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WAS/WASL interacting protein family member 1

Summary

Gene Symbol

WIPF1

Organism

Homo sapiens (human)

External Links

NCBI Gene

7456

PubChem

7456

Alliance of Genome Resources

HGNC:12736

Annotation

Keyword

3D-structure
Actin-binding
Alternative splicing
Cell projection
Cytoplasmic vesicle
Cytoskeleton
Methylation
Phosphoprotein
Proteomics identification
Reference proteome
Repeat

Proteins

Displaying **all 4** entries
UniProt	Protein Name
A0A140VJZ9	Wiskott-Aldrich syndrome protein-interacting protein
O43516	Protein PRPL-2 Wiskott-Aldrich syndrome protein-interacting protein
Q2YDC4
E9PB87

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 5** entries
GO Term	Evidence Code	PMID
protein folding	IEA
actin polymerization or depolymerization	TAS	9405671
actin filament-based movement	IBA
response to other organism	IEA
protein-containing complex assembly	TAS	9405671

GO Hierarchy

biological process

cellular process [inference]

protein folding

actin filament-based process [inference]

actin filament-based movement

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cellular component assembly [inference]

protein-containing complex assembly

protein-containing complex organization [inference]

protein-containing complex assembly

supramolecular fiber organization [inference]

actin filament organization [inference]

actin polymerization or depolymerization

biological process involved in interspecies interaction between organisms [inference]

response to other organism

response to stimulus [inference]

response to external stimulus [inference]

response to external biotic stimulus [inference]

response to other organism

response to biotic stimulus [inference]

response to external biotic stimulus [inference]

response to other organism

Displaying **all 5** entries
GO Term	Evidence Code	PMID
ruffle	IEA
cytosol	TAS
actin filament	IBA
actin cytoskeleton	TAS	9405671
cytoplasmic vesicle	IEA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

cytosol

cell projection [inference]

plasma membrane bounded cell projection [inference]

ruffle

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle

non-membrane-bounded organelle [inference]

intracellular non-membrane-bounded organelle [inference]

cytoskeleton [inference]

actin cytoskeleton

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle

intracellular non-membrane-bounded organelle [inference]

cytoskeleton [inference]

actin cytoskeleton

supramolecular complex [inference]

supramolecular polymer [inference]

supramolecular fiber [inference]

polymeric cytoskeletal fiber [inference]

actin filament

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
actin binding	IEA
protein binding	IPI	10202051 11331876 12029088 12591280 12620186 16488394 16582881 17213309 17606906 19805221 19817875 20936779 21398607 21516116 21706016 21988832 23414517 25416956 28514442 29892012 32296183 33961781 35271311 36935496 9405671
profilin binding	TAS	9405671
cytoskeletal anchor activity	IDA	17141616
SH3 domain binding	IPI	19798448

GO Hierarchy

molecular function

binding [inference]

protein binding

profilin binding

cytoskeletal protein binding [inference]

actin binding

protein domain specific binding [inference]

SH3 domain binding

protein folding chaperone

molecular adaptor activity [inference]

protein-macromolecule adaptor activity [inference]

cytoskeletal anchor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

WAS/WASL-interacting protein family member 1

Functional Category

G: Carbohydrate transport and metabolism
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying 1 entry
Gene Ontology
actin binding

Displaying **all 2** entries
InterPro
PH-like domain superfamily
WH2 domain

Ortholog

Displaying entries **1 - 10** of 64 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Xenopus tropicalis	7456	Xenbase:XB-GENE-960803
Xenopus tropicalis	37521	Xenbase:XB-GENE-960803
Saccharomyces cerevisiae S288C	68524	SGD:S000004329
Rattus norvegicus	117538		RATNO28604
Saccharomyces cerevisiae S288C	147179	SGD:S000004329
Mus musculus	215280		MOUSE32837
Pan troglodytes	459755		PANTR29176
Canis lupus familiaris	488409		CANLF13980
Bos taurus	540304		BOVIN24039
Drosophila melanogaster	644150	FB:FBgn0243516