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Guidelines

MIRAGE

Wnt family member 3

Summary

Gene Symbol

WNT3

Organism

Homo sapiens (human)

External Links

NCBI Gene

7473

PubChem

7473

Alliance of Genome Resources

HGNC:12782

Annotation

Keyword

3D-structure
Developmental protein
Disulfide bond
Extracellular matrix
Glycoprotein
Lipoprotein
Proto-oncogene
Reference proteome
Signal
Wnt signaling pathway

Proteins

Displaying 1 entry
UniProt	Protein Name
P56703	Proto-oncogene Int-4 homolog

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 30 in total

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GO Term	Evidence Code	PMID
cell morphogenesis	IMP	15588944
mesoderm formation	IEA
gamete generation	IEA
axon guidance	IEA
anterior/posterior axis specification	IEA

GO Hierarchy

biological process

metabolic process [inference]

biosynthetic process [inference]

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

gene expression

organic substance biosynthetic process [inference]

macromolecule biosynthetic process [inference]

gene expression

cellular metabolic process [inference]

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

gene expression

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

macromolecule biosynthetic process [inference]

gene expression

organic substance biosynthetic process [inference]

macromolecule biosynthetic process [inference]

gene expression

cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

Wnt signaling pathway [inference]

canonical Wnt signaling pathway

cell population proliferation [inference]

stem cell proliferation

cellular metabolic process [inference]

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

gene expression

cellular developmental process [inference]

cell differentiation [inference]

neuron differentiation

dopaminergic neuron differentiation [inference]

midbrain dopaminergic neuron differentiation

cell fate commitment

cellular response to stimulus [inference]

cellular response to chemical stimulus [inference]

cellular response to organic substance [inference]

cellular response to lipid [inference]

cellular response to retinoic acid

cellular response to oxygen-containing compound [inference]

cellular response to retinoic acid

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cell projection organization [inference]

plasma membrane bounded cell projection organization [inference]

neuron projection development [inference]

neuron projection guidance [inference]

axon guidance

reproductive process [inference]

multicellular organismal reproductive process [inference]

gamete generation

multicellular organismal process [inference]

pattern specification process [inference]

axis specification [inference]

developmental process [inference]

anatomical structure morphogenesis [inference]

cell morphogenesis

appendage morphogenesis [inference]

limb morphogenesis [inference]

embryonic limb morphogenesis [inference]

forelimb morphogenesis [inference]

embryonic forelimb morphogenesis

hindlimb morphogenesis [inference]

embryonic hindlimb morphogenesis

embryonic appendage morphogenesis [inference]

embryonic limb morphogenesis [inference]

embryonic morphogenesis [inference]

embryonic appendage morphogenesis [inference]

embryonic limb morphogenesis [inference]

head morphogenesis

anatomical structure formation involved in morphogenesis [inference]

formation of primary germ layer [inference]

mesoderm formation

Spemann organizer formation [inference]

Spemann organizer formation at the anterior end of the primitive streak

limb bud formation

anatomical structure development [inference]

tissue development [inference]

epithelium development [inference]

mammary gland epithelium development

cellular developmental process [inference]

cell differentiation [inference]

neuron differentiation

dopaminergic neuron differentiation [inference]

midbrain dopaminergic neuron differentiation

cell fate commitment

response to stimulus [inference]

response to chemical [inference]

response to organic substance [inference]

response to lipid [inference]

response to retinoic acid [inference]

cellular response to retinoic acid

cellular response to lipid [inference]

cellular response to retinoic acid

cellular response to organic substance [inference]

cellular response to lipid [inference]

cellular response to retinoic acid

cellular response to chemical stimulus [inference]

cellular response to organic substance [inference]

cellular response to lipid [inference]

cellular response to retinoic acid

cellular response to oxygen-containing compound [inference]

cellular response to retinoic acid

response to oxygen-containing compound [inference]

response to retinoic acid [inference]

cellular response to retinoic acid

cellular response to oxygen-containing compound [inference]

cellular response to retinoic acid

cellular response to stimulus [inference]

cellular response to chemical stimulus [inference]

cellular response to organic substance [inference]

cellular response to lipid [inference]

cellular response to retinoic acid

cellular response to oxygen-containing compound [inference]

cellular response to retinoic acid

biological regulation [inference]

regulation of biological process [inference]

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

positive regulation of gene expression

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

regulation of cellular metabolic process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

positive regulation of gene expression

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

positive regulation of gene expression

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

regulation of signaling [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of Wnt signaling pathway

regulation of Wnt signaling pathway [inference]

positive regulation of Wnt signaling pathway

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of Wnt signaling pathway

regulation of growth [inference]

regulation of cell growth [inference]

positive regulation of cell growth [inference]

positive regulation of collateral sprouting [inference]

positive regulation of collateral sprouting in absence of injury

negative regulation of cell growth [inference]

negative regulation of axon extension [inference]

negative regulation of axon extension involved in axon guidance

regulation of extent of cell growth [inference]

regulation of axon extension [inference]

negative regulation of axon extension [inference]

negative regulation of axon extension involved in axon guidance

regulation of axon extension involved in axon guidance [inference]

negative regulation of axon extension involved in axon guidance

regulation of collateral sprouting [inference]

positive regulation of collateral sprouting [inference]

positive regulation of collateral sprouting in absence of injury

regulation of collateral sprouting in absence of injury [inference]

positive regulation of collateral sprouting in absence of injury

negative regulation of growth [inference]

negative regulation of cell growth [inference]

negative regulation of axon extension [inference]

negative regulation of axon extension involved in axon guidance

negative regulation of developmental growth [inference]

negative regulation of axon extension [inference]

negative regulation of axon extension involved in axon guidance

positive regulation of growth [inference]

positive regulation of cell growth [inference]

positive regulation of collateral sprouting [inference]

positive regulation of collateral sprouting in absence of injury

positive regulation of developmental growth [inference]

positive regulation of collateral sprouting [inference]

positive regulation of collateral sprouting in absence of injury

regulation of developmental growth [inference]

regulation of axon extension [inference]

negative regulation of axon extension [inference]

negative regulation of axon extension involved in axon guidance

regulation of axon extension involved in axon guidance [inference]

negative regulation of axon extension involved in axon guidance

positive regulation of developmental growth [inference]

positive regulation of collateral sprouting [inference]

positive regulation of collateral sprouting in absence of injury

negative regulation of developmental growth [inference]

negative regulation of axon extension [inference]

negative regulation of axon extension involved in axon guidance

regulation of collateral sprouting [inference]

positive regulation of collateral sprouting [inference]

positive regulation of collateral sprouting in absence of injury

regulation of collateral sprouting in absence of injury [inference]

positive regulation of collateral sprouting in absence of injury

regulation of locomotion [inference]

negative regulation of locomotion [inference]

negative regulation of chemotaxis [inference]

negative regulation of axon extension involved in axon guidance

regulation of chemotaxis [inference]

negative regulation of chemotaxis [inference]

negative regulation of axon extension involved in axon guidance

positive regulation of biological process [inference]

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of Wnt signaling pathway

positive regulation of growth [inference]

positive regulation of cell growth [inference]

positive regulation of collateral sprouting [inference]

positive regulation of collateral sprouting in absence of injury

positive regulation of developmental growth [inference]

positive regulation of collateral sprouting [inference]

positive regulation of collateral sprouting in absence of injury

positive regulation of cellular process [inference]

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of Wnt signaling pathway

positive regulation of cell growth [inference]

positive regulation of collateral sprouting [inference]

positive regulation of collateral sprouting in absence of injury

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of cell differentiation [inference]

positive regulation of cell development [inference]

positive regulation of neurogenesis [inference]

positive regulation of axonogenesis [inference]

positive regulation of collateral sprouting [inference]

positive regulation of collateral sprouting in absence of injury

positive regulation of osteoblast differentiation

positive regulation of cellular component organization [inference]

positive regulation of cell projection organization [inference]

positive regulation of axonogenesis [inference]

positive regulation of collateral sprouting [inference]

positive regulation of collateral sprouting in absence of injury

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of Wnt signaling pathway

positive regulation of developmental process [inference]

positive regulation of cell differentiation [inference]

positive regulation of cell development [inference]

positive regulation of neurogenesis [inference]

positive regulation of axonogenesis [inference]

positive regulation of collateral sprouting [inference]

positive regulation of collateral sprouting in absence of injury

positive regulation of osteoblast differentiation

positive regulation of developmental growth [inference]

positive regulation of collateral sprouting [inference]

positive regulation of collateral sprouting in absence of injury

positive regulation of nervous system development [inference]

positive regulation of neurogenesis [inference]

positive regulation of axonogenesis [inference]

positive regulation of collateral sprouting [inference]

positive regulation of collateral sprouting in absence of injury

positive regulation of multicellular organismal process [inference]

positive regulation of nervous system development [inference]

positive regulation of neurogenesis [inference]

positive regulation of axonogenesis [inference]

positive regulation of collateral sprouting [inference]

positive regulation of collateral sprouting in absence of injury

negative regulation of biological process [inference]

negative regulation of locomotion [inference]

negative regulation of chemotaxis [inference]

negative regulation of axon extension involved in axon guidance

negative regulation of growth [inference]

negative regulation of cell growth [inference]

negative regulation of axon extension [inference]

negative regulation of axon extension involved in axon guidance

negative regulation of developmental growth [inference]

negative regulation of axon extension [inference]

negative regulation of axon extension involved in axon guidance

negative regulation of cellular process [inference]

negative regulation of cell growth [inference]

negative regulation of axon extension [inference]

negative regulation of axon extension involved in axon guidance

negative regulation of cell differentiation [inference]

negative regulation of cell development [inference]

negative regulation of neurogenesis [inference]

negative regulation of axonogenesis [inference]

negative regulation of axon extension [inference]

negative regulation of axon extension involved in axon guidance

negative regulation of cellular component organization [inference]

negative regulation of cell projection organization [inference]

negative regulation of neuron projection development [inference]

negative regulation of axonogenesis [inference]

negative regulation of axon extension [inference]

negative regulation of axon extension involved in axon guidance

negative regulation of response to stimulus [inference]

negative regulation of response to external stimulus [inference]

negative regulation of chemotaxis [inference]

negative regulation of axon extension involved in axon guidance

negative regulation of developmental process [inference]

negative regulation of cell differentiation [inference]

negative regulation of cell development [inference]

negative regulation of neurogenesis [inference]

negative regulation of axonogenesis [inference]

negative regulation of axon extension [inference]

negative regulation of axon extension involved in axon guidance

negative regulation of developmental growth [inference]

negative regulation of axon extension [inference]

negative regulation of axon extension involved in axon guidance

negative regulation of nervous system development [inference]

negative regulation of neurogenesis [inference]

negative regulation of axonogenesis [inference]

negative regulation of axon extension [inference]

negative regulation of axon extension involved in axon guidance

negative regulation of multicellular organismal process [inference]

negative regulation of nervous system development [inference]

negative regulation of neurogenesis [inference]

negative regulation of axonogenesis [inference]

negative regulation of axon extension [inference]

negative regulation of axon extension involved in axon guidance

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of Wnt signaling pathway

regulation of Wnt signaling pathway [inference]

positive regulation of Wnt signaling pathway

regulation of response to external stimulus [inference]

negative regulation of response to external stimulus [inference]

negative regulation of chemotaxis [inference]

negative regulation of axon extension involved in axon guidance

regulation of chemotaxis [inference]

negative regulation of chemotaxis [inference]

negative regulation of axon extension involved in axon guidance

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of Wnt signaling pathway

negative regulation of response to stimulus [inference]

negative regulation of response to external stimulus [inference]

negative regulation of chemotaxis [inference]

negative regulation of axon extension involved in axon guidance

regulation of developmental process [inference]

regulation of anatomical structure morphogenesis [inference]

regulation of axonogenesis [inference]

regulation of collateral sprouting [inference]

positive regulation of collateral sprouting [inference]

positive regulation of collateral sprouting in absence of injury

regulation of collateral sprouting in absence of injury [inference]

positive regulation of collateral sprouting in absence of injury

negative regulation of axonogenesis [inference]

negative regulation of axon extension [inference]

negative regulation of axon extension involved in axon guidance

positive regulation of axonogenesis [inference]

positive regulation of collateral sprouting [inference]

positive regulation of collateral sprouting in absence of injury

regulation of cell differentiation [inference]

negative regulation of cell differentiation [inference]

negative regulation of cell development [inference]

negative regulation of neurogenesis [inference]

negative regulation of axonogenesis [inference]

negative regulation of axon extension [inference]

negative regulation of axon extension involved in axon guidance

positive regulation of cell differentiation [inference]

positive regulation of cell development [inference]

positive regulation of neurogenesis [inference]

positive regulation of axonogenesis [inference]

positive regulation of collateral sprouting [inference]

positive regulation of collateral sprouting in absence of injury

positive regulation of osteoblast differentiation

regulation of osteoblast differentiation [inference]

positive regulation of osteoblast differentiation

regulation of cell development [inference]

positive regulation of cell development [inference]

positive regulation of neurogenesis [inference]

positive regulation of axonogenesis [inference]

positive regulation of collateral sprouting [inference]

positive regulation of collateral sprouting in absence of injury

negative regulation of cell development [inference]

negative regulation of neurogenesis [inference]

negative regulation of axonogenesis [inference]

negative regulation of axon extension [inference]

negative regulation of axon extension involved in axon guidance

regulation of neurogenesis

negative regulation of neurogenesis [inference]

negative regulation of axonogenesis [inference]

negative regulation of axon extension [inference]

negative regulation of axon extension involved in axon guidance

positive regulation of neurogenesis [inference]

positive regulation of axonogenesis [inference]

positive regulation of collateral sprouting [inference]

positive regulation of collateral sprouting in absence of injury

regulation of stem cell differentiation [inference]

regulation of mesenchymal stem cell differentiation

regulation of developmental growth [inference]

regulation of axon extension [inference]

negative regulation of axon extension [inference]

negative regulation of axon extension involved in axon guidance

regulation of axon extension involved in axon guidance [inference]

negative regulation of axon extension involved in axon guidance

positive regulation of developmental growth [inference]

positive regulation of collateral sprouting [inference]

positive regulation of collateral sprouting in absence of injury

negative regulation of developmental growth [inference]

negative regulation of axon extension [inference]

negative regulation of axon extension involved in axon guidance

regulation of collateral sprouting [inference]

positive regulation of collateral sprouting [inference]

positive regulation of collateral sprouting in absence of injury

regulation of collateral sprouting in absence of injury [inference]

positive regulation of collateral sprouting in absence of injury

negative regulation of developmental process [inference]

negative regulation of cell differentiation [inference]

negative regulation of cell development [inference]

negative regulation of neurogenesis [inference]

negative regulation of axonogenesis [inference]

negative regulation of axon extension [inference]

negative regulation of axon extension involved in axon guidance

negative regulation of developmental growth [inference]

negative regulation of axon extension [inference]

negative regulation of axon extension involved in axon guidance

negative regulation of nervous system development [inference]

negative regulation of neurogenesis [inference]

negative regulation of axonogenesis [inference]

negative regulation of axon extension [inference]

negative regulation of axon extension involved in axon guidance

positive regulation of developmental process [inference]

positive regulation of cell differentiation [inference]

positive regulation of cell development [inference]

positive regulation of neurogenesis [inference]

positive regulation of axonogenesis [inference]

positive regulation of collateral sprouting [inference]

positive regulation of collateral sprouting in absence of injury

positive regulation of osteoblast differentiation

positive regulation of developmental growth [inference]

positive regulation of collateral sprouting [inference]

positive regulation of collateral sprouting in absence of injury

positive regulation of nervous system development [inference]

positive regulation of neurogenesis [inference]

positive regulation of axonogenesis [inference]

positive regulation of collateral sprouting [inference]

positive regulation of collateral sprouting in absence of injury

regulation of multicellular organismal development [inference]

regulation of nervous system development [inference]

regulation of neurogenesis

negative regulation of neurogenesis [inference]

negative regulation of axonogenesis [inference]

negative regulation of axon extension [inference]

negative regulation of axon extension involved in axon guidance

positive regulation of neurogenesis [inference]

positive regulation of axonogenesis [inference]

positive regulation of collateral sprouting [inference]

positive regulation of collateral sprouting in absence of injury

negative regulation of nervous system development [inference]

negative regulation of neurogenesis [inference]

negative regulation of axonogenesis [inference]

negative regulation of axon extension [inference]

negative regulation of axon extension involved in axon guidance

positive regulation of nervous system development [inference]

positive regulation of neurogenesis [inference]

positive regulation of axonogenesis [inference]

positive regulation of collateral sprouting [inference]

positive regulation of collateral sprouting in absence of injury

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

Wnt signaling pathway [inference]

canonical Wnt signaling pathway

regulation of cell communication [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of Wnt signaling pathway

regulation of Wnt signaling pathway [inference]

positive regulation of Wnt signaling pathway

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of Wnt signaling pathway

regulation of cellular metabolic process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

positive regulation of gene expression

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

regulation of cell differentiation [inference]

negative regulation of cell differentiation [inference]

negative regulation of cell development [inference]

negative regulation of neurogenesis [inference]

negative regulation of axonogenesis [inference]

negative regulation of axon extension [inference]

negative regulation of axon extension involved in axon guidance

positive regulation of cell differentiation [inference]

positive regulation of cell development [inference]

positive regulation of neurogenesis [inference]

positive regulation of axonogenesis [inference]

positive regulation of collateral sprouting [inference]

positive regulation of collateral sprouting in absence of injury

positive regulation of osteoblast differentiation

regulation of osteoblast differentiation [inference]

positive regulation of osteoblast differentiation

regulation of cell development [inference]

positive regulation of cell development [inference]

positive regulation of neurogenesis [inference]

positive regulation of axonogenesis [inference]

positive regulation of collateral sprouting [inference]

positive regulation of collateral sprouting in absence of injury

negative regulation of cell development [inference]

negative regulation of neurogenesis [inference]

negative regulation of axonogenesis [inference]

negative regulation of axon extension [inference]

negative regulation of axon extension involved in axon guidance

regulation of neurogenesis

negative regulation of neurogenesis [inference]

negative regulation of axonogenesis [inference]

negative regulation of axon extension [inference]

negative regulation of axon extension involved in axon guidance

positive regulation of neurogenesis [inference]

positive regulation of axonogenesis [inference]

positive regulation of collateral sprouting [inference]

positive regulation of collateral sprouting in absence of injury

regulation of stem cell differentiation [inference]

regulation of mesenchymal stem cell differentiation

positive regulation of cellular process [inference]

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of Wnt signaling pathway

positive regulation of cell growth [inference]

positive regulation of collateral sprouting [inference]

positive regulation of collateral sprouting in absence of injury

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of cell differentiation [inference]

positive regulation of cell development [inference]

positive regulation of neurogenesis [inference]

positive regulation of axonogenesis [inference]

positive regulation of collateral sprouting [inference]

positive regulation of collateral sprouting in absence of injury

positive regulation of osteoblast differentiation

positive regulation of cellular component organization [inference]

positive regulation of cell projection organization [inference]

positive regulation of axonogenesis [inference]

positive regulation of collateral sprouting [inference]

positive regulation of collateral sprouting in absence of injury

negative regulation of cellular process [inference]

negative regulation of cell growth [inference]

negative regulation of axon extension [inference]

negative regulation of axon extension involved in axon guidance

negative regulation of cell differentiation [inference]

negative regulation of cell development [inference]

negative regulation of neurogenesis [inference]

negative regulation of axonogenesis [inference]

negative regulation of axon extension [inference]

negative regulation of axon extension involved in axon guidance

negative regulation of cellular component organization [inference]

negative regulation of cell projection organization [inference]

negative regulation of neuron projection development [inference]

negative regulation of axonogenesis [inference]

negative regulation of axon extension [inference]

negative regulation of axon extension involved in axon guidance

regulation of cellular component organization [inference]

regulation of cell growth [inference]

positive regulation of cell growth [inference]

positive regulation of collateral sprouting [inference]

positive regulation of collateral sprouting in absence of injury

negative regulation of cell growth [inference]

negative regulation of axon extension [inference]

negative regulation of axon extension involved in axon guidance

regulation of extent of cell growth [inference]

regulation of axon extension [inference]

negative regulation of axon extension [inference]

negative regulation of axon extension involved in axon guidance

regulation of axon extension involved in axon guidance [inference]

negative regulation of axon extension involved in axon guidance

regulation of collateral sprouting [inference]

positive regulation of collateral sprouting [inference]

positive regulation of collateral sprouting in absence of injury

regulation of collateral sprouting in absence of injury [inference]

positive regulation of collateral sprouting in absence of injury

regulation of cell projection organization [inference]

negative regulation of cell projection organization [inference]

negative regulation of neuron projection development [inference]

negative regulation of axonogenesis [inference]

negative regulation of axon extension [inference]

negative regulation of axon extension involved in axon guidance

positive regulation of cell projection organization [inference]

positive regulation of axonogenesis [inference]

positive regulation of collateral sprouting [inference]

positive regulation of collateral sprouting in absence of injury

regulation of plasma membrane bounded cell projection organization [inference]

regulation of neuron projection development [inference]

negative regulation of neuron projection development [inference]

negative regulation of axonogenesis [inference]

negative regulation of axon extension [inference]

negative regulation of axon extension involved in axon guidance

regulation of axonogenesis [inference]

regulation of collateral sprouting [inference]

positive regulation of collateral sprouting [inference]

positive regulation of collateral sprouting in absence of injury

regulation of collateral sprouting in absence of injury [inference]

positive regulation of collateral sprouting in absence of injury

negative regulation of axonogenesis [inference]

negative regulation of axon extension [inference]

negative regulation of axon extension involved in axon guidance

positive regulation of axonogenesis [inference]

positive regulation of collateral sprouting [inference]

positive regulation of collateral sprouting in absence of injury

negative regulation of cellular component organization [inference]

negative regulation of cell projection organization [inference]

negative regulation of neuron projection development [inference]

negative regulation of axonogenesis [inference]

negative regulation of axon extension [inference]

negative regulation of axon extension involved in axon guidance

positive regulation of cellular component organization [inference]

positive regulation of cell projection organization [inference]

positive regulation of axonogenesis [inference]

positive regulation of collateral sprouting [inference]

positive regulation of collateral sprouting in absence of injury

regulation of multicellular organismal process [inference]

positive regulation of multicellular organismal process [inference]

positive regulation of nervous system development [inference]

positive regulation of neurogenesis [inference]

positive regulation of axonogenesis [inference]

positive regulation of collateral sprouting [inference]

positive regulation of collateral sprouting in absence of injury

negative regulation of multicellular organismal process [inference]

negative regulation of nervous system development [inference]

negative regulation of neurogenesis [inference]

negative regulation of axonogenesis [inference]

negative regulation of axon extension [inference]

negative regulation of axon extension involved in axon guidance

regulation of multicellular organismal development [inference]

regulation of nervous system development [inference]

regulation of neurogenesis

negative regulation of neurogenesis [inference]

negative regulation of axonogenesis [inference]

negative regulation of axon extension [inference]

negative regulation of axon extension involved in axon guidance

positive regulation of neurogenesis [inference]

positive regulation of axonogenesis [inference]

positive regulation of collateral sprouting [inference]

positive regulation of collateral sprouting in absence of injury

negative regulation of nervous system development [inference]

negative regulation of neurogenesis [inference]

negative regulation of axonogenesis [inference]

negative regulation of axon extension [inference]

negative regulation of axon extension involved in axon guidance

positive regulation of nervous system development [inference]

positive regulation of neurogenesis [inference]

positive regulation of axonogenesis [inference]

positive regulation of collateral sprouting [inference]

positive regulation of collateral sprouting in absence of injury

Displaying entries **1 - 5** of 11 in total

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GO Term	Evidence Code	PMID
extracellular region	TAS
extracellular space	TAS	18313787
extracellular space	IBA
endoplasmic reticulum lumen	TAS
Golgi lumen	TAS

GO Hierarchy

cellular component

protein-containing complex [inference]

Wnt signalosome

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

organelle membrane [inference]

vesicle membrane [inference]

cytoplasmic vesicle membrane [inference]

endocytic vesicle membrane

bounding membrane of organelle [inference]

endocytic vesicle membrane

external encapsulating structure [inference]

extracellular matrix

membrane-enclosed lumen [inference]

organelle lumen [inference]

intracellular organelle lumen [inference]

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

extracellular vesicle [inference]

extracellular exosome

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

extracellular organelle [inference]

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

Displaying entries **1 - 5** of 7 in total

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GO Term	Evidence Code	PMID
frizzled binding	IBA
frizzled binding	IPI	10557084 18313787
cytokine activity	IBA
protein binding	IPI	18313787 21314951 26902720 31036956
protein domain specific binding	IEA

GO Hierarchy

molecular function

binding [inference]

protein binding

signaling receptor binding [inference]

G protein-coupled receptor binding [inference]

frizzled binding

receptor ligand activity

cytokine activity

protein domain specific binding

molecular function regulator activity [inference]

signaling receptor regulator activity [inference]

signaling receptor activator activity [inference]

receptor ligand activity

cytokine activity

molecular function activator activity [inference]

signaling receptor activator activity [inference]

receptor ligand activity

cytokine activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Wnt

Functional Category

J: Translation, ribosomal structure and biogenesis
K: Transcription
T: Signal transduction mechanisms

Displaying **all 5** entries
Gene Ontology
canonical Wnt signaling pathway
cell fate commitment
cytokine activity
neuron differentiation
signaling receptor binding

Displaying **all 3** entries
InterPro
Wnt protein, conserved site
Wnt, C-terminal domain
Wnt

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:0112192	tetraamelia syndrome 1	Alliance of Genome Resources

Ortholog

Displaying entries **1 - 10** of 73 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Xenopus tropicalis	7473	Xenbase:XB-GENE-479567
Mus musculus	22415	Xenbase:XB-GENE-479567	MOUSE05656
Rattus norvegicus	24882		RATNO00772
Xenopus tropicalis	35975	Xenbase:XB-GENE-479567
Ciona intestinalis	445715		CIOIN11514
Bos taurus	540753		BOVIN13576
Danio rerio	569420		DANRE46860
Canis lupus familiaris	609107		CANLF18523
Macaca mulatta	716909		MACMU15249
Oryctolagus cuniculus	100009033		RABIT07839

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Last updated: December 8, 2025