577	ulcerative colitis	Alliance of Genome Resources
DOID:8778	Crohn's disease	Alliance of Genome Resources
DOID:9164	achalasia	Alliance of Genome Resources

Ortholog

Displaying entries **31 - 40** of 84 in total

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Species	Gene ID	OrthoDB	Orthologous MAtrix
Gorilla gorilla gorilla	101144054	9595_0:001143	GORGO29197
Oryzias latipes	101155153		ORYLA09144
Oryzias latipes	101161752		ORYLA06720
Tursiops truncatus	101325388		TURTR07711
Octodon degus	101566218		OCTDE19479
Jaculus jaculus	101617034		JACJA13723
Mustela putorius furo	101670012		MUSPF12705
Ficedula albicollis	101814141		FICAL10850
Melopsittacus undulatus	101872303		MELUD04985
Ictidomys tridecemlineatus	101956993		ICTTR13679

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Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements