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C2 calcium-dependent domain containing 5

Summary

Gene Symbol

C2cd5

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

74741

PubChem

74741

Alliance of Genome Resources

MGI:1921991

Annotation

Keyword

Alternative splicing
Calcium
Cell membrane
Cell projection
Cytoplasm
Cytoplasmic vesicle
Lipid-binding
Metal-binding
Phosphoprotein
Protein transport
Proteomics identification
Reference proteome

Proteins

Displaying **all 4** entries
UniProt	Protein Name
Q7TPS5	138 kDa C2 domain-containing phosphoprotein
A0A0N4SW93
Q3TSE2
E9Q026

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	PMID
positive regulation of protein targeting to membrane	IBA ISO ISS
vesicle fusion	IMP	21907143
positive regulation of vesicle fusion	IBA IMP ISO	21907143
intracellular protein transmembrane transport	IBA ISO ISS
insulin receptor signaling pathway	IMP ISO	21907143

GO Hierarchy

biological process

cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

enzyme-linked receptor protein signaling pathway [inference]

transmembrane receptor protein tyrosine kinase signaling pathway [inference]

insulin receptor signaling pathway

cellular localization [inference]

intracellular transport [inference]

intracellular protein transport [inference]

intracellular protein transmembrane transport

localization within membrane [inference]

protein localization to membrane [inference]

protein localization to plasma membrane

cellular macromolecule localization [inference]

protein localization [inference]

establishment of protein localization [inference]

protein transport [inference]

intracellular protein transport [inference]

intracellular protein transmembrane transport

protein transmembrane transport [inference]

intracellular protein transmembrane transport

protein localization to membrane [inference]

protein localization to plasma membrane

protein localization to cell periphery [inference]

protein localization to plasma membrane

transmembrane transport [inference]

protein transmembrane transport [inference]

intracellular protein transmembrane transport

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

vesicle organization [inference]

vesicle fusion

organelle fusion [inference]

organelle membrane fusion [inference]

vesicle fusion

membrane organization [inference]

membrane fusion [inference]

organelle membrane fusion [inference]

vesicle fusion

localization [inference]

macromolecule localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

establishment of protein localization [inference]

protein transport [inference]

intracellular protein transport [inference]

intracellular protein transmembrane transport

protein transmembrane transport [inference]

intracellular protein transmembrane transport

protein localization to membrane [inference]

protein localization to plasma membrane

protein localization to cell periphery [inference]

protein localization to plasma membrane

establishment of localization [inference]

transport [inference]

intracellular transport [inference]

intracellular protein transport [inference]

intracellular protein transmembrane transport

transmembrane transport [inference]

protein transmembrane transport [inference]

intracellular protein transmembrane transport

organic substance transport [inference]

protein transport [inference]

intracellular protein transport [inference]

intracellular protein transmembrane transport

protein transmembrane transport [inference]

intracellular protein transmembrane transport

nitrogen compound transport [inference]

protein transport [inference]

intracellular protein transport [inference]

intracellular protein transmembrane transport

protein transmembrane transport [inference]

intracellular protein transmembrane transport

establishment of protein localization [inference]

protein transport [inference]

intracellular protein transport [inference]

intracellular protein transmembrane transport

protein transmembrane transport [inference]

intracellular protein transmembrane transport

establishment of localization in cell [inference]

intracellular transport [inference]

intracellular protein transport [inference]

intracellular protein transmembrane transport

cellular localization [inference]

intracellular transport [inference]

intracellular protein transport [inference]

intracellular protein transmembrane transport

localization within membrane [inference]

protein localization to membrane [inference]

protein localization to plasma membrane

cellular macromolecule localization [inference]

protein localization [inference]

establishment of protein localization [inference]

protein transport [inference]

intracellular protein transport [inference]

intracellular protein transmembrane transport

protein transmembrane transport [inference]

intracellular protein transmembrane transport

protein localization to membrane [inference]

protein localization to plasma membrane

protein localization to cell periphery [inference]

protein localization to plasma membrane

biological regulation [inference]

regulation of biological process [inference]

regulation of localization [inference]

regulation of transport [inference]

regulation of transmembrane transport [inference]

regulation of glucose transmembrane transport [inference]

positive regulation of glucose transmembrane transport

positive regulation of glucose import

regulation of glucose import [inference]

positive regulation of glucose import

positive regulation of transmembrane transport [inference]

positive regulation of glucose transmembrane transport

positive regulation of glucose import

positive regulation of transport [inference]

positive regulation of vesicle fusion

positive regulation of transmembrane transport [inference]

positive regulation of glucose transmembrane transport

positive regulation of glucose import

regulation of vesicle-mediated transport [inference]

regulation of vesicle fusion [inference]

positive regulation of vesicle fusion

regulation of cellular localization [inference]

regulation of protein localization [inference]

regulation of establishment of protein localization [inference]

regulation of protein targeting [inference]

regulation of protein targeting to membrane [inference]

positive regulation of protein targeting to membrane

positive regulation of establishment of protein localization [inference]

positive regulation of protein targeting to membrane

positive regulation of protein localization [inference]

positive regulation of establishment of protein localization [inference]

positive regulation of protein targeting to membrane

positive regulation of protein localization to membrane [inference]

positive regulation of protein targeting to membrane

regulation of protein localization to membrane [inference]

regulation of protein targeting to membrane [inference]

positive regulation of protein targeting to membrane

positive regulation of protein localization to membrane [inference]

positive regulation of protein targeting to membrane

positive regulation of biological process [inference]

positive regulation of cellular process [inference]

positive regulation of transmembrane transport [inference]

positive regulation of glucose transmembrane transport

positive regulation of glucose import

positive regulation of cellular component organization [inference]

positive regulation of organelle organization [inference]

positive regulation of vesicle fusion

positive regulation of protein localization [inference]

positive regulation of establishment of protein localization [inference]

positive regulation of protein targeting to membrane

positive regulation of protein localization to membrane [inference]

positive regulation of protein targeting to membrane

positive regulation of transport [inference]

positive regulation of vesicle fusion

positive regulation of transmembrane transport [inference]

positive regulation of glucose transmembrane transport

positive regulation of glucose import

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

enzyme-linked receptor protein signaling pathway [inference]

transmembrane receptor protein tyrosine kinase signaling pathway [inference]

insulin receptor signaling pathway

regulation of transmembrane transport [inference]

regulation of glucose transmembrane transport [inference]

positive regulation of glucose transmembrane transport

positive regulation of glucose import

regulation of glucose import [inference]

positive regulation of glucose import

positive regulation of transmembrane transport [inference]

positive regulation of glucose transmembrane transport

positive regulation of glucose import

positive regulation of cellular process [inference]

positive regulation of transmembrane transport [inference]

positive regulation of glucose transmembrane transport

positive regulation of glucose import

positive regulation of cellular component organization [inference]

positive regulation of organelle organization [inference]

positive regulation of vesicle fusion

positive regulation of protein localization [inference]

positive regulation of establishment of protein localization [inference]

positive regulation of protein targeting to membrane

positive regulation of protein localization to membrane [inference]

positive regulation of protein targeting to membrane

regulation of cellular component organization [inference]

regulation of organelle organization [inference]

positive regulation of organelle organization [inference]

positive regulation of vesicle fusion

regulation of vesicle fusion [inference]

positive regulation of vesicle fusion

positive regulation of cellular component organization [inference]

positive regulation of organelle organization [inference]

positive regulation of vesicle fusion

regulation of cellular localization [inference]

regulation of protein localization [inference]

regulation of establishment of protein localization [inference]

regulation of protein targeting [inference]

regulation of protein targeting to membrane [inference]

positive regulation of protein targeting to membrane

positive regulation of establishment of protein localization [inference]

positive regulation of protein targeting to membrane

positive regulation of protein localization [inference]

positive regulation of establishment of protein localization [inference]

positive regulation of protein targeting to membrane

positive regulation of protein localization to membrane [inference]

positive regulation of protein targeting to membrane

regulation of protein localization to membrane [inference]

regulation of protein targeting to membrane [inference]

positive regulation of protein targeting to membrane

positive regulation of protein localization to membrane [inference]

positive regulation of protein targeting to membrane

regulation of vesicle-mediated transport [inference]

regulation of vesicle fusion [inference]

positive regulation of vesicle fusion

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
centriolar satellite	ISO
cell cortex	ISO ISS
cytoplasmic vesicle membrane	ISO ISS
ruffle membrane	ISO ISS
plasma membrane	IBA IDA ISO TAS	21907143

GO Hierarchy

cellular component

cellular anatomical entity [inference]

cytoplasm [inference]

cell cortex

cytosol

membrane [inference]

plasma membrane

organelle membrane [inference]

vesicle membrane [inference]

cytoplasmic vesicle membrane

plasma membrane region [inference]

cell projection membrane [inference]

ruffle membrane

leading edge membrane [inference]

ruffle membrane

centriolar satellite

Displaying **all 2** entries
GO Term	Evidence Code	PMID
calcium-dependent phospholipid binding	IBA ISO ISS
calcium ion binding	IBA IDA ISO	21907143

GO Hierarchy

molecular function

binding [inference]

lipid binding [inference]

phospholipid binding [inference]

calcium-dependent phospholipid binding

ion binding [inference]

cation binding [inference]

metal ion binding [inference]

calcium ion binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Rodentia

Group Name

C2 domain-containing protein 5

Functional Category

E: Amino acid transport and metabolism
H: Coenzyme transport and metabolism
T: Signal transduction mechanisms

Displaying **all 6** entries
Gene Ontology
calcium ion binding
calcium-dependent phospholipid binding
intracellular protein transmembrane transport
positive regulation of glucose transmembrane transport
positive regulation of protein targeting to membrane
positive regulation of vesicle fusion

Displaying **all 4** entries
InterPro
C2 domain superfamily
C2 domain-containing protein 5
C2 domain
C2CD5, C2 domain

Ortholog

Displaying entries **11 - 20** of **111** in total

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Species	Gene ID	OrthoDB	Orthologous MAtrix
Macaca mulatta	100430610		MACMU03948
Ailuropoda melanoleuca	100464142		AILME16811
Sus scrofa	100521725		PIGXX26021
Anolis carolinensis	100560452		ANOCA06728
Nomascus leucogenys	100582373		NOMLE22717
Monodelphis domestica	100618765		MONDO35113
Loxodonta africana	100660073		LOXAF19165
Oreochromis niloticus	100708237		ORENI69285
Cavia porcellus	100721333	10141_0:002876	CAVPO13195
Cricetulus griseus	100766087	10029_0:004a0e