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Wnt family member 11

Summary

Gene Symbol

WNT11

Organism

Homo sapiens (human)

External Links

NCBI Gene

7481

PubChem

7481

Alliance of Genome Resources

HGNC:12776

Annotation

Keyword

Developmental protein
Disulfide bond
Extracellular matrix
Glycoprotein
Lipoprotein
Reference proteome
Signal
Wnt signaling pathway

Proteins

Displaying 1 entry
UniProt	Protein Name
O96014

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 48 in total

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GO Term	Evidence Code	PMID
osteoblast differentiation	IEA
epithelial to mesenchymal transition	IEA
primary heart field specification	IEA
secondary heart field specification	IEA
outflow tract morphogenesis	IEA

GO Hierarchy

biological process

cellular process [inference]

establishment or maintenance of cell polarity [inference]

maintenance of cell polarity [inference]

maintenance of apical/basal cell polarity [inference]

maintenance of epithelial cell apical/basal polarity

establishment or maintenance of bipolar cell polarity [inference]

establishment or maintenance of apical/basal cell polarity [inference]

maintenance of apical/basal cell polarity [inference]

maintenance of epithelial cell apical/basal polarity

establishment or maintenance of epithelial cell apical/basal polarity [inference]

maintenance of epithelial cell apical/basal polarity

signal transduction

cell surface receptor signaling pathway [inference]

Wnt signaling pathway [inference]

non-canonical Wnt signaling pathway [inference]

Wnt signaling pathway, calcium modulating pathway

Wnt signaling pathway, planar cell polarity pathway

canonical Wnt signaling pathway

intracellular signal transduction

cell death [inference]

programmed cell death [inference]

apoptotic process [inference]

epithelial cell apoptotic process

cell population proliferation [inference]

cellular developmental process [inference]

cell differentiation [inference]

osteoblast differentiation

neuron differentiation

neuroendocrine cell differentiation

epithelial cell differentiation [inference]

columnar/cuboidal epithelial cell differentiation [inference]

neuroepithelial cell differentiation [inference]

neuroendocrine cell differentiation

mesenchymal cell differentiation [inference]

epithelial to mesenchymal transition

cell fate commitment

cellular response to stimulus [inference]

cellular response to chemical stimulus [inference]

cellular response to organic substance [inference]

cellular response to lipid [inference]

cellular response to retinoic acid

cellular response to oxygen-containing compound [inference]

cellular response to retinoic acid

cellular response to environmental stimulus [inference]

cellular response to abiotic stimulus [inference]

cellular response to mechanical stimulus

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cellular component assembly [inference]

cell junction assembly [inference]

cell-cell junction assembly [inference]

tight junction assembly [inference]

bicellular tight junction assembly

cell junction organization [inference]

cell junction assembly [inference]

cell-cell junction assembly [inference]

tight junction assembly [inference]

bicellular tight junction assembly

cell-cell junction organization [inference]

cell-cell junction assembly [inference]

tight junction assembly [inference]

bicellular tight junction assembly

tight junction organization [inference]

tight junction assembly [inference]

bicellular tight junction assembly

multicellular organismal process [inference]

pattern specification process [inference]

regionalization [inference]

specification of animal organ identity [inference]

heart field specification [inference]

developmental process [inference]

anatomical structure morphogenesis [inference]

outflow tract morphogenesis

animal organ morphogenesis [inference]

embryonic organ morphogenesis [inference]

notochord morphogenesis

tube morphogenesis [inference]

blood vessel morphogenesis [inference]

artery morphogenesis

cloacal septation

epithelial tube morphogenesis [inference]

renal tubule morphogenesis [inference]

nephron tubule morphogenesis [inference]

mesonephric tubule morphogenesis [inference]

ureteric bud morphogenesis

embryonic morphogenesis [inference]

embryonic organ morphogenesis [inference]

notochord morphogenesis

tissue morphogenesis [inference]

morphogenesis of an epithelium [inference]

convergent extension [inference]

convergent extension involved in axis elongation

epithelial tube morphogenesis [inference]

renal tubule morphogenesis [inference]

nephron tubule morphogenesis [inference]

mesonephric tubule morphogenesis [inference]

ureteric bud morphogenesis

nephron epithelium morphogenesis [inference]

nephron tubule morphogenesis [inference]

mesonephric tubule morphogenesis [inference]

ureteric bud morphogenesis

cardiac septum morphogenesis [inference]

ventricular septum morphogenesis

anatomical structure formation involved in morphogenesis [inference]

formation of primary germ layer [inference]

mesoderm formation [inference]

paraxial mesoderm formation

anatomical structure development [inference]

cardiac septum development [inference]

atrial septum development

tissue development [inference]

biomineral tissue development [inference]

bone mineralization

epithelium development [inference]

somite development

kidney epithelium development [inference]

mesonephric epithelium development [inference]

mesonephric tubule development [inference]

mesonephric duct development

nephric duct development [inference]

mesonephric duct development

mesenchyme development [inference]

lung-associated mesenchyme development

tube development [inference]

mesonephric tubule development [inference]

mesonephric duct development

nephric duct development [inference]

mesonephric duct development

animal organ development [inference]

gland development [inference]

adrenal gland development

system development [inference]

skeletal system development [inference]

embryonic skeletal system development

roof of mouth development [inference]

secondary palate development

cellular developmental process [inference]

cell differentiation [inference]

osteoblast differentiation

neuron differentiation

neuroendocrine cell differentiation

epithelial cell differentiation [inference]

columnar/cuboidal epithelial cell differentiation [inference]

neuroepithelial cell differentiation [inference]

neuroendocrine cell differentiation

mesenchymal cell differentiation [inference]

epithelial to mesenchymal transition

cell fate commitment

response to stimulus [inference]

response to external stimulus [inference]

response to mechanical stimulus [inference]

cellular response to mechanical stimulus

response to extracellular stimulus [inference]

response to nutrient levels

cellular response to external stimulus [inference]

cellular response to mechanical stimulus

response to abiotic stimulus [inference]

response to mechanical stimulus [inference]

cellular response to mechanical stimulus

cellular response to abiotic stimulus [inference]

cellular response to mechanical stimulus

response to chemical [inference]

response to organic substance [inference]

response to lipid [inference]

response to retinoic acid [inference]

cellular response to retinoic acid

cellular response to lipid [inference]

cellular response to retinoic acid

cellular response to organic substance [inference]

cellular response to lipid [inference]

cellular response to retinoic acid

cellular response to chemical stimulus [inference]

cellular response to organic substance [inference]

cellular response to lipid [inference]

cellular response to retinoic acid

cellular response to oxygen-containing compound [inference]

cellular response to retinoic acid

response to oxygen-containing compound [inference]

response to retinoic acid [inference]

cellular response to retinoic acid

cellular response to oxygen-containing compound [inference]

cellular response to retinoic acid

cellular response to stimulus [inference]

cellular response to chemical stimulus [inference]

cellular response to organic substance [inference]

cellular response to lipid [inference]

cellular response to retinoic acid

cellular response to oxygen-containing compound [inference]

cellular response to retinoic acid

cellular response to environmental stimulus [inference]

cellular response to abiotic stimulus [inference]

cellular response to mechanical stimulus

biological regulation [inference]

regulation of biological process [inference]

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of fibroblast growth factor production

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of transforming growth factor beta production [inference]

positive regulation of transforming growth factor beta2 production

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

negative regulation of cytokine production [inference]

negative regulation of fibroblast growth factor production

positive regulation of cytokine production [inference]

positive regulation of transforming growth factor beta production [inference]

positive regulation of transforming growth factor beta2 production

regulation of transforming growth factor beta production [inference]

regulation of transforming growth factor beta2 production [inference]

positive regulation of transforming growth factor beta2 production

positive regulation of transforming growth factor beta production [inference]

positive regulation of transforming growth factor beta2 production

regulation of fibroblast growth factor production [inference]

negative regulation of fibroblast growth factor production

regulation of DNA-templated transcription [inference]

positive regulation of transcription, DNA-templated

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of transforming growth factor beta production [inference]

positive regulation of transforming growth factor beta2 production

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of fibroblast growth factor production

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of transforming growth factor beta production [inference]

positive regulation of transforming growth factor beta2 production

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of fibroblast growth factor production

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

positive regulation of transcription, DNA-templated

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of fibroblast growth factor production

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of transforming growth factor beta production [inference]

positive regulation of transforming growth factor beta2 production

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of fibroblast growth factor production

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of fibroblast growth factor production

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of fibroblast growth factor production

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of transforming growth factor beta production [inference]

positive regulation of transforming growth factor beta2 production

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of transforming growth factor beta production [inference]

positive regulation of transforming growth factor beta2 production

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of transforming growth factor beta production [inference]

positive regulation of transforming growth factor beta2 production

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

regulation of cellular metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

regulation of RNA metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

positive regulation of transcription, DNA-templated

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of fibroblast growth factor production

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of transforming growth factor beta production [inference]

positive regulation of transforming growth factor beta2 production

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

negative regulation of cytokine production [inference]

negative regulation of fibroblast growth factor production

positive regulation of cytokine production [inference]

positive regulation of transforming growth factor beta production [inference]

positive regulation of transforming growth factor beta2 production

regulation of transforming growth factor beta production [inference]

regulation of transforming growth factor beta2 production [inference]

positive regulation of transforming growth factor beta2 production

positive regulation of transforming growth factor beta production [inference]

positive regulation of transforming growth factor beta2 production

regulation of fibroblast growth factor production [inference]

negative regulation of fibroblast growth factor production

regulation of DNA-templated transcription [inference]

positive regulation of transcription, DNA-templated

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of transforming growth factor beta production [inference]

positive regulation of transforming growth factor beta2 production

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of fibroblast growth factor production

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of transforming growth factor beta production [inference]

positive regulation of transforming growth factor beta2 production

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of fibroblast growth factor production

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

positive regulation of transcription, DNA-templated

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of fibroblast growth factor production

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of transforming growth factor beta production [inference]

positive regulation of transforming growth factor beta2 production

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

regulation of nitrogen compound metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

regulation of RNA metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

positive regulation of transcription, DNA-templated

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

negative regulation of cytokine production [inference]

negative regulation of fibroblast growth factor production

positive regulation of cytokine production [inference]

positive regulation of transforming growth factor beta production [inference]

positive regulation of transforming growth factor beta2 production

regulation of transforming growth factor beta production [inference]

regulation of transforming growth factor beta2 production [inference]

positive regulation of transforming growth factor beta2 production

positive regulation of transforming growth factor beta production [inference]

positive regulation of transforming growth factor beta2 production

regulation of fibroblast growth factor production [inference]

negative regulation of fibroblast growth factor production

regulation of DNA-templated transcription [inference]

positive regulation of transcription, DNA-templated

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of transforming growth factor beta production [inference]

positive regulation of transforming growth factor beta2 production

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of fibroblast growth factor production

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of transforming growth factor beta production [inference]

positive regulation of transforming growth factor beta2 production

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of fibroblast growth factor production

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

positive regulation of transcription, DNA-templated

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of transforming growth factor beta production [inference]

positive regulation of transforming growth factor beta2 production

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of fibroblast growth factor production

regulation of RNA metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

positive regulation of transcription, DNA-templated

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

regulation of primary metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

regulation of RNA metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

positive regulation of transcription, DNA-templated

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

regulation of signaling [inference]

regulation of signal transduction [inference]

negative regulation of signal transduction [inference]

negative regulation of Wnt signaling pathway [inference]

negative regulation of canonical Wnt signaling pathway

regulation of Wnt signaling pathway [inference]

negative regulation of Wnt signaling pathway [inference]

negative regulation of canonical Wnt signaling pathway

regulation of canonical Wnt signaling pathway [inference]

negative regulation of canonical Wnt signaling pathway

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of Wnt signaling pathway [inference]

negative regulation of canonical Wnt signaling pathway

positive regulation of biological process [inference]

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of transforming growth factor beta production [inference]

positive regulation of transforming growth factor beta2 production

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of transforming growth factor beta production [inference]

positive regulation of transforming growth factor beta2 production

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of transforming growth factor beta production [inference]

positive regulation of transforming growth factor beta2 production

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of cellular process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of transforming growth factor beta production [inference]

positive regulation of transforming growth factor beta2 production

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of programmed cell death [inference]

positive regulation of apoptotic process [inference]

positive regulation of epithelial cell apoptotic process

positive regulation of multicellular organismal process [inference]

positive regulation of cytokine production [inference]

positive regulation of transforming growth factor beta production [inference]

positive regulation of transforming growth factor beta2 production

negative regulation of biological process [inference]

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of fibroblast growth factor production

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of fibroblast growth factor production

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of fibroblast growth factor production

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of Wnt signaling pathway [inference]

negative regulation of canonical Wnt signaling pathway

negative regulation of cellular process [inference]

negative regulation of cell population proliferation [inference]

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of Wnt signaling pathway [inference]

negative regulation of canonical Wnt signaling pathway

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of fibroblast growth factor production

negative regulation of response to stimulus [inference]

negative regulation of signal transduction [inference]

negative regulation of Wnt signaling pathway [inference]

negative regulation of canonical Wnt signaling pathway

negative regulation of developmental process [inference]

negative regulation of cartilage development

negative regulation of multicellular organismal process [inference]

negative regulation of cytokine production [inference]

negative regulation of fibroblast growth factor production

negative regulation of cartilage development

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

negative regulation of signal transduction [inference]

negative regulation of Wnt signaling pathway [inference]

negative regulation of canonical Wnt signaling pathway

regulation of Wnt signaling pathway [inference]

negative regulation of Wnt signaling pathway [inference]

negative regulation of canonical Wnt signaling pathway

regulation of canonical Wnt signaling pathway [inference]

negative regulation of canonical Wnt signaling pathway

negative regulation of response to stimulus [inference]

negative regulation of signal transduction [inference]

negative regulation of Wnt signaling pathway [inference]

negative regulation of canonical Wnt signaling pathway

regulation of developmental process [inference]

negative regulation of developmental process [inference]

negative regulation of cartilage development

regulation of multicellular organismal development [inference]

regulation of cartilage development [inference]

negative regulation of cartilage development

regulation of cellular process [inference]

signal transduction

cell surface receptor signaling pathway [inference]

Wnt signaling pathway [inference]

non-canonical Wnt signaling pathway [inference]

Wnt signaling pathway, calcium modulating pathway

Wnt signaling pathway, planar cell polarity pathway

canonical Wnt signaling pathway

intracellular signal transduction

regulation of cell communication [inference]

regulation of signal transduction [inference]

negative regulation of signal transduction [inference]

negative regulation of Wnt signaling pathway [inference]

negative regulation of canonical Wnt signaling pathway

regulation of Wnt signaling pathway [inference]

negative regulation of Wnt signaling pathway [inference]

negative regulation of canonical Wnt signaling pathway

regulation of canonical Wnt signaling pathway [inference]

negative regulation of canonical Wnt signaling pathway

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of Wnt signaling pathway [inference]

negative regulation of canonical Wnt signaling pathway

regulation of cellular metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

regulation of RNA metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

positive regulation of transcription, DNA-templated

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of fibroblast growth factor production

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of transforming growth factor beta production [inference]

positive regulation of transforming growth factor beta2 production

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

negative regulation of cytokine production [inference]

negative regulation of fibroblast growth factor production

positive regulation of cytokine production [inference]

positive regulation of transforming growth factor beta production [inference]

positive regulation of transforming growth factor beta2 production

regulation of transforming growth factor beta production [inference]

regulation of transforming growth factor beta2 production [inference]

positive regulation of transforming growth factor beta2 production

positive regulation of transforming growth factor beta production [inference]

positive regulation of transforming growth factor beta2 production

regulation of fibroblast growth factor production [inference]

negative regulation of fibroblast growth factor production

regulation of DNA-templated transcription [inference]

positive regulation of transcription, DNA-templated

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of transforming growth factor beta production [inference]

positive regulation of transforming growth factor beta2 production

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of fibroblast growth factor production

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of transforming growth factor beta production [inference]

positive regulation of transforming growth factor beta2 production

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of fibroblast growth factor production

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

positive regulation of transcription, DNA-templated

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of fibroblast growth factor production

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of transforming growth factor beta production [inference]

positive regulation of transforming growth factor beta2 production

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

regulation of cell population proliferation [inference]

negative regulation of cell population proliferation [inference]

regulation of mesenchymal cell proliferation [inference]

negative regulation of mesenchymal cell proliferation

regulation of stem cell proliferation [inference]

negative regulation of stem cell proliferation

regulation of programmed cell death [inference]

regulation of apoptotic process [inference]

positive regulation of apoptotic process [inference]

positive regulation of epithelial cell apoptotic process

regulation of epithelial cell apoptotic process [inference]

positive regulation of epithelial cell apoptotic process

positive regulation of programmed cell death [inference]

positive regulation of apoptotic process [inference]

positive regulation of epithelial cell apoptotic process

positive regulation of cellular process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of transforming growth factor beta production [inference]

positive regulation of transforming growth factor beta2 production

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of programmed cell death [inference]

positive regulation of apoptotic process [inference]

positive regulation of epithelial cell apoptotic process

negative regulation of cellular process [inference]

negative regulation of cell population proliferation [inference]

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of Wnt signaling pathway [inference]

negative regulation of canonical Wnt signaling pathway

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of fibroblast growth factor production

regulation of multicellular organismal process [inference]

regulation of cytokine production [inference]

negative regulation of cytokine production [inference]

negative regulation of fibroblast growth factor production

positive regulation of cytokine production [inference]

positive regulation of transforming growth factor beta production [inference]

positive regulation of transforming growth factor beta2 production

regulation of transforming growth factor beta production [inference]

regulation of transforming growth factor beta2 production [inference]

positive regulation of transforming growth factor beta2 production

positive regulation of transforming growth factor beta production [inference]

positive regulation of transforming growth factor beta2 production

regulation of fibroblast growth factor production [inference]

negative regulation of fibroblast growth factor production

positive regulation of multicellular organismal process [inference]

positive regulation of cytokine production [inference]

positive regulation of transforming growth factor beta production [inference]

positive regulation of transforming growth factor beta2 production

negative regulation of multicellular organismal process [inference]

negative regulation of cytokine production [inference]

negative regulation of fibroblast growth factor production

negative regulation of cartilage development

regulation of multicellular organismal development [inference]

regulation of cartilage development [inference]

negative regulation of cartilage development

Displaying **all 4** entries
GO Term	Evidence Code	PMID
extracellular region	TAS
extracellular space	IBA
cytoplasm	IDA	20103596 20219091
extracellular matrix	IEA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

external encapsulating structure [inference]

extracellular matrix

Displaying **all 5** entries
GO Term	Evidence Code	PMID
frizzled binding	NAS	24431302
frizzled binding	IBA
cytokine activity	IBA
protein binding	IPI	25416956 30886144 32296183
protein kinase activator activity	IMP	20219091

GO Hierarchy

molecular function

binding [inference]

protein binding

signaling receptor binding [inference]

G protein-coupled receptor binding [inference]

frizzled binding

receptor ligand activity [inference]

cytokine activity

molecular function regulator activity [inference]

enzyme regulator activity [inference]

enzyme activator activity [inference]

kinase activator activity [inference]

protein kinase activator activity

kinase regulator activity [inference]

kinase activator activity [inference]

protein kinase activator activity

protein kinase regulator activity [inference]

protein kinase activator activity

signaling receptor regulator activity [inference]

signaling receptor activator activity [inference]

receptor ligand activity [inference]

cytokine activity

molecular function activator activity [inference]

enzyme activator activity [inference]

kinase activator activity [inference]

protein kinase activator activity

signaling receptor activator activity [inference]

receptor ligand activity [inference]

cytokine activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Wnt

Functional Category

J: Translation, ribosomal structure and biogenesis
K: Transcription
T: Signal transduction mechanisms

Displaying **all 5** entries
Gene Ontology
canonical Wnt signaling pathway
cell fate commitment
cytokine activity
neuron differentiation
signaling receptor binding

Displaying **all 3** entries
InterPro
Wnt protein, conserved site
Wnt, C-terminal domain
Wnt

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:0050866	oral squamous cell carcinoma	Alliance of Genome Resources

Ortholog

Displaying entries **1 - 10** of 80 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Caenorhabditis elegans	7480	WB:WBGene00003029
Xenopus tropicalis	7481	Xenbase:XB-GENE-854158
Caenorhabditis elegans	7484	WB:WBGene00003029
Caenorhabditis elegans	22409	WB:WBGene00003029
Mus musculus	22411	Xenbase:XB-GENE-854158	MOUSE54883
Danio rerio	30283		DANRE01249
Caenorhabditis elegans	30308	WB:WBGene00003029
Caenorhabditis elegans	80326	WB:WBGene00003029
Rattus norvegicus	140584		RATNO17038
Danio rerio	171994	ZFIN:ZDB-GENE-980526-249

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

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Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements