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Guidelines

MIRAGE

selenoprotein N

Summary

Gene Symbol

Selenon

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

74777

KEGG Gene ID

PubChem

74777

Alliance of Genome Resources

MGI:2151208

Annotation

Keyword

Endoplasmic reticulum
Glycoprotein
Membrane
Oxidoreductase
Reference proteome
Repeat
Selenocysteine
Signal

Proteins

Displaying 1 entry
UniProt	Protein Name
D3Z2R5

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **41 - 45** of 45 in total

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GO Term	Evidence Code	PMID
cellular response to caffeine	IMP
positive regulation of response to oxidative stress	ISS
positive regulation of response to oxidative stress	ISO
positive regulation of response to oxidative stress	IEA
obsolete mitochondrion-endoplasmic reticulum membrane tethering	IMP

GO Hierarchy

biological process

cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

enzyme-linked receptor protein signaling pathway [inference]

cell surface receptor protein serine/threonine kinase signaling pathway [inference]

transforming growth factor beta receptor superfamily signaling pathway [inference]

transforming growth factor beta receptor signaling pathway

metabolic process [inference]

generation of precursor metabolites and energy

energy derivation by oxidation of organic compounds [inference]

energy reserve metabolic process

phosphorus metabolic process [inference]

organophosphate metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

ATP metabolic process

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

ATP metabolic process

nucleoside triphosphate metabolic process [inference]

purine nucleoside triphosphate metabolic process [inference]

purine ribonucleoside triphosphate metabolic process [inference]

ATP metabolic process

ribose phosphate metabolic process [inference]

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

ATP metabolic process

biosynthetic process [inference]

macromolecule biosynthetic process [inference]

gene expression

macromolecule metabolic process [inference]

macromolecule biosynthetic process [inference]

gene expression

primary metabolic process [inference]

carbohydrate metabolic process [inference]

monosaccharide metabolic process [inference]

L-ascorbic acid metabolic process

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

ATP metabolic process

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

ATP metabolic process

nucleoside triphosphate metabolic process [inference]

purine nucleoside triphosphate metabolic process [inference]

purine ribonucleoside triphosphate metabolic process [inference]

ATP metabolic process

small molecule metabolic process [inference]

monosaccharide metabolic process [inference]

L-ascorbic acid metabolic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

L-ascorbic acid metabolic process

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

ATP metabolic process

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

ATP metabolic process

nucleoside triphosphate metabolic process [inference]

purine nucleoside triphosphate metabolic process [inference]

purine ribonucleoside triphosphate metabolic process [inference]

ATP metabolic process

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

ATP metabolic process

carbohydrate derivative metabolic process [inference]

ribose phosphate metabolic process [inference]

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

ATP metabolic process

lactone metabolic process [inference]

L-ascorbic acid metabolic process

membrane docking [inference]

membrane to membrane docking

cellular developmental process [inference]

cell differentiation [inference]

skeletal muscle cell differentiation [inference]

skeletal muscle satellite cell differentiation

cell development [inference]

muscle cell development [inference]

striated muscle cell development [inference]

myotube cell development [inference]

skeletal muscle fiber development

cellular response to stimulus [inference]

cellular response to stress [inference]

response to endoplasmic reticulum stress

cellular response to chemical stress [inference]

cellular response to oxidative stress

cellular response to chemical stimulus [inference]

cellular response to chemical stress [inference]

cellular response to oxidative stress

cellular response to nitrogen compound [inference]

cellular response to alkaloid [inference]

cellular response to caffeine

transmembrane transport [inference]

carbohydrate transmembrane transport [inference]

monosaccharide transmembrane transport [inference]

L-ascorbic acid transmembrane transport

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

calcium ion transmembrane transport [inference]

mitochondrial calcium ion transmembrane transport

vitamin transmembrane transport [inference]

L-ascorbic acid transmembrane transport

carboxylic acid transmembrane transport [inference]

L-ascorbic acid transmembrane transport

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

mitochondrion organization

extracellular structure organization [inference]

extracellular matrix organization [inference]

collagen fibril organization

external encapsulating structure organization [inference]

extracellular matrix organization [inference]

collagen fibril organization

membrane organization

cellular component biogenesis [inference]

membrane biogenesis

multicellular organismal process [inference]

system process [inference]

muscle system process [inference]

muscle contraction [inference]

striated muscle contraction [inference]

skeletal muscle contraction [inference]

involuntary skeletal muscle contraction [inference]

diaphragm contraction

respiratory system process

diaphragm contraction

multicellular organismal response to stress

developmental process [inference]

anatomical structure development [inference]

regeneration [inference]

tissue regeneration [inference]

skeletal muscle tissue regeneration

cell development [inference]

muscle cell development [inference]

striated muscle cell development [inference]

myotube cell development [inference]

skeletal muscle fiber development

animal gross anatomical part developmental process [inference]

tissue development [inference]

muscle tissue development [inference]

striated muscle tissue development [inference]

skeletal muscle tissue development

tissue regeneration [inference]

skeletal muscle tissue regeneration

cellular developmental process [inference]

cell differentiation [inference]

skeletal muscle cell differentiation [inference]

skeletal muscle satellite cell differentiation

cell development [inference]

muscle cell development [inference]

striated muscle cell development [inference]

myotube cell development [inference]

skeletal muscle fiber development

maintenance of cell number [inference]

skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration

growth [inference]

developmental growth [inference]

tissue regeneration [inference]

skeletal muscle tissue regeneration

homeostatic process [inference]

cellular homeostasis [inference]

cell redox homeostasis

chemical homeostasis [inference]

monoatomic ion homeostasis [inference]

monoatomic cation homeostasis [inference]

calcium ion homeostasis

inorganic ion homeostasis [inference]

calcium ion homeostasis

response to stimulus [inference]

response to stress [inference]

response to oxidative stress [inference]

cellular response to oxidative stress

cellular response to stress [inference]

response to endoplasmic reticulum stress

cellular response to chemical stress [inference]

cellular response to oxidative stress

multicellular organismal response to stress

response to activity [inference]

response to muscle activity [inference]

response to muscle activity involved in regulation of muscle adaptation

response to chemical [inference]

cellular response to chemical stimulus [inference]

cellular response to chemical stress [inference]

cellular response to oxidative stress

cellular response to nitrogen compound [inference]

cellular response to alkaloid [inference]

cellular response to caffeine

response to nitrogen compound [inference]

response to purine-containing compound [inference]

response to caffeine [inference]

cellular response to caffeine

cellular response to purine-containing compound [inference]

cellular response to caffeine

response to alkaloid [inference]

response to caffeine [inference]

cellular response to caffeine

cellular response to alkaloid [inference]

cellular response to caffeine

cellular response to nitrogen compound [inference]

cellular response to alkaloid [inference]

cellular response to caffeine

cellular response to stimulus [inference]

cellular response to stress [inference]

response to endoplasmic reticulum stress

cellular response to chemical stress [inference]

cellular response to oxidative stress

cellular response to chemical stimulus [inference]

cellular response to chemical stress [inference]

cellular response to oxidative stress

cellular response to nitrogen compound [inference]

cellular response to alkaloid [inference]

cellular response to caffeine

localization [inference]

establishment of localization [inference]

transport [inference]

monoatomic ion transport [inference]

monoatomic cation transport [inference]

metal ion transport [inference]

calcium ion transport

calcium ion import

calcium ion transmembrane transport [inference]

mitochondrial calcium ion transmembrane transport

monoatomic cation transmembrane transport [inference]

calcium ion transmembrane transport [inference]

mitochondrial calcium ion transmembrane transport

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

calcium ion transmembrane transport [inference]

mitochondrial calcium ion transmembrane transport

carbohydrate transport [inference]

carbohydrate transmembrane transport [inference]

monosaccharide transmembrane transport [inference]

L-ascorbic acid transmembrane transport

organic acid transport [inference]

carboxylic acid transport [inference]

carboxylic acid transmembrane transport [inference]

L-ascorbic acid transmembrane transport

vitamin transport [inference]

vitamin transmembrane transport [inference]

L-ascorbic acid transmembrane transport

transmembrane transport [inference]

carbohydrate transmembrane transport [inference]

monosaccharide transmembrane transport [inference]

L-ascorbic acid transmembrane transport

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

calcium ion transmembrane transport [inference]

mitochondrial calcium ion transmembrane transport

vitamin transmembrane transport [inference]

L-ascorbic acid transmembrane transport

carboxylic acid transmembrane transport [inference]

L-ascorbic acid transmembrane transport

biological regulation [inference]

regulation of biological process [inference]

regulation of localization [inference]

regulation of transport [inference]

regulation of transmembrane transport [inference]

regulation of transmembrane transporter activity [inference]

regulation of ryanodine-sensitive calcium-release channel activity

regulation of monoatomic ion transmembrane transport [inference]

regulation of monoatomic cation transmembrane transport [inference]

regulation of calcium ion transmembrane transport [inference]

regulation of release of sequestered calcium ion into cytosol [inference]

regulation of ryanodine-sensitive calcium-release channel activity

regulation of monoatomic ion transport [inference]

regulation of metal ion transport [inference]

regulation of calcium ion transport [inference]

regulation of calcium ion transmembrane transport [inference]

regulation of release of sequestered calcium ion into cytosol [inference]

regulation of ryanodine-sensitive calcium-release channel activity

regulation of monoatomic ion transmembrane transport [inference]

regulation of monoatomic cation transmembrane transport [inference]

regulation of calcium ion transmembrane transport [inference]

regulation of release of sequestered calcium ion into cytosol [inference]

regulation of ryanodine-sensitive calcium-release channel activity

positive regulation of biological process [inference]

positive regulation of cellular process [inference]

positive regulation of cell population proliferation [inference]

positive regulation of skeletal muscle cell proliferation

positive regulation of response to stimulus [inference]

positive regulation of response to oxidative stress

regulation of response to stimulus [inference]

positive regulation of response to stimulus [inference]

positive regulation of response to oxidative stress

regulation of response to stress [inference]

regulation of response to oxidative stress [inference]

positive regulation of response to oxidative stress

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

enzyme-linked receptor protein signaling pathway [inference]

cell surface receptor protein serine/threonine kinase signaling pathway [inference]

transforming growth factor beta receptor superfamily signaling pathway [inference]

transforming growth factor beta receptor signaling pathway

regulation of transmembrane transport [inference]

regulation of transmembrane transporter activity [inference]

regulation of ryanodine-sensitive calcium-release channel activity

regulation of monoatomic ion transmembrane transport [inference]

regulation of monoatomic cation transmembrane transport [inference]

regulation of calcium ion transmembrane transport [inference]

regulation of release of sequestered calcium ion into cytosol [inference]

regulation of ryanodine-sensitive calcium-release channel activity

regulation of cell population proliferation [inference]

positive regulation of cell population proliferation [inference]

positive regulation of skeletal muscle cell proliferation

regulation of skeletal muscle cell proliferation [inference]

positive regulation of skeletal muscle cell proliferation

positive regulation of cellular process [inference]

positive regulation of cell population proliferation [inference]

positive regulation of skeletal muscle cell proliferation

regulation of molecular function [inference]

regulation of transmembrane transporter activity [inference]

regulation of ryanodine-sensitive calcium-release channel activity

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	PMID
mitochondrion	IMP
endoplasmic reticulum	IMP
endoplasmic reticulum membrane	ISS
endoplasmic reticulum membrane	ISO
endoplasmic reticulum membrane	IBA

GO Hierarchy

cellular component

cellular anatomical structure [inference]

membrane [inference]

organelle membrane [inference]

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

organelle membrane contact site [inference]

mitochondria-associated endoplasmic reticulum membrane contact site

Displaying **all 3** entries
GO Term	Evidence Code	PMID
molecular_function	ND
calcium ion binding	IEA
oxidoreductase activity

GO Hierarchy

molecular function

catalytic activity [inference]

oxidoreductase activity

binding [inference]

small molecule binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding [inference]

calcium ion binding

Gene Ontology information from NCBI Gene and UniProt.

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:0110633	rigid spine muscular dystrophy 1	Alliance of Genome Resources

Ortholog

Displaying **all 3** entries
Species	Gene ID	Alliance of Genome Resources
Homo sapiens	57190	HGNC:15999
Danio rerio	352914	ZFIN:ZDB-GENE-030327-7
Xenopus tropicalis	394859	Xenbase:XB-GENE-6456840

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Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: April 6, 2026